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Gijsbertus J.

Gijsbertus J. Kerpershoek, Barendrecht NL

Patent application numberDescriptionPublished
20100002842CATHODE ASSEMBLY FOR RAPID ELECTRON SOURCE REPLACEMENT IN A ROTATING ANODE X-RAY GENERATOR - A cathode assembly for a rotating anode X-ray source comprises two parts: a focusing part that is mechanically connected to the remainder of the X-ray source and permanently aligned with respect to the anode and a separate emission part that holds the electron source and is removably connected to the focusing part. The electron source is permanently mounted in the emission part and precisely aligned to the focusing part. The focusing part and the emission part are mechanically connected aligned relative to one another at the time of replacement. This arrangement allows the emission part, including the electron source to be quickly removed and replaced by an inexperienced user while maintaining the accuracy of the X-ray source alignment.01-07-2010

Patent applications by Gijsbertus J. Kerpershoek, Barendrecht NL

Gijsbertus J. Pronk, Arvada, CO US

Patent application numberDescriptionPublished
20100248249Methods for Assessing Cancer for Increased Sensitivity to 10-Propargyl-10-Deazaaminopterin by Assessing Egfr Levels - The present invention relates to a method for assessing the sensitivity of a patient's cancer to treatment with 10-propargyl-10-deazaminopterin and a method for selecting a patient for treatment of cancer with 10-propargyl-10-deazaminopterin, by determining the amount of a EGFR or other growth factor expressed by the cancer and comparing the amount with the amount of EGFR or other growth factor expressed by a reference cancer.09-30-2010

Gijsbertus J. Pronk, Westminster, CO US

Patent application numberDescriptionPublished
20110190305Optically Pure Diastereomers of 10-Propargyl-10-Deazaaminopterin and Methods of Using Same - The present invention relates to diastereomers of 10-propargyl-10-deazaminopterin, compositions comprising optically pure diastereomers of 10-propargyl-10-deazaminopterin, in particular the two (R,S) diastereomers about the C10 position. Methods of preparation of these diastereomers, compositions containing them, and their use for the treatment of conditions related to inflammatory disorders and cancer are also disclosed.08-04-2011