| Patent application number | Description | Published |
|---|
| 20080207553 | Biodegradable Cationic Polymers - Polymers comprising a polyethylenimine, a biodegradable group, and a relatively hydrophobic group are useful for the delivery of bioactive agents to cells. | 08-28-2008 |
| 20080253969 | MULTI-FUNCTIONAL POLYGLUTAMATE DRUG CARRIERS - Various biodegradable polyglutamate polymer conjugates that can include recurring units of the general formulae (I) and (II) are described herein. Such polymer conjugates are useful for variety of drug, targeting, stabilizing and/or imaging agent delivery applications. | 10-16-2008 |
| 20080279777 | COMPOSITIONS THAT INCLUDE A HYDROPHOBIC COMPOUND AND A POLYAMINO ACID CONJUGATE - Various compositions that include a hydrophobic compound and a polyamino acid conjugate are prepared. The compositions described herein are useful for a variety of drug, biomolecule, and imaging agent delivery applications. | 11-13-2008 |
| 20080279778 | POLYGLUTAMATE CONJUGATES AND POLYGLUTAMATE-AMINO ACID CONJUGATES HAVING A PLURALITY OF DRUGS - Various biodegradable polyglutamate conjugates comprising recurring units of the general formulae (I), (II), (III), (IV), (V), and/or (VI) are prepared. The polymers are conjugated with a plurality of drugs. Such polymer conjugates are useful for variety of drug, targeting, stabilizing and/or imaging agent delivery applications. | 11-13-2008 |
| 20080279782 | POLYMERS CONJUGATED WITH PLATINUM DRUGS - Various biocompatible polymers having platinum compounds conjugated thereto are prepared. Such polymers are useful for a variety of drug, biomolecule, and imaging agent delivery applications. Also disclosed are methods of using the polymers to treat, diagnose, and/or image a subject. | 11-13-2008 |
| 20080312174 | WATER SOLUBLE CROSSLINKED POLYMERS - Compositions for siRNA delivery are described which include water soluble degradable crosslinked cationic polymers having a water soluble polyethylene glycol component, a cationic polyethyleneimine component and a degradable unit component. The composition may be used to deliver siRNA to cells, particularly cancer cells. The composition may be applied to a solid surface such as a multiwell plate so that the delivery of siRNA may be carried out on the solid surface. | 12-18-2008 |
| 20090105179 | DRUG CARRIERS - Compositions that can include a cationic polymeric carrier, targeting agent, and therapeutic agent are disclosed herein. The therapeutic agent may have a therapeutic activity such as inhibiting fibrosis within a target organ or tissue or inhibiting the growth of a cancer cell. | 04-23-2009 |
| 20100028416 | DRUG CARRIERS - Compositions that can include a carrier, targeting agent, and therapeutic agent are disclosed herein. The therapeutic agent may have a therapeutic activity such as inhibiting fibrosis within a target organ or tissue or inhibiting the growth of a cancer cell. | 02-04-2010 |
| 20100093935 | METHOD OF PREPARING POLYGLUTAMATE CONJUGATES - Methods for preparing and isolating polymer conjugates that include a recurring unit of Formulae (I) and (Ia) are described herein. The polymer conjugates can include an anti-cancer drug. | 04-15-2010 |
| 20100160210 | GUANIDINIUM DELIVERY CARRIERS - Disclosed herein are transmembrane transporter compounds containing guanidinium groups. Also disclosed herein are methods for transporting a biologically active moiety across a biological membrane using the transmembrane transporter compounds. Particularly, this invention provides a method for the delivery of a biologically active moiety across the biological membranes of such membranes as endothelial tissues. | 06-24-2010 |
| 20100160239 | PEPTIDE NUCLEIC ACID BASED GUANIDINIUM COMPOUNDS - Disclosed herein are transmembrane transporter compounds containing guanidinium groups to enhance transport across biomembranes. Therapeutic and other biologically active moieties may be attached to the compounds. The transmembrane transporter compounds may include peptide nucleic acid monomer units. | 06-24-2010 |
| 20100210715 | BIODEGRADABLE CATIONIC POLYMERS - Polymers comprising a polyethylenimine, a biodegradable group, and a relatively hydrophobic group are useful for the delivery of bioactive agents to cells. | 08-19-2010 |
