| Patent application number | Description | Published |
| 20090099627 | THERAPY CONTROL BASED ON A PATIENT MOVEMENT STATE - A movement state of a patient is detected based on brain signals, such as an electroencephalogram (EEG) signal. In some examples, a brain signal within a dorsal-lateral prefrontal cortex of a brain of the patient indicative of prospective movement of the patient may be sensed in order to detect the movement state. The movement state may include the brain state that indicates the patient is intending on initiating movement, initiating movement, attempting to initiate movement or is actually moving. In some examples, upon detecting the movement state, a movement disorder therapy is delivered to the patient. In some examples, the therapy delivery is deactivated upon detecting the patient is no longer in a movement state or that the patient has successfully initiated movement. In addition, in some examples, the movement state detected based on the brain signals may be confirmed based on a signal from a motion sensor. | 04-16-2009 |
| 20100049323 | Artificial Intervertebral Joint Permitting Translational and Rotational Motion - An intervertebral joint prosthesis having a ball component ( | 02-25-2010 |
| 20110245798 | Method of Treating Parkinson's Disease in Humans by Convection-Enhanced Infusion of Glial Cell-Line Derived Neurotrophic Factor to the Putamen - A method of treating Parkinson's disease in humans is disclosed, wherein glial cell-line derive neurotrophic factor (GDNF) is chronically administered directly to one or both putamen of a human in need of treatment thereof via convection-enhanced infusion using at least one implantable pump and at least one catheter. In one aspect of the present invention the GDNF is infused directly into one or both putamen through one or more indwelling intraparenchymal mutitiport brain catheters connected to one or moreimplantable pumps wherein the flow rate is pulsed. | 10-06-2011 |
| Patent application number | Description | Published |
| 20090011980 | Method of Treating Parkinson's Disease in Humans by Direct Infusion of Glial Cell-Line Derived Neurotrophic Factor Into the Zona Incerta - A method of treating Parkinson's disease in humans is disclosed, wherein glial cell-line derive neurotrophic factor (GDNF) is chronically administered directly to the SNc and at least one subthalamic region or, alternatively, to the SNc, at least one sub thalamic region, and at least one putaminal region of the brain of a human in need of treatment thereof. In one aspect of the present invention the GDNF is infused directly into at least one caudal zona incerta and at least one postero-dorsal putamen of the brain through indwelling intraparenchymal brain catheters connected to an implantable pump. | 01-08-2009 |
| 20090030373 | Method and Apparatus for Fluid Delivery - Fluid delivery apparatus is described for the delivery of fluids to regions of the body, especially for delivery to regions of the brain. The apparatus includes a first length of implantable tubing having a first end and a first fluid connector portion attached to the first end of the first length of implantable tubing. The first fluid connector portion is releaseably connectable to a complementary second fluid connector portion. An implantable housing is also provided for enclosing and protecting the first fluid connector portion. The implantable housing is openable to provide access to the first fluid connector portion. For example, the housing may have a hinged lid or cover portion. A corresponding method is also described. | 01-29-2009 |
| 20090048508 | Rf coil assembly for use in magnetic resonance imaging - An RF coil assembly for use with magnetic resonance imaging (MRI) apparatus is described. The RF coil assembly comprises one or more coil elements capable of receiving electromagnetic radiation and is capable of being directly attached to a stereotactic base ring. The RF coil assembly may comprise a localiser box having fiducial markers. A corresponding attachment apparatus is also described for optimising the attachment position of a stereotactic base ring to a subject's head. The attachment apparatus comprises one or more fixing elements that allow the attachment apparatus to be releasably attached to a stereotactic base ring. In one embodiment, the internal dimensions of the attachment apparatus are selected to be substantially the same as the internal dimensions of an RF coil assembly. Corresponding methods are also described. | 02-19-2009 |
| 20090082758 | Implantable Fluid Distribution Device and Method of Fluid Delivery - An implantable fluid distribution device is described. The device includes a first inlet for receiving fluid under pressure from a remote pump. A plurality of outlets are also provided, each outlet being connectable to a fluid delivery catheter. A valve mechanism is arranged to control the passage of fluid from the first inlet to the plurality of outlets. Apparatus including the fluid distribution device, an implantable pump and a plurality of drug delivery catheters is also described. The fluid distribution device can be used to delivery drug to multiple regions in the body and the sequential delivery of drugs to different sites in the brain is disclosed. | 03-26-2009 |
| 20100042070 | NEUROLOGICAL APPARATUS COMPRISING A PERCUTANEOUS ACCESS DEVICE - Apparatus for delivering therapeutic agents to the central nervous system of a subject is described. The apparatus comprises at least one intracranial catheter and a percutaneous access device. The percutaneous access device comprises a body having at least one extracorporeal surface and at least one subcutaneous surface, the body defining at least one port for connection to an implanted intracranial catheter. The port is accessible from the extracorporeal surface of the device, but is provided with a seal such as a rubber bung between the lumen of the port and the extracorporeal surface. The percutaneous access device may have more than two ports and/or a flange. A method of implanting the percutaneous access device is also described. | 02-18-2010 |
| 20110009879 | APPARATUS FOR STEREOTACTIC NEUROSURGERY - A skull mount ( | 01-13-2011 |
| 20110131808 | BRAIN ELECTRODE - An electrode, in particular a deep brain stimulating (DBS) electrode or a deep brain lesioning electrode, a method for manufacturing an electrode and use of the electrode, and a directional electrode. | 06-09-2011 |