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Gabriela Alexandru, Pasadena, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090192084 | Compositions and method of treating hypoxia-associated diseases - Hypoxia, a state of lower than normal tissue oxygen tension, has recently been implicated in a host of human diseases, including cancer, heart disease, and neurological disorders. Novel associations between p97 and other proteins, including UBX-domain-containing proteins (UBX-polypeptides), HIF1α, and a variety of E3 ligases are provided herein. The disclosure provides complexes comprising UBX-domain-containing polypeptides (UBX-polypeptides) and other polypeptides involved in the degradation of ubiquitinated proteins. In addition, the disclosure provides uses for active agents that modulate protein-protein complex formation between an UBX-polypeptide and its complementary-binding substrate. For example, the disclosure provides methods for treating or preventing hypoxia-related disorders or conditions in a patient or a cell by administration of an active agent that modulates the activity of an UBX-polypeptide and/or its complementary binding-substrate. Furthermore, the disclosure provides uses for active agents that modulate HIF1α activity; such agents may be used to modulate processes that are regulated by HIF1α. The disclosure also provides many screening assays to identify test agents that modulate complex formation between an UBX-polypeptide and its complementary-binding substrate or methods for evaluating modes of action and/or effects of active agents that have already been identified as modulators of an UBX-polypeptide and/or its complementary-binding substrate. | 07-30-2009 |
Gabriela Alexe, Medford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080313135 | METHOD OF IDENTIFYING ROBUST CLUSTERING - A method of finding robust clusters comprises the use of principal component analysis and consensus ensemble clustering. In another aspect, the method may comprise normalizing a data set; identifying attributes of the data set that contribute to most of variation in the normalized data set; selecting data having the attributes that contribute to most of variation in the normalized data set; identifying a plurality of clusters from the selected data using consensus ensemble clustering; and identifying robust clusters from the plurality of clusters. The method can be used in healthcare and life science. | 12-18-2008 |
Gabriela Alvarez Jürgenson, Mannheim DE
| Patent application number | Description | Published |
|---|---|---|
| 20110083846 | PROCESS FOR TERTIARY MINERAL OIL PRODUCTION USING SURFACTANT MIXTURES - A process for mineral oil production, especially Winsor type III microemulsion flooding, in which an aqueous surfactant formulation which comprises at least one nonionic surfactant having 8 to 30 ethoxy units, which has a polydispersity of from 1.01 to 1.12, and at least one further surfactant is forced through injection wells into a mineral oil deposit and crude oil is removed from the deposit through production wells. | 04-14-2011 |
| 20110083847 | PROCESS FOR TERTIARY MINERAL OIL PRODUCTION USING SURFACTANT MIXTURES - A process for mineral oil production, especially Winsor type III microemulsion flooding, in which an aqueous surfactant formulation which comprises at least one alkylpolyalkoxysulfate comprising propoxy groups, and at least one further surfactant differing therefrom is used, is forced through injection wells into a mineral oil deposit and crude oil is removed from the deposit through production wells. The alkylpolyalkoxysulfate comprising propoxy groups is prepared in this case by sulfating an alkoxylated alcohol, the alkoxylated alcohol being prepared by alkoxylating an alcohol using double metal cyanide catalysts or double hydroxide clays. | 04-14-2011 |
| 20110083848 | PROCESS FOR MINERAL OIL PRODUCTION USING SURFACTANT MIXTURES - A process for mineral oil production especially Winsor type III microemulsion flooding, in which an aqueous surfactant formulation which comprises at least one nonionic surfactant having 11 to 40 ethoxy units and a hydrophobic radical having 8 to 32 carbon atoms and at least one further surfactant differing therefrom is forced through injection wells into a mineral oil deposit and crude oil is removed from the deposit through production wells. | 04-14-2011 |
| 20110220353 | USE OF SURFACTANT MIXTURES OF POLYCARBOXYLATES FOR MICROEMULSION FLOODING - The present invention relates to processes for tertiary mineral oil production with the aid of a surfactant mixture and to the use of a surfactant mixture for tertiary mineral oil production by means of Winsor type III microemulsion flooding, by injecting a surfactant mixture through at least one aqueous injection borehole into a mineral oil deposit, and withdrawing crude oil from the deposit through at least one production borehole, wherein the surfactant mixture, for the purpose of lowering the interfacial tension between oil and water to <0.1 mN/m, comprises at least the following components: (a) one or more polycarboxylate(s) comprising at least 50 mol % of acrylic acid units and/or methacrylic acid units and/or maleic acid units and/or itaconic acid units or salts thereof, and (b) one or more anionic and/or nonionic surfactant(s). | 09-15-2011 |
| 20110220364 | PROCESS FOR MINERAL OIL PRODUCTION USING CATIONIC SURFACTANTS HAVING A HYDROPHOBIC BLOCK WITH A CHAIN LENGTH OF 6 TO 10 CARBON ATOMS - The invention relates to a process for mineral oil production by means of Winsor type III microemulsion flooding, in which an aqueous surfactant formulation comprising at least one ionic surfactant of the general formula R | 09-15-2011 |
| 20110220365 | PROCESS FOR PRODUCING MINERAL OIL USING SURFACTANTS BASED ON C16C18-CONTAINING ALKYL PROPOXY SURFACTANTS - The invention relates to a process for mineral oil production by means of Winsor Type III microemulsion flooding, in which an aqueous surfactant formulation comprising at least one ionic surfactant of the general formula R | 09-15-2011 |
