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Garcia, FR
Alexandre Garcia, Ivry Sur Seine FR
| Patent application number | Description | Published |
|---|---|---|
| 20100310800 | PROCESS FOR PREPARING A METALLIZED SUBSTRATE, SAID SUBSTRATE AND USES THEREOF - The present invention relates to a process for preparing a metallized substrate, comprising the steps consisting in: grafting onto said substrate a compound of polymer type optionally bearing a group that is capable of chelating at least one metal ion; placing said compound of polymer type that is capable of chelating at least one metal ion in contact with at least one metal ion, and subjecting the compound of polymer type to conditions for reducing said chelated metal ion(s), and repeating the chelation/reduction steps until a metallized substrate is obtained. The present invention also relates to the substrate obtained during this process and to the uses thereof. | 12-09-2010 |
| 20100323119 | PROCESS FOR THE PREPARATION OF AN ORGANIC FILM AT THE SURFACE OF A SOLID SUPPORT WITH OXIDIZING TREATMENT - The present invention relates to a process for the preparation of an organic film on a portion of the surface of a solid support made of (co)polymer, characterized in that it comprises the successive steps consisting in (i) subjecting said surface portion to an oxidizing treatment and (ii) grafting an organic film to said surface portion by radical chemical grafting. | 12-23-2010 |
Alphonse Garcia, Montrouge FR
| Patent application number | Description | Published |
|---|---|---|
| 20110269674 | SYNTHETIC OR NATURAL PEPTIDES BINDING PROTEIN PHOSPHATASE 2A, IDENTIFICATION METHOD AND USES - The present invention relates to novel synthetic or natural peptides for use in treating viral or parasitic infections or in the treatment of tumors. The peptides of the present invention are less than 30 amino acids in size, preferably less than 20 amino acids, in particular 15 to 20 amino acids, and in vitro the peptides specifically bind a type 2A protein phosphatase holoenzyme or one of its subunits. The invention also relates to a method for identifying said peptides, and to their uses. | 11-03-2011 |
| 20120021999 | PRO-APOPTOTIC PEPTIDES - The invention relates to chimeric peptides useful as pro-apoptotic agents, for inhibition of in vitro cell proliferation and for treatment of tumors. | 01-26-2012 |
Alphonse Garcia, Paris FR
| Patent application number | Description | Published |
|---|---|---|
| 20100009909 | PEPTIDES BINDING THE PHOSPHATASE 2A PROTEIN - The invention relates to novel synthetic or natural E4orf4 or Bcl-2 peptides particularly useful in antitumoral, antiviral and antiparasitic treatments, said peptides being less than 30 amino acids long and binding in vitro to a phosphatase 2A protein holoenzyme or one of its subunits. The invention also relates to polynucleotides encoding the novel peptides, vectors expressing same, as well as antibodies identifying same and probes identifying transcripts thereof. | 01-14-2010 |
| 20110028387 | METHODS OF SCREENING OF PP1-INTERACTING POLYPEPTIDES OR PROTEINS, PEPTIDES INHIBITING PP1c BINDING TO Bcl-2 PROTEINS, BCL-XL AND BCL-W, AND USES THEREOF - The invention relates to methods for identifying novel PP1-interacting polypeptides and proteins, compounds which are able to inhibit the binding of PP1c to certain factors naturally interacting with it, especially proteins of the Bcl-2 family (such as Bcl-x | 02-03-2011 |
Christine Garcia, Castres FR
| Patent application number | Description | Published |
|---|---|---|
| 20080200534 | Cosmetic and Pharmaceutical Compositions Comprising Lauroyl Proline and an Ester of Anhydrohexitol and of an Aliphatic Carboxylic Acid - Composition (A) containing, for 100% of its mass: from 10 mass % to 90 mass % of N-lauroyl proline (I) and from 10 mass % to 90 mass % of an ester (II) of anhydrohexitol and of a saturated or unsaturated, linear or branched aliphatic carboxylic acid containing from 12 to 20 carbon atoms optionally substituted with one or more hydroxyl groups, or of a mixture of esters (II); use thereof for preparing a medicament with lipolytic activity, intended to induce slimming of the human or animal body and/or the reduction of cellulite or of the orange-feel appearance; cosmetic formulation or therapeutic composition containing same; process for the preparation thereof and process for the solubilization of N-lauroyl proline (I) in a liquid medium. | 08-21-2008 |
