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Gehrmann, DE

Bodo Gehrmann, Plettenberg DE

Patent application numberDescriptionPublished
20090047167Iron-Nickel Alloy - Disclosed is a creep-resistant low-expansion iron-nickel alloy that is provided with increased mechanical resistance and contains 40 to 43 wt. % of Ni, a maximum of 0.1 wt. % of C, 2.0 to 3.5 wt. % of Ti, 0.1 to 1.5 wt. % of Al, 0.1 to 1.0 wt. % of Nb, 0.005 to 0.8 wt. % of Mn, 0.005 to 0.6 wt. % of Si, a maximum of 0.5 wt. % of Co, the remainder being composed of Fe and production-related impurities. Said alloy has a mean coefficient of thermal expansion <5×10<−6>/K in the temperature range of 20 to 200 DEG C.02-19-2009
20100059145METAL FOIL - The invention relates to a metal foil having (in weight %) Ni 74-90%, W 10-26%, and Al and/or Mg and/or B contents of Al >0-max. 0.02%, Mg >0-max. 0.025%, B>0-max. 0.005%.03-11-2010
20100175847Iron-Nickel-Cobalt Alloy - Use of an iron-nickel-cobalt alloy in CFC mould construction comprising (in % by mass) Ni from 30 to 35%, Co from 3 to 6%, Al from 0.001 to 0.1%, Mn from 0.005 to 0.5%, Si from 0.005 to 0.5%, C max. 0.1%, balance Fe and constituents resulting from production, with the alloy having a mean coefficient of thermal expansion in the temperature range from 20 to 200 DEG C of <2.0 OE10<−6>/K.07-15-2010
20110056589IRON-NICKLE ALLOY - Disclosed is an iron-nickel alloy having the following composition, in % by mass: C 0.05 to 0.5%, Cr 0.2 to 2.0%, Ni 33 to 42%, Mn<0.1%, Si<0.1%, Mo 1.5 to 4.0%, Nb 0.01 to 0.5%, Al 0.1 to 0.8%, Mg 0.001 to 0.01%, V max. 0.1%, W 0.1 to 1.5%, Co max. 2.0%, the remainder Fe, and production-related impurities.03-10-2011

