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Geng, US
Bolin Geng, Waltham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100144717 | 2-QUINOLINONE AND 2-QUINOXALINONE-DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS - The present invention relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, to their use in the treatment of bacterial infections, and to their methods of preparation. | 06-10-2010 |
| 20100152441 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS - The present invention relates to compounds that demonstrate antibacterial activity, processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment of bacterial infections in warm-blooded animals such as humans. In particular this invention relates to compounds useful for the treatment of bacterial infections in warm-blooded animals such as humans, more particularly to the use of these compounds in the manufacture of medicaments for use in the treatment of bacterial infections in warm-blooded animals such as humans. | 06-17-2010 |
| 20110092495 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS - The present invention relates to compounds that demonstrate antibacterial activity, processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment of bacterial infections in warm-blooded animals such as humans. In particular this invention relates to compounds useful for the treatment of bacterial infections in warm-blooded animals such as humans, more particularly to the use of these compounds in the manufacture of medicaments for use in the treatment of bacterial infections in warm-blooded animals such as humans. | 04-21-2011 |
| 20110288084 | [4-( 1-AMINO-ETHYL) - CYCLOHEXYL ] - METHYL - AMINES AS ANTIBACTERIALS - The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts thereof, to their use in the treatment of bacterial infections, and to their methods of preparation. | 11-24-2011 |
| 20120108577 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS - The present invention relates to compounds that demonstrate antibacterial activity, processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment of bacterial infections in warm-blooded animals such as humans. In particular this invention relates to compounds useful for the treatment of bacterial infections in warm-blooded animals such as humans, more particularly to the use of these compounds in the manufacture of medicaments for use in the treatment of bacterial infections in warm-blooded animals such as humans. | 05-03-2012 |
| 20120270864 | 2-QUINOLINONE AND 2-QUINOXALINONE-DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS - The present invention relates to compounds of Formula (I): | 10-25-2012 |
Chaoxian Geng, Westford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100212029 | NOVEL ASSAYS UTILIZING NICOTINIC ACETYLCHOLINE RECEPTOR SUBUNITS - The present invention is in the field of identification and characterization of novel insecticidal target sites and, in particular, relates to host cells, assays and antibodies thereto. | 08-19-2010 |
Chaoxian Geng, Zionsville, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20120174258 | NUCLEIC ACID MOLECULES THAT CONFER RESISTANCE TO COLEOPTERAN PESTS - This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby. | 07-05-2012 |
| 20120174259 | NUCLEIC ACID MOLECULES THAT TARGET THE VACUOLAR ATPASE C SUBUNIT AND CONFER RESISTANCE TO COLEOPTERAN PESTS - This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby. | 07-05-2012 |
| 20120174260 | NUCLEIC ACID MOLECULES THAT TARGET THE RHO1 SMALL GTP-BINDING PROTEIN AND CONFER RESISTANCE TO COLEOPTERAN PESTS - This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby. | 07-05-2012 |
| 20120198586 | NUCLEIC ACID MOLECULES THAT TARGET THE VACUOLAR ATPASE H SUBUNIT AND CONFER RESISTANCE TO COLEOPTERAN PESTS - This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby. | 08-02-2012 |
Feng Geng, Columbus, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20130072554 | Novel Method For Delivery and Use of Isothiocyanates For Prophylaxis and/or Therapy of Bladder Cancer - Provided is a composition that contains a mixture of broccoli seed and mustard seed. Before mixing the broccoli seed with the mustard seed, the broccoli seed is subjected to baking and a pressurized heat treatment. The broccoli seed is baked at a temperature of at least 200 degrees Fahrenheit for at least 60 minutes, and is subjected to a pressurized heat treatment of at least 200 degrees Fahrenheit at a pressure of at least 10 pounds/square inch for at least 5 minutes. Also provided is a method for therapy and/or prophylaxis of bladder cancer in an individual. The method entails administering orally to the individual a composition that contains an isothiocyanate (ITC) or a derivative thereof such that the administration inhibits the growth and/or recurrence of bladder cancer. Nutraceutical compositions are also provided. | 03-21-2013 |
Feng Geng, Piscataway, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100145107 | NOVEL PROPANOL AND RELATED COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS - The present invention a method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of a compound of formula: | 06-10-2010 |