| 20090175811 | USE OF COMPOUND THAT INACTIVATES PROTEIN KINASE A IN A COMPOSITION CONTAINING A COSMETICALLY ACCEPTABLE MEDIUM FOR LIGHTENING THE SKIN - A method of using a compound to lighten the skin by inactivating protein kinase A. The compound may be in a composition with either a pharmacologically or cosmetically acceptable medium. Depending upon the medium and concentration of the compound, the composition may be used either therapeutically or non-therapeutically. | 07-09-2009 |
| 20100061945 | Use Of Quinoa Extract As Cosmetic And Pharmaceutic Slimming Agent And/Or As An Agent Preventing The Formation Of New Fats In The Human Body - The invention relates to the use of Quinoa extract as a slimming agent and/or as an agent preventing the formation of new fats in the body, in a composition comprising a cosmetically acceptable medium. The invention relates to a non-therapeutic treatment method using said extract and to the use of said extract for preparing a drug with lipolytic activity for inducing a slimming effect on the human body and for preparing a drug for preventing the formation of new fats in the human body. | 03-11-2010 |
| 20110144316 | METHOD FOR RESTRUCTURING THE EPIDERMIS USING A POLYOL-GLYCOSIDE COMPOSITION - A method for restructuring the epidermis with a composition, wherein said composition includes a polyol-glycoside and said polyol-glycoside is obtained by the acetalization of a polyol with a reducing sugar. | 06-16-2011 |
Christophe Garcia, Les Issards FR
| Patent application number | Description | Published |
|---|---|---|
| 20100078510 | WASTE COMMINUTING DEVICE - A waste comminuting device includes a comminuting housing ( | 04-01-2010 |
Christophe Garcia, Rennes FR
| Patent application number | Description | Published |
|---|---|---|
| 20080201282 | System and Method for Locating Points of Interest in an Object Image Implementing a Neural Network - A system is provided for locating at least two points of interest in an object image. One such system uses an artificial neural network and has a layered architecture having: an input layer, which receives the object image; at least one intermediate layer, known as the first intermediate layer, consisting of a plurality of neurons that can be used to generate at least two saliency maps, which are each associated with a different pre-defined point of interest in the object image; and at least one output layer, which contains the aforementioned saliency maps. The maps include a plurality of neurons, which are each connected to all of the neurons in the first intermediate layer. The points of interest are located in the object image by the position of a unique global maximum on each of the saliency maps. | 08-21-2008 |
| 20080279424 | Method of Identifying Faces from Face Images and Corresponding Device and Computer Program - A method identifying faces from facial images called query images, associated with at least one person, including a learning phase using learning images and a recognition phase used to identify the faces appearing in query images. The learning phase includes filtering the images, applied on the basis of a group of at least two learning facial images associated with the at least one person, enabling selection of at least one learning image representing the face to be identified. The recognition phase uses only the learning images selected during the learning phase. Filtering is performed using at least one of the thresholds belonging to the group including: a maximum distance taking at least account of the membership of the vectors in a cloud constituted by the vectors; and a maximum distance between the vectors and vectors rebuilt after projection of the vectors on a space associated with said cloud of vectors. | 11-13-2008 |
Daniel Alvarez Garcia, Bobigny Cedex FR
| Patent application number | Description | Published |
|---|---|---|
| 20090021953 | LIGHTING AND/OR INDICATING SYSTEM FOR A VEHICLE, WITH IMPROVED ACTUATOR CONTROL - The lighting and/or signaling system according to the invention comprises at least one lighting and/or signaling device which is able to emit at least one light beam and is equipped with at least one actuator for adjusting an angle of the light beam, and at least one actuator control device for controlling the actuator. According to the invention, the actuator control device transmits an active setpoint information item to the actuator only when a current value of the setpoint information item differs substantially from a previous value of the setpoint information item. The improved actuator control incorporated in the system according to the invention helps to achieve greater reliability and a longer service life. | 01-22-2009 |
