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Friedman, NY
Adam Friedman, Manhattan, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110250134 | SUSTAINED RELEASE NITRIC OXIDE FROM LONG LIVED CIRCULATING NANOPARTICLES - The invention provides methods for delivering a NO molecule or precursor thereof to a vascular compartment of a subject comprising: administering to the subject, a NO particle formulation, via an intravascular, intraperitoneal, or intramuscular administration, in an amount sufficient to induce vascular smooth muscle relaxation thereby delivering the NO molecule or precursor thereof to the vascular compartment of the subject, wherein the NO particle formulation comprises NO attached to a nanoparticle or microparticle. | 10-13-2011 |
Adam Friedman, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090297634 | Compositions for sustrained release of nitric oxide, methods of preparing same and uses thereof - The invention provides compositions for releasing nitric oxide (NO) comprising a matrix that encapsulates nitric oxide. Nitric oxide is released when the composition is exposed to an aqueous environment. The invention further provides methods of preparing the compositions and uses of the compositions for treating infections and disorders. | 12-03-2009 |
| 20110135742 | CONTROLLED RELEASE ENCAPSULATED ANTI-BACTERIAL AND ANTI-INFLAMMATORY NANOPARTICLES - This invention pertains to the formulation of nanoparticles that have intrinsic antimicrobial and anti-inflammatory activity. The nanoparticles can be impregnated with one or more therapeutic agents and thereby enhance the antimicrobial and/or anti-inflammatory activity of such agents, and also other properties that the therapeutic agents provide. | 06-09-2011 |
Arial Friedman, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100023374 | Providing Tailored Messaging to Customers - A tailored messaging capability (also referred to as customized messaging) delivers individually relevant or individualized spend recommendations regarding merchants to cardholders at a level of granularity not previously available. This capability brings together the cardholder and the merchant environments to support a spend-centric revenue model. Based on a cardholder's spending history, this tool provides relevant merchant recommendations to the individual cardholder based on that cardholder's unique spend potential in view of that of their peer group. This capability encourages business spend in categories which have historically been paid by invoice, cash, or check. By highlighting relevant merchants, not only is perception of coverage shifted, but specific spend behavior is influenced. | 01-28-2010 |
Carol Friedman, Larchmont, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100004874 | GENE DISCOVERY THROUGH COMPARISONS OF NETWORKS OF STRUCTURAL AND FUNCTIONAL RELATIONSHIPS AMONG KNOWN GENES AND PROTEINS - The present invention also relates to natural language processing and extraction of relational information associated with genes and proteins that are found in genomics journal articles. To enable access to information in textual form, the natural language processing system of the present invention provides systems and methods for extracting and structuring information found in the literature in a form appropriate for subsequent applications. | 01-07-2010 |
Carol Friedman, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100010804 | METHODS AND SYSTEMS FOR EXTRACTING PHENOTYPIC INFORMATION FROM THE LITERATURE VIA NATURAL LANGUAGE PROCESSING - Systems and methods for extracting and encoding genotype-phenotype information from journal articles and other publications are provided. In some embodiments, the disclosed subject matter includes a preprocessor, boundary identifier, parser, phrase recognizer and an encoder to convert natural-language input text and parameters into structured text. The structured text can take the form of codes which account for genotype-phenotype information and are compatible with a controlled vocabulary. | 01-14-2010 |
Carola Friedman, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100120867 | METHOD OF TREATMENT - Improvements in the treatment of patients suffering from frequent heartburn are provided by a treatment regimen comprising administration of an effective daily amount of lansoprazole or a pharmaceutically acceptable salt thereof for up to 14 days. | 05-13-2010 |
Daniel Friedman, Sleepy Hollow, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090206952 | DELAY LINE REGULATION USING HIGH-FREQUENCY MICRO-REGULATORS - A regulated delay line device includes main regulator coupled to a node, and a plurality of delay branches coupled to the node to receive a voltage output to the node by the main regulator. Each of the plurality of delay branches includes a micro-regulator and a delay line. The delay line is coupled to the micro-regulator such that unfiltered noise is removed locally at each delay branch by a corresponding micro-regulator. | 08-20-2009 |
Daniel B. Friedman, Dewitt, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090158673 | ADAPTABLE ROOF SYSTEM - There is set forth a retractable roof system of a specified arrangement including a first elongated track and a second elongated track, and a beam extending between the first elongated track and the second elongated track. The beam is described as supporting a cover. There is also set forth apparatus for moving the beam in relation to the first elongated track and the second elongated track. | 06-25-2009 |