| 20110220366 | PROCESS FOR EXTRACTING MINERAL OIL USING SURFACTANTS BASED ON BUTYLENE OXIDE-CONTAINING ALKYL ALKOXYLATES - The invention relates to a process for mineral oil extraction by means of Winsor Type III microemulsion flooding, in which an aqueous surfactant formulation comprising at least one ionic surfactant of the general formula R | 09-15-2011 |
| 20110259583 | PROCESS FOR EXTRACTING MINERAL OIL USING SURFACTANTS, ESPECIALLY BASED ON C35 SECONDARY ALCOHOL-CONTAINING ALKYL ALKOXYLATES - The present invention relates to a process for mineral oil extraction by means of Winsor Type III microemulsion flooding, in which an aqueous surfactant formulation comprising at least one ionic surfactant of the general formula (R | 10-27-2011 |
| 20110263467 | PROCESS FOR PRODUCING MINERAL OIL USING SURFACTANTS BASED ON A MIXTURE OF C32 GUERBET-, C34 GUERBET-, C36 GUERBET-CONTAINING ALKYL ALKOXYLATES - The present invention relates to a process for mineral oil extraction by means of Winsor type III microemulsion flooding, in which an aqueous surfactant formulation comprising at least three ionic surfactants which are different with regard to the alkyl moiety (R | 10-27-2011 |
Gabriela Alvarez Jürgenson, Mannheim DE
| Patent application number | Description | Published |
|---|---|---|
| 20110083846 | PROCESS FOR TERTIARY MINERAL OIL PRODUCTION USING SURFACTANT MIXTURES - A process for mineral oil production, especially Winsor type III microemulsion flooding, in which an aqueous surfactant formulation which comprises at least one nonionic surfactant having 8 to 30 ethoxy units, which has a polydispersity of from 1.01 to 1.12, and at least one further surfactant is forced through injection wells into a mineral oil deposit and crude oil is removed from the deposit through production wells. | 04-14-2011 |
| 20110083847 | PROCESS FOR TERTIARY MINERAL OIL PRODUCTION USING SURFACTANT MIXTURES - A process for mineral oil production, especially Winsor type III microemulsion flooding, in which an aqueous surfactant formulation which comprises at least one alkylpolyalkoxysulfate comprising propoxy groups, and at least one further surfactant differing therefrom is used, is forced through injection wells into a mineral oil deposit and crude oil is removed from the deposit through production wells. The alkylpolyalkoxysulfate comprising propoxy groups is prepared in this case by sulfating an alkoxylated alcohol, the alkoxylated alcohol being prepared by alkoxylating an alcohol using double metal cyanide catalysts or double hydroxide clays. | 04-14-2011 |
| 20110083848 | PROCESS FOR MINERAL OIL PRODUCTION USING SURFACTANT MIXTURES - A process for mineral oil production especially Winsor type III microemulsion flooding, in which an aqueous surfactant formulation which comprises at least one nonionic surfactant having 11 to 40 ethoxy units and a hydrophobic radical having 8 to 32 carbon atoms and at least one further surfactant differing therefrom is forced through injection wells into a mineral oil deposit and crude oil is removed from the deposit through production wells. | 04-14-2011 |
| 20110281779 | Novel Anionic Polyalkoxy Group Comprising Surfactants on Basis of Guerbet-Alcohols, Method of Manufacture and Use in Enhanced Oil Recovery (EOR) Applications - Compositions and methods of synthesis of anionic surfactants by alkoxylation of a Guerbet alcohol (GA) having 12 to 36 carbon atoms using butylene oxide, and optionally propylene oxide and/or ethylene oxide followed by the incorporation of a terminal anionic group are described herein. The GA of the present invention is made by a facile and inexpensive method that involves high temperature base catalyzed dimerization of alcohols with 6 to 18 carbon atoms. The large hydrophobe ether surfactants of the present invention find uses in enhanced oil recovery (EOR) applications where it is used for solubilization and mobilization of oil and for environmental cleanup. Further, the hydrophobe alkoxylated GA without anionic terminal group can be used as an ultra-high molecular weight non-ionic surfactant. | 11-17-2011 |
Gabriela Ambrozic, Ljubljana SI
| Patent application number | Description | Published |
|---|---|---|
| 20110092420 | SELENIUM CONTAINING MODIFYING AGENTS AND CONJUGATES - The invention relates to a modifying agent comprising a water soluble polymer, wherein the water soluble polymer comprises at least one reactive selenium group, said reactive selenium group being capable of reacting with a thiol group thereby forming an —Se—S— bond. Furthermore, the invention relates to a method for producing said modifying agents and their use in the modification of pharmaceutically active agents, e.g. G-CSF. Additionally, the invention concerns conjugates comprising a water-soluble polymer and a pharmaceutically active agent, wherein the water-soluble polymer is linked via a S—Se-bond to agent and a method for their production and their use as medicaments. Finally, the invention concerns a pharmaceutical composition comprising the inventive conjugates. | 04-21-2011 |
Gabriela Apiou, Paris FR
| Patent application number | Description | Published |
|---|---|---|
| 20080295830 | Tool and method for customized inhalation - A method for designing and/or customizing the treatment or for treating by inhalation of a patient suffering from a respiratory or non-respiratory disease including the steps of presenting a patient suffering from the disease; determining the kind of disease of the patient; prescribing at least one drug and/or gas and at least one kind of device to be used for administrating the drug or gas; inputting into a processing element, data chosen among the drug and/or prescribed gas and drug particle size obtained with the prescribed device; inputting into the processing element at least one patient characteristics of the patient; inputting into processing element at least one morphology and/or ventilatory condition of the patient; running a code in the processing element using the input data and conditions thereby calculating a flow and/or deposition characteristics customized to the patient. | 12-04-2008 |