Denis Garcia, Montbazin FR
| Patent application number | Description | Published |
|---|---|---|
| 20090305019 | CONCRETE COMPOSITION WITH REDUCED SHRINKAGE - A concrete composition includes: a hydraulic binder component which includes cement, particulate materials having a size of less than 200 μm, and an expansive agent; granular materials having a size (D50) greater than 200 μm; a shrinkage reducing agent; a superplasticizer; and water; wherein the water to hydraulic binder ratio is from 0.1 to 0.5 by weight, the shrinkage reducing agent is present at 0.1 to 1.0% by weight of binder, and the particulate materials are present in a concentration of from 10 to 80% by total weight of binder. | 12-10-2009 |
Emmanuel Garcia, Saint-Didier De La Tour FR
| Patent application number | Description | Published |
|---|---|---|
| 20090301354 | Method For Compacting A Hydraulic Binder And Novel Milled Pellets - A method of compressing a composition includes compacting a hydraulic binder in a quantity greater than 95% by weight and a disintegrating agent in a quantity less than or equal to 0.5% by weight, into compacts in a roller press. The milled pellet of a composition including a hydraulic binder in a quantity greater than 95% by weight and a disintegrating agent in a quantity less than or equal to 0.5% by weight. | 12-10-2009 |
| 20100294171 | CONCRETE WITH A LOW CLINKER CONTENT - A process for the preparation of a wet concrete composition, including a stage of mixing of: Portland clinker in the form of grains having a Dv97 from 10 to 30 μm or having a Blaine specific surface greater than or equal to 5300 cm | 11-25-2010 |
Eric Garcia, Paris FR
| Patent application number | Description | Published |
|---|---|---|
| 20120022292 | METHOD FOR PREPARING EPLIVANSERIN HEMIFUMARATE - Method for preparing eplivanserin hemifumarate. | 01-26-2012 |
Eric Garcia, Uffholtz FR
| Patent application number | Description | Published |
|---|---|---|
| 20090304795 | TABLETS WITH IMPROVED DRUG SUBSTANCE DISPERSIBILITY - The present invention relates to a method for the preparation of pharmaceutical compositions in the form of tablets with improved drug substance dispersibility, which method comprises | 12-10-2009 |
Florent Garcia, Lans En Vercors FR
| Patent application number | Description | Published |
|---|---|---|
| 20110262211 | KNUCKLE PROTECTOR FOR A VEHICLE - The invention relates to a protection device ( | 10-27-2011 |
Florent Garcia, Fuveau FR
| Patent application number | Description | Published |
|---|---|---|
| 20100085091 | PROPORTIONAL PHASE COMPARATOR AND METHOD FOR PHASE-ALIGNING DIGITAL SIGNALS - Embodiments of a proportional phase comparator and method for aligning digital signals are generally described herein. In some embodiments, circuitry to align digital signals comprises a proportional phase comparator that generates triangular-shaped pulses for application to a charge pump. The triangular-shaped pulses may reduce an amount of charge injection in the charge pump close to convergence. | 04-08-2010 |
| 20110115560 | DIFFERENTIAL PAIR WITH CONSTANT OFFSET - A bias current is generated for an unbalanced differential pair that is proportional to the transconductance gain of the differential pair. When the transconductance gain varies (e.g., due to temperature variations), the bias current varies in proportion thereby maintaining a constant offset voltage. In some implementations, a voltage to current converter circuit generates the bias current from a constant reference voltage that is independent of temperature and voltage supply variations (e.g., a bandgap reference voltage). | 05-19-2011 |
Gérard Garcia, Saint Laurent Du Var FR
| Patent application number | Description | Published |
|---|---|---|
| 20090293844 | Pressure-controlling electromagnetic valve for distinct electromagnetic and hydraulic units - The pressure controlling electromagnetic valve comprises an electric sub-assembly ( | 12-03-2009 |
Guillermo Garcia, Bossey FR
| Patent application number | Description | Published |
|---|---|---|
