Gilmer
Chad Gilmer, Dublin IE
Patent application number | Description | Published |
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20080301127 | Method and Apparatus for Providing an On-Line Directory Service - A method and apparatus for providing an on-line directory service is described. By providing search results in a graphical tapestry it is possible to provide more search results on a browser window, thereby minimising the requirement for a user to scroll through a sequential listing. The search results are provided in a graphical format, each of the resultant graphics being dimensioned appropriately depending on its ranking within the search results. | 12-04-2008 |
David Gilmer, Strasbourg FR
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20090265808 | P15 HAIRPIN CONSTRUCTS AND USE - The present invention concerns a method of genetic modification of a TGB-3 wild type viral sequence for reducing or suppressing the possible deleterious effects of the agronomic properties of a transformed plant or plant cell by said TGB-3 viral sequence. The invention further relates to genetically modified TGB-3 viral sequences suitable to induce gene silencing. In particular hairpin constructs based on such sequences proved highly efficient to induce a PTGS mechanism and degradation of the whole of RNA2 thereby. When plants are transformed accordingly the spread of the virus in the plant is significantly reduced or blocked. | 10-22-2009 |
20140317779 | P0 GENE SILENCING CONSTRUCTS AND USE - A recombinant BMYV P0 viral nucleotide sequence when transcribed in a cell is capable of forming a double stranded self-complementary RNA sequence. | 10-23-2014 |
John Gilmer, Tallaght IE
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20120082634 | TREATMENT FOR DYSLIPIDEMIA - The present invention relates to compounds, and compositions, useful for treating dyslipidemia. | 04-05-2012 |
John Gilmer, Co. Dublin IE
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20160073668 | COMPOSITIONS AND METHODS FOR INCREASING IRON INTAKE IN A MAMMAL - Compositions containing iron and denatured protein have been prepared that are capable of increasing serum iron and other divalent metal cations in a subject. For example, edible microbeads have been prepared containing iron entrapped within a protein matrix that provides a gastroprotective effect and improves iron bioavailability relative to previously known vehicles for delivering iron to a subject. | 03-17-2016 |
John Gilmer, Dublin IE
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20130338118 | COMPOUNDS FOR TREATMENT OF HEART FAILURE - A combination of: a first tetracycline (TC) component; and a second component capable of releasing nitric oxide (NO) or a nitrate capable of mimicking NO effects in vivo (NO mimetic). The combinations of the invention advantageously act as more effective MMP modulators with selective reductions in circulating MMP-9 levels in-vivo and inhibitory effects on MMP-2 and MMP-9 levels in-vitro. The combinations of the invention also advantageously act as modulators of inflammation mediators. The co-existence of abnormalities of MMP enzymes and inflammation in many diseases make these characteristics advantageous. Therefore, the various combinations of the invention find utility in medical applications where MMPs and/or inflammation is implicated. | 12-19-2013 |
John Francis Gilmer, Dublin IE
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20090082314 | Targeting Prodrugs for the Treatment of Gastrointestinal Diseases - Provided herein are compounds, compositions and methods for decreasing NFκB DNA-binding activity in a patient comprising administering of a therapeutically effective amount of a compound or composition of the application to the patient to reduce, alleviate or treat various gastrointestinal diseases, such as inflammatory bowel disease (IBD). | 03-26-2009 |
20110046182 | EFFICIENT ASPIRIN PRODRUGS - Aspirin is one of the most widely used drugs in the treatment of inflammation, pain and fever. It has more recently found application in the prevention of heart attacks and stroke and is being studied as a cancer chemopreventative agent. Despite its value aspirin continues to be underutilized because it causes gastric bleeding. The technology under development potentially removes this problem. It is designed to reduce contact between the drug and the intestinal lining. An isosorbide aspirinate prodrug compound is thus provided. The compound has the general structure as shown in general formula (I) wherein Y is a C | 02-24-2011 |
20120094963 | TARGETING PRODRUGS AND COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL DISEASES - Provided herein are compounds of formula (I) as well as compounds of formula (I) which are prodrugs in which the (R7)a-phenyl-S(O)2NH group represents a sulphonamide-bond compound, compositions and methods for preventing or treating gastrointestinal diseases such as inflammatory bowel disease and colorectal cancer, wherein the method comprises delivering an effective amount of a COX-2 or a similar sulphonamide inhibitor as a prodrug or a derivative thereof to the colon, wherein the COX-2 or similar inhibitor is released in vivo. | 04-19-2012 |
20140024681 | COMPOUNDS WITH SUPER-ASPIRIN EFFECTS - A compound having the structural formula (I) and pharmaceutically acceptable salt and/or hydrates thereof, (I) wherein Y is an arylester or an C | 01-23-2014 |
20150291615 | COMPOUNDS WITH SUPER-ASPIRIN EFFECTS - A compound having the structural formula (I) and pharmaceutically acceptable salt and/or hydrates thereof, (I) wherein Y is an arylester or an C | 10-15-2015 |
Jurgen Gilmer, Rauschenberg DE
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20120010034 | TRACTION MECHANISM DRIVE HAVING A VIBRATION DAMPER - A traction mechanism drive, in particular for an internal combustion engine, including a vibration damper ( | 01-12-2012 |
Paula Gilmer, Dublin IE
Patent application number | Description | Published |
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20080301127 | Method and Apparatus for Providing an On-Line Directory Service - A method and apparatus for providing an on-line directory service is described. By providing search results in a graphical tapestry it is possible to provide more search results on a browser window, thereby minimising the requirement for a user to scroll through a sequential listing. The search results are provided in a graphical format, each of the resultant graphics being dimensioned appropriately depending on its ranking within the search results. | 12-04-2008 |