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Friedman, MA
Arnon Friedman, Marlboro, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090290620 | SYSTEMS AND METHODS FOR IMPLEMENTING RECEIVER TRANSPARENT Q-MODE - In a receiver transparent Q-mode, i.e., a Q-mode that is only implemented by a transmitter, the receiver is unaware of the Q-mode state of the transmitter. In this type of Q-mode configuration, the transmitter could enter and exit Q-mode as desired while the receiver, could, for example, continue to function as if operating normally, such as in “showtime.” Through this approach, it is not necessary for the receiver to detect the transmitter's entry and exit of Q-mode. | 11-26-2009 |
David J. Friedman, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120195902 | COMPOSITIONS AND METHODS FOR TREATING RENAL DISEASE - Compositions and methods are disclosed herein for treating or reducing the symptoms of a renal disease, such as focal segmental glomerulosclerosis (FSGS), hypertensive end-stage kidney disease (ESKD), and HIV-associated nephropathy (a distinct form of FSGS, also termed collapsing glomerulopathy). The compositions include the common variant of APOL1 and fragments thereof, as well as antibodies and fragments thereof that bind and neutralize pathogenic APOL1, nucleic acid molecules that encode the common variant of APOL1 and fragments thereof, and other compounds that bind and neutralize pathogenic APOL1. The methods of the invention include administering one or more of the compositions of the invention to a subject having or at risk of developing renal disease. | 08-02-2012 |
Edward Friedman, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100057353 | GPS Map for Commercial Vehicle Industry - GPS map for commercial vehicle industry comprising of a navigation system and user interface to optimize needed navigation for a commercial vehicle based on physical criteria and content taking into consideration low bridge clearances, load limits, one-way road designations, left-hand and dangerous turn restrictions, and allowances pertaining to commercial vehicles. Based on the specified dimension and content of the vehicle, the system will display roads on the map with alerting color, texture to warn driver about roads where location of the vehicle is prohibited. | 03-04-2010 |
| 20100057358 | PORTABLE GPS MAP DEVICE FOR COMMERCIAL VEHICLE INDUSTRY - Apparatus for determining a route for a road vehicle for a user comprising: | 03-04-2010 |
Gerald Martin Friedman, New Ipswich, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110012030 | EBEAM STERILIZATION APPARATUS - Improved electron beam sterilization apparatus and shielding techniques for use in are provided. A controller modulates an ebeam when sterilizing an interior to an object to ensure that adequate dose is received. Sterilization carousels are configured with input/discharge feeds to reduce the possibility of humans being exposed to dangerous levels of radiation. The system reduces the amount of shielding required to thereby lower cost of installation. | 01-20-2011 |
| 20110012032 | ELECTRON BEAM STERILIZATION APPARATUS - Improved electron beam sterilization apparatus and shielding techniques for use in are provided. A controller modulates an electron beam when sterilizing an interior to an object to ensure that adequate dose is received. Sterilization carousels are configured with input/discharge feeds to reduce the possibility of humans being exposed to dangerous levels of radiation. The system reduces the amount of shielding required to thereby lower cost of installation. | 01-20-2011 |
Joel Friedman, Andover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110071405 | Apparatus, Systems, and Methods of in-vivo Blood Clearing in a Lumen - In one aspect, the invention relates to a computer-implemented method of triggering optical coherence tomography data collection. The method includes collecting optical coherence tomography data with respect to a vessel using an optical coherence tomography probe disposed in the vessel; determining a clearing radius and a quality value for each frame of optical coherence tomography data collected for the vessel using a computer; determining if a blood clearing state has occurred using at least one clearing radius and at least one quality value; and generating a trigger signal in response to the blood clearing state. | 03-24-2011 |
Joel M. Friedman, Andover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090122320 | Imaging catheter with integrated reference reflector - In part, the invention relates to a lens assembly. The lens assembly includes a micro-lens; a beam director in optical communication with the micro-lens; and a substantially transparent film. The substantially transparent film is capable of bi-directionally transmitting light, and generating a controlled amount of backscatter. In addition, the film surrounds a portion of the beam director. | 05-14-2009 |
| 20110007315 | IMAGING CATHETER WITH INTEGRATED REFERENCE REFLECTOR - In part, the invention relates to a lens assembly. The lens assembly includes a micro-lens; a beam director in optical communication with the micro-lens; and a substantially transparent film. The substantially transparent film is capable of bi-directionally transmitting light, and generating a controlled amount of backscatter. In addition, the film surrounds a portion of the beam director. | 01-13-2011 |