| 20100074966 | Gaseous Mixture Containing O2 and N2O For Preventing Or Reducing Hyperalgesia - The invention relates to a gaseous mixture containing oxygen and nitrous oxide in a nitrous oxide proportion of between 5 and 15 vol. %, that can be used for producing a drug for preventing or reducing hyperalgesia in human beings or animals, in particular a post-operation opioid-induced hyperalgesia. | 03-25-2010 |
Gabriela Bergonzelli, Bussigny-Pres Lausanne CH
| Patent application number | Description | Published |
|---|---|---|
| 20080254012 | Nutritional Formulation For Promoting Catch-Up Growth - This invention relates to a nutritional formulation comprising an n3 long-chain polyunsaturated fatty acid (LC-PUFA), a prebiotic fibre and a probiotic bacterial strain which ingredients act together in a synergistic fashion to promote catch-up growth in young mammals whose growth has been retarded because the young mammal has been subjected to physical or mental stress. | 10-16-2008 |
| 20100028316 | MODERATING THE EFFECT OF ENDOTOXINS - The present invention relates to the use of an oral composition comprising yeast extract, in the manufacture of an oral composition to treat the effects of infection by pathogenic bacteria such as | 02-04-2010 |
Gabriela Bergonzelli, Bussigny CH
| Patent application number | Description | Published |
|---|---|---|
| 20110280837 | BIFIDOBACTERIUM LONGUM AND HIPPOCAMPAL BDNF EXPRESSION - The present invention relates in general to edible compositions comprising probiotics. One embodiment of the present invention relates to an edible composition comprising | 11-17-2011 |
Gabriela Bergonzelli Degonda, Bussigny CH
| Patent application number | Description | Published |
|---|---|---|
| 20110206649 | NUTRITIONAL COMPOSITION COMPRISING PROBIOTICS AND IMPROVING SLEEP PATTERNS - This invention relates to the use of a probiotic bacterial strain in the manufacture of a medicament or therapeutic nutritional composition for improving the maturation of sleep patterns in infants, young children or young animals and/or for reducing sleep disturbances and/or improving sleep patterns in humans or animals at any age. | 08-25-2011 |
| 20110223282 | NUTRITIONAL COMPOSITION WITH ANTI-REGURGITATION PROPERTIES - A nutritional composition for the management of regurgitation in infants which composition includes which composition includes a protein source consisting essentially of partially hydrolysed proteins, a lipid source and a carbohydrate source comprising a starch selected from cereal starch or potato starch wherein the starch amounts to between 18 to 25% of the nutritional composition on a dry weight basis. | 09-15-2011 |
Gabriela Binasch, Eindhoven NL
| Patent application number | Description | Published |
|---|---|---|
| 20080258995 | Display Device - The present invention relates to a dual view display device where a display surface is divided into a first and a second sub-section ( | 10-23-2008 |
Gabriela Bunea, Santa Clara, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110048505 | Module Level Solution to Solar Cell Polarization Using an Encapsulant with Opened UV Transmission Curve - A solar cell module includes interconnected solar cells, a transparent cover over the front sides of the solar cells, and a backsheet on the backside of the solar cells. An encapsulant protectively packages the solar cells. The encapsulant and the transparent cover forms a top protection package that has a combined UV transmission curve and volume specific resistance that addresses polarization. The encapsulant has a relatively wide UV transmission curve. | 03-03-2011 |
Gabriela Caldero-Linnhoff, Barcelona ES
| Patent application number | Description | Published |
|---|---|---|
| 20090028916 | Loaded Microspheres - The invention relates to loaded microspheres with a mean diameter of 0.001 to 1 mm, and loaded with one or more absorbed or adsorbed active principles, which are obtained by mixing fine-particle polymethyl methacrylate or methyl methacrylate cross polymer with lipophilic or hydrophilic active principles until they have been absorbed or adsorbed by the surface of the polymer and a dry powder, granules or a paste is obtained. When applied to textile or fiber finishing, the loaded microspheres provide extended release of active cosmetic or pharmaceutical active principles. | 01-29-2009 |
Gabriela Canziani, Blue Bell, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110027294 | Anti-Respiratory Syncytial Virus Antibodies, Antigens and Uses Thereof - Anti-Respiratory Syncytial Virus (RSV) monoclonal antibodies, RSV F protein antigens and their uses are disclosed. | 02-03-2011 |
Gabriela Ce, Porto Alegre BR
| Patent application number | Description | Published |
|---|---|---|
| 20080241796 | Apparatus for Digitalization of Dental Structures, and Method for Recognition of Three-Dimensional Data of Dental Structures - An apparatus for digitalization of dental structures which is precise and efficient, generating unequivocal three-dimensional data. The apparatus of the invention comprises at least one articulated arm and at least one probe, said articulated arm and probe providing dental structure scanning directly by mouth contact, being a comfortable device for the patient. The method of the invention provides an advantageous way by which dental structure moulds can be produced, since it generates very accurate three-dimensional data of the dental. | 10-02-2008 |
Gabriela Cezar, Middleton, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20110081675 | Metabolic Biomarkers Of Drug-Induced Cardiotoxicity - The invention provides methods and biomarkers for assessing cardiac metabolic response to pharmaceuticals, environmental agents, chemical compounds and biologic therapies. The invention provides methods for identifying cellular metabolites secreted by primary cardiomyocytes, cardiomyocyte precursor cells, clonal cardiomyocytes derived from adult human heart, immortalized cardiomyocytes, human embryonic stem cell (hESC)-derived cardiomyocytes, human induced pluripotent stem cell (iPS)-derived cardiomyocytes, or any cell displaying cardiomyocyte-specific markers in response to exposure to pharmaceuticals, environmental agents, chemical compounds and biologic therapies that are cardiotoxic. Cardiomyocyte-secreted cellular metabolites provide metabolic signatures of cardiotoxicity, and can be used to screen pharmaceutical agents, lead and candidate drug compounds, biologics, and other therapeutics for cardiotoxic effects. | 04-07-2011 |