| 20110286964 | AZO-SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS - The present invention provides compounds of Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R | 11-24-2011 |
| 20110286965 | ETHENYL-SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS - The present invention provides compounds of Formula (A): (Chemical formula should be inserted here as it appears on abstract in paper form) (A) and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein wherein each of R, R | 11-24-2011 |
| 20110318305 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS - The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R | 12-29-2011 |
| 20120041214 | HEXAHYDRO ETHANOCHROMENES AND RELATED COMPOUNDS AND THEIR USE IN FRAGRANCE COMPOSITIONS - The present invention relates to novel compounds and their use in fragrance compositions. Novel hexahydro ethanochromene and related hexahydro ethanochromane compounds of the present invention are represented by formula: | 02-16-2012 |
| 20120107271 | ETHYNYL-SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS - The present invention provides compounds of Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and pro-drugs of said compounds, wherein each of R, R | 05-03-2012 |
Haifeng Geng, Baltimore, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100035960 | BIOSYNTHETIC PATHWAY AND GENES REQUIRED FOR TROPODITHIETIC ACID BIOSYNTHESIS IN SILICIBACTER TM1040 - Production and use of a sulfur-containing compound, tropodithietic acid (TDA), from the | 02-11-2010 |
Huaizhi Geng, Cary, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090078914 | Methods and devices for electrophoretic deposition of a uniform carbon nanotube composite film - Methods and devices are provided relating to the homogeneous deposition of a composite film of carbon nanotubes by electrophoresis. The methods comprise linking carbon nanotubes to matrix particles prior to electrophoretic deposition. The methods improve the adhesion of the composite film to the substrate and reduce the surface roughness. Carbon nanotube films and electron field emission cathodes fabricated by this process demonstrate enhanced electron field emission characteristics. | 03-26-2009 |
Jihong Geng, Tucson, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20110019700 | MODE-LOCKED TWO MICRON FIBER LASERS - A mode-locked fiber laser comprising a multicomponent glass fiber doped with a trivalent rare-earth ion of thulium and/or holmium. | 01-27-2011 |
| 20110222562 | Mode-Locked Two-Micron Fiber Lasers - A mode-locked fiber laser comprising a multicomponent glass fiber doped with a trivalent rare-earth ion of thulium and/or holmium and including a fiber-optic based passive saturable absorber that contains an adhesive material mixed with a saturable absorbing components and is disposed along the length of an optical fiber such as to assure that a mode propagating within the fiber spatially overlaps with the volume occupied by the saturable absorbing components. | 09-15-2011 |
| 20110261454 | All-Fiber Optical Isolator - An all-fiber Faraday rotator including a plurality of optical fibers doped, at unusually high concentrations of at least several tens of percent, with rare-earth oxides, an all-optical-fiber optical isolator employing a polarization-maintaining fiber-optic splitter, and a method of optically-isolating a laser source from unwanted feedback with such an optical isolator. In a case where the doping concentration exceeds 55 weight-%, the length of the Faraday rotator achieving a 45-degree rotation of the polarization vector of light guided by an optical fiber does not exceed approximately 10 cm. | 10-27-2011 |
Jinming Geng, Scarborough, ME US
| Patent application number | Description | Published |
|---|---|---|
| 20090286229 | Methods, Devices, Kits and Compositions for Detecting Roundworm - Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, whipworm, and heartworm. Confirmation of the presence or absence of roundworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated. | 11-19-2009 |
| 20090286231 | Methods, Devices, Kits and Compositions for Detecting Roundworm, Whipworm, and Hookworm - Methods, devices, kits and compositions for detecting the presence or absence of one or more helminthic coproantigens in a sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm, whipworm and/or hookworm in a fecal sample from a mammal and may also be able to distinguish between one or more helminth infections. Confirmation of the presence or absence of roundworm, whipworm and/or hookworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated. | 11-19-2009 |
| 20100151500 | Compositions, Devices, Kits and Methods for Detecting Hookworm - Methods, devices, kits and compositions for detecting the presence or absence of hookworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of hookworm in a fecal sample from a mammal that may also be infected with one or more of roundworm, whipworm, and heartworm. Confirmation of the presence or absence of hookworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated. | 06-17-2010 |
