Friedemann
Friedemann Becker, Osterholz-Schambeck DE
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20080223197 | DEVICE AND METHOD FOR CONTROLLING PLAYBACK DEVICES FOR DIGITAL INFORMATION, ESPECIALLY MUSIC INFORMATION - The invention relates to a playback control unit which is connected with a playback device for CDs or records, wherein these provide coded information by means of which the playback device can be controlled. In this way, in addition to the playback speed, further functions can be controlled, namely selecting elements from a list, in particular a music archive, or determining skip marks or controlling software modules or the length of audio loops or a continuous modification of parameters, in particular audio effect parameters, for volume, filter, flange, echo, delay or a playback control of video sequences or parameters of video sequences, in particular color, resolution or parameters and positioning of objects in computer games. | 09-18-2008 |
20100011941 | Automatic Recognition and Matching of Tempo and Phase of Pieces of Music, and an Interactive Music Player - A method of matching the tempo and phase in pieces of music which allows the conjunction of the pieces of music to form a continuous stream of music. The interactive music player which digitally executes the method of matching the tempo and phase in pieces of music is also disclosed. | 01-21-2010 |
Friedemann Chmidt, Frankfurt Am Main DE
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20140357640 | N-[4-(1H-PYRAZOLO[3,4-B]PYRAZIN-6-YL)-PHENYL]-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS - The present invention relates to N-[4-(1H-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides of the formula (I), (R2)n wherein Ar, R1, R2 and n have the meanings indicated in the claims. The compounds of the formula (I) are valuable pharmacologically active compounds which modulate protein kinase activity, specifically the activity of serum and glucocorticoid regulated kinase (SGK), in particular of serum and glucocorticoid regulated kinase isoform 1 (SGK-1, SGK1), and are suitable for the treatment of diseases in which SGK activity is inappropriate, for example degenerative joint disorders or inflammatory processes such as osteoarthritis or rheumatism. The invention furthermore relates to processes for the preparation of the compounds of the formula (I), their use as pharmaceuticals, and pharmaceutical compositions comprising them. | 12-04-2014 |
Friedemann GÄdeke, Berlin DE
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20120056111 | SINGLE PHOTON EMISSION SYSTEM - An embodiment of the invention relates to a single photon emission system having a proximal end, a distal end, and a single photon emitter located between the proximal end and the distal end; wherein the single photon emission system is adapted to guide optical pump radiation, which is inputted at the proximal end to optically excite the single photon emitter, along a predefined direction that runs from the proximal end to the distal end; and wherein single photons emitted by said single photon emitter, are guided along said predefined direction to the distal end. | 03-08-2012 |
Friedemann Hoffmann, Gava (barcelona) ES
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20100061095 | LIGHTING DEVICE - Device including a tubular element ( | 03-11-2010 |
Friedemann Kendel, Stuttgart DE
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20130319303 | METHOD AND SYSTEM FOR MILLING A FUEL FOR AN OXY-FUEL COMBUSTION BURNER - The present disclosure relates to a method of milling a fuel for an oxy-fuel combustion burner, the method includes: separating air into a hot nitrogen gas stream, having a temperature of at least 150° C. and a purity of at least 98 mol-% nitrogen, and an oxygen gas stream; leading at least a part of the nitrogen gas stream to a fuel mill; milling the fuel by means of the fuel mill in a nitrogen rich atmosphere formed by means of the nitrogen gas stream; leading the at least a part of the nitrogen gas stream away from the milled fuel; leading the oxygen gas stream to the oxy-fuel combustion burner; conveying the milled fuel to the oxy-fuel combustion burner; and burning the fuel, by means of the oxy-fuel combustion burner, in an oxygen rich atmosphere formed by means of the oxygen gas stream. The present disclosure further relates to a system for milling a fuel for an oxy-fuel combustion burner as well as to a power plant comprising such a system. | 12-05-2013 |