| 20100200447 | Dispensing Value Sheet Store - A store for storing value sheets such as banknotes in a stack and for dispensing the value notes from the stack. When more than a single value sheet is dispensed from the stack, the store returns all but one of the value sheets to the stack while moving the stack to reduce friction between the returning value sheet and the topmost value sheet of the stack. Means for securing the stack are also provided: a support for the stack is anchored and/or extra pressure is applied to the stack. The store includes means for indicating when the stack contains more than a predetermined number of value sheets and means for preventing securing of the store when the predetermined number of value sheets is exceeded. A value sheet store with part of a sidewall integrally formed with the lid. A value sheet store which includes a lid attached to a housing by a hinge located on an edge of the housing. Apparatus and a method for determining the height of a stack of value sheets. A shutter arrangement in a value sheet store which acts to block an aperture through which value sheets are dispensed. | 08-12-2010 |
| 20100207316 | Dispensing Value Sheet Store - A store for storing value sheets such as banknotes in a stack and for dispensing the value notes from the stack. When more than a single value sheet is dispensed from the stack, the store returns all but one of the value sheets to the stack while moving the stack to reduce friction between the returning value sheet and the topmost value sheet of the stack. Means for securing the stack are also provided: a support for the stack is anchored and/or extra pressure is applied to the stack. The store includes means for indicating when the stack contains more than a predetermined number of value sheets and means for preventing securing of the store when the predetermined number of value sheets is exceeded. A value sheet store with part of a sidewall integrally formed with the lid. A value sheet store which includes a lid attached to a housing by a hinge located on an edge of the housing. Apparatus and a method for determining the height of a stack of value sheets. A shutter arrangement in a value sheet store which acts to block an aperture through which value sheets are dispensed. | 08-19-2010 |
Jean-Luc Garcia, Courcouronnes FR
| Patent application number | Description | Published |
|---|---|---|
| 20090085701 | PROVIDING AN INDUCTIVE COUPLER ASSEMBLY HAVING DISCRETE FERROMAGNETIC SEGMENTS - An inductive coupler assembly has a first coupler having a first support structure and plural discrete first ferromagnetic segments supported by the first support structure, and a second coupler to inductively couple to the first coupler, the second coupler having a second support structure and plural discrete ferromagnetic segments supported by the second support structure. | 04-02-2009 |
| 20100006303 | SHAPE MEMORY MATERIAL SEALS - The invention relates to a shape memory sleeve to create an annular tightness. More precisely, the invention relates to a ring to provide tightness, made from shape memory alloy material and including an interior annular portion and an exterior annular portion, comprising at least one annular groove or one annular rib on its interior annular portion. | 01-14-2010 |
| 20110260715 | VALVE POSITION SENSOR - A valve position sensor of a sliding sleeve of a flow control valve comprising a sleeve displacement converting means for converting a sleeve displacement into a radial displacement, and a measuring means for detecting the radial displacement and correlating the radial displacement to the position of the sliding sleeve within the flow control valve. | 10-27-2011 |
Jean-Luc Garcia, Issy Les Moulineaux FR
| Patent application number | Description | Published |
|---|---|---|
| 20100183067 | POST-PROCESSING FOR REDUCING QUANTIZATION NOISE OF AN ENCODER DURING DECODING - The invention relates to the processing of a signal that is compression encoded (COD) according to a predetermined encoding type applying a quantification operation (Q) and then decoded (DEC) so that the quantification noise is present in the decoded signal (S*). The signal processing of the invention comprises applying a quantification noise reduction (TBQ) to the decoded signal (S), preferably in the following manner: first obtaining information (INF) on the type of compression encoding, selecting a model for the reduction of the quantification noise adapted to said information by estimating the quantification noise (BQ) that the encoding may have generated; and applying to the decoded signal (S*) a processing for reducing the quantification noise (FIL) according to the selected model. | 07-22-2010 |
Jean-Marie Garcia, Toulouse FR
| Patent application number | Description | Published |
|---|---|---|
| 20100195510 | Method for the Digital Evaluation of a Data Transmission Network - The invention relates to a method for the digital evaluation of a data transmission network comprising a plurality of nodes ( | 08-05-2010 |
Jean-Pierre Garcia, Colomiers FR
| Patent application number | Description | Published |