| 20110071404 | Lumen Morphology and Vascular Resistance Measurements Data Collection Systems, Apparatus and Methods - A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed. | 03-24-2011 |
| 20120057157 | IMAGING CATHETER WITH INTEGRATED REFERENCE REFLECTOR - In part, the invention relates to a lens assembly. The lens assembly includes a micro-lens; a beam director in optical communication with the micro-lens; and a substantially transparent film. The substantially transparent film is capable of bi-directionally transmitting light, and generating a controlled amount of backscatter. In addition, the film surrounds a portion of the beam director. | 03-08-2012 |
| 20130010303 | Imaging Catheter With Integrated Reference Reflector - In part, the invention relates to a lens assembly. The lens assembly includes a micro-lens; a beam director in optical communication with the micro-lens; and a substantially transparent film. The substantially transparent film is capable of bi-directionally transmitting light, and generating a controlled amount of backscatter. In addition, the film surrounds a portion of the beam director. | 01-10-2013 |
Marc D. Friedman, Needham Heights, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110080559 | Ocular Imaging - A system for performing quasi-elastic light scattering and fluorescent ligand scanning on a subject's eye includes a light source configured to transmit light toward the subject's eye, a lens configured to focus light sent from the source and scattered by the subject's eye, a measurement reflector disposed to receive at least a portion of the focused light and configured to reflect a first portion of the received light, a camera configured and disposed to receive the first portion of the received light and configured to provide indicia of an image corresponding to the first portion of the received light, and a processor coupled to the camera and configured to analyze intensities of light in the image to determine a location of a reference point corresponding to an interface of a portion of the eye. | 04-07-2011 |
Marc D. Friedman, Needham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100290668 | LONG DISTANCE MULTIMODAL BIOMETRIC SYSTEM AND METHOD - A system for multimodal biometric identification has a first imaging system that detects one or more subjects in a first field of view, including a targeted subject having a first biometric characteristic and a second biometric characteristic; a second imaging system that captures a first image of the first biometric characteristic according to first photons, where the first biometric characteristic is positioned in a second field of view smaller than the first field of view, and the first image includes first data for biometric identification; a third imaging system that captures a second image of the second biometric characteristic according to second photons, where the second biometric characteristic is positioned in a third field of view which is smaller than the first and second fields of view, and the second image includes second data for biometric identification. At least one active illumination source emits the second photons. | 11-18-2010 |
| 20110118654 | Eye Therapy - Embodiments apply a cross-linking agent to a region of corneal tissue. The cross-linking agent improves the ability of the corneal tissue to resist undesired structural changes. For example, the cross-linking agent may be Riboflavin or Rose Bengal, and the initiating element may be photoactivating light, such as ultraviolet (UV) light. In these embodiments, the photoactivating light initiates cross-linking activity by irradiating the applied cross-linking agent to release reactive oxygen radicals in the corneal tissue. The cross-linking agent acts as a sensitizer to convert O | 05-19-2011 |
| 20110237999 | SYSTEMS AND METHODS FOR APPLYING AND MONITORING EYE THERAPY - Devices and approaches for activating cross-linking within corneal tissue to stabilize and strengthen the corneal tissue following an eye therapy treatment. A feedback system is provided to acquire measurements and pass feedback information to a controller. The feedback system may include an interferometer system, a corneal polarimetry system, or other configurations for monitoring cross-linking activity within the cornea. The controller is adapted to analyze the feedback information and adjust treatment to the eye based on the information. Aspects of the feedback system may also be used to monitor and diagnose features of the eye | 09-29-2011 |
| 20110285836 | Multimodal Ocular Biometric System - A multimodal biometric identification system captures and processes images of both the iris and the retina for biometric identification. Another multimodal ocular system captures and processes images of the iris and/or the from both eyes of a subject. Biometrics based on data provided by these systems are more accurate and robust than using biometrics that include data from only the iris or only the retina from a single eye. An exemplary embodiment emits photons to the iris and the retina of both eyes, an iris image sensor that captures an image of the iris when the iris reflects the emitted light, a retina image sensor that captures an image of the retina when the retina reflects the emitted light, and a controller that controls the iris and the retina illumination sources, where the captured image of the iris and the captured image of the retina contain biometric data. | 11-24-2011 |