Friedemann Krause, Penzberg DE
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20100159479 | TIMP-1 AS A MARKER FOR COLORECTAL CANCER - The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein TIMP-1 (tissue inhibitor of metalloproteinase 1) as a marker molecule in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a stool sample, derived from an individual, the method involving measuring TIMP-1 in the sample. Measurement of TIMP-1 can, e.g., be used in the early detection or diagnosis of colorectal cancer. | 06-24-2010 |
20130108626 | BLOOD PLASMA BIOMARKERS FOR BEVACIZUMAB COMBINATION THERAPIES FOR TREATMENT OF PANCREATIC CANCER | 05-02-2013 |
20130183301 | BLOOD PLASMA BIOMARKERS FOR BEVACIZUMAB COMBINATION THERAPIES FOR TREATMENT OF PANCREATIC CANCER - The present invention provides methods for improving the treatment effect of a chemotherapy regimen of a patient suffering from pancreatic cancer, in particular metastatic pancreatic cancer by adding bevacizumab (Avastin®) to a chemotherapy regimen by determining the expression level, in particular the blood plasma expression level, of one or more of VEGFA, VEGFR2 and PLGF relative to control levels of patients diagnosed with pancreatic cancer, in particular metastatic pancreatic cancer. In particular, the present invention provides methods of improving the treatment effect, wherein the treatment effect is the overall survival and/or progression-free survival of the patient. The present invention further provides for methods for assessing the sensitivity or responsiveness of a patient to bevacizumab (Avastin®) in combination with a chemotherapy regimen, by determining the expression level, in particular the blood plasma expression level, of one or more of VEGFA, VEGFR2 and PLGF relative to control levels in patients diagnosed with pancreatic cancer, in particular metastatic pancreatic cancer. | 07-18-2013 |
20130195857 | BLOOD PLASMA BIOMARKERS FOR BEVACIZUMAB COMBINATION THERAPIES FOR TREATMENT OF PANCREATIC CANCER - The present invention provides methods for improving the treatment effect of a chemotherapy regimen of a patient suffering from pancreatic cancer, in particular metastatic pancreatic cancer by adding bevacizumab (Avastin®) to a chemotherapy regimen by determining the expression level, in particular the blood plasma expression level, of one or more of VEGFA, VEGFR2 and PLGF relative to control levels of patients diagnosed with pancreatic cancer, in particular metastatic pancreatic cancer. In particular, the present invention provides methods of improving the treatment effect, wherein the treatment effect is the overall and/or progression-free survival of the patient. The present invention further provides methods for assessing the sensitivity or responsiveness of a pancreatic cancer patient to bevacizumab (Avastin®) in combination with a chemotherapy regimen, using similar methods. | 08-01-2013 |
20140302019 | BLOOD PLASMA BIOMARKERS FOR BEVACIZUMAB COMBINATION THERAPIES FOR TREATMENT OF PANCREATIC CANCER - The present invention provides methods for improving the treatment effect of a chemotherapy regimen of a patient suffering from pancreatic cancer, in particular metastatic pancreatic cancer by adding bevacizumab (Avastin®) to a chemotherapy regimen by determining the expression level, in particular the blood plasma expression level, of one or more of VEGFA, VEGFR2 and PLGF relative to control levels of patients diagnosed with pancreatic cancer, in particular metastatic pancreatic cancer. In particular, the present invention provides methods of improving the treatment effect, wherein the treatment effect is the overall survival and/or progression-free survival of the patient. The present invention further provides for methods for assessing the sensitivity or responsiveness of a patient to bevacizumab (Avastin®) in combination with a chemotherapy regimen, by determining the expression level, in particular the blood plasma expression level, of one or more of VEGFA, VEGFR2 and PLGF relative to control levels in patients diagnosed with pancreatic cancer, in particular metastatic pancreatic cancer. | 10-09-2014 |
Friedemann Lotsch US
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20150080769 | DEVICE FOR CRYOLIPOLYSIS - The invention relates to an applicator for use with a device for treating subcutaneous lipid-rich cells by cold treatment, wherein the applicator ( | 03-19-2015 |
