Patent application number | Description | Published |
20090036451 | Chemical inducers of neurogenesis - The present invention relates to compounds and methods for inducing neuronal differentiation in normal neural stem cells and brain cancer stem cells. The methods may take place in vitro, such as in isolates from the adult mammalian brain, or in vivo. Compounds and methods described herein may find use in the treatment of neurodegenerative and psychiatric diseases, the repair and regeneration of the nervous system, and in treatment of neurologic malignancy. | 02-05-2009 |
20090076103 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR - The present invention relates to screens for compounds that can induce stem cell differentiation. In addition, isoxazoles and sulfonyl hydrazones are identified as general classes of compounds that can induce differentiation of stem cells into cells of neuronal and cardiac fate, respectively. | 03-19-2009 |
20130143885 | CHEMICAL INDUCERS OF NEUROGENESIS - The present invention relates to compounds and methods for inducing neuronal differentiation in normal neural stem cells and brain cancer stem cells. The methods may take place in vitro, such as in isolates from the adult mammalian brain, or in vivo. Compounds and methods described herein may find use in the treatment of neurodegenerative and psychiatric diseases, the repair and regeneration of the nervous system, and in treatment of neurologic malignancy. | 06-06-2013 |
20140364467 | CHEMICAL INDUCERS OF NEUROGENESIS - The present invention relates to compounds and methods for inducing neuronal differentiation in normal neural stem cells and brain cancer stem cells. The methods may take place in vitro, such as in isolates from the adult mammalian brain, or in vivo. Compounds and methods described herein may find use in the treatment of neurodegenerative and psychiatric diseases, the repair and regeneration of the nervous system, and in treatment of neurologic malignancy. | 12-11-2014 |
Patent application number | Description | Published |
20110303412 | OIL-BASED GROUTING COMPOSITION WITH AN INSULATING MATERIAL - According to an embodiment, a method for thermally insulating a portion of a tubular located inside an enclosed conduit comprises the steps of: (A) introducing a grouting composition into an annulus between the tubular and the enclosed conduit, the grouting composition comprising: (i) an oil-swellable binding material; and (ii) a hydrocarbon liquid, wherein the hydrocarbon liquid is the continuous phase of the grouting composition; and (iii) an insulating material comprising a hollow microsphere; and (B) allowing or causing the grouting composition to set after the step of introducing, wherein after setting the grouting composition has a thermal conductivity of less than 0.3 BTU/hr·ft·° F. According to another embodiment, a grouting composition for use in insulating a portion of a tubular located inside an enclosed conduit comprises: (A) an oil-swellable binding material comprising a organophilic clay; and (B) a hydrocarbon liquid, wherein the hydrocarbon liquid is the continuous phase of the grouting composition; and (C) an insulating material comprising a hollow microsphere, wherein after the grouting composition has set, the grouting composition has a thermal conductivity of less than 0.3 BTU/hr·ft·° F. | 12-15-2011 |
20110305830 | WATER-BASED GROUTING COMPOSITION WITH AN INSULATING MATERIAL - According to an embodiment, a method for thermally insulating a portion of a tubular located inside an enclosed conduit comprises the steps of: (A) introducing a grouting composition into an annulus between the tubular and the enclosed conduit, the grouting composition comprising: (i) a water-swellable binding material comprising water-swellable clay; (ii) an aqueous liquid, wherein the aqueous liquid is the continuous phase of the grouting composition; and (iii) an insulating material; and (B) allowing the grouting composition to set after the step of introducing, wherein after setting the grouting composition has a thermal conductivity of less than 0.3 BTU/hr·ft·° F. According to another embodiment, a grouting composition for use in insulating a portion of a tubular located inside an enclosed conduit comprises: (A) a water-swellable binding material comprising water-swellable clay; (B) an aqueous liquid, wherein the aqueous liquid is the continuous phase of the grouting composition; and (C) an insulating material, wherein after the grouting composition has set, the grouting composition has a thermal conductivity of less than 0.3 BTU/hr·ft·° F. | 12-15-2011 |
20120260826 | OIL-BASED GROUTING COMPOSITION WITH AN INSULATING MATERIAL - A grouting composition for use in insulating a portion of a tubular located inside an enclosed conduit comprises: (A) an oil-swellable binding material comprising a organophilic clay; and (B) a hydrocarbon liquid, wherein the hydrocarbon liquid is the continuous phase of the grouting composition; and (C) an insulating material comprising a hollow microsphere, wherein after the grouting composition has set, the grouting composition has a thermal conductivity of less than 0.3 BTU/hr·ft·° F. | 10-18-2012 |
20140291028 | Methods of Beneficiating Drilling Fluids Comprising Low- and High-Quality Clays - Beneficiating drilling fluids that comprise low-quality clay and high-quality clay may be performed by adding a polymer and a high-quality clay to a fluid that comprises an aqueous base fluid and a low-quality clay, so as to yield a drilling fluid, wherein the ratio of the low-quality clay to the high-quality clay is about 90:10 to about 80:20. | 10-02-2014 |
20140291029 | Beneficiated Clay Viscosifying Additives - Beneficiated clay viscosifying additives may include a low-quality clay and a polymer coated high-quality clay that comprises a high-quality clay at least partially coated with a polymer, wherein the ratio of low-quality clay to high-quality clay is about 90:10 to about 80:20 by weight. Such beneficiated clay viscosifying additives may be used in drilling fluids. | 10-02-2014 |