Daniel J. Friedman, Yorktown Heights, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100328130 | TIME-TO-DIGITAL BASED ANALOG-TO-DIGITAL CONVERTER ARCHITECTURE - Apparatus and methods are provided relating to time-to-digital based analog-to-digital converter. An apparatus includes a time-to-digital converter based analog-to-digital converter for generating a first signal and a second signal having a timing relationship between a rising edge of the first signal and a rising edge of the second signal based on a sampled input analog voltage level, and converting the timing relationship into a corresponding time-to-digital representation. The time-to-digital representation is obtained without any voltage comparison and current comparison. | 12-30-2010 |
| 20110063038 | ULTRA-COMPACT PLL WITH WIDE TUNING RANGE AND LOW NOISE - A design for an oscillator, and a PLL incorporating such an oscillator, which takes up little physical area but maintains a large tuning range and low phase noise. Two LC-tanks are nested and switched. Through tuning the inactive tank, the range of the active tank may be increased and finer tuning becomes possible. | 03-17-2011 |
| 20110106741 | SYSTEM FOR ADDRESS-EVENT-REPRESENTATION NETWORK SIMULATION - A system, method, and design structure for address-event-representation network simulation are provided. The system includes a hardware structure with a plurality of interconnected processing modules configured to simulate a plurality of interconnected nodes. To simulate each node, the hardware structure includes a source table configured to receive an input message and identify a weight associated with a source of the input message. The hardware structure also includes state management logic configured to update a node state as a function of the identified weight, and generate an output signal responsive to the updated node state. The hardware structure further includes a target table configured to generate an output message in response to the output signal, identify a target to receive the output message, and transmit the output message. The hardware structure may further include learning logic configured to combine information about input messages and generated output signals, and to update weights. | 05-05-2011 |
Daniel Joseph Friedman, Sleepy Hollow, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090195275 | TECHNIQUE FOR EFFICIENTLY MANAGING BOTH SHORT-TERM AND LONG-TERM FREQUENCY ADJUSTMENTS OF AN ELECTRONIC CIRCUIT CLOCK SIGNAL - A control system for generating an electronic circuit clock signal that can optimize operating frequency margins by responding to short term effects by quickly varying the clock frequency and long term effects by finding an optimal frequency point. A sensor indicates frequency margins associated with safe use of the clock signal, and these frequency margins are input into a frequency compensator and used to determine whether the system is operating within acceptable margins, or alternatively to modify the operating clock frequency on a short-term basis in order to achieve acceptable operating margins. The requests for frequency adjustment by the frequency compensator are provided to a frequency filter, which combines such request with a maintained/accumulated history of previous short-term frequency requests that have previously been made in order to determine whether an update needs to be made to the target frequency to provide long-term frequency control. | 08-06-2009 |
| 20090195278 | METHOD AND CIRCUIT FOR CONTROLLING CLOCK FREQUENCY OF AN ELECTRONIC CIRCUIT WITH NOISE MITIGATION - A technique to mitigate noise spikes in an electronic circuit device such as an integrated circuit. The clock frequency of a clock signal used by the electronic circuit is controlled such that instantaneously large changes to the clock frequency are avoided by use of a frequency filter that is capable of generating frequency ramps having a linear slope which is used as a feedback signal in a digital phase-locked loop clock circuit in lieu of a discrete, stair-stepped feedback control signal. | 08-06-2009 |
Daniel Joseph Friedman, Yorktown Heights, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110309888 | TECHNIQUE FOR LINEARIZING THE VOLTAGE-TO-FREQUENCY RESPONSE OF A VCO - Apparatuses and methods are provided relating to a voltage controlled oscillator (VCO) based on current starved inverting delay stages; wherein in each stage a PMOS transistor as header and an NMOS transistor as footer are used with their gate-to-source voltages always equal to analog control voltage. The analog control voltage is also used as the supply voltage of the oscillator. An exemplary apparatus includes a VCO of n stages, where n is an odd number and where each stage includes a current starved inverter where the analog control voltage is also used as the supply voltage of each delay stage. | 12-22-2011 |
David Friedman, Monroe, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110198895 | Portable beach chair cover - A beach chair cover has a slip-over pouch which slides over the upper portion of a beach or lounge chair, with a lower portion that affixes to a beach chair. The cover has pockets hanging off of its sides, to hold various objects. The pockets can be open, or closable via a fastening device, with fold over flap. Underneath the cover's lower portion is a hidden pouch, securable via a small lock, or otherwise. The pouch, invisible to passers-by, can hold wallets, cash, or other items. The cover can have a series of sewn-in loops, e.g., on its sides, which can hold a wire for earphones or a small speaker. The beach chair cover can be folded up into a slip-over pouch, and carried by means of an integrated handle. | 08-18-2011 |