| 20120200689 | LONG DISTANCE MULTIMODAL BIOMETRIC SYSTEM AND METHOD - A system for multimodal biometric identification has a first imaging system that detects one or more subjects in a first field of view, including a targeted subject having a first biometric characteristic and a second biometric characteristic; a second imaging system that captures a first image of the first biometric characteristic according to first photons, where the first biometric characteristic is positioned in a second field of view smaller than the first field of view, and the first image includes first data for biometric identification; a third imaging system that captures a second image of the second biometric characteristic according to second photons, where the second biometric characteristic is positioned in a third field of view which is smaller than the first and second fields of view, and the second image includes second data for biometric identification. At least one active illumination source emits the second photons. | 08-09-2012 |
| 20120215155 | CONTROLLED CROSS-LINKING INITIATION AND CORNEAL TOPOGRAPHY FEEDBACK SYSTEMS FOR DIRECTING CROSS-LINKING - Devices and approaches for activating cross-linking within corneal tissue to stabilize and strengthen the corneal tissue following an eye therapy treatment. A feedback system is provided to acquire measurements and pass feedback information to a controller. The feedback system may include an interferometer system, a corneal polarimetry system, or other configurations for monitoring cross-linking activity within the cornea. The controller is adapted to analyze the feedback information and adjust treatment to the eye based on the information. Aspects of the feedback system may also be used to monitor and diagnose features of the eye. Methods of activating cross-linking according to information provided by a feedback system in order to improve accuracy and safety of a cross-linking therapy are also provided. | 08-23-2012 |
| 20120310083 | SYSTEMS AND METHODS FOR MONITORING TIME BASED PHOTO ACTIVE AGENT DELIVERY OR PHOTO ACTIVE MARKER PRESENCE - Devices and approaches for monitoring time based photo active agent delivery or photo active marker presence in an eye. A monitoring system is provided for measuring the presence of a photo active marker by illuminating the eye so as to excite the photo-active marker and then observing characteristic emission from the photo active marker. Example systems incorporate Scheimpflug optical systems or slit lamp optical systems to observe cross sectional images of an eye to monitor instantaneous distribution, diffusion pattern, and rate of uptake of a photo active agent applied to an eye. Systems and methods further allow for utilizing the monitored distribution of photo active agent in the eye as feedback for a cross-linking system. | 12-06-2012 |
Michael Friedman, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120238549 | Nuclear Hormone Receptor Modulators - The invention provides a compound of Formula (I) | 09-20-2012 |
Michael Friedman, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090312338 | Novel Tricyclic Compounds - The invention provides a compound of Formula (I) | 12-17-2009 |
| 20110190489 | Novel Tricyclic Compounds - The invention provides a compound of Formula (Ia), (Ib), (Ic), (Id), (Ie), (If), (Ig), (Ih), (Ii), (Ij), (Ik), or (Il) as defined herein, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions. | 08-04-2011 |
| 20110311474 | Novel Tricyclic Compounds - The invention provides compounds of Formula (I) and Formula (II) | 12-22-2011 |
Nathaniel Dourif Friedman, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100191737 | SYSTEM AND METHOD OF SEARCHING FOR CLASSIFYING USER ACTIVITY PERFORMED ON A COMPUTER SYSTEM - The invention is directed to a system and method of managing information associated with user actions. A monitoring system may gather and store information associated with user actions. Relationships may be inferred between user actions based on time or other criteria. A user may define classifications of user actions. These classifications may be used to retrieve information associated with user actions. | 07-29-2010 |
Orrie Friedman, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090203644 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions - The present invention generally relates to the treatment and/or prevention of Alzheimer's disease, other neurodegenerative diseases, and/or diseases characterized by the presence of certain metal ions, by using certain compositions including silicon-amino compounds. In some cases, a silicon-amino compound of the invention may be bidentate, tridentate, or otherwise polydentate, and in certain instances, the silicon-amino compound, or a portion thereof, may sequester aluminum or other ions, for example, by electrostatically binding the ions. Further aspects of the invention relate to methods of making and using such compositions of the invention, as well as articles and kits associated with the compositions. | 08-13-2009 |
