Patent application number | Description | Published |
20100167990 | Pharmaceutical Formulations Comprising an Insulin Derivative - The invention concerns a soluble pharmaceutical formulation comprising an insulin derivative wherein the formulation further comprises more than 4 zinc atoms per 6 molecules of the insulin derivative, and a citric acid monohydrate and/or a histidine compound used in an amount sufficient to increase the tendency of the insulin derivative to self-associate into dodecamers. The invention further comprises a process for preparing the soluble pharmaceutical formulation. | 07-01-2010 |
20110092419 | PROTEASE-STABILIZED INSULIN ANALOGUES - The present invention relates to novel insulin analogues comprising mutations at position A14 in the A chain and at positions B27, B28, B29 and B30 in the B chain and exhibiting resistance towards protease; a method for the preparation of such insulin analogues; insulin preparations containing the insulin analogues of the invention; and, a method of treating diabetes mellitus using these insulin analogues. | 04-21-2011 |
20130059781 | Long-Acting Gastrin Derivatives - The present invention relates to gastrin derivatives comprising gastrin or an analogue or fragment thereof and a derivatisation group and therapeutic use thereof. | 03-07-2013 |
20130157938 | Insulin Derivatives Containing Additional Disulfide Bonds - The present invention is related to insulin derivatives containing additional disulfide bonds and methods of making such. | 06-20-2013 |
20130172247 | Insulin Analogues Containing Additional Disulfide Bonds - The present invention is related to insulin analogues containing additional disulfide bonds and methods of making such. | 07-04-2013 |
20130178414 | Human Insulin Containing Additional Disulfide Bonds - The present invention is related to human insulin containing additional disulfide bonds and methods of making such. | 07-11-2013 |
20140031279 | Human Insulin Analogues and Derivatives Comprising Cysteine Substitutions - The present invention relates to human insulin analogues containing a substituting cysteine, to human insulin derivatives containing a PEGylated substituting cysteine and methods of making such. The compounds of the invention may be useful for the treatment of diabetes. | 01-30-2014 |
20140371140 | Insulin derivatives Containing Additional Disulfide bonds - The present invention is related to insulin derivatives containing additional disulfide bonds and methods of making such. | 12-18-2014 |
20150038435 | N-TERMINALLY MODIFIED OLIGOPEPTIDES AND USES THEREOF - The present invention is related to N-terminally fatty acid modified peptides or oligopeptides and pharmaceutical compositions comprising such. | 02-05-2015 |