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Frenzel

Brian D. Frenzel, Los Altos, CA US

Patent application numberDescriptionPublished
20090325893DOXORUBICIN ADJUVANTS TO REDUCE TOXICITY AND METHODS FOR USING THE SAME - Methods are provided for using doxorubicin active agents in which reduced host toxicity is observed. Aspects of the methods including administering to a subject an effective amount of a doxorubicin active agent in conjunction with a doxorubicin toxicity-reducing adjuvant, e.g., a nitrone compound, or a nitrone compound in combination with a bisdioxopiperazine compound. Also provided are compositions for use in practicing the subject methods. The methods and compositions find use in a variety of different applications, including in the treatment of a variety of different disease conditions.12-31-2009
20090325969METHOTREXATE ADJUVANTS TO REDUCE TOXICITY AND METHODS FOR USING THE SAME - Methods are provided for using methotrexate (MTX) active agents in which reduced host toxicity is observed. Aspects of the methods include administering to a subject an effective amount of an MTX active agent in conjunction with a MTX toxicity-reducing adjuvant, such as a 2,2′-anhydropyrimidine, a derivative thereof or a uridine phosphorylase inhibitor. Also provided are compositions and kits that find use in practicing embodiments of the invention. The methods and compositions find use in a variety of applications, including the treatment of a variety of different disease conditions.12-31-2009

Gary Frenzel, Mountain View, CA US

Patent application numberDescriptionPublished
20090088336MODULAR POINT-OF-CARE DEVICES, SYSTEMS, AND USES THEREOF - The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.04-02-2009

Hoyt Frenzel, Arlington, TX US

Patent application numberDescriptionPublished
20100217195Needle for Bloodless IV - An intravenous catheter system having a retractable needle system and a body system is disclosed. The retractable needle system includes a housing, a needle, a docking feature, and an optional anti-shearing mechanism. The body system includes a body, at least one hub, a catheter connector, at least one plug, a plug recoil mechanism, a locking mechanism, a flash chamber, and a flash window.08-26-2010

Mark P. Frenzel, Sugar Land, TX US

Patent application numberDescriptionPublished
20080262810NEURAL NET FOR USE IN DRILLING SIMULATION - A method of optimizing a drilling tool assembly including inputting well data into an optimization system, the optimization system having an experience data set and an artificial neural network. The method further including comparing the well data to the experience data set and developing an initial drilling tool assembly based on the comparing the well data to the experience data, wherein the drilling tool assembly is developed using the artificial neural network. Additionally, the method including simulating the initial drilling tool assembly in the optimization system and creating result data in the optimization system based on the simulating.10-23-2008

Robert Anthony Frenzel, Waller, TX US

Patent application numberDescriptionPublished
20100229962Multi-component Metal Seat Design for Ball Valves - A floating ball valve has a metal multiple component seat installed in the seat pocket. The multiple component seat further includes a support ring and at least one seal element. The support ring and the seal element are juxtaposed and both are adjacent to the ball when the floating ball valve is in a closed position. The support ring is in a overlapping complimentary position with respect to the seal element, the seal element having greater elasticity than the support ring and the support ring having a greater load bearing strength than the seal element.09-16-2010