Friedemann Lotsch, Dortmund DE
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20150080769 | DEVICE FOR CRYOLIPOLYSIS - The invention relates to an applicator for use with a device for treating subcutaneous lipid-rich cells by cold treatment, wherein the applicator ( | 03-19-2015 |
Friedemann Mehlhose, Freiberg DE
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20130292314 | SOOT WATER CLEANING BY MEANS OF CONTINUOUS PRESSURE FILTRATION - A pressure filtration system for cleaning residual quenching water of a gasifying device that gasifies carbon-containing fuels under elevated pressure is provided. The soot water from the quencher is passed to a filter system, which has pressure filter chambers operating alternately in filtering mode under gasifying pressure or in cleaning mode. The filtrate from these chambers is passed to a quenching water reservoir, from which the quencher is fed with quenching water. Only small temperature and pressure losses with respect to the residual quenching water leaving, and only a small additional amount of energy has to be expended to overcome the remaining pressure difference to bring the filtrate that is to be returned back to the gasifying pressure. The residual quenching water is cleaned substantially under gasifying pressure in a pressure filter, avoids flash evaporation of the residual quenching water into the vacuum area, with vapour cooling and a subsequent increase in pressure and reheating. | 11-07-2013 |
20140069525 | DEVICE FOR RELIABLE FILLING LEVEL CONTROL IN A QUENCHING CHAMBER THAT IS ARRANGED DOWNSTREAM OF ENTRAINED-FLOW GASIFICATION AND HAS INERT-GAS FLUSHING OF THE PRESSURE-RECORDING MEASURING LOCATION - A device for the reliable measurement and control of the filling level in the quencher sump of a quenching chamber arranged downstream of the gasifying chamber is provided. The device has a differential-pressure transmitter. The measuring location recording the pressure of the gas chamber is flushed with inert gas. The device unproblematically senses the pressures in the quenching chamber and at the bottom of the quencher sump. The difference between which is used as a controlled variable for the filling level. | 03-13-2014 |
Friedemann Nordt, Eutingen DE
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20130199631 | Pressure/Flow Regulator - A pressure/flow regulator includes a pressure control valve, a flow control valve, and a first control connection configured to set a variable displacement pump. The control connection is configured to be discharged to a tank by the flow control valve via a control edge of the pressure control valve that is open in the idle position of a valve piston of the pressure control valve. | 08-08-2013 |
20140103233 | HYDRAULIC VALVE ARRANGEMENT AND HYDRAULIC MACHINE ARRANGEMENT HAVING A VALVE ARRANGEMENT OF THIS KIND - A hydraulic valve arrangement, in particular a control valve arrangement, of a hydraulic machine, in particular a hydraulic pump, includes at least one valve with a valve body penetrated by a pressure medium passage. The pressure medium passage has a minimum cross section that gives rise, in normal operation, to a control pressure downstream of the minimum cross section in accordance with a pressure acting at a pressure port of the valve. The minimum cross section is arranged close to a pressure medium passage mouth which is arranged upstream or is configured to be subjected to the high pressure. A hydraulic machine arrangement, in particular a pump arrangement, includes the hydraulic valve arrangement. | 04-17-2014 |
20140109989 | HYDRAULIC VALVE ARRANGEMENT - A hydraulic valve arrangement, in particular a control valve arrangement of an axial piston machine, includes at least two valves that have springs supported in each case on a spring seat. The two spring seats are connected to one another with a material-to-material fit in one or more of a non-positive manner and a positively locking manner. | 04-24-2014 |