Gabriela Chiosis, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080253965 | Small-Molecule Hsp90 Inhibitors - Hsp90 inhibitors are provided having the formula: | 10-16-2008 |
| 20090298857 | Treatment of Neurodegenerative Diseases Through Inhibition of HSP90 - Treatment of neurodegenerative diseases is achieved using small molecule purine scaffold compounds that inhibit Hsp90 and that possess the ability to cross the blood-brain barrier or are other wise delivered to the brain. | 12-03-2009 |
| 20110104054 | Small-Molecule HSP90 Inhibitors - Hsp90 inhibitors having are provided having the formula: | 05-05-2011 |
Gabriela Cochius, Diessen DE
| Patent application number | Description | Published |
|---|---|---|
| 20110164028 | METHOD AND DEVICES FOR CALIBRATING A DISPLAY UNIT COMPRISING A DISPLAY AND AUTOSTEREOSCOPIC ADAPTER DISC - A method and a device for calibration (or “electronic” adjustment) of a display unit are provided and include a display and autostereoscopic adapter disc, particularly provided for fixing to the display. A method and advice for generation or playback of 3D images by the display unit including autostereoscopic adapter disc and display are also provided. Misalignment of the adapted disc with the display are compensated for by corresponding adjustment of the image display on the display. | 07-07-2011 |
Gabriela Cocora, Elsenfeld-Eichelsbach DE
| Patent application number | Description | Published |
|---|---|---|
| 20090188525 | Apparatus, carrier and method for the plasma treatment of molds - An apparatus for the plasma treatment of molds ( | 07-30-2009 |
| 20100309251 | MAINTENANCE UNIT FOR PRINT HEAD - The present invention generally relates to a printing apparatus including one or more print heads for depositing printing fluid onto a substrate, wherein the apparatus comprises a maintenance unit for the one or more print heads. The present invention further relates to a method for cleaning one or more print heads from adhering printing fluid. The present invention also relates to the use of said apparatus in the automated manufacture of a contact lens, in particular a silicone hydrogel contact lens. | 12-09-2010 |
| 20110089586 | Process For Manufacturing An Ophthalmic Lens - There is described a process for manufacturing an ophthalmic lens and an apparatus for forming an ophthalmic lens, in particular a silicone hydrogel contact lens, wherein in a mold assembly a first and a second mold half ( | 04-21-2011 |
| 20110101552 | METHOD FOR MAKING A COLORED CONTACT LENS - The present invention relates to a method for the manufacture of a contact lens with a printed image thereon, in particular a silicone hydrogel contact lens with a printed image thereon, comprising applying one or more ink drops to at least a portion of at least one molding surface of a lens mold, wherein each ink drop is sufficiently flat, that the forces exerted by the mold surface to the ink drop surface in the area where they make contact, are higher than the forces exerted by the flowing lens forming material to the facing surface of the ink drop, and wherein the ink material and the lens forming material are sufficiently immiscible or not miscible at all. | 05-05-2011 |
Gabriela Csurka, Crolles FR
| Patent application number | Description | Published |
|---|---|---|
| 20080284791 | FORMING COLORING BOOKS FROM DIGITAL IMAGES - Embodiments herein include a method, service, apparatus, etc., that automatically generates a coloring book image that includes line drawings defining a small number of color coherent, clearly discriminated, closed regions while preserving the basic semantic properties of the original image. These regions hence can be filled in with colored inks, crayons, paints, etc. The method inputs a color image that can be a photograph, scanned image, etc. The method begins by transforming the color image into a chrominance-luminance space and then performs low pass filtering on the color image that preserves the chrominance edges of the features within the color image. Next, the method segments the color image into the features based on locations of the chrominance edges of the features. Then, the method can merge selected features into other features. After performing any merging, the method identifies the remaining chrominance edges of the features within the image and adds lines along the remaining chrominance edges to form outlines of the features. Then, the method automatically filters out all other data from the image to leave only the outlines and produce a revised image consisting of just the outlines. The revised image of just outlines is then output to the user. | 11-20-2008 |
| 20080317358 | CLASS-BASED IMAGE ENHANCEMENT SYSTEM - A method for image enhancement includes providing for a semantic class to be assigned to a digital image based on image content, the assigned semantic class being selected from a plurality of semantic classes. The method further includes providing for an aesthetic enhancement to be applied to the image based on image quality of the image and the assigned semantic class, the enhancement including at least one enhancement dimension selected from a plurality of enhancement dimensions. | 12-25-2008 |
| 20090208118 | CONTEXT DEPENDENT INTELLIGENT THUMBNAIL IMAGES - An apparatus and method are disclosed for context dependent cropping of a source image. The method includes identifying a context for the source image, identifying a visual class corresponding to the identified context from a set of visual classes, applying a class model to the source image to identify a candidate region of the image based on its relevance to the visual class, and identifying a subpart of the source image for cropping, based on the location of the candidate region. | 08-20-2009 |