| 20110086340 | METHODS, DEVICES, KITS AND COMPOSITIONS FOR DETECTING ROUNDWORM - Methods, devices, kits and compositions for detecting the presence or absence of roundworm in a mammalian sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, whipworm, and heartworm. Confirmation of the presence or absence of roundworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated. | 04-14-2011 |
Kebin Geng, Rocky River, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20100292492 | CATALYSTS FOR ESTERIFICATION OF EPOXIDIZED SOYATES AND METHODS OF USING SAME - A combination of catalysts is disclosed as useful to promote the transesterification reaction of an epoxidized soyate with a polyol to yield a high percentage of epoxidized soyate diester with epoxy functionality retained. The primary catalyst is a metallic hydroxide, and the secondary catalyst is a titanate. Bioderived plasticizers useful for thermoplastics and thermosets result. | 11-18-2010 |
| 20100324185 | EPOXIDIZED SOYATE DIESTERS AND METHODS OF USING SAME - An unhindered polyol is used to react with an epoxidized soyate to make epoxidized soyate diester in the presence of a catalyst. The unhindered polyol can be 1,3-propanediol or any polyol having four or more carbon atoms with no two adjacent carbon atoms having hydroxyl functionality. Preferably, a combination of catalysts is used to promote the transesterification reaction of the epoxidized soyate with the unhindered polyol to yield a high percentage of epoxidized soyate diester with epoxy functionality retained. The primary catalyst is a metallic hydroxide, and the secondary catalyst is a titanate. Bioderived epoxidized soyate diester plasticizers useful for thermoplastics and thermosets result. | 12-23-2010 |
Leo Geng, Holliday, UT US
| Patent application number | Description | Published |
|---|---|---|
| 20090273940 | LED lighting device - The present invention is a light generation device utilizing higher efficiency LED's while also allowing for interface with current lighting interfaces. The LED's are replaceable in the unit and may be interchanged with other LED's to affect lighting mood and style or simply for replacement in the event an LED ceases to function. | 11-05-2009 |
Lifeng Geng, Cary, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090163493 | Benzene, Pyridine, and Pyridazine Derivatives - Disclosed are compounds and pharmaceutically acceptable salts of Formula I | 06-25-2009 |
| 20110034529 | BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES - Disclosed are compounds and pharmaceutically acceptable salts of Formula I | 02-10-2011 |
| 20110183977 | BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES - Disclosed are compounds and pharmaceutically acceptable salts of Formula I | 07-28-2011 |
Lijian Geng, Holliday, UT US
| Patent application number | Description | Published |
|---|---|---|
| 20100187964 | LED Lighting Device - The present invention is a light generation device utilizing higher efficiency LED's while also allowing for interface with current lighting interfaces. The LED's are replaceable in the unit and may be interchanged with other LED's to affect lighting mood and style or simply for replacement in the event an LED ceases to function. | 07-29-2010 |
Liping Geng, Newark, DE US
| Patent application number | Description | Published |
|---|---|---|
| 20100233725 | IMMUNOASSAYS EMPLOYING NON-PARTICULATE CHEMILUMINESCENT REAGENT - Methods and reagents are disclosed for conducting assays. Embodiments of the present methods and reagents are concerned with chemiluminescent reagents for determining the presence and/or amount of an analyte in a sample suspected of containing the analyte. The reagent is non-particulate and comprises a binding partner for the analyte and a chemiluminescent composition comprising an olefinic compound and a metal chelate. In embodiments of an assay, a combination is provided that comprises a sample suspected of containing the analyte, a chemiluminescent reagent as described above and a sensitizer reagent capable of generating singlet oxygen. The combination is subjected to conditions for binding of the analyte to the binding partner for the analyte. The sensitizer is activated and the amount of luminescence generated by the chemiluminescent composition is detected wherein the amount of luminescence is related to the amount of the analyte in the sample. | 09-16-2010 |
Mei Geng, Bedford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090221035 | SYSTEMS AND METHODS FOR PROTEIN PRODUCTION - The invention relates to systems and methods for producing proteins of interest. The invention employs genetically-engineered animal or plant cells that have modified protein folding or processing capacities. In one aspect, the invention features genetically-engineered cells comprising one or more recombinant expression cassettes which encode (1) a protein of interest and (2) a polypeptide that is functional in the unfolded protein response (UPR) pathway of the cells. Co-expression of the polypeptide significantly increases the yield of the protein of interest in the genetically-engineered cells. In one example, the genetically-engineered cells are animal cells, and the co-expressed polypeptide is a component or modulator of an XB1- or ATF6-mediated UPR pathway. | 09-03-2009 |
