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Frederick R. Blattner, Madison US

Frederick R. Blattner, Madison, WI US

Patent application numberDescriptionPublished
20090053766METHODS AND COMPOSITIONS FOR PRODUCING RECOMBINANT PROTEINS USING A GENE FOR TRNA - The invention relates to host cells with improved protein expressed properties. The host cells comprise rare tRNA genes within the one or more rRNA operons.02-26-2009
20090053792OXYGEN-REGULATED MICROORGANISMS - The present invention relates to novel strains of microorganisms with oxygen-regulated metabolism. The microorganisms have higher growth rates and are more efficient than parental strains. The microorganisms may be used to produce a variety of products of interests, such as recombinant proteins, nucleic acids, such as DNA, amino acids, and chemicals.02-26-2009
20090068707PLASMID DNA PREPARATIONS AND METHODS FOR PRODUCING SAME - The various embodiments of the present invention relate generally to plasmid DNA preparations and to methods for producing and using such preparations.03-12-2009
20090075333Reduced Genome E. Coli - Reduced genome strains of 03-19-2009
20100144548VECTOR SYSTEMS - The present invention relates generally to the field of molecular biology and genomics. More specifically, the present invention concerns the cloning of nucleic acid molecules and the production of nucleic acid libraries, as well as the expression of recombinant proteins and bactofection.06-10-2010
20100227780Methods for the synthesis of arrays of DNA probes - The synthesis of arrays of DNA probes sequences, polypeptides, and the like is carried out using a patterning process on an active surface of a substrate. An image is projected onto the active surface of the substrate utilizing reflective projection optics. The projection optics project a light image onto the active surface of the substrate to deprotect linker molecules thereon. A first level of bases may then be applied to the substrate, followed by development steps, and subsequent exposure of the substrate utilizing a different light image, with further repeats until the elements of a two dimensional array on the substrate surface have an appropriate base bound thereto.09-09-2010
20100330623COMPOSITIONS AND METHODS FOR AMINO ACID BIOSYNTHESIS - The present invention relates generally to compositions and methods useful for, inter alia, production of commercial biologic products such as amino acids. More specifically, the present invention relates to genetically modified strains of microorganisms and the use thereof for the production of commercial products. The present invention also provides, inter alia, novel isolated DNA, nucleic acid, vectors and reduced genome bacteria.12-30-2010
20110165680CLEAN GENOME BACTOFECTION - Methods for introducing and expressing genes in animal cells are provided comprising infecting the animal cells with live invasive reduced-genome bacteria comprising a eukaryotic expression cassette comprising said gene. Also provided are methods for producing a pluripotent stem (iPS) cell from a mammalian somatic cell comprising infecting the somatic cell with live invasive reduced-genome bacteria comprising one or more eukaryotic expression cassettes comprising at least a gene encoding the transcription factor Oct3/4 and a gene encoding a member of the SRY-related HMG-box (Sox) transcription factor family.07-07-2011

Patent applications by Frederick R. Blattner, Madison, WI US