Patent applications by Bodo Gehrmann, Plettenberg DE

Mathias Gehrmann, Leverkusen DE

Patent application numberDescriptionPublished
20090069196Prediction of Breast Cancer Response to Chemotherapy - Method for the prediction of the response to epirubicin/cyclophosphamide-based chemotherapy of a breast cancer in a patient, from a tumour sample of said patient, comprising steps of determining the expression level of a group of marker genes consisting of (i) a first marker gene selected from the group consisting of MLPH, SPDEF, and AKR7A3; and (ii) a pair of second marker genes selected from the group of pairs consisting of (H2BFS and UBE2S), (BGN and ZBTB16), (ZBTB16 and EMP1), (LGALS8 and UBE2S) and (OLFML2B and ZBTB16); and (iii) a third marker gene selected from the group consisting of CYBA, ACP5, a gene specifically binding to Affymetrix probe set ID 210915 x at, LCK, GSTM3; classifying said sample as belonging to one of several breast cancer response classes from the expression levels determined; predicting the response of said breast cancer in said patient to chemotherapy from previously known characteristic properties of tumours of said one of several breast cancer response classes.03-12-2009
20090130678Methods and Kits for Breast Cancer Prognosis - The present invention relates to the field of prognosis of a proliferative disease in a patient. More specifically, the present invention relates to methods for the identification of the likely outcome of breast cancer in a breast cancer patient. The invention also relates to methods for the identification of the likely outcome of breast cancer in a patient on the basis of the ERBB2 status of the patient and expression levels of immune genes in tumour tissue of said patient.05-21-2009
20090222387Diagnosis, Prognosis and Prediction of Recurrence of Breat Cancer - The present invention relates to methods and compositions for the diagnosis, prognosis, and prediction of breast cancer. More specifically, the invention relates to classification of breast cancer tissue samples based on measuring the expression of a set of marker genes. The set is useful for the identification of clinically important breast cancer subtypes. Methods are disclosed for prediction, diagnosis and prognosis of breast cancer.09-03-2009
20090239223Prediction of Breast Cancer Response to Taxane-Based Chemotherapy - The invention relates to methods and kits for the prediction of a likely outcome of chemotherapy in a cancer patient. More specifically, the invention relates to the prediction of tumour response to chemotherapy based on measurements of expression levels of a small set of marker genes. The set of marker genes is useful for the identification of breast cancer subtypes responsive to taxane based chemotherapy, such as e.g. a taxane-anthracycline-cyclophosphamide-based (e.g. Taxotere (docetaxel)-Adriamycin (doxorubicin)-cyclophosphamide, i.e. (TAC)-based) chemotherapy.09-24-2009
20090311700Methods for Breast Cancer Prognosis - The present invention relates to methods, kits and systems for the prognosis of the disease outcome of breast cancer in untreated breast cancer patients. More specific, the present invention relates to the prognosis of breast cancer based on measurements of the expression levels of marker genes in tumor samples of breast cancer patients. Marker genes are disclosed which allow for an accurate prognosis of breast cancer in patients having node negative, fast proliferating breast cancer.12-17-2009
20110143946Method for predicting the response of a tumor in a patient suffering from or at risk of developing recurrent gynecologic cancer towards a chemotherapeutic agent - The present invention relates to a method for predicting a response of a tumor in a patient suffering from or at risk of developing recurrent gynecologic cancer towards a chemotherapeutic agent, said method comprising the steps of: a) obtaining a biological sample from said patient; b) determining the pattern of expression level of at least one gene of the group comprising AKR1C1, MLPH, ESR1, PGR, COMP, DCN, IGKC, CCL5, FBN1 and/or UBE2C, or of genes coregulated therewith, in said sample; c) comparing the pattern of expression levels determined in (b) with one or several reference pattern (s) of expression levels; d) identifying at least one marker gene; e) determining a molecular subtype for said sample on the basis of (d); and f) predicting from said molecular subtype response of a tumor for a chemotherapeutic agent, wherein the molecular subtype is selected from the group comprising the subtypes basal, stromal-high, stromal-low, luminal A, immune system-high, immune system-low, proliferation-high and/or proliferation-low.06-16-2011
20110166838ALGORITHMS FOR OUTCOME PREDICTION IN PATIENTS WITH NODE-POSITIVE CHEMOTHERAPY-TREATED BREAST CANCER - The invention relates to methods for predicting an outcome of cancer in a patient suffering from cancer, said patient having been previously diagnosed as node positive and treated with cytotoxic chemotherapy, said method comprising determining in a biological sample from said patient an expression level of a plurality of genes selected from the group consisting of ACTG1, CAl2, CALM2, CCND1, CHPT1, CLEC2B, CTSB, CXCL13, DCN, DHRS2, EIF4B, ERBB2, ESR1, FBXO28, GABRP, GAPDH, H2AFZ, IGFBP3, IGHG1, IGKC, KCTD3, KIAA0101, KRT17, MLPH, MMP1, NAT1, NEK2, NR2F2, OAZ1, PCNA, PDLIM5, PGR, PPIA, PRC1, RACGAP1, RPL37A, SOX4, TOP2A, UBE2C and VEGF; ABCB1, ABCG2, ADAM15, AKR1C1, AKR1C3, AKT1, BANF1, BCL2, BIRC5, BRMS1, CASP10, CCNE2, CENPJ, CHPT1, EGFR, CTTN, ERBB3, ERBB4, FBLN1, FIP1L1, FLT1, FLT4, FNTA, GATA3, GSTP1, Herstatin, IGF1R, IGHM, KDR, KIT, CKRT5, SLC39A6, MAPK3, MAPT, MKI67, MMP7, MTA1, FRAP1, MUC1, MYC, NCOA3, NFIB, OLFM1, TP53, PCNA, PI3K, PPERLD1, RAB31, RAD54B, RAF1, SCUBE2, STAU, TINF2, TMSL8, VGLL1, TRA@, TUBA1, TUBB, TUBB2A.07-07-2011

Patent applications by Mathias Gehrmann, Leverkusen DE

Volker Gehrmann, Erlangen DE

Patent application numberDescriptionPublished
20080238657Method for Monitoring a Group of Objects and Associated Arrangement - A method for monitoring a group of objects, and an arrangement to implement the method includes providing each object of the group to be monitored with a radio node of a self-networking radio network, whereby each radio node within the group has a unique identification. The radio nodes of the group automatically reveal themselves at a starting time and network with one another. The radio nodes of the group monitor themselves from the starting time and convey at least one specified change in an initial mutual situation. At least one of the radio nodes when notifying or recognizing a specified change, conveys information concerning the change to a monitoring unit and/or controls an alarm transmitter for activating an alarm.10-02-2008
20090213785System and Method for the Monitoring of Grouped Objects - A system and a method for monitoring grouped objects with a gateway and a plurality of radio nodes attachable to the objects. Each radio node has a computing unit, a short-range communications unit and an energy supply unit. One of the radio nodes or the gateway has a localization unit. Optionally, one of the radio nodes also has a long-range communications unit. The computing unit contains a control program for the processing of predetermined tasks in radio nodes, which is designed for the control of bi-directional communications between the radio nodes via the short-range communications unit for the formation of an ad hoc network. The control program undertakes the control of a tuning process between the radio nodes and selects one of the radio nodes for the processing of one of the predetermined tasks, the selected node at that instant being best suited for the task according to predetermined criteria.08-27-2009
20100184457DEVICE FOR DETERMINING A DEVICE POSITION - A device for determining a device position, which includes a receiver for receiving signals of a plurality of transmitters and a determiner for determining reception powers of the signals of the plurality of transmitters. The device further includes a provider for providing transmitter positions of the transmitters on the basis of the signals of the plurality of transmitters. The device further includes a determiner for determining a first position of the device on the basis of the transmitter positions, wherein the determiner for determining the first position is further formed to determine transmitter directions on the basis of the first position and the transmitter positions, and to determine a second position of the device on the basis of the transmitter directions, the transmitter positions and the reception powers.07-22-2010

Patent applications by Volker Gehrmann, Erlangen DE