| 20100184724 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS - The present invention generally relates to the treatment and/or prevention of Alzheimer's disease, other neurodegenerative diseases, and/or diseases characterized by the presence of certain metal ions, by using certain compositions including organosilicon compounds. A composition of the invention may be administered to a mammal, such as a human. In some cases, the composition may include a silanol, a silandiol, a silantriol, or a cyclic organosilane, and/or be able to form a silanol, a silandiol, or a silantriol upon exposure to physiological conditions such as are found in the blood, in the stomach and/or gastrointestinal tract, or in the brain or other organ. In certain cases, the organosilicon compound may be bound to a moiety able to be transported across the blood-brain barrier into the brain, for example, an amino acid, a peptide, a protein, a virus, etc. The organosilicon compound may also be labeled (e.g., fluorescently or radioactively) in certain instances. In some embodiments, the composition, or a portion thereof, may sequester aluminum, copper, iron or other ions, for example, by electrostatically binding to the ions. The composition may also include other functionalities such as amines, certain alkyl and/or aryl moieties (including substituted alkyls and/or aryls), or hydrophobic moieties, for example, to facilitate transport of the organosilicon compound through the blood-brain barrier. | 07-22-2010 |
Richard E. Friedman, Springfield, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100274606 | COMPUTER SYSTEM AND METHOD FOR SUPPORTING AN E-COMMERCE ENTERPRISE HAVING ONLINE E-FRANCHISES - In one embodiment, a centralized website may be generated, stored, and executed on servers, where the centralized website has a particular “look and feel” (e.g., a template). In association with granting online e-franchise rights to a secondary entity, a secondary website may be generated, stored, and executed (e.g., on the servers) for the secondary entity and its particular field of endeavor, where each secondary website has the same particular look and feel as the centralized website. Stored content for the secondary website may be managed and monitored to ensure that it (in addition to the business practice of the secondary entity) is operated in accordance with standards set forth by the centralized entity. In this manner, novel e-commerce models may be created and operated, such as a virtual community of associated alliance members that may be accessed by outside users familiar with and confident in the community. | 10-28-2010 |
| 20110119153 | COMPUTER SYSTEM AND METHOD FOR GENERATING AND SUPPORTING FAIR TRADE RECEIPTS - In one embodiment, a novel “fair trade receipt” may be generated or otherwise supported for products and services found in commerce, such as in e-commerce or conventional in-person commerce. The fair trade receipt may be generated based upon supply-chain disclosures by sellers of the products/services related to fair trade principles. For instance, these disclosures may concern, among other things, the explicit or general nature of the material used, origin of the material, methods of collection, manufacturing methods and techniques, assembly of product parts, method and materials for packaging, shipping and transportation, consequences to the environment, etc. An algorithm used to compile the supply-chain disclosures may then result in a visual indication (e.g., a seal) and/or printed report (e.g., receipt) on the respective product or service criteria produced in advance of sale. | 05-19-2011 |
Rob Friedman, Waban, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20130012041 | ELECTRICAL AND MECHANICAL CONNECTOR ADAPTOR SYSTEM FOR MEDIA DEVICES - An electrical connector adaptor system for connecting a base media device having at least one integral electrical connector with one or more detachable second media devices. The integral connector is located within a mechanical adaptor for protecting a second media device from mechanical damage and/or to prevent lateral movement of the second media device. Each second media device has a connector that may differ from a connector of other second media devices, or the second media device may have a different form factor from other second media devices. The system includes a detachable electrical connector adaptor module which has a first electrical connector for mating with the base media device integral connector and a second electrical connector for mating with the second media device. | 01-10-2013 |
Robert U. Friedman, Westborough, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120284704 | PROCESSING, MODIFICATION, DISTRIBUTION OF INSTALLATION PACKAGES - According to example configurations, a customization engine receives a default installation package. The installation package supports installation of a respective application to a computing device. The customization engine further receives a set of rules indicating at least one alteration to be applied to the received installation package to transform the received installation package into a customized installation package. The customization engine further receives a set of data to be applied according to the rules. The customization engine modifies the received default installation package in accordance with the set of rules and supplied data to produce the customized installation package. | 11-08-2012 |