| 20120322104 | SYSTEMS AND METHODS FOR PROTEIN PRODUCTION - The invention relates to systems and methods for producing proteins of interest. The invention employs genetically-engineered animal or plant cells that have modified protein folding or processing capacities. In one aspect, the invention features genetically-engineered cells comprising one or more recombinant expression cassettes which encode (1) a protein of interest and (2) a polypeptide that is functional in the unfolded protein response (UPR) pathway of the cells. Co-expression of the polypeptide significantly increases the yield of the protein of interest in the genetically-engineered cells. In one example, the genetically-engineered cells are animal cells, and the co-expressed polypeptide is a component or modulator of an XBP1- or ATF6-mediated UPR pathway. | 12-20-2012 |
Mingming Geng, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090202904 | PASTED NICKEL HYDROXIDE ELECTRODE FOR RECHARGEABLE NICKEL-ZINC BATTERIES - Active material for a positive electrode of a rechargeable alkaline electrochemical cell is made with nickel hydroxide particles or cobalt-coated nickel hydroxide particles treated with strongly oxidizing reagents such as alkali metal persulfate in alkaline solution. The active material also may be made with cobalt-coated nickel hydroxide particles having a high percentage of cobalt(III) on a surface or an average cobalt oxidation state of about 3 measured across the particles. The treated nickel hydroxide or cobalt-coated nickel hydroxide decreases the cobalt solubility in the alkaline electrolyte and increases the high-rate charge and discharge capability. The lower cobalt solubility decreases cobalt migration that can increase self discharge and lead to premature failure. | 08-13-2009 |
| 20090208839 | NICKEL HYDROXIDE ELECTRODE FOR RECHARGEABLE BATTERIES - The nickel hydroxide particles for a nickel hydroxide electrode may be treated using an alkaline solution of a strong oxidizing agent such as sodium or potassium persulfate to modify the surface nickel hydroxide structure. The resulting modified surface structure has been found to impart various benefits to electrodes formed from the nickel hydroxide. It is believed that the oxidation of cobalt compounds at the surface of the nickel hydroxide particles results in a highly conductive cobalt compound that plays an important role in the high reliability, high stability and high capacity utilization of nickel electrodes as described herein. | 08-20-2009 |
| 20120018669 | PASTED NICKEL HYDROXIDE ELECTRODE FOR RECHARGEABLE NICKEL-ZINC BATTERIES - Active material for a positive electrode of a rechargeable alkaline electrochemical cell is made with nickel hydroxide particles or cobalt-coated nickel hydroxide particles treated with strongly oxidizing reagents such as alkali metal persulfate in alkaline solution. The active material also may be made with cobalt-coated nickel hydroxide particles having a high percentage of cobalt(III) on a surface or an average cobalt oxidation state of about 3 measured across the particles. The treated nickel hydroxide or cobalt-coated nickel hydroxide decreases the cobalt solubility in the alkaline electrolyte and increases the high-rate charge and discharge capability. The lower cobalt solubility decreases cobalt migration that can increase self discharge and lead to premature failure. | 01-26-2012 |
| 20120018670 | NICKEL HYDROXIDE ELECTRODE FOR RECHARGEABLE BATTERIES - The nickel hydroxide particles for a nickel hydroxide electrode may be treated using an alkaline solution of a strong oxidizing agent such as sodium or potassium persulfate to modify the surface nickel hydroxide structure. The resulting modified surface structure has been found to impart various benefits to electrodes formed from the nickel hydroxide. It is believed that the oxidation of cobalt compounds at the surface of the nickel hydroxide particles results in a highly conductive cobalt compound that plays an important role in the high reliability, high stability and high capacity utilization of nickel electrodes as described herein. | 01-26-2012 |
Peng Geng, Edison, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090043107 | Process for Synthesizing Compounds Useful for Treating Hepatitis C - The present disclosure generally relates to a process for synthesizing methyl ((1S)-1-(((2S)-2-(5-(4′-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3- methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt. The present disclosure also generally relates to intermediates useful in this process. | 02-12-2009 |
Shuo Geng, Toledo, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20120015040 | Dendritic Cell Precursor Populations, Dendritic Cell Populations Derived Therefrom and Uses Thereof - Dendritic cell precursor populations, dendritic cell populations derived therefrom, methods for isolating, expanding and using are disclosed. | 01-19-2012 |
