Gales
CĂ©line Gales, Toulouse FR
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20090298162 | BIOSENSORS FOR MONITORING RECEPTOR-MEDIATED G-PROTEIN ACTIVATION - The present invention relates to novel biosensors that are based on bioluminescence resonance energy transfer (BRET). These biosensors may be used to monitor rapid interaction and conformational changes within G protein-coupled receptor/G protein complexes and, in this way, reflect the activation status of the receptor. Advantageously, the biosensors may be used as a highly sensitive and quantitative assay for the identification of ligands (agonists, antagonists, inverse agonists, partial agonists, etc.) targeting G protein-coupled receptors (GPCRs) as well as for the analysis of the activation status of these receptors. Moreover, multiplexing different biosensors within receptors/G protein complexes allows for mapping ligand textures. Additionally, the biosensors permit the direct, real-time examination of interactions between receptors and G protein in their natural environment, the living cell. | 12-03-2009 |
Charles C. Gales, Lancaster, PA US
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20100219042 | PRODUCT INVERTING MECHANISM - The invention is directed to an inverting device which takes one or more articles from a first device, inverts the article(s), and discharges the article(s) onto a second device that may be at essentially the same relative height as the first device. The inverting device has a rotating device with two opposed surfaces that are spaced apart a distance slightly greater than the height of the article. Once the article(s) has been moved into position in the rotating device, the rotating device rotates 180 degrees about a transverse axis, resulting in the inversion of the article. The new orientation of the article may facilitate further processing in a manufacturing environment, such as cleaning, filling, labeling, stacking or any other activity that relies on a specific product disposition. | 09-02-2010 |
Frank Gales, Speyer DE
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20130326087 | MAPPING MESSAGES BETWEEN WEB SERVICES - Techniques for mapping of messages includes receiving, from a first web service, a message comprising one or more operations in a first format; identifying a mapping interface that is based on the first web service, the mapping interface comprising one or more mappings for each of the operations of the message; identifying a second web service that is associated with the identified mapping interface; mapping the message to the second web service such that the one or more operations are in a second format associated with the second web service; and assigning a logical port connection to the second web service. | 12-05-2013 |
20140143221 | Data Access Logging - Data characterizing a plurality of data accesses of objects at one or more log points is received by a data access framework. Thereafter, data accesses requiring logging are identified and one or more corresponding pre-specified attributes are then logged. Related apparatus, systems, techniques and articles are also described. | 05-22-2014 |
Justin Paul Gales, Macedon, NY US
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20150064447 | ADHESIVE WITH EMBEDDED WAVEGUIDES FOR CURING - An optical device includes a support structure configured to retain an optical element using a cured adhesive composition that is disposed between a surface of the support structure and a surface of the optical element, wherein a structured optical particulate material is dispersed throughout the cured adhesive. The structured optical particulate material redirects curing radiation via a scattering mechanism to facilitate curing of portions of the adhesive compositions that cannot be directly exposed to the radiation, thereby facilitating rapid and more thorough curing than could otherwise be achieved without the structured optical particulate material. | 03-05-2015 |
Mark Gales, Wauwatosa, WI US
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20100230199 | MOTORCYCLE HAVING A MULTI-FUNCTIONAL REAR BRAKE CALIPER BRACKET - A motorcycle includes a rear brake caliper bracket coupled to the swingarm. In some constructions, the rear brake caliper bracket includes a caliper mounting portion and a license plate mounting portion. In some constructions, the rear brake caliper bracket includes an axle engaging portion secures and retains the axle relative to the swingarm in a desired position along the axis of rotation. In some constructions, the rear brake caliper bracket is disposed at a laterally outward side of the swingarm and includes a caliper mounting portion, first and second swingarm engaging portions, and an axle engaging portion. In such constructions, the motorcycle may further include an axle adjusting member engaged with the rear brake caliper bracket and operable to adjust the position of the axle relative to the swingarm. | 09-16-2010 |
Mark John Francis Gales, Cambridge GB
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20110015925 | SPEECH RECOGNITION SYSTEM AND METHOD - A speech recognition method, comprising: | 01-20-2011 |
20120041764 | SPEECH PROCESSING SYSTEM AND METHOD - A speech processing method, comprising: | 02-16-2012 |
20120253794 | VOICE CONVERSION METHOD AND SYSTEM - A method of converting speech from the characteristics of a first voice to the characteristics of a second voice, the method comprising: | 10-04-2012 |