David Friedman, Lawrence, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090290141 | Matched pairs of gemstones - A system is provided for certifying two or more gemstones as being a matched pair. The system includes measuring values for at least four physical properties of a multiplicity of gemstones, identifying a first gemstone, a second gemstone, and optionally still further gemstones all being within match tolerances of the respective measured values, and certifying in a single certificate that based on the match tolerances, the gemstones constitute a matched set. Also disclosed is jewelry and a process for creating jewelry based on the certification system. | 11-26-2009 |
Eby G. Friedman, Rochester, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090150847 | Logic circuit delay optimization - A method for modifying a logic circuit layout to optimize circuit propagation delays for improved circuit operation is presented. The layout includes multiple logic gates connected by conductive segments. An initial layout of a physical electronic logic circuit having the plurality of logic gates is input. A respective size is determined for each of the logic gates in accordance with the initial layout and a circuit propagation delay criterion. The circuit propagation delay criterion is a joint function of properties of at least some of the logic gates and at least some of the conductive segments. A modified logic circuit layout is output. The modified logic circuit layout includes a layout of the logic gates arranged in accordance with the initial layout, where each of the logic gates is modified according to the respective determined size, thereby to obtain a modification of the logic circuit layout incorporating an optimized circuit propagation delay. | 06-11-2009 |
Jack P. Friedman, Schenectady, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080232578 | ETHERNET VOLTAGE SOURCE APPARATUS AND METHOD - An Ethernet voltage source apparatus and method. The apparatus includes an electrical connector, a receiving circuit electrically connected to the Ethernet cable connector, a voltage regulator/power conditioning circuit electrically connected to the receiving circuit, and a first interface output connector electrically connected to the voltage regulator/power conditioning circuit. The receiving circuit receives a first voltage signal and an Ethernet data signal from the Ethernet cable. The receiving circuit separates the first voltage signal from the Ethernet data signal. The voltage regulator/power conditioning circuit generates a second voltage signal from the first voltage signal. The second voltage signal is configured as a first power source for an industrial/commercial device. The first interface output connector is configured to electrically connect the second voltage signal to the industrial/commercial device. | 09-25-2008 |
| 20080290729 | ETHERNET INTERCONNECTION APPARATUS AND METHOD - An Ethernet interconnection device and method. The apparatus includes an input Ethernet connector, a signal separating circuit electrically connected to the input Ethernet connector, a voltage regulator circuit electrically connected to the signal separating circuit, an Ethernet signal repeater circuit electrically connected to the signal separating circuit, and an output Ethernet connector electrically connected to the Ethernet signal repeater circuit. The receiving circuit receives a first voltage signal and an Ethernet data signal from an Ethernet cable. The signal separating circuit separates the first voltage signal from the Ethernet data signal. The voltage regulator conditioning circuit generates a second voltage signal from the first voltage signal. The second voltage signal is a power source the Ethernet signal repeater circuit. The output Ethernet connector is configured to electrically conduct an regenerated Ethernet data signal from the Ethernet signal repeater circuit to an industrial/commercial device. | 11-27-2008 |
Jacob W. Friedman, Poughkeepsie, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100174873 | Priority Promotion for Service Requests - A method for priority promotion of a service request comprises receiving the service request for a target address space into a set of work requests, the set of work requests comprising a plurality of service requests for the target address space, the service request originating from a source address space, the service request having a priority equivalent to a priority of the target address space, the source address space having a higher priority than the target address space; determining a number of service requests for the target address space in the set of work requests; and, in the event the number of service requests for the target address space exceeds a predetermined value, promoting the priority of the service request to the priority of the source address space. | 07-08-2010 |
