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Frickel

Eva-Maria Frickel, London GB

Patent application numberDescriptionPublished
20110302665NON-HUMAN MAMMALS WITH T OR B CELLS HAVING PREDEFINED SPECIFICITY - The present invention provides non-human mammals, e.g., mice, generated from a T cell or B cell with a predefined specificity or isolated from an organism suffering from a condition of interest. In some embodiments the non-human mammals are not genetically modified. Also provided are methods of using the non-human animals.12-08-2011

Fritz-Frieder Frickel, Deidesheim DE

Patent application numberDescriptionPublished
20100009961DIPEPTIDYL PEPTIDASE-IV INHIBITORS - The present invention relates generally to pyrrolidine and thiazolidine DPP-IV inhibitor compounds. The present invention also provides synthetic methods for preparation of such compounds, methods of inhibiting DPP-IV using such compounds and pharmaceutical formulations containing them for treatment of DPP-IV mediated diseases, in particular, Type-2 diabetes.01-14-2010

Fritz-Frieder Frickel, Deidensheim DE

Patent application numberDescriptionPublished
20110112051Dipeptidyl Peptidase-IV Inhibitors - The present invention relates generally to pyrrolidine and thiazolidine DPP-IV inhibitor compounds. The present invention also provides synthetic methods for preparation of such compounds, methods of inhibiting DPP-IV using such compounds and pharmaceutical formulations containing them for treatment of DPP-IV mediated diseases, in particular, Type-2 diabetes.05-12-2011

Henry Frickel, Bel Air, MD US

Patent application numberDescriptionPublished
20090031866Cam Compression Tool - A variable compression tool comprising a retaining surface attached to a lever arm and a cam surface attached to a second lever arm. The two arms are moveably connected through a fixed pivot point. The profile of the jaw pocket may be of various shapes. In one instantiation, the jaw pocket conforms to at least two sides of a nut. The orientation of the cam surface to the jaw pocket is such that the force generated by closing the jaws forces the nut into the retaining surface. Adjustment of the cam lever arm is regulated by an eccentric cam adjuster bearing which changes the effective center of rotation of lever arm two in two dimensions simultaneously by rotation of the bearing.02-05-2009