|---|---|---|
| 20080201025 | Method of Distributing Braking Within at Least One Group of Brakes of an Aircraft - The invention provides a method of managing the braking of an aircraft having a plurality of brakes comprising friction elements, the method comprising the following steps for at least one group ( | 08-21-2008 |
| 20090210126 | METHOD OF DISTRIBUTING BRAKING BETWEEN THE BRAKES OF AN AIRCRAFT - A method of distribution braking between the brakes of an aircraft. The method includes a first step of estimating a braking force objective and a steering torque objective to be achieved by the brakes of the aircraft. It also includes the steps of defining at least two groups of brakes ( | 08-20-2009 |
Jonathan Garcia, Monestier Du Percy FR
| Patent application number | Description | Published |
|---|---|---|
| 20090162657 | METHOD FOR MANUFACTURING METAL CHIPS BY PLASMA FROM A LAYER COMPRISING SEVERAL ELEMENTS - The invention relates to a method for manufacturing chips composed of at least one electrically conductive material. Such a method comprises the following steps: | 06-25-2009 |
Justo Garcia, Courbevoie FR
| Patent application number | Description | Published |
|---|---|---|
| 20090304137 | Package Serving to Accommodate a Case Containing Radioactive - The invention concerns a cask ( | 12-10-2009 |
Laurent Jean Garcia, Saint Martin D'Heres FR
| Patent application number | Description | Published |
|---|---|---|
| 20100097093 | INPUT/OUTPUT CIRCUITRY WITH COMPENSATION BLOCK - Circuitry including an output circuit having a first variable resistance block coupled between a first supply voltage and an output node, the first variable resistance block having a plurality of selectable resistive elements coupled in series with at least one resistor between the first supply voltage and the output node, the output circuit having an output impedance determined by the resistance of the first variable resistance block; and a compensation circuit for regulating the impedance of the first variable resistance block of the output circuit, the compensation circuit having a second variable resistance block coupled between the first supply voltage and the first node of an external resistor, the second node of the external resistor being coupled to a second supply voltage, wherein the second variable resistance block comprises a plurality of selectable resistive elements coupled in series with at least one resistor between the first supply voltage and the first node of the external resistor, and wherein the plurality of selectable resistive elements of the first and second variable resistance blocks are selected based on a voltage level at the first node of the external resistor. | 04-22-2010 |
Luc Garcia, Saint Paul De Varces FR
| Patent application number | Description | Published |
|---|---|---|
| 20090322580 | ANALOG FILTER WITH PASSIVE COMPONENTS FOR DISCRETE TIME SIGNALS - A filter intended to receive a discrete time signal at a sampling dock frequency, comprising a determined number, greater than 2, of filtering units, each filtering unit comprising head capacitors in a number equal to the determined number, assembled in parallel between an input terminal and the terminal of an integration capacitor; and means for connecting, in successive clock cycles in a number equal to the determined number, successively each head capacitor to the input terminal, and for then simultaneously connecting the head capacitors to the integration capacitor, and in which the successive dock cycles during which the head capacitors of a filtering unit are connected to the input terminal are offset by one dock cycle from one filtering unit to the next one. | 12-31-2009 |
Luis Garcia, Saint Denis FR
| Patent application number | Description | Published |
|---|---|---|
| 20120077860 | Adeno-Associated Viral Vector for Exon Skipping in a Gene Encoding a Dispensable Domain Protein - The invention concerns an adeno-associated viral vector comprising: | 03-29-2012 |
Marcel Garcia, Montpellier Cedex FR
| Patent application number | Description | Published |
|---|---|---|
| 20120093795 | COMPOUNDS TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR - The invention relates to conjugates of products of interest and of compounds targeting the cation-independent mannose 6-phosphate receptor with a high affinity. The invention also relates to their applications, for instance in enzyme replacement therapies. | 04-19-2012 |
Marcel Garcia, Prades-Le-Lez FR
| Patent application number | Description | Published |
|---|---|---|