Steven M. Geng, Parma, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20110175369 | Apparatus and methods for mitigating electromagnetic emissions - Apparatus, methods, and other embodiments associated with mitigation of magnetic fields are described herein. In an embodiment, a method for mitigating an electromagnetic field includes positioning a mitigating coil around a linear alternator of linear motor so that the mitigating coil is coaxially located with an alternator coil; arranging the mitigating coil to generate a field to mitigate an electromagnetic field generated by the alternator coil; and passing an induced current from the alternator coil through the mitigating coil. | 07-21-2011 |
Tao Geng, New Bern, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20120193337 | ELECTRIC OVEN WITH A HEATING ELEMENT REFLECTOR - An electric oven with a heating element designed to conduct broiling operations includes a reflector that is mounted between the heating element and a ceiling of a cooking cavity. The reflector can include reflecting portions that extend downward from side, rear or front edges of the reflector to help focus radiant energy produced by a heating element downward onto an underlying cooking surface. The reflector can also include a plurality of curved segments that are designed to reflect radiant energy emitted upward by the heating element back downward onto an underlying cooking surface. The curved segments can have varying focal lengths to help more evenly distribute the reflected radiant energy across the underlying cooking surface. | 08-02-2012 |
Wei Geng, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110025464 | Antenna Diversity For Wireless Tracking System And Method - The present invention provides a solution to determine a real-time location of an object in an indoor facility utilizing the spatial and angular antenna diversity on a sensor. Specifically, the spatial diversity is achieved by placing a second antenna a predetermined distance (which is greater than one-half of the wavelength) away from the first antenna. The angular diversity is obtained by placing the second antenna at ninety degrees (perpendicular) angle of the first antenna. | 02-03-2011 |
| 20120077514 | Wireless Tracking System And Method Utilizing Multiple Location Algorithms - The present invention provides a solution to mistaken location calculations based on multipath effects. The present invention determines a real-time location of an object in a facility using a combination of location algorithms, with a signal characteristic for a wireless signal from a communication device attached to the object received at a sensor of a mesh network. The location algorithms preferably include at least two of a proximity algorithm, a radial basis function algorithm, a maximum likelihood algorithm, a genetic algorithm, a minimum mean squared error algorithm, a radiofrequency fingerprinting algorithm, a multilateration algorithm, a time difference of arrival algorithm, a signal strength algorithm, a time of arrival algorithm, an angle of arrival algorithm, a spatial diversity algorithm, and a nearest neighbor algorithm | 03-29-2012 |
Wei Geng, Hercules, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080268420 | Isolating Human Antibodies - The invention is drawn to a method of isolating human antibodies. | 10-30-2008 |
Xin Geng, Urbana, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20080252392 | DISCRETE DITHERED FREQUENCY PULSE WIDTH MODULATION - A system is described for generating a discrete noise-shaped variable switching frequency signal that may be used to define a digital pulse width modulation (“PWM”) period. The system may define a switching frequency waveform that may be used to generate a current switching frequency signal as a function of a system clock. The system may quantize the current switching frequency signal to generate a discrete switching frequency signal that is realizable with the system clock. The system may detect quantization noise and input the noise into the current switching frequency signal to eliminate or reduce discrete tones at the switching frequencies of a PWM signal spectrum. | 10-16-2008 |
Yan Geng, Athens, GA US
Yan Geng, Langhorne, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090220614 | Thermo-Responsive Block Co-Polymers, and Use Thereof - Provided are thermo-responsive polymersomes, which display cold-controlled encapsulation near the physiological temperatures, and have a PDI less than 1.2. Morphology of the thermo-responsive polymersomes is a function of the weight fraction of the hydrophilic block in the block copolymer and the number average molecular weight (M | 09-03-2009 |
| 20100305201 | Method of Treating a Tumor and Biodistribution of a Drug Delivered by Worm-Like Filomicelles - Provided are filomicelle nanocarrier systems for the controlled transport and bioselective delivery of encapsulatable, cytotoxic active agents contained therein, particularly anticancer agents. Further provided are methods for controlling destabilization of the filomicelle membrane and the resulting hydrolysis-triggered, controlled release of the active agent(s) encapsulated therein by controlling the blend ratio (mol %) of hydrolysable PEO-block copolymer of the hydrophilic component(s) and of the more hydrophobic PEO-block copolymer component(s), wherein bioselective release of the encapsulated cytotoxic agents is distributed intracellularly, and wherein lowered dosage of the drug was delivered to the non-tumor organs. Thus, the filomicelle system offers enhanced tumor-selective biodistribution of a drug, and a reduced toxicity of the encapsulated drug to other organs. | 12-02-2010 |