Jeanne V. Friedman, Rye, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100189761 | Methods for Prevention and/or Treatment of Capsular Contracture - Methods for prevention or treatment of capsular contracture following surgical implants and other fibrosis related conditions comprising applying a topical composition comprising a pharmaceutically acceptable keratolytic, a pharmaceutically acceptable protein denaturant, a hydrating agent, and combinations thereof are disclosed. | 07-29-2010 |
Jeffrey Friedman, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110263495 | METHODS AND KITS FOR TREATING DISEASE BY ADMINISTERING INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-2 - The present invention is directed to methods of treating Type I diabetes by administering a therapeutically effective amount of an Insulin-like Growth Factor-binding protein-2. The present invention is also directed to methods treating Type 2 diabetes comprising the step of administering a therapeutically effective amount of Insulin-like Growth Factor-binding protein-2. The present invention is further directed to methods treating insulin resistance comprising the step of administering a therapeutically effective amount of Insulin-like Growth Factor-binding protein-2. The present invention is directed to methods of treating hepatic steatosis by administering a therapeutically effective amount of an Insulin-like Growth Factor-binding protein-2. The present invention is also directed to methods lowering blood glucose and serum insulin in non-diabetic subjects comprising the step of administering a therapeutically effective amount of Insulin-like Growth Factor-binding protein-2. | 10-27-2011 |
Jeffrey C. Friedman, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090292611 | SYSTEM AND METHOD FOR TARGETING ADVERTISEMENTS TO TENANTS IN A BUILDING - A system and method for targeting advertisements to tenants in a building by providing a portal for a building accessible via the Internet with the portal based upon the specific needs of targeted advertising in the building. Advertisements are received from a user of the portal and the advertisements are distributed to a target audience in the building that is determined based upon historical transaction data for the building. A user is provided with the historical transaction data of previous transactions by tenants in the building. The portal is designed to suit the specific needs of a building. | 11-26-2009 |
Jeffrey M. Friedman, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090318677 | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof - The present invention relates generally to the control of body weight of animals including mammals and humans, and more particularly to materials identified herein as modulators of weight, and to the diagnostic and therapeutic uses to which such modulators may be put. In its broadest aspect, the present invention relates to the elucidation and discovery of nucleotide sequences, and proteins putatively expressed by such nucleotides or degenerate variations thereof, that demonstrate the ability to participate in the control of mammalian body weight. The nucleotide sequences in object represent the genes corresponding to the murine and human ob gene, that have been postulated to play a critical role in the regulation of body weight and adiposity. Preliminary data, presented herein, suggests that the polypeptide product of the gene in question functions as a hormone. The present invention further provides nucleic acid molecules for use as molecular probes, or as primers for polymerase chain reaction (PCR) amplification, i.e., synthetic or natural oligonucleotides. In further aspects, the present invention provides a cloning vector, which comprises the nucleic acids of the invention; and a bacterial, insect, or a mammalian expression vector, which comprises the nucleic acid molecules of the invention, operatively associated with an expression control sequence. Accordingly, the invention further relates to a bacterial cell or a mammalian transfected or transformed with an appropriate expression vector, and correspondingly, to the use of the above mentioned constructs in the preparation of the modulators of the invention. Also provided are antibodies to the ob polypeptide. Moreover, a method for modulating body weight of a mammal is provided. In specific examples, genes encoding two isoforms of both the murine and human ob polypeptides are provided. | 12-24-2009 |
| 20110218332 | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof - The present invention relates generally to the control of body weight of animals including mammals and humans, and more particularly to materials identified herein as modulators of weight, and to the diagnostic and therapeutic uses to which such modulators may be put. In its broadest aspect, the present invention relates to the elucidation and discovery of nucleotide sequences, and proteins putatively expressed by such nucleotides or degenerate variations thereof, that demonstrate the ability to participate in the control of mammalian body weight. The nucleotide sequences in object represent the genes corresponding to the murine and human ob gene, that have been postulated to play a critical role in the regulation of body weight and adiposity. Preliminary data, presented herein, suggests that the polypeptide product of the gene in question function as a hormone. The present invention further provides nucleic acid molecules for use as molecular probes, or as primers for polymerase chain reaction (PCR) amplification, i.e., synthetic or natural oligonucleotides. In further aspects, the present invention provides a cloning vector, which comprises the nucleic acids of the invention; and a bacterial, insect, or a mammalian expression vector, which comprises the nucleic acid molecules of the invention, operatively associated with an expression control sequence. Accordingly, the invention further relates to a bacterial or a mammalian cell transfected or transformed with an appropriate expression vector, and correspondingly, to the use of the above mentioned constructs in the preparation of the modulators of the invention. Also provided are antibodies to the ob polypeptide. Moreover, a method for modulating body weight of a mammal is provided. In specific examples, genes encoding two isoforms of both the murine and human ob polypeptides are provided. | 09-08-2011 |