| 20110262357 | Metalloporphyrin Derivatives, Nanoparticles Comprising the Same, and Use Thereof for Photodynamic Therapy - Nanovectors are disclosed that make it possible to simultaneously target, image, and treat cancerous cells using photodynamic therapy. Also disclosed are novel molecules (I) derived from porphyrins, silica-based nanoparticles comprising the same, and their use in photodynamic therapy. | 10-27-2011 |
Michel Garcia, Lauris FR
| Patent application number | Description | Published |
|---|---|---|
| 20100196298 | Coloring Materials And Their Use In Compositions, In Particular Cosmetic Compositions - The invention relates to a coloring material comprising a colored product bound to a solid substrate in which said colored product is a colored derivative of geniposide and/or genipin and/or geniposidic acid and/or an extract of a plant comprising at least one of the abovementioned products and said solid substrate is based on silicate and includes at least one metal cation. It also relates to a process for preparing this coloring material. It also relates to the use of this coloring material in the preparation of a coloring composition, in particular of a cosmetic composition, and to a method for making up the skin or superficial body growths. | 08-05-2010 |
| 20110223121 | DYESTUFFS OF PLANT ORIGIN AND USE THEREOF FOR COLOURING COMPOSITIONS, IN PARTICULAR COSMETIC COMPOSITIONS - Dyestuff of plant origin is obtained from a colored part of a plant species, the cell tissues of which contain iridisomes responsible for the coloration of said part. Most particularly, a blue dyestuff is obtained from the arils of the seeds of the plant species | 09-15-2011 |
Nicolas Garcia, Paris FR
| Patent application number | Description | Published |
|---|---|---|
| 20090139193 | WALL-FLOW HONEYCOMB FILTER HAVING HIGH STORAGE CAPACITY AND LOW BACKPRESSURE - A wall-flow honeycomb filter comprising a ceramic monolith having a plurality of porous walls formed therein. The plurality of porous walls define a plurality of inlet cells and a plurality of outlet cells extending between an inlet end face and an outlet end face of the monolith. The inlet cells are open at the inlet end face and plugged at or near the outlet end face. The outlet cells are open at the outlet end face and plugged at or near the inlet end face. The monolith has a ratio of a combined cross-sectional area of the inlet cells to a combined cross-sectional area of the outlet cells greater than 1. The monolith has at least one inlet cell cluster which contains an N×M group of inlet cells, N and M being integers greater than 1, each inlet cell cluster consisting of a plurality of inlet cells separated by inlet cluster walls. | 06-04-2009 |
Patrice Garcia, Crolles FR
| Patent application number | Description | Published |
|---|---|---|
| 20100069031 | MIXER-AMPLIFIER FOR AN RF RECEIVE CHAIN - A mixer-amplifier of an RF signal including at least an amplifier circuit and a mixing circuit controlled at a local oscillator frequency, for amplifying a signal applied on at least one input terminal and converting a first frequency of this signal into a second, lower, frequency, and including a reverse feedback loop switched at the local oscillator frequency. | 03-18-2010 |
Philippe Garcia, Bussieres FR
| Patent application number | Description | Published |
|---|---|---|
| 20100099057 | ROOT CANAL INSTRUMENT HANDLE MADE OF TWO CO-AXIAL PORTIONS JOINED IN AXIAL TRANSLATION AND IN ROTATION - The invention relates to a method for designing and producing a package intended for the protection and/or transportation of a product. All of the digital design steps for the package are integrated in the method for digitizing the product, which includes a step of laminating a virtual key form of the product used to define geometrical data of each layer of the package to be cut. Then, the cutting is carried out followed by the stacking of the layers of the package defined by the design steps for said package to form a real package. The invention also relates to the package obtained by the method. | 04-22-2010 |
Pierre Garcia, Juillan FR
| Patent application number | Description | Published |
|---|---|---|
| 20110281862 | ALFA-CARBOLINE INHIBITORS OF NPM-ALK, RET, AND BCR-ABL - The present invention relates to compounds of formula (I) | 11-17-2011 |
Stephane Garcia, La Gaude FR
| Patent application number | Description | Published |
|---|---|---|