| 20100040285 | SYSTEM AND METHOD FOR OBJECT CLASS LOCALIZATION AND SEMANTIC CLASS BASED IMAGE SEGMENTATION - An automated image processing system and method are provided for class-based segmentation of a digital image. The method includes extracting a plurality of patches of an input image. For each patch, at least one feature is extracted. The feature may be a high level feature which is derived from the application of a generative model to a representation of low level feature(s) of the patch. For each patch, and for at least one object class from a set of object classes, a relevance score for the patch, based on the at least one feature, is computed. For at least some or all of the pixels of the image, a relevance score for the at least one object class based on the patch scores is computed. An object class is assigned to each of the pixels based on the computed relevance score for the at least one object class, allowing the image to be segmented and the segments labeled, based on object class. | 02-18-2010 |
| 20100210358 | MODIFICATION OF IMAGES FROM A USER'S ALBUM FOR SPOT-THE-DIFFERENCES - A computer implemented system and method for generating a game, such as spot-the-difference are provided. The method includes receiving a user-selected original image and storing the image in memory. From the original image, the method includes automatically generating a pair of images which are visually identical except for a predetermined number of random localized modifications, and providing the pair of images to the user as a game which can be played by spotting differences between the pair of images as a result of the modifications. | 08-19-2010 |
| 20100226564 | FRAMEWORK FOR IMAGE THUMBNAILING BASED ON VISUAL SIMILARITY - An apparatus and method for detecting a region of interest in an image are disclosed. Image representations for a set of images that have been manually annotated with regions of interest are stored, along with positive and negative representations of each image which are similarly derived to the image representations except that they are based on features extracted from patches within the region of interest and outside it, respectively. For an original image for which a region of interest is desired, the stored information for K similar images is automatically retrieved and used to train a classifier. The trained classifier provides, for each patch of the original image, a probability of being in a region of interest, based extracted features of the patch (represented, for example, as a Fisher vector), which can be used to determine a region of interest in the original image. | 09-09-2010 |
| 20110052063 | CONSISTENT HIERARCHICAL LABELING OF IMAGE AND IMAGE REGIONS - Classification of image regions comprises: recursively partitioning an image into a tree of image regions having the image as a tree root and at least one image patch in each leaf image region of the tree, the tree having nodes defined by the image regions and edges defined by pairs of nodes connected by edges of the tree; assigning unary classification potentials to nodes of the tree; assigning pairwise classification potentials to edges of the tree; and labeling the image regions of the tree of image regions based on optimizing an objective function comprising an aggregation of the unary classification potentials and the pairwise classification potentials. | 03-03-2011 |
| 20110184950 | SYSTEM FOR CREATIVE IMAGE NAVIGATION AND EXPLORATION - A system and method for assisting a user in navigation of an image dataset are disclosed. The method includes receiving a user's text query, retrieving images responsive to the query from an image dataset, providing for receiving the user's selection of a first feature selected from a set of available first features via a graphical user interface, providing for receiving the user's selection of a second feature selected from a set of available second features different from the first features via the graphical user interface, and displaying at least some of the retrieved images on the graphical user interface. The displayed images are arranged, e.g., grouped, according to levels and/or combinations of levels of the user-selected first and second features. | 07-28-2011 |
Gabriela Diego-Gomez, Milton, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080293470 | ELECTRONIC OUTDOOR GAME APPARATUS - In one aspect, an outdoor game system is provided, comprising a plurality of upright towers that are operatively connected and suitable for installation outdoors, each tower including a plurality of contact assemblies, each contact assembly including an interface capable of responding to or detecting contact, a light source that emits light proximate the interface, and a sound source that emits sounds proximate the interface, wherein the contact assemblies operate in random or predetermined sequences that constitute game functions. In another aspect, an outdoor game system is provided, comprising four towers, each tower including four interfaces, each interface detecting or responding to contact, at least one light source, and at least one sound source, wherein the interfaces define a four-by-four grid, and the four-by-four grid is entirely visible from a single location within a field of play. | 11-27-2008 |
Gabriela Dontu, Ann Arbor, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100291581 | Aldehyde Dehydrogenase 1 (ALDH1) as a Cancer Stem Cell Marker - The present invention relates to compositions and methods for treating, characterizing, and diagnosing cancer. In particular, the present invention provides a novel stem cell cancer marker, ALDH | 11-18-2010 |
