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Gibiansky
Ekaterina Gibiansky, North Potomac, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090221532 | Methods Of Dosing Propofol Prodrugs For Inducing Mild To Moderate Levels Of Sedation - A dosage of a propofol prodrug needed for inducing mild to moderate sedation levels in a patient is calculated based on a patient's lean body mass. It has been discovered dosages based on gross body mass may result in overdosing, particularly for obese patients. In another aspect, a dosage suitable for inducing mild to moderate sedation levels in a patient who is at least 60 years of age is determined. A weight-appropriate dosage for the patient is determined and then adjusted by an age-based factor. For example, the dosage needed to produce a sedated state or other effect in a patient who is 60 years of age or older may be about 0.6-0.8 times the dosage needed to produce a corresponding effect in a younger patient of the same weight. | 09-03-2009 |
Leonid Gibiansky, N. Potomac, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090313087 | METHOD FOR OPTIMIZING NET PRESENT VALUE OF A CROSS-SELLING MARKETING CAMPAIGN - The present invention applies a novel iterative algorithm to the problem of multidimensional optimization by supplying a strict, nonlinear mathematical solution to what has traditionally been treated as a linear multidimensional problem. The process consists of randomly selecting a statistically significant sample of a prospect list, calculating the value of the utility function for each pair of an offer and selected prospects, reducing the original linear multidimensional problem to a non-linear problem with a feasible number of dimensions, solving the non-linear problem for the selected sample numerically with the desired tolerance using an iterative algorithm, and using the results to calculate an optimal set of offers in one pass for the full prospect list. | 12-17-2009 |
Leonid Gibiansky, North Potomac, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090221532 | Methods Of Dosing Propofol Prodrugs For Inducing Mild To Moderate Levels Of Sedation - A dosage of a propofol prodrug needed for inducing mild to moderate sedation levels in a patient is calculated based on a patient's lean body mass. It has been discovered dosages based on gross body mass may result in overdosing, particularly for obese patients. In another aspect, a dosage suitable for inducing mild to moderate sedation levels in a patient who is at least 60 years of age is determined. A weight-appropriate dosage for the patient is determined and then adjusted by an age-based factor. For example, the dosage needed to produce a sedated state or other effect in a patient who is 60 years of age or older may be about 0.6-0.8 times the dosage needed to produce a corresponding effect in a younger patient of the same weight. | 09-03-2009 |