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Gene W.
Gene W. Arant, Lincoln City, OR US
| Patent application number | Description | Published |
|---|---|---|
| 20100024269 | Compact executive organizer, and method - A system and method of representing priorities of a number of information items in a manner which permits the priorities to be rearranged quickly and easily, utilizing individual display units supported on a parallel pair of rails, each display unit including an integrally formed display board and a note sheet removably attached to the board. | 02-04-2010 |
Gene W. Lee, Chelmsford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080311614 | METHODS FOR MEASURING PH IN A SMALL-SCALE CELL CULTURE SYSTEM AND PREDICTING PERFORMANCE OF CELLS IN A LARGE-SCALE CULTURE SYSTEM - The present invention is directed to methods/systems for measuring the pH of a cell culture medium in a small-scale system utilizing a pH-sensitive dye. The present invention is also directed to methods for predicting the performance of cells in a large-scale culture system. | 12-18-2008 |
| 20100029500 | OLIGONUCLEOTIDE ARRAYS TO MONITOR GENE EXPRESSION AND METHODS FOR MAKING AND USING SAME - The present invention provides an oligonucleotide array capable of identifying genes and related pathways involved with the induction of a particular phenotype by a cell line, e.g., the genes and related pathways involved with the induction of transgene expression by the cell line. The invention is particularly useful when there is little or no information about the genome of the cell line being studied, because it provides methods for identifying consensus sequences for known and previously undiscovered genes, and for designing oligonucleotide probes to the identified consensus sequences. Additionally, when the array is to be used to determine optimal conditions for expression of a transgene by the cell line, the invention teaches methods of including oligonucleotide probes to transgene sequences in the array. The invention also provides methods of using the array to identify genes and related pathways involved with the induction of a particular cell line phenotype. The invention also provides novel polynucleotides of undiscovered genes (i.e., a gene that had not been sequenced and/or shown to be expressed by CHO cells) and novel polynucleotides involved with the induction of a particular cell phenotype, e.g., increased survival when grown under stressful culture conditions, increased transgene expression, decreased production of an antigen, etc. These novel polynucleotides are termed novel CHO sequences and differential CHO sequences, respectively. The invention also provides genetically engineered expression vectors, host cells, and transgenic animals comprising the novel nucleic acid molecules of the invention. The invention additionally provides antisense and RNAi molecules to the nucleic acid molecules of the invention. The invention further provides methods of using the polynucleotides of the invention. | 02-04-2010 |
Gene W. Zdenek, Northridge, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090254071 | SYSTEM AND METHOD FOR IDENTIFYING A POSITION TO INSERT A SCLERAL PROSTHESIS INTO AN EYE - A method includes identifying an actual location of a ciliary body in a patient's eye. The method also includes identifying a position for a scleral prosthesis to be inserted into scleral tissue of the patient's eye based on the identified location of the ciliary body. The method could also include forming a scleral tunnel in the scleral tissue of the patient's eye based on the identified position and inserting the scleral prosthesis into the scleral tunnel. Identifying the actual location of the ciliary body could include illuminating a first portion of the patient's eye using illumination provided at a second portion of the patient's eye. The illumination provided at the second portion of the patient's eye may be provided through an eyelid of the patient and may travel under a cornea of the patient's eye to the first portion of the patient's eye. | 10-08-2009 |