Gabriela Ferreres, Kirkland, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100088376 | Obtaining content and adding same to document - Mechanisms to assist a user in obtaining content may be integrated with the tools that allow the user to author an e-mail message or any other type of document. For example, an e-mail composition system may offer various buttons that allow users to obtain certain types of content—e.g., movie times, restaurant menus, etc. When the user clicks the button, the requested type of content may be obtained, and the user may be offered the opportunity to insert the obtained content into the document that is being authored. The content that is obtained may follow a particular structure. For example, a system might be configured to respond to a request for movie-related content by returning a list of show-times and theaters for a particular movie. | 04-08-2010 |
Gabriela Isturiz, Pittsburgh, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090106132 | Electronic billing system utilizing a universal billing format data transmission - The electronic billing system comprises a means for isolating the service provider from directly engaging the billing guidelines of the consumer client through the use of a universal billing format file and a billing hub module. The billing process comprises a service provider computer system, on which specific billing data is stored, a service provider application that accesses the billing data and compiles a universal billing format file, a validation process to ensure that the billing data satisfies billing guidelines supplied by the service consumer, and a billing hub module that receives the universal billing format file and reconfigures the individual billing data entries into a client invoice that complies with the billing guidelines supplied by the service consumer. | 04-23-2009 |
Gabriela Jacques De Silva, Champaign, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20080307258 | Distributed Job Manager Recovery - A method is provided for the recovery of an instance of a job manager running on one of a plurality of nodes used to execute the processing elements associated with jobs that are executed within a cooperative data stream processing system. The states of the processing elements are checkpointed to a persistence mechanism in communication with the job manager. From the checkpointed processing element states, the state of each distributed job is determined and checkpointed. Processing element states are also checkpointed locally to the nodes one which the processing elements are running. Following a failure of the job manager, the job manager is reinstantiated on one of the nodes. The recovery instance of the job manger obtains state data for processing elements and jobs from the persistence mechanism and constructs an initial state for jobs and processing elements. These initial states are reconciled against the current states of the processing elements and adjustments are made accordingly. Once the job and processing element states are reconciled, the system is returned to normal operation. | 12-11-2008 |
Gabriela Kornek, Vienna AT
| Patent application number | Description | Published |
|---|---|---|
| 20100034816 | Treatment of Diabetes by at Least One Epidermal Growth Factor Receptor Specific Antibody or a Derivative Thereof - The present invention relates to the use of at least one epidermal growth factor receptor specific antibody or a derivative thereof for the manufacture of a medicament for the treatment of diabetes, in particular of the advanced insulin-dependent stage of diabetes mellitus Type 1 and 2 in humans as well as in animals. | 02-11-2010 |
Gabriela Kramer-Marek, Washington, DC US
| Patent application number | Description | Published |
|---|---|---|
| 20100254899 | RADIOLABELED AFFIBODY MOLECULES - The invention provides a radiolabeled affibody molecule comprising a fragment of an IgG-binding domain of protein A from | 10-07-2010 |
Gabriela Mihalascu, Burgheim DE
| Patent application number | Description | Published |
|---|---|---|
| 20110272524 | INTEGRATED MAINTENANCE STEP ON HELICOPTER FUSELAGE - Maintenance steps on helicopters ( | 11-10-2011 |
Gabriela Mladenova, Thornhill CA
| Patent application number | Description | Published |
|---|---|---|
| 20090131503 | 3,5 - SUBSTITUTED INDOLE COMPOUNDS HAVING NOS AND NOREPINEPHRINE REUPTAKE INHIBITORY ACTIVITY - The present invention relates to novel 3,5-substituted indole compounds of Formula (I) having nitric oxide synthase (NOS) inhibitory activity together with inhibitory activity at the norepinephrine transporter (NET), to pharmaceutical and diagnostic compositions containing them, and to their medical use. | 05-21-2009 |
| 20090192157 | INDOLE COMPOUNDS AND METHODS FOR TREATING VISCERAL PAIN - The invention features methods of treating visceral pain or a condition in a mammal caused by the action of nitric oxide synthase (NOS) or by the action of serotonin 5HT1D/1B receptors, by administering to a patient in need thereof a therapeutically effective amount of an indole compound of Formula (I), or a pharmaceutically acceptable salt or prodrug thereof. The methods of the invention may further comprise the administration of additional therapeutic agent. The invention also features new compounds of Formula (I), pharmaceutical compositions thereof, and methods of resolving enantiomeric mixtures. | 07-30-2009 |
Gabriela Mustata, Cranberry Township, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090220451 | CYCLOPROPYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS - Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. | 09-03-2009 |
Gabriela Negroiu, Bucharest RO
| Patent application number | Description | Published |
|---|---|---|
| 20080280972 | Iminosugar treatment of tumors - A proliferation of cells can be reduced by contacting the cells with a compound having formula (I) | 11-13-2008 |
Gabriela Ramos Leal, Guadalajara Jalisco MX
| Patent application number | Description | Published |
|---|---|---|
| 20100268300 | LOW FREQUENCY ELECTRICAL STIMULATOR DEVICE FOR THE PREVENTION AND TREATMENT OF CHRONIC WOUNDS - A low frequency electrical stimulation device for the prevention and healing of chronic wounds resulting from diabetes, or other type of pathology. This device applies electrical stimulation through a square bipolar signal, and a paused squared bipolar signal in at least one of the output channels, and at different therapy times and frequencies that will depend upon the specific needs of the patient. | 10-21-2010 |