Mark J. Friedman, Niskayuna, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110193396 | LOCKING HARNESS APPARATUS AND METHOD - A harness apparatus including a first adjustable harness strap, a second adjustable harness strap, and a retainer apparatus. The retainer apparatus includes a first retainer portion slidably attached to the first harness strap, a second retainer portion slidably attached to the second harness strap, and a braking mechanism configured to prevent the first retainer portion and the second retainer portion from moving along the first harness strap and the second harness strap. The first retainer portion is removably attached to the second retainer portion. The braking mechanism includes a braking device configured to apply resistance to the first harness strap and/or the second harness strap and to hold the retainer apparatus in a stationary position along the first harness strap and the second harness strap. | 08-11-2011 |
Michael L. Friedman, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20120088082 | Thermoplastic Multilayer Interlayer Polymer Film and Related Glass Laminate Composite Including Same - A multilayer interlayer polymer film and a high clarity safety glass laminate made using the same include: (1) a core layer comprising one of an ionomer polymer material and a thermoplastic polyurethane polymer material; (2) at least one intermediate layer laminated to the core layer and comprising the other of the ionomer polymer material and the thermoplastic polyurethane polymer material; and (3) at least one skin layer laminated to the at least one intermediate layer and comprising a non-ionomer polyolefin polymer material. The multilayer interlayer polymer film provides the high clarity safety glass laminate with enhanced performance with respect to optical properties and manufacturability. In an alternative embodiment the at least one skin layer may be omitted when the intermediate layer comprises a thermoplastic polyurethane material with adequate adhesion to glass. | 04-12-2012 |
| 20120088101 | MULTILAYER INTERLAYER POLYMER FILM FOR FIRE-SCREEN GLAZINGS AND RELATED FIRE-SCREEN PRODUCTS - A multilayer interlayer polymer film for use within and a high clarity and high efficiency fire-screen glazing or related fire-screen product uses a particular ordering of layers. The ordering of layers includes: (1) a core layer comprising one of a sulfur containing thermoplastic polymer material and a fluorine containing thermoplastic polymer material; (2) at least one intermediate layer laminated to the core layer and comprising the other of the sulfur containing thermoplastic polymer material and the fluorine containing thermoplastic polymer material; and (3) at least one skin layer laminated to the at least one intermediate layer and comprising a thermoplastic polyurethane material. The film provides cost effective and efficient fire-screen glazings and related fire-screen products due to the thermoplastic polyurethane polymer material and the sulfur containing thermoplastic polymer materials which also may be used in absence of the fluorine containing thermoplastic polymer material to provide an additional embodiment. | 04-12-2012 |
Milton Friedman, Cedarhurst, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110210018 | Combination Cell Phone and Eyeglass Dedicated Case - A trim, compact combination case dedicated to storing a cell phone (or PDA or other small electronic device) and an accessible pair of eyeglasses is disclosed. The combination cell phone and eyeglass case includes a phone housing compartment and an adjacent eyeglass housing compartment, which are configured to hold the juxtaposed cell phone and eyeglasses. The phone housing compartment and the eyeglass housing compartment are permanently attached by a joining mechanism. An optional eyeglass-housing cap and an optional swivel belt clip are also disclosed. The compact design allows the combination case to be easily carried in a bag, purse, briefcase or pocket. The combination case advantageously positions the eyeglasses oriented and located for quick retrieval when needed to view the phone screen or buttons. | 09-01-2011 |
| 20110303560 | Combination Cell Phone and Eyeglass Dedicated Case - A trim, compact combination case dedicated to storing a cell phone (or PDA or other small electronic device) and an accessible pair of eyeglasses is disclosed. The combination cell phone and eyeglass case includes only a phone housing compartment and an adjacent eyeglass housing compartment, which are configured to hold the cell phone and eyeglasses side by side. An optional eyeglass-housing cap and an optional swivel belt clip are also disclosed. The compact design allows the combination case to be easily carried in a bag, purse, briefcase or pocket. The combination case advantageously positions the eyeglasses oriented and located for quick retrieval when needed to view the phone screen or buttons. | 12-15-2011 |
