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Gertler

Arieh Gertler, Rehovot IL

Patent application numberDescriptionPublished
20130133089HIGH AFFINITY LEPTINS AND LEPTIN ANTAGONISTS - Leptin muteins, in particular leptin antagonists, with increased binding affinity to leptin receptor are provided. These compounds as well as pharmaceutical composition comprising them are useful for the treatment of any disorder in which a non-desirable or deleterious activity of endogenous leptin or an altered innate immune response is implicated.05-23-2013

Frank Gertler, Boston, NY US

Patent application numberDescriptionPublished
20100047240Metastasis specific splice variants of mena and uses thereof in diagnosis, prognosis and treatment of tumors - Methods and kits for diagnosis, prognosis and treatment of metastatic tumors are provided where the metastatic tumor is characterized by changes in expression of +++, ++ and/or 11a variants of Mena.02-25-2010

Frank B. Gertler, Boston, MA US

Patent application numberDescriptionPublished
20110059470Tumor Microenvironment of metastasis (TMEM) and uses thereof in diagnosis, prognosis and treatment of tumors - Disclosed are methods for determining the risk of tumor cells undergoing metastasis, for assessing the prognosis of a subject undergoing treatment for a localized tumor, and for determining a course of treatment for a localized tumor comprising detecting the presence of an endothelial cell, a macrophage, and an invasive tumor cell in direct apposition in a tumor sample from a subject.03-10-2011

Ifat Gertler, Tel Aviv IL

Patent application numberDescriptionPublished
20120041523SKIN TREATMENT DEVICE UTILIZING LIGHT AND TEMPERATURE - A hand held device for treatment of a skin treatment area, constituted of: a housing exhibiting an opening therein; a temperature adjusting element secured to an end of the housing, one end of the temperature adjusting element arranged to contact the skin treatment area, the temperature adjusting element exhibiting at least one aperture; a light source secured to the housing; and a light path arranged to pass light energy from the light source to at least a portion of the skin treatment area via the at least one aperture. A pulsed light energy is provided to the portion of the skin treatment area from the light source proceeding through the aperture and the temperature adjusting element is powered so as to adjust the temperature of the skin treatment area.02-16-2012

Susan Gertler, Teaneck, NJ US

Patent application numberDescriptionPublished
20090311657System and method for providing differentiated content based on skill level - A system and method is disclosed for providing differentiated content to a user comprising determining a skill level of the user, obtaining unmodified content, aligning the unmodified content to a set of content standards, modifying the aligned content in accordance with the user's skill level, providing the modified aligned content to the user, re-assessing the user's skill level based on a response from the user to the modified aligned content, and modifying new aligned content in accordance with the re-assessed user's skill level.12-17-2009