| Patent application number | Description | Published |
|---|
| 20080245136 | Closed Loop Flow Control of a Hplc Constant Flow Pump To Enable Low-Flow Operation - A method and apparatus for monitoring and controlling nano-scale flow rate of fluid in the operating flow path of a HPLC system provide fluid flow without relying on complex calibration routines to compensate for solvent compositions gradients typically used in HPLC. The apparatus and method are used to correct the flow output of a typical, analytical-scale (0.1-5 mL/min) HPLC pump to enable accurate anti precise flow delivery at capillary (<0.1 mL/min) and nano-scale (<μL/min) HPLC flow rates. | 10-09-2008 |
| 20080283134 | Variable Resistance Fluid Controller - A fluid controller apparatus controls fluid flow, such as a solvent gradient flow, in a chromatography system. An apparatus includes a fluid-gradient controller having a fluid reservoir for containing a pump fluid and a pumping device connected to the fluid reservoir for receiving the pump fluid. The pumping device is in fluid communication with parallel-configured first and second solvent lines. The first and second solvent lines each contain a restrictor element and a solvent reservoir. During operation, the pumping device causes the pump fluid to flow through the first and second solvent lines in relation to their respective restriction devices. The pump fluid displaces solvent within the solvent reservoirs. The displaced solvent is mixed to form a solvent gradient. | 11-20-2008 |
| 20080302423 | Temperature-Controlled Variable Fluidic Resistance Device - A thermally controlled variable restrictor device provides variable restriction of fluid flow by temperature-induced viscosity changes. The thermally controlled variable restrictor device allows fast variable fluid control by employing a thermo-electric heater-cooler in intimate contact with a fluid channel containing a fluid thereby effecting rapid viscosity changes in the flowing fluid. The permeability and flow rate of fluids through the variable restrictor device can be manipulated by changing the temperature of a restriction element. | 12-11-2008 |
| 20090321356 | CERAMIC-BASED CHROMATOGRAPHY APPARATUS AND METHODS FOR MAKING SAME - A high-performance liquid-chromatography apparatus includes a substrate that defines a separation column in fluidic communication with an inlet port of the processing unit. The processing unit is formed of sintered inorganic particles. The apparatus also includes a pump that delivers a solvent to the inlet port at a pressure sufficient for high-performance liquid-chromatography. | 12-31-2009 |
| 20100018928 | DEVICE FOR PERFORMING SEPARATIONS AND METHODS OF MAKING AND USING SAME - Embodiments of the present invention feature a device ( | 01-28-2010 |
| 20100116745 | Closed Loop Flow Control Of A HPLC Constant Flow Pump To Enable Low-Flow Operation - A method and apparatus for monitoring and controlling nano-scale flow rate of fluid in the operating flow path of a HPLC system provide fluid flow without relying on complex calibration routines to compensate for solvent composition gradients typically used in HPLC. The apparatus and method are used to correct the flow output of a typical, analytical-scale (0.1-5 mL/min) HPLC pump to enable accurate and precise flow delivery at capillary (<0.1 mL/min) and nano-scale (<1 μL/min) HPLC flow rates. | 05-13-2010 |
| 20100158704 | COMPLIANT-SEAL CHECK VALVE - A check valve includes a valve seat and a compliant member that moves to seal the check valve by contacting the valve seat. A method for priming a chromatography solvent pump includes providing the check valve in fluid communication with an outlet of the pump, drawing fluid into the pump from a fluid source, and expelling the fluid from the pump through the valve, thus wetting the check valve. Another method for priming a chromatography solvent pump includes providing the check valve in fluid communication with an inlet of the pump, drawing fluid through the valve into the pump, and expelling the fluid from the pump. | 06-24-2010 |
| 20110107822 | Interfacing With A Digital Microfluidic Device - Described are techniques for use in connection with analyzing a droplet. One or more droplets of a sample are formed on a surface of a digital microfluidic device. The droplets are manipulated to perform processing using said one or more droplets generating one or more resulting droplets. The one or more resulting droplets may be transferred from the microfluidic device to another device for analysis. The one or more droplets may also be provided to the digital microfluidic device from yet another device or analysis instrument. | 05-12-2011 |
