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Gaddipati

Ajeetkumar Gaddipati, Waukesha, WI US

Patent application numberDescriptionPublished
20110025325APPARATUS AND METHOD FOR ACQUISITION AND RECONSTRUCTION OF NON-CPMG PROPELLER SEQUENCES - An apparatus and method of MR imaging is disclosed. The apparatus and method comprises segmenting acquisition of an echo train into separate odd and even acquisition blades in k-space, wherein the odd and even acquisition blades extend orthogonally through a common reference point in a central region of k-space. A segment of MR data is acquired using a quadratic phase modulation scheme, wherein a first set of MR echo signals occurring after odd-numbered RF refocusing pulses are stored in the odd acquisition blade, and a second set of MR echo signals occurring after even-numbered RF refocusing pulses are stored in the even acquisition blade. This acquisition and segmentation is repeated until a sufficient number of blades are acquired to fill k-space. Finally, an image is reconstructed from the acquisition blades.02-03-2011

Deepak Kumar Gaddipati, Kokomo, IN US

Patent application numberDescriptionPublished
20090196475AUTOMATIC MASK DESIGN AND REGISTRATION AND FEATURE DETECTION FOR COMPUTER-AIDED SKIN ANALYSIS - Methods and systems for automatically generating a mask delineating a region of interest (ROI) within an image containing skin are disclosed. The image may be of an anatomical area containing skin, such as the face, neck, chest, shoulders, arms or hands, among others, or may be of portions of such areas, such as the cheek, forehead, or nose, among others. The mask that is generated is based on the locations of anatomical features or landmarks in the image, such as the eyes, nose, eyebrows and lips, which can vary from subject to subject and image to image. As such, masks can be adapted to individual subjects and to different images of the same subjects, while delineating anatomically standardized ROIs, thereby facilitating standardized, reproducible skin analysis over multiple subjects and/or over multiple images of each subject. Moreover, the masks can be limited to skin regions that include uniformly illuminated portions of skin while excluding skin regions in shadow or hot-spot areas that would otherwise provide erroneous feature analysis results. Methods and systems are also disclosed for automatically registering a skin mask delineating a skin ROI in a first image captured in one imaging modality (e.g., standard white light, UV light, polarized light, multi-spectral absorption or fluorescence imaging, etc.) onto a second image of the ROI captured in the same or another imaging modality. Such registration can be done using linear as well as non-linear spatial transformation techniques.08-06-2009

Jaya Gaddipati, Boyds, MD US

Patent application numberDescriptionPublished
20090155232Neonatal human hepatocytes immortalized using tert and methods of their use - The present invention relates to the discovery of immortalized neonatal human hepatocytes that exhibit phenotypic features of human hepatic progenitor cells. The invention is also directed to a method of obtaining telomerase-immortalized neonatal human hepatocytes that exhibit phenotypic features of human hepatic progenitor cells. Furthermore, the instant invention describes methods of using the immortalized neonatal human hepatocytes in cellular therapies, toxicological studies, pharmacokinetic studies, metabolic studies, therapeutic gene delivery and for the production of fully differentiated hepatocytes.06-18-2009