20150068394 | Hydrostatic Variable Displacement Axial Piston Machine, in particular Hydrostatic Variable Displacement Axial Piston Motor - A hydrostatic axial piston machine includes a swashplate with an oblique surface formed thereon. Working pistons, which revolve and are supported by the oblique surface, are axially positioned on the swashplate with respect to a drive shaft. An adjusting cylinder, coupled to the swashplate, is configured to produce a pivoting moment and pivot the swashplate about a pivoting axis. Displacement of the working cylinders per revolution around the drive shaft is adjustable by adjusting a pivoting angle of the oblique surface. The adjustment of the pivoting angle is configured to pass beyond zero degrees, such that the direction of rotation of the drive shaft is changeable. The pivoting axis is at a distance from an axis of rotation of the drive shaft, such that an internal counter pivoting moment counteracting the pivoting moment is produced during operation of the axial piston machine when the working pistons are subjected to pressure. | 03-12-2015 |
Friedemann Paul, Berlin DE
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20150157202 | Method and System for Optic Nerve Head Shape Quantification - A fully automated optic nerve head description system based on optical coherence tomography that works with heavily deformed nerve heads and allows the generation of parameters describing swelling, including correlation with intracranial pressure both in detection and progression. | 06-11-2015 |
Friedemann Pieschel, Bad Soden DE
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20100083567 | Liquid Fuels as Diesel Engine Fuel Mixture or Light Heating Oil - Liquid fuels such as a diesel engine fuel mixture or a light heating oil have as a main component, a fossil diesel engine fuel and/or a biodiesel and/or a vegetable oil and additives. The object is to provide an alternative mixture component for diesel engine fuels or light heating oil which is suitable not only for fossil diesel engine fuels but also biodiesel or vegetable oil, which may be produced inexpensively and which meets the requirements as a pure bio propellant. It is proposed that diesel engine fuel mixture or light heating oil contains, as a mixture component, diethyl oxalate. The heating oil can be made of a mixture which originates from the refining of crude oil and is admixed with up to 25% by volume diethyl oxalate. In addition, for the heating oil, use can be made of a mixture which consists of vegetable oils and up to 50% by volume diethyl oxalate. | 04-08-2010 |
Friedemann Rex, Marl DE
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20100024614 | METHOD FOR CUTTING OR PUNCHING CERAMIC-CONTAINING COMPOSITE MATERIALS - A method for cutting and/or punching material in which abrasive particles are present within and/or on the surface of a substrate is provided. The material cut or punched is useful as a ceramic separator for electrochemical applications including capacitors, supercapacitors, batteries, lithium ion batteries and lithium metal batteries. | 02-04-2010 |
Friedemann Schmidt, Frankfurt Am Main DE
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20130072493 | N-[4-(1H-PYRAZOLO[3,4-b]PYRAZIN-6-YL)-PHENYL]-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS - The present invention relates to N-[4-(1H-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides of the formula I, | 03-21-2013 |
20140288083 | N-[4-(1H-PYRAZOLO[3,4-B]PYRAZIN-6-YL)-PHENYL]-SULFONAMIDES AND THEIR USE AS PHARMACEUTICALS - The present invention relates to N-[4-(1H-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides of the formula I, | 09-25-2014 |
Friedemann Schmidt, Asperg DE
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20130264881 | DIFFERENTIAL INTERFACE FOR INTER-DEVICE COMMUNICATION IN A BATTERY MANAGEMENT AND PROTECTION SYSTEM - A multi-cell battery stack includes a microcontroller and a string of battery management and protection IC devices connected to one another in a daisy chain configuration. Each battery management and protection IC device can include a communication interface circuit includes pairs of differential input signal lines, receivers including respective current comparator circuits to receive differential signals on the differential input signal lines, and transmitters to provide outgoing differential signals on the differential input signal lines. A digital circuit block allows signals to pass between the receivers and transmitters. | 10-10-2013 |
Friedemann Scholz, Berlin DE
