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Gadkar
Kapil Gadkar, Mountain View, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080249751 | Method and Apparatus for Modeling Atherosclerosis - The invention encompasses novel computer models of atherosclerosis and systems for predicting development and progression of atherosclerosis as well as associated cardiovascular risk. In particular, the computer model of atherosclerosis comprises a) a cholesterol metabolism module; b) an atherogenesis module; and c) a plaque stability module. The computer model optionally further comprises a cardiovascular risk module. | 10-09-2008 |
| 20090150134 | Simulating Patient-Specific Outcomes - The invention encompasses systems, methods, and apparatus for predicting clinical outcomes and monitoring an individual's response to a therapeutic regimen. The invention further encompasses methods for predicting cardiovascular risk based a genetic marker status and methods for modifying a computer to reflect genetic data and for incorporating genetic markers into a virtual population. | 06-11-2009 |
| 20100120050 | Biomarkers For Assessing Altherosclerotic Potential - The invention also provides methods, apparatuses and reagents useful for predicting future atherosclerosis based on expression levels of genes selected from the set of 68 genes with differential expression in response to pioglitazone and rosiglitazone. The invention also discloses reagent sets and biomarkers for predicting progression of atherosclerosis induced by anti-diabetic therapy in a subject. In one particular embodiment the invention provides a method for predict whether a compound will induce atherosclerosis using gene expression data from sub-acute treatments. | 05-13-2010 |
M. Gadkar, Maharashtra IN
| Patent application number | Description | Published |
|---|---|---|
| 20080262267 | NOVEL PROCESS - The present invention relates to processes for the preparation of 4-hydroxy-α′-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol 1-hydroxy-2-naphthoate (salmeterol xinafoate) (12a), the preparation of 4-hydroxy-α′-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol (salmeterol) (11), the preparation of protected N-[6-(4-phenylbutoxy)hexyl]amine intermediates (7), and the preparation of 6-substituted (4-phenylbutoxy)hexane intermediates (5), shown below, wherein X is a leaving group and Pg is a protecting group. | 10-23-2008 |
Mahesh Gadkar, Herfordshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20100292290 | NOVEL PROCESS TO PREPARE ALMOTRIPTAN - The present invention relates to a novel process for the preparation of almotriptan and pharmaceutically acceptable salts thereof, which affords product conveniently and efficiently with commercially acceptable yields and purity. The present invention also relates to a novel synthetic intermediate used in the process. | 11-18-2010 |