Gabriela Roche Del Ayala, Monterrey MX
| Patent application number | Description | Published |
|---|---|---|
| 20090312729 | Sanitary Napkin with Braid - The present invention relates to a sanitary napkin whose securing means includes a “braid” of absorbent material. The braid structure maximizes absorbency, while minimizing bulk and thus allows the pad to be comfortably held in place during use, in much the same way that the popular underwear are held. | 12-17-2009 |
Gabriela Saborio, Dingy En Vuache FR
| Patent application number | Description | Published |
|---|---|---|
| 20100260785 | SARP-1 Fusion Proteins and Uses Thereof - The invention relates to a fusion protein comprising a mature SARP-1 polypeptide without the Netrindomain, the fusion protein further comprising an Fc region of an immunoglobulin, wherein the fusion protein lacks certain N-terminal amino acids of the mature SARP-1 polypeptide. The invention further relates to the use of said fusion protein for treating cancer, a fibrotic disorder or a cardiovascular disorder. | 10-14-2010 |
Gabriela Salinas-Riester, Gottingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20100008935 | METHOD FOR IDENTIFYING THERAPEUTICAL TARGETS IN TUMORS, THE USE THEREOF AND MEANS FOR DETERMINING AND TARGETING ANGIOGENESIS AND HEMOSTASIS RELATED TO ANDENOCARCINOMAS OF THE LUNG - Vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF/SF) are potent mitogens with proven angiogenic activities in human and animal disease models. These growth factors display little overlap in angiogenesis signaling cascades. The application reports angiogenesis in lung adenocarcinomas to be coordinated by hemostatic events. The invention relates to a method for identifying therapeutical targets in tumors, in particular in advanced stage tumor malignancies, the use of novel targets for identifying, determining, and targeting angiogenesis and hemostasis related to adenocarcinomas of the lung, and the use of the therapeutical targets identified for screening and determining means and/or drugs. The aim of the present invention is therefore to make available an easy and efficient method for identifying therapeutical targets in tumors, in particular in advanced stage tumor malignancies. Furthermore the aim is the use of novel therapeutical targets identified by the method for screening and determining beneficial means and/or drugs, and means and drugs for identifying, determining and treating angiogenesis and hemostasis related to adenocarcinomas, in particular of advanced stage tumors of the lung. The method for identifying therapeutical targets in tumors, in particular in advanced stage tumor malignancies, comprising the steps of—isolating RNA (1) from the tissue of the tumor; —determining for the isolated RNA (1) a gene expression profile (2) of at least two genes, wherein at least one gene (3) is coding for a VEGF activity modulator and at least one gene (4) is coding for a hemostatic factor by screening the presence of mRNA coding for the factors to be screened and by determining the levels of expression of thereof; —determining the changes of expression of the at least two genes screened by the gene expression profile (2) in comparison with healthy tissue or with an early stage tumor; and—identifying the therapeutical target as a hemostatic factor, being upregulated or down-regulated. | 01-14-2010 |
Gabriela Salinse-Ricater, Göttingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20090221444 | Method for Identifying, Marking and Treating Epithelial Lung Tumour Cells and Means for Carrying Out Said Method - The bronchial carcinoma is the most common tumour found in humans world-wide and is in most cases beyond remedy. The invention relates to a method for identifying, marking and treating epithelial lung tumour cells, specifically of an adenocarcinoma, with the aid of novel treatment targets, and to means for carrying out said method. At the basis of the invention is the discovery that the expression of genes that code for CAM and ECM molecules is modified in c-raf and/or c-myc induced adenocarcinomas of the lung. Cell-adhesion proteins and extra-cellular matrix proteins constitute the treatment targets. According to the invention, a biological or biotechnological system is brought into contact with a dissolved substance that has an affinity to at least one of the following genes: ADAM19, Mmp12, Col18a1, Col15a1, CD44, Bsg, Itgb2, Itgax, Lamc2, Lamb3, Alcam, Cldn2, Cldn3, Cldn7, Krt1-18, Krt2-8, tacstd1, tacstd2, S100a1, S100a11, their variants, parts of said genes, their mRNA or their gene products, cleavage products derived from said genes, polypeptides or peptides, said substance being bound to a suitable marker. | 09-03-2009 |
Gabriela Salinse-Ricater, Göttingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20090221444 | Method for Identifying, Marking and Treating Epithelial Lung Tumour Cells and Means for Carrying Out Said Method - The bronchial carcinoma is the most common tumour found in humans world-wide and is in most cases beyond remedy. The invention relates to a method for identifying, marking and treating epithelial lung tumour cells, specifically of an adenocarcinoma, with the aid of novel treatment targets, and to means for carrying out said method. At the basis of the invention is the discovery that the expression of genes that code for CAM and ECM molecules is modified in c-raf and/or c-myc induced adenocarcinomas of the lung. Cell-adhesion proteins and extra-cellular matrix proteins constitute the treatment targets. According to the invention, a biological or biotechnological system is brought into contact with a dissolved substance that has an affinity to at least one of the following genes: ADAM19, Mmp12, Col18a1, Col15a1, CD44, Bsg, Itgb2, Itgax, Lamc2, Lamb3, Alcam, Cldn2, Cldn3, Cldn7, Krt1-18, Krt2-8, tacstd1, tacstd2, S100a1, S100a11, their variants, parts of said genes, their mRNA or their gene products, cleavage products derived from said genes, polypeptides or peptides, said substance being bound to a suitable marker. | 09-03-2009 |