20120253811 | SPEECH PROCESSING SYSTEM AND METHOD - A method for identifying a plurality of speakers in audio data and for decoding the speech spoken by said speakers; | 10-04-2012 |
20130262109 | TEXT TO SPEECH METHOD AND SYSTEM - A text-to-speech method for simulating a plurality of different voice characteristics includes dividing inputted text into a sequence of acoustic units; selecting voice characteristics for the inputted text; converting the sequence of acoustic units to a sequence of speech vectors using an acoustic model having a plurality of model parameters provided in clusters each having at least one sub-cluster and describing probability distributions which relate an acoustic unit to a speech vector; and outputting the sequence of speech vectors as audio with the selected voice characteristics. A parameter of a predetermined type of each probability distribution is expressed as a weighted sum of parameters of the same type using voice characteristic dependent weighting. In converting the sequence of acoustic units to a sequence of speech vectors, the voice characteristic dependent weights for the selected voice characteristics are retrieved for each cluster such that there is one weight per sub-cluster. | 10-03-2013 |
20130262119 | TEXT TO SPEECH SYSTEM - A text-to-speech method configured to output speech having a selected speaker voice and a selected speaker attribute, including: inputting text; dividing the inputted text into a sequence of acoustic units; selecting a speaker for the inputted text; selecting a speaker attribute for the inputted text; converting the sequence of acoustic units to a sequence of speech vectors using an acoustic model; and outputting the sequence of speech vectors as audio with the selected speaker voice and a selected speaker attribute. The acoustic model includes a first set of parameters relating to speaker voice and a second set of parameters relating to speaker attributes, which parameters do not overlap. The selecting a speaker voice includes selecting parameters from the first set of parameters and the selecting the speaker attribute includes selecting the parameters from the second set of parameters. | 10-03-2013 |
20140025382 | SPEECH PROCESSING SYSTEM - A text to speech method, the method comprising: | 01-23-2014 |
Nicolas Gales, Pontchateau FR
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20090121540 | HYDRAULIC BRAKE SYSTEM - Embodiments of a hydraulic brake system are disclosed. In one embodiment, a priority flow control valve for supplying operating pressure has a first orientation in which operating pressure is provided at a controlled flow port and a second orientation in which operating pressure is provided at the controlled flow port and an excess flow port. A steering control unit has an inlet port for receiving operating pressure and an outlet port for communicating a steering control load sense signal. A brake control unit has an inlet port for receiving operating pressure and an outlet port for communicating a braking control load sense signal. The inlet port of the brake control unit and the inlet port of the steering control unit are connected to the controlled flow port. | 05-14-2009 |
Nicolas Gales, Pouldreuzic FR
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20130036728 | PUMP SUCTION CHARGING SYSTEM - Disclosed are hydraulic pump systems and pump suction charging systems which reduce or eliminate cavitation in the systems, as well as methods of operating the same and work machines including the same. | 02-14-2013 |
20150081178 | LIFT ARM SUSPENSION SYSTEM FOR A POWER MACHINE - Disclosed are power machines and lift arm suspension or ride control systems for use thereon. A lift arm assembly is pivotally coupled to a frame of the power machine and is capable of being raised and lowered. A selectively activated lift arm suspension system is operably coupled to the lift arm assembly. A controller is coupled to the suspension system and configured to determine whether the lift arm assembly has moved more than a threshold amount. The controller deactivates the lift arm suspension system in response to determining that the lift arm assembly has moved more than the threshold amount. | 03-19-2015 |
20150151762 | VEHICLE START SYSTEM - A power machine with an engine, a drive pump driven by the engine, and a drive motor operably coupled to the drive pump to receive a drive signal and provide a motor output to effect travel of the power machine is disclosed. A brake system on the power machine includes a brake for reducing or stopping movement of the power machine. A controller receives indications of a braking condition and whether the drive pump is outputting the drive signal. The controller determines in response to receipt of the indication of the braking condition whether the drive pump is outputting the drive signal to the drive motor shuts down the engine if the drive pump is providing the drive signal to the drive motor upon receipt of the braking condition. | 06-04-2015 |
Sydney Gales, Verrieres Le Buisson FR
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20150235722 | ARRANGEMENT FOR GENERATING A PROTON BEAM AND AN INSTALLATION FOR TRANSMUTATION OF NUCLEAR WASTES - The invention relates to an arrangement for producing a proton beam. This arrangement is characterized in that it is constituted by a laser driven accelerator of protons adapted to produce a beam of relativistic protons of 0.5 GeV to 1 GeV with a current in the order of tens of mA, such as a current of 20 mA. The invention can be used for transmutating nuclear waste. | 08-20-2015 |