20140321914 | Controlled Dewatering of Confined, Saturated Formations in Excavation Mines - Methods to control dewatering of confined, saturated formations in excavation mines may include treating a portion of an untreated smectite shale barrier with a dewatering fluid thereby yielding a treated smectite shale barrier, wherein the untreated smectite shale barrier is associated with a confined, saturated formation that comprises water, and wherein the dewatering fluid comprises an aqueous base fluid and a dewatering additive; and draining at least a portion of the water from the confined, saturated formation through the treated smectite shale barrier. In some instances, the dewatering additive may include potassium citrate and potassium nitrate each independently in a concentration of about 0.5% to about 5% by weight of the aqueous base fluid. | 10-30-2014 |
20140321925 | Methods for Strengthening Smectite Shale in Highwall Mines - Stabilizing smectite shale may include treating a smectite shale in a subsurface formation with a dewatering fluid so as to yield a stabilized smectite shale, the dewatering fluid comprising an aqueous base fluid and a dewatering additive. In some instances, at least a portion of a highwall in a highwall mine may be formed at a highwall mine site comprising stabilized smectite shale. | 10-30-2014 |
20150232384 | WATER-BASED GROUTING COMPOSITION WITH AN INSULATING MATERIAL - According to an embodiment, a method for thermally insulating a portion of a tubular located inside an enclosed conduit comprises the steps of: (A) introducing a grouting composition into an annulus between the tubular and the enclosed conduit, the grouting composition comprising: (i) a water-swellable binding material comprising water-swellable clay; (ii) an aqueous liquid, wherein the aqueous liquid is the continuous phase of the grouting composition; and (iii) an insulating material; and (B) allowing the grouting composition to set after the step of introducing, wherein after setting the grouting composition has a thermal conductivity of less than 0.3 BTU/hr·ft·° F. According to another embodiment, a grouting composition for use in insulating a portion of a tubular located inside an enclosed conduit comprises: (A) a water-swellable binding material comprising water-swellable clay; (B) an aqueous liquid, wherein the aqueous liquid is the continuous phase of the grouting composition; and (C) an insulating material, wherein after the grouting composition has set, the grouting composition has a thermal conductivity of less than 0.3 BTU/hr·ft·° F. | 08-20-2015 |
Patent application number | Description | Published |
20110003262 | Dental Appliance - Disclosed is a mandibular positioning apparatus that uses elastic bands to pull the lower jaw forward including a set of plastic retention hooks, one on the right and one on the left of an upper plastic base, and a lower plastic base conforming to lower teeth with a vertical displacement on the base. | 01-06-2011 |
20120295211 | Method and Apparatus for Vacuum-Formed Dental Appliance - An appliance and methods are described that include embodiments of a mandibular advancement or positioning device which can use elastic bands to pull the jaw forward. The appliance has an upper plastic tray conforming to the patient's upper teeth and including a set of retention hooks coupled to the upper plastic tray via being encased in plastic, one on the right and one on the left anterior buccal portion of an upper plastic base. The appliance also has a lower plastic tray conforming to the patient's lower teeth and has a set of bite pads integrated with a second set of plastic retention hooks encased in plastic extending outwardly from the tooth. The appliance includes the upper and lower plastic trays and specially formed elastic bands of a plurality of lengths and strengths replaceably attached to the retention hooks on both sides of the trays to pull the mandible forward for treatment. | 11-22-2012 |
20150059766 | Method and Apparatus for Vacuum-Formed Dental Appliance - An appliance and methods are described that include embodiments of a mandibular advancement or positioning device which can use elastic bands to pull the jaw forward. The appliance has an upper plastic tray conforming to the patient's upper teeth and including a set of retention hooks coupled to the upper plastic tray via being encased in plastic, one on the right and one on the left anterior buccal portion of an upper plastic base. The appliance also has a lower plastic tray conforming to the patient's lower teeth and has a set of bite pads integrated with a second set of plastic retention hooks encased in plastic extending outwardly from the teeth. The appliance includes the upper and lower plastic trays and specially formed elastic bands of a plurality of lengths and strengths replaceably attached to the retention hooks on both sides of the trays to pull the mandible forward for treatment. | 03-05-2015 |
20160106572 | Method and Apparatus for Vacuum-Formed Dental Appliance - An appliance and methods are described that include embodiments of a mandibular advancement or positioning device which can use elastic bands to pull the jaw forward. The appliance has an upper plastic tray conforming to the patient's upper teeth and including 3D printed sets of retention hooks coupled to the upper plastic tray via being encased in plastic, one on the right and one on the left anterior buccal portion of an upper plastic base. The appliance also has a lower plastic tray conforming to the patient's lower teeth including mandibular dentition, and includes having a 3D printed bite pad which opens the bite vertically. The lower tray also has a set of 3D printed plastic retention hooks encased in plastic extending outwardly from the teeth, one on the right and one on the left of the posterior buccal portion of the lower plastic base. Elastic bands of different lengths and strengths are attached to both the top and bottom retention hooks on both sides of the trays to pull the mandible forward for treatment. | 04-21-2016 |