Gabriela Stroian, Verdun CA
| Patent application number | Description | Published |
|---|---|---|
| 20080298540 | DEFORMABLE PHANTOM APPARATUS - A deformable phantom apparatus for simulating motion of a patient's anatomy in 3D during breathing, the apparatus comprising a chamber fillable with a first fluid, a deformable member comprising tissue equivalent material of the anatomy being simulated, the deformable member being positionable within the chamber in the first fluid and having an open end in fluid communication with a second fluid outside the chamber in use; and a mechanism for causing the second fluid to flow through the open end to deform the deformable member between a normal state and a deformed state to simulate motion during breathing. | 12-04-2008 |
Gabriela Surpi, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110131164 | SYSTEM AND METHOD FOR BUILDING A PREDICTIVE SCORE WITHOUT MODEL TRAINING - A system and method for building a predictive score without model training are disclosed. A set of predictive variables is defined based on raw data fields generated from raw data from one or more sources and domain knowledge. The raw data includes a historical set of transactions previously generated by one or more raw data sources. An scaled relative risk table to describe each predictive variable of the set of predictive variables is generated. The set of predictive variables is combined based on their associated relative risk tables to generate a predictive score for a future set of transactions. | 06-02-2011 |
Gabriela Vaduva, Wildwood, MO US
| Patent application number | Description | Published |
|---|---|---|
| 20090100536 | Transgenic plants with enhanced agronomic traits - This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits. | 04-16-2009 |
| 20110195175 | TRANSGENIC HIGH TRYPTOPHAN PLANTS - The present invention provides a method for altering the tryptophan content of a plant by introducing and expressing an isolated DNA segment encoding an anthranilate synthase in the cells of the plant. Transgenic plants transformed with an isolated DNA segment encoding an anthranilate synthase, as well as human or animal food, seeds and progeny derived from these plants, are also provided. | 08-11-2011 |
| 20110258734 | GENE SEQUENCES AND USES THEREOF IN PLANTS - This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits. | 10-20-2011 |
Gabriela Vincze, Aveiro PT
| Patent application number | Description | Published |
|---|---|---|
| 20110114227 | GRAIN REFINEMENT OF METALLIC COMPONENTS BY CONTROLLED STRAIN PATH CHANGE - Nowadays, the production of metallic parts, namely sheet metal, with high strength and formability, represents a big challenge for automotive, aerospace and assembling industries. The present invention deals with a new plastic deformation process that allows, by controlling the strain path change, the production of sheet metals with a grain size of 1-2 micron and, consequently, with a yield stress 3-4 times than the ones obtained with conventional processes, keeping the same formability. The process is easy for industrialization and its optimization requires only two fundamental parameters that characterize the ratio of thickness reduction, shear strain and amplitude in the change of strain path. | 05-19-2011 |
Gabriela Voskerician, Beachwood, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20100082113 | TISSUE REPAIR IMPLANT - Described herein are tissue repair implants that include a first or lower layer of peritoneal membrane and a support member. The implants can further include an upper layer of peritoneal membrane, and the support member can reinforce the two layers of peritoneal membrane. For example, the support member can be located between the lower layer of peritoneal membrane and the upper layer of peritoneal membrane. The support member can be encapsulated between the two layers of peritoneal membrane to attach the two layers of peritoneal membrane to the support member. The support member can be made from a non-biological synthetic material mesh with a plurality of openings extending therethrough. Either of the layers of peritoneal membrane and/or the support member may be attached to a wall (e.g., an interior wall) of an abdominal tissue. Either of the layers of peritoneal membrane may be remodelled by in-growth of tissue. | 04-01-2010 |
| 20100082114 | TISSUE REPAIR IMPLANT - Described herein are tissue repair implants comprising at least a first layer of peritoneal membrane. The first layer of peritoneal membrane can be located adjacent to a second layer of peritoneal membrane and can be in direct contact with the second layer of peritoneal membrane. Additional layers (e.g., a third or fourth layer) can be included. Where more than one layer is present, the layers can be affixed to one another. For example, a first layer of peritoneal membrane can be attached to the second layer of peritoneal membrane by an adhesive bond, suture, or staple. One or more of the peritoneal membranes can be non-crosslinked, partially crosslinked, or substantially fully crosslinked. Any of the layers of peritoneal membrane may be attached to a wall (e.g., an interior or exterior wall) of an abdominal tissue by an adhesive, suture, and/or staples. | 04-01-2010 |
Gabriela Wis-Surel, Cos Cob, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090062169 | Iridescent soap bars containing ethoxylated alcohols - An iridescent continuous phase soap bar with an ordered layered microstructure containing soap, water and specific ethoxylated alcohols is described. The phenomena of continuous phase iridescence in a soap bar is characterised as blue hue which intensity depends on the viewing angle and on the background color used for its observation by the user. In a preferred embodiment, the iridescent soap bar is prepared with mixing equipment capable of creating intensive mass shearing conditions and which generate high compression and extensional forces on the processed soap mass. | 03-05-2009 |