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20090180499 | FREQUENCY CHANGING DEVICE - The invention relates to a frequency changing device comprising a laser having a waveguide and a nonlinear optical medium which changes the frequency of the light generated by the laser. It is provided that the waveguide of the laser at least adjacent to the exit facet of the laser runs at an angle with respect to the perpendicular to the exit facet, that the exit facet of the laser and the entrance facet of the nonlinear optical medium are arranged parallel to one another, and that the exit facet of the laser and the entrance facet of the nonlinear optical medium are oriented with respect to one another in such a way that the condition of Snell's law is met, i.e., | 07-16-2009 |
Friedemann Schwenkreis, Leinfelden-Echterdingen DE
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20120297362 | EDITING SOURCE CODE - A method for editing source code includes receiving a modification to the source code made by a user, determining whether the modification would change the semantics of the source code, and handling the modification depending on the result of the determining. | 11-22-2012 |
Friedemann Taut, Konstanz DE
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20090011978 | Use of Surfactant Preparations for the Treatment of Surgical Adhesions - The invention describes the use of surfactant comprising phospholipids and pulmonary surfactant proteins for the treatment of surgical adhesions. | 01-08-2009 |
20130142782 | HUMIDIFIED PARTICLES COMPRISING A THERAPEUTICALLY ACTIVE SUBSTANCE - The invention relates to aerosolized and humidified particles comprising a therapeutically active substance which can be obtained by suspending dry inhalable particles in a carrier gas, adding water vapor and causing condensation of water on the particles. The invention further relates to methods to generate these particles, and apparatus useful to carry out such methods. | 06-06-2013 |
20130152925 | DEVICE AND SYSTEM FOR DELIVERY OF AN AEROSOL TO A PATIENT ON VENTILATORY SUPPORT - A device and system for delivering an aerosol to a patient on ventilatory support comprise a contact component | 06-20-2013 |
Friedemann Weber, Freiburg DE
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20110110976 | RIFT VALLEY FEVER VIRUS-LIKE PARTICLES AND THEIR USE FOR IMMUNIZATION AND AS TEST SYSTEM - Disclosed is a method for producing virus-like particles (VLP) that comprises the steps of (a) transfecting a mammalian cell line with several independent vectors, including (1) a vector containing at least a substantial part of the M gene from Rift Valley Fever Virus, (2) a vector containing at least a substantial part of the L gene from Rift Valley Fever Virus, (3) a vector containing at least a substantial part of the N gene from Rift Valley Fever Virus and (4) a vector containing a multicloning site flanked by the non-coding 5′- and 3′-ends of the L-, M- or S-segment of Rift Valley Fever Virus, and (b) culturing the transfected mammalian cell line under suitable conditions and obtaining the VLPs from the supernatant of the transfected cultured cell lines. The so-obtained VLPs can be used for vaccination and in methods for testing the antiviral activity of compounds. | 05-12-2011 |
Friedemann Weber, Erbstetten DE
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20140234075 | EXHAUST GAS TURBOCHARGER - An exhaust gas turbocharger may include a shaft mounted in a bearing housing carrying a compressor wheel and a turbine wheel. The shaft may include a sealing bush arranged on the shaft in a rotationally fixed manner. The sealing bush together with a bearing housing cover may at least partially delimit an annular oil centrifuging space arranged coaxially to the sealing bush. The bearing housing cover may include a guiding nib located radially outside the sealing bush partially covering the sealing bush in axial direction. The guiding nib may be configured to guide oil separated in the oil centrifuging space onto the rotating sealing bush. The rotating sealing bush may be configured to direct the oil into the oil centrifuging space in response to centrifugal force creating an oil swirl. | 08-21-2014 |
Friedemann Wolpers, Urbach DE
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20140095050 | Hybrid Drive Train, Hybrid Vehicle, and Operating Method - A method for operating a hybrid drive train involves operating an internal combustion engine using a low-NOx operating method in a range of low and average rotational speeds and/or loads, and operating the internal combustion engine using a spark ignition operating method in a range of higher rotational speeds and/or loads. | 04-03-2014 |