Rivka T Friedman, Cedarhurst, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110210018 | Combination Cell Phone and Eyeglass Dedicated Case - A trim, compact combination case dedicated to storing a cell phone (or PDA or other small electronic device) and an accessible pair of eyeglasses is disclosed. The combination cell phone and eyeglass case includes a phone housing compartment and an adjacent eyeglass housing compartment, which are configured to hold the juxtaposed cell phone and eyeglasses. The phone housing compartment and the eyeglass housing compartment are permanently attached by a joining mechanism. An optional eyeglass-housing cap and an optional swivel belt clip are also disclosed. The compact design allows the combination case to be easily carried in a bag, purse, briefcase or pocket. The combination case advantageously positions the eyeglasses oriented and located for quick retrieval when needed to view the phone screen or buttons. | 09-01-2011 |
Robert E. Friedman, Brooklyn,, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090080202 | TRACK LIGHTING CONSTRUCTION - A track lighting system comprises an extruded track body, having adjacent first and a second track sections; a defined entrance to the track body that is common to both the first and the second track sections, a respective conductive member connectable to an electrical power source disposed at a bottom of each of the first and the second track sections so as to form two independent circuits within the extruded track body; and a separating wall positioned between the first track and the second track. The system further comprises a light fixture insertable through the entrance so as to make electrical connection with one of the conductive members, the fixture comprising: a socket housing a stem connecting the socket housing to a transformer housing containing an electrical circuit having an output transformer; a lamp in electrical connection with the output transformer by wires within the stem; and the transformer housing including a wall having first and second contact slots formed therein. | 03-26-2009 |
Scott Friedman, Scarsdale, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090325150 | KLF6 ALTERNATIVE SPLICE FORMS AND A GERMLINE KLF6 DNA POLYMORPHISM ASSOCIATED WITH INCREASED CANCER RISK - Disclosed are methods of identifying and diagnosing certain types of cancers and pre-stages thereof in a patient by identifying alternatively spliced isoforms of wild type KLF6 (KLFwt), in particular anyone of the isoforms selected from the group consisting of: KLF6 splice variant-1 (KLF6SV1), KLF6 splice variant-2 (KLF6SV2), and KLF6 splice variant-3 (KLF6SV3). Also disclosed are methods diagnosing cancer using the polypeptides and polynucleotides identified herein, as well as methods of treating certain types of cancers by inhibiting polynucleotides and polypeptides identified herein. | 12-31-2009 |
| 20100104540 | METHODS AND COMPOSITIONS FOR TREATMENT OF FIBROSIS - Treatment methods and compositions for the treatment of fibrosis are provided. In some embodiments, these methods include augmentation of dendritic cells for treatment of fibrosis. In some embodiments, fms-like tyrosine kinase 3 ligand (Flt3L) is used for the treatment of fibrosis and/or the augmentation of dendritic cells. In certain embodiments, the invention relates to methods for the treatment of fibrosis using Flt3L-expanded dendritic cells. In certain embodiments, the fibrosis is hepatic or pulmonary fibrosis. | 04-29-2010 |
| 20110059899 | Kruppel-like factor 6 (KLF6), a tumor suppressor protein, and diagnostics, therapeutics, and screening based on this protein - The present invention relates to identification of tumor suppressor activity of a protein, KLF6 (KLF6), and to related diagnostic and therapeutic compositions and methods. The discovery of this tumor suppressor activity provides screening targets as well, particularly screening for compounds that overcome gene inactivation or alteration. | 03-10-2011 |
Solomon Friedman, Brooklyn, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090049528 | SYSTEM, METHOD AND APPARATUS FOR ESTABLISHING PRIVACY IN INTERNET TRANSACTIONS AND COMMUNICATIONS - A system for conducting a transaction with privacy on a wide area network, the system including a personal access device (PAD) associated with a subscriber to the system, the PAD storing a profile of the subscriber and generating commands, a privacy service provider (PSP) connected to the wide area network, the PAD being accessible by the PSP under first conditions set by the profile and the PSP being responsive to the commands from the PAD, a registered vendor (RV) connected to the wide area network, and a privacy shield network (PSN) connected to the wide area network, the RV being registered with the PSN and the PSN being structured to carry communications between the PSP and the RV related to the transaction under second conditions set by the profile. Advantageously, the PAD stores private data associated with the subscriber, and the PSP releases any of the private data to the RV only under the first and second conditions. | 02-19-2009 |