Froehner
Klaus Froehner, Stuhr DE
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20110006874 | MICROMECHANICAL ACTUATOR - A micromechanical actuator includes a movable first spring element having metal and/or silicon. The first spring element is fitted at a first point and can move freely at a second point. A second spring element connected to the first spring element has silicon and is partially arranged on an electrically insulating material which is applied to a substrate. The second spring element is arranged at a distance from the substrate above the substrate on a first plane, and the first spring element is arranged above the second spring element on a second plane which is at a distance from the first plane such that the first and second spring elements can move with respect to the substrate. The actuator has a third spring element which is mechanically coupled to the first spring element. The elastic deformation of the second spring element can be induced by a length change of the third spring element. | 01-13-2011 |
Stefanie Froehner, Muenchen DE
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20130065792 | INDUCIBLE EXPRESSION OF SGLT5, METHODS AND KITS USING THE SAME - The present invention pertains to the function of SGLT5 as a sodium dependent co-transporter of mannose and/or fructose. The invention provides nucleic acids and host cells for inducible expression of SGLT5. Based on an inducible expression system the invention provides methods, assays and test kits for the identification of compounds interacting with SGLT5, especially with human SGLT5. | 03-14-2013 |
Stefanie Froehner, Penzberg DE
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20140017682 | HIGH RESOLUTION MELTING ANALYSIS AS A PRESCREENING TOOL - Compositions and methods for determining an increased likelihood of a response to a targeted treatment of a cancer disease including isolating genomic DNA from a patient sample, amplifying a fragment of DNA by means of PCR with a specific pair of amplification primers, determining if the amplified fragment comprises a wildtype sequence or a mutation by means of a High Resolution Melting Analysis (HRM), and correlating the presence or absence of a mutation with an increased likelihood of success of said targeted treatment. Respective primer pairs, compositions and kits are also claimed. | 01-16-2014 |
20140170650 | Primers with Modified Phosphate and Base in Allele-Specific PCR - The present invention includes a method of allele-specific amplification, utilizing an allele-specific oligonucleotide, at least partially complementary to more than one variant of the target sequence, but having at least one selective nucleotide complementary to only one variant of the target sequence and incorporating both a nucleotide with a base covalently modified at the exocyclic amino group and a modified phosphate. | 06-19-2014 |
20150024429 | METHOD AND DEVICE FOR THE HOMOGENEOUS DISTRIBUTION OF SUSPENDED CELL COMPONENTS - A method for the homogeneous distribution of cell components suspended in a liquid on a surface and a device for the implementation thereof. | 01-22-2015 |
20150152510 | HIGH RESOLUTION MELTING ANALYSIS AS A PRESCREENING TOOL - Compositions and methods for determining an increased likelihood of a response to a targeted treatment of a cancer disease including isolating genomic DNA from a patient sample, amplifying a fragment of DNA by means of PCR with a specific pair of amplification primers, determining if the amplified fragment comprises a wildtype sequence or a mutation by means of a High Resolution Melting Analysis (HRM), and correlating the presence or absence of a mutation with an increased likelihood of success of said targeted treatment. Respective primer pairs, compositions and kits are also claimed. | 06-04-2015 |
Stephanie Froehner, Penzberg DE
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20150079600 | Application of Oligo-DT Molecules To Avoid Generation of High Molecular PCR Products Induced By Poly-A Carrier - During RNA isolation carrier nucleic acids such as polyA-RNA are used in order to increase the yield of the isolated RNA. The carrier nucleic acids may lead to high molecular weight products which may interfere in subsequent steps, such as reverse transcription, PCR and gel electrophoresis. The present invention therefore refers to a method and a kit for reverse transcription and the use of a blocking nucleic acid molecule for blocking the carrier polyA-RNA. | 03-19-2015 |
Thomas Froehner, Karlsruhe DE
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20150059703 | MULTIPART INSULATING ELEMENT, IN PARTICULAR FOR A FUEL INJECTION DEVICE - An insulating element for a fuel injection apparatus is notable in particular for the fact that a low-noise design is achieved. The fuel injection apparatus encompasses at least one fuel injection valve and one receiving bore in a cylinder head for the fuel injection valve, and the insulating element between a valve housing of the fuel injection valve and a wall of the receiving bore. The insulating element possesses an inner insulating ring that is present in encapsulated fashion between an outer ring and an inner ring. The outer ring is directed toward the fuel injection valve and the inner ring is directed toward the wall of the receiving bore, so that corresponding abutment of these components occurs with the insulating element in the installed state. The fuel injection apparatus is suitable in particular for direct injection of fuel into a combustion chamber of a mixture-compressing spark-ignited internal combustion engine. | 03-05-2015 |
Wiebke Froehner, Amberg DE
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20160044094 | METHOD, CONFIGURATION, USE OF THE METHOD AND COMPUTER PROGRAM PRODUCT FOR EVALUATING ENERGY ENGINEERING DATA - A method evaluates power engineering data using a data request that is transmitted to a coupling device by a first communication link. The coupling device is used to convert the data request from a coupling data format into a further data request that is specific to an energy engineering device in a device-specific data format. The further data request is transmitted to the power engineering device by a second communication link. The power engineering device transmits its power engineering data, requested by the further data request, to the coupling device by the second communication link. The power engineering data are in a data format that is specific to the power engineering device, and the coupling device converts all the power engineering data requested by further data requests into a data response in the coupling data format and uses the first communication link to transmit them to the evaluation device. | 02-11-2016 |