Yong-Jian Geng, Houston, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20080311607 | Methods and Compositions for Regulation of Stem Cell Survival, Proliferation, and Differentiation by Protein Ubiquitination - Compositions and methods for regulating in vitro cell growth are disclosed, and for providing undifferentiated stem cells or embryonic cells that are suitable for transplantation into damaged tissues or organs, or for use in tissue repair. A representative method includes causing the overexpression or underexpression of GalT binding protein (GtBP), also referred to as GalT associated protein (GTAP), in a cell such that ubiquitination of at least one cellular protein associated with cell adhesion and/or cell-to-cell interaction is correspondingly increased or decreased, causing inhibition of cell growth when GTAP is overexpressed and causing enhanced cell growth when GTAP is underexpressed by the cell. As a result, growth of the cell is altered or regulated. | 12-18-2008 |
| 20110171681 | METHODS AND COMPOSITIONS FOR REGULATION OF STEM CELL SURVIVAL, PROLIFERATION, AND DIFFERENTIATION BY PROTEIN UBIQUITINATION - Compositions and methods for regulating in vitro cell growth are disclosed, and for providing undifferentiated stem cells or embryonic cells that are suitable for transplantation into damaged tissues or organs, or for use in tissue repair. A representative method includes causing the overexpression or underexpression of GalT binding protein (GtBP), also referred to as GalT associated protein (GTAP), in a cell such that ubiquitination of at least one cellular protein associated with cell adhesion and/or cell-to-cell interaction is correspondingly increased or decreased, causing inhibition of cell growth when GTAP is overexpressed and causing enhanced cell growth when GTAP is underexpressed by the cell. As a result, growth of the cell is altered or regulated. | 07-14-2011 |
Yong-Jian Geng, Pearland, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090210956 | COMPOSITION AND METHOD FOR CLUSTERIN-MEDIATED STEM CELL THERAPY FOR TREATMENT OF ATHEROSCLEROSIS AND HEART FAILURE - Methods and compositions are disclosed for inhibiting, deterring or preventing apoptosis of cardiac myocytes, transplanted stem cells, vascular stem cells, and vascular smooth muscle cells by means of expressing or synthesizing clusterin. Also disclosed are methods and compositions for producing recombinant clusterin, or its biologically active peptides, and for induction of clusterin-associated lipoproteins or enzymes for deterring or preventing inflammatory injury and apoptosis induced by oxLDL, oxysterols, cytokines, and Fas Ligand. Also disclosed is an induction method and composition for enhancing expression of ALDH and ALDH-associated enzymes or co-factors to prevent cytotoxicity or detoxification. Therapeutic methods providing new expression or overexpression of clusterin in vascular or cardiac tissue are expected to inhibit the formation of atherosclerotic lesions, stabilize existing atherosclerotic plaques, and repair failing or damaged cardiac tissue. | 08-20-2009 |
Zheng Jason Geng, Rockville, MD US
| Patent application number | Description | Published |
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| 20090010507 | SYSTEM AND METHOD FOR GENERATING A 3D MODEL OF ANATOMICAL STRUCTURE USING A PLURALITY OF 2D IMAGES - A system and method are provided for generating a three dimensional (3D) model of an anatomical structure of a patient using a plurality of two dimensional (2D) images acquired using a camera. The method includes the operation of searching the plurality of 2D images to detect correspondence points of image features across at least two images. Camera motion parameters can be determined using the correspondence points for a sequence of at least two images taken at different locations by the camera moving within the internal anatomical structure. A further operation is computing dense stereo maps for 2D image pairs that are temporally adjacent. A consistent 3D model can be formed by fusing together multiple 2D images which are applied to a plurality of integrated 3D model segments. Then the 3D model of the patient's internal anatomical structure can be displayed to a user on a display device. | 01-08-2009 |
| 20100020254 | MULTI-PANEL VIRTUAL IMAGE DISPLAY - A multiple panel system and method for displaying a virtual image viewable from multiple viewing angles is provided. Reflective viewing panels are arranged relative to one another in at least a partially closed enclosure arrangement. A display screen is oriented with respect to the viewing panels such that an image displayed on the display screen creates a virtual image viewable from multiple angles. An image formation mechanism is operable to display an image onto the display screen. | 01-28-2010 |