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| 20090105732 | Mechanical apparatus and method for delivering materials into the inter-vertebral body space for nucleus replacement - The present invention relates to a device and method to perform 1) disk fusing, 2) an artificial replacement of the nucleus, 3) artificial replacement of the annulus, or 4), an artificial replacement of both the nucleus and annulus. The device is designed to be placed into the inter-vertebral space following discectomy. The invention includes a delivery catheter and an expandable continuous mesh that has a torus configuration with a lumen within the mesh and a center hole. The mesh can be diametrically expanded in diameter into the disc space whereby various materials can be injected into the lumen and/or the center hole. | 04-23-2009 |
| 20100160947 | SYSTEMS AND METHODS FOR DILATION AND DISSECTION OF TISSUES - A minimally invasive dilation device includes a stylus, a plurality of rigid arms radially arrayed about the stylus, and a dilating member positioned between the stylus and the arms. An outer flexible sleeve may be circumferentially secured to the arms, lying within or without the plurality of arms. An inner mesh may surround the stylus and dilating member. The device may be introduced into tissue toward a targeted area, while in a closed configuration. The dilating member may be a balloon, wherein upon inflation of the balloon, the arms are pushed radially outward, expanding the device and dilating the surrounding tissue. A cannula may be inserted inside the plurality of arms to keep the arms in an open configuration, and the stylus, balloon and inner mesh may be withdrawn, providing an open passageway through the device to the targeted area. The device may be used with a neural monitoring system. | 06-24-2010 |
| 20120088964 | Methods and devices for pericardial access - Methods and devices for pericardial access are described. One embodiment of a device includes a distal portion with a visualization element, along with a retractable access element. The distal portion is inserted into and navigates through the body to locate the pericardium with the aid of the visualization element. The access element is then extended and used to create an access site in the pericardium, again with the aid of the visualization element. The methods and devices may also be used to access other internal cavities, other soft tissues and organs, and the mediastinal space. | 04-12-2012 |
| 20120088968 | Methods and devices for visualization and access - Methods and devices for visualizing and accessing a region inside a body are described. One embodiment of a device includes a working catheter which slides along an open track in a visualization catheter. The visualization catheter is inserted into the body to locate a region of the body with the aid of the visualization element. The working catheter then slides along the track to reach the region, and a working element is inserted through the working catheter to access the region, again with the aid of the visualization element. The methods and devices may also be used to access a variety of internal cavities, soft tissues and organs, and the mediastinal space. | 04-12-2012 |
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| 20090004105 | Molecular imaging of matrix metalloproteinase expression using labeled chlorotoxin - Embodiments of the present disclosure provide for: methods for imaging MMP-2 positive tissue; methods of diagnosing the presence of one or more of MMP-2 positive precancerous cells, MMP-2 positive cancerous cells, MMP-2 positive tumor cells, and MMP-2 positive diseases in a tissue; method of monitoring the progress of one or more of MMP-2 positive precancerous cells, MMP-2 positive cancerous cells, MMP-2 positive tumor cells, and MMP-2 positive diseases in a tissue; pharmaceutical compositions for imaging one or more of MMP-2 positive precancerous cells, MMP-2 positive cancerous cells, MMP-2 positive tumor cells, and MMP-2 positive diseases; compositions; kits; and the like. | 01-01-2009 |
| 20090136998 | LUCIFERASES AND METHODS FOR MAKING AND USING THE SAME - Briefly described, embodiments of this disclosure include polynucleotides that encode mutant | 05-28-2009 |
| 20100009400 | METHODS OF STUDYING A BIOMARKER, AND METHODS OF DETECTING A BIOMARKER - Embodiments of the present disclosure provide for methods of studying (e.g., detecting, localizing, and/or quantifying) biomarker(s) and the like. | 01-14-2010 |
| 20120178141 | LUCIFERASES AND METHODS FOR MAKING AND USING THE SAME - Briefly described, embodiments of this disclosure include polynucleotides that encode mutant | 07-12-2012 |
| Patent application number | Description | Published |
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| 20090075313 | Split protein fragments, split protein systems, methods of making split protein systems, and methods of using split protein systems - Split protein herpes simplex virus type 1 thymidine kinase [HSV1-TK or TK] TK fragments, split protein TK systems, methods of imaging protein-protein interactions, methods of cellular localization of proteins, methods of evaluating protein translocation and trafficking, and the like, are provided. In addition, the present disclosure includes compositions used in and methods relating to non-invasive imaging (e.g., positron emission tomography (PET) imaging) in vivo and in vitro. | 03-19-2009 |
| 20100008862 | Fluorescent magnetic nanoprobes, methods of making, and methods of use - Embodiments of the present disclosure provide for nanoprobes, methods of imaging, methods of imaging a target, methods of making nanoprobes, and the like. | 01-14-2010 |
| 20110059014 | COMPOUNDS AND METHODS OF MAKING COMPOUNDS - Embodiments of the present disclosure provide for compounds and methods of making compounds such as those shown in FIGS. | 03-10-2011 |
| 20110059439 | COMPOSITION AND METHOD FOR IMAGING STEM CELLS - An expression vector, comprising a first reporter nucleic acid sequence operably linked to a first expression control sequence comprising a promoter; and a second reporter nucleic acid sequence operably linked to a second expression control sequence that comprises a response element that is activated or inactivated as one or more of the cells differentiate or dedifferentiate. Methods and kits for imaging and monitoring stem cells comprising the expression vector are also provided. | 03-10-2011 |
| 20110230760 | Raman imaging devices and methods of molecular imaging - In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to Raman imaging devices (e.g., Raman endoscope probes), methods of using Raman agents and Raman imaging devices to image or detect a signal, and the like. | 09-22-2011 |