| 20120087582 | METHOD AND SYSTEM FOR RESIZING AN IMAGE - There is disclosed a method and system for resizing a digital image wherein a RGB image is converted into an YCbCr image (Y, Cb, Cr planes). Thereafter, a discrete cosine transform (DCT), followed by a specific inverse cosine transform (IDCT) is performed on each row/column of the Y, Cb, Cr planes. The mentioned specific operation corresponds to a type of homothetic matrix, which dimensions are defined by a scaling factor. In order to produce a scaled image, the scaled Y, Cb, Cr images are transformed to an RGB image for display. | 04-12-2012 |
Sylvie Garcia, Cachan FR
| Patent application number | Description | Published |
|---|---|---|
| 20100011450 | IMMUNODEFICIENT MICE TRANSGENIC FOR HLA CLASS I AND HLA CLASS II MOLECULES AND THEIR USES - The invention relates to mice which are genetically deprived of T, B lymphocytes and NK cells, deficient for murine MHC class I and/or MHC class II molecules, and transgenic for the expression of the HLA class I and/or HLA class II molecules, and to their use as recipient hosts for the transplantation of human haematopoietic precursors, to study the human adaptative immune system development and function in vivo. The invention relates also to the applications of this human/mouse chimera model to improve immunotherapy against pathogens, cancer and autoimmune diseases. | 01-14-2010 |
| 20100138938 | METHOD OF PRODUCING A MULTICHIMERIC MOUSE AND APPLICATIONS TO STUDY THE IMMUNOPATHOGENESIS OF HUMAN TISSUE-SPECIFIC PATHOLOGIES - The invention relates to a method of producing a multichimeric mouse comprising a functional xenogenic (human) immune system restricted to the MHC class I and/or class II molecules (HLA molecules) of the xenogenic species solely, and a functional tissue. The invention relates also th the use of the multichimeric mouse obtainable by said method, to study the immunopathogenesis of tissue-specific diseases (infectious, tumoral or auto-immune pathologies) and to their applications to design and test vaccines or immunotherapeutic agents against these pathologies. | 06-03-2010 |
Thierry Garcia, Rambouillet FR
| Patent application number | Description | Published |
|---|---|---|
| 20080223810 | Multipurpose Lid, Especially for Liquids, Including Paint Cans - The invention concerns a lid ( | 09-18-2008 |
| 20100175607 | Floating Aquatic Platform Structure - The invention concerns a floating aquatic platform structure including a transparent base, capable of accommodating pieces of furniture and people, and the means to keep it upright within an area of natural or man-made water. The aquatic platform is designed in the form of a rigid set of self-supporting frames ( | 07-15-2010 |
Valerie Garcia, Margny-Les-Compiegne FR
| Patent application number | Description | Published |
|---|---|---|
| 20100274035 | Process for Recycling Cyclopentadienyl Derivatives and Preparing Metallocenes From Recycled, Substituted Cyclopentadienyl Derivatives - The present invention relates to a process for recycling cyclopentadienyl derivatives of the formulae (I) and (I′), a process for preparing metallocenes of the formula (III) from cyclopentadienyl derivatives of the formulae (I) and (I′) or from bridged biscyclopentadienyl derivatives of the formula (II), in which the cyclopentadienyl derivatives of the formulae (I), (I′) or (II) which are used have been at least partly recovered and purified by means of liquid-solid chromatography, and the use of liquid-solid chromatography for purifying substituted, recovered cyclopentadienyl derivatives of the formulae (I), (I′) or (II). | 10-28-2010 |
Valerie Garcia, Compiegne FR
| Patent application number | Description | Published |
|---|---|---|
| 20080200708 | Preparation of Partially Hydrogenated Rac-Ansa-Metallocene Complexes - The invention relates to a process for preparing hydrogenated or partially hydrogenated, racemic ansa-metallocene complexes by reacting bridged or unbridged transition metal complexes with alkali metal compounds or alkaline earth metal compounds, heating the resulting reaction mixture to a temperature in the range from −78 to 250° C. and at least partially hydrogenating the reaction products in the presence of a suitable catalyst, to the corresponding hydrogenated or partially hydrogenated metallocenes and to their use as catalysts or as a constituent of catalysts for the polymerization of olefinically unsaturated compounds or as reagents or catalysts in stereoselective synthesis. | 08-21-2008 |
| 20080275261 | Process for the Racemoselective Preparation of Ansa-Metallocenes - The present invention relates to a process for the racemoselective preparation of ansa-metallocene complexes of the formula (I) | 11-06-2008 |