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| 20100104611 | ANTIPERSPIRANT COMPOSITIONS - Anhydrous antiperspirant compositions comprising particulate antiperspirant active; capsules comprising a shear-sensitive shell which encapsulates perfume; and a carrier for the particulate antiperspirant active and capsules; wherein the capsules have a shell of cross-linked gelatin coacervate having a thickness of from 0.25 to 9 μm and providing from 10 to 40% by weight of the capsules, a volume average particle diameter of from 25 to 70 μm, a ratio of shell thickness to the average particle diameter in the range of from 1:5 to 1:120, and a Hysitron hardness in the range of from 1.5 MPa to 50 MPa. | 04-29-2010 |
| 20100104612 | ANTIPERSPIRANT COMPOSITIONS - Fragrance leaches rapidly from capsules having shells made from cross linked gelatin into volatile silicone oils. Unfortunately such oils are much favoured for anhydrous antiperspirant compositions. The rate and extent of leaching can be ameliorated greatly or nearly halted by employing as carrier oil, an ester oil or an ether oil, even in the presence of a significant fraction of volatile silicone oil. Consequently, the capability of antiperspirant compositions to generate detectable fragrance over an extended period after application to the skin is improved by employing ester or ether oil as all or part of the carrier liquid in which the antiperspirant is suspended. | 04-29-2010 |
| 20100104613 | ANTIPERSPIRANT OR DEODORANT COMPOSITIONS - It is desirable for antiperspirant or deodorant roll-on compositions to be able to deliver fragrance over an extended period of time after application, but previously contemplated encapsulates were based on starch or similar water-soluble or dispersible shell materials, rendering them ineffective in aqueous emulsions. | 04-29-2010 |
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| 20100209483 | TRANSDERMAL DELIVERY OF MEPTAZINOL - A delivery system for the delivery of a salt of meptazinol which increases the bioavailability of meptanizol by an effective amount to provide analgesic relief is disclosed. One embodiment of the delivery system is a transdermal device which increases the skin flux of meptazinol by an effective amount to provide analgesic relief. Also disclosed are methods of providing analgesic relief. | 08-19-2010 |
| 20100286186 | NOVEL DICARBOXYLIC ACID LINKED AMINO ACID AND PEPTIDE PRODRUGS OF OPIOIDS AND USES THEREOF - The present invention concerns dicarboxylic acid linked amino acid and peptide prodrugs of opioid analgesics and pharmaceutical compositions containing such prodrugs. Methods for providing pain relief, decreasing the adverse GI side effects of the opioid analgesic and increasing the bioavailability of the opioid analgesic with the aforementioned prodrugs are also provided. In one embodiment, prodrugs having the amino acid side chains of valine, leucine, isoleucine and glycine; and mono-, di- and tripeptides thereof are provided. | 11-11-2010 |
| 20110015182 | NOVEL CARBAMATE AMINO ACID AND PEPTIDE PRODRUGS OF OPIOIDS AND USES THEREOF - Carbamate linked prodrugs of meptazinol and other opioid analgesics are provided. The prodrug moiety may comprise a single amino acid or short peptide. Additionally, the present invention relates to methods for reducing gastrointestinal side effects in a subject, the gastrointestinal side effects being associated with the administration of an opioid analgesic. The methods comprise orally administering an opioid prodrug or pharmaceutically acceptable salt thereof to a subject, wherein the opioid prodrug is comprised of an opioid analgesic covalently bonded through a carbamate linkage to a prodrug moiety, and wherein upon oral administration, the prodrug or pharmaceutically acceptable salt minimizes at least one gastrointestinal side effect associated with oral administration of the opioid analgesic alone. Compositions for use with the method are also provided. | 01-20-2011 |
| 20110098278 | GALANTAMINE AMINO ACID AND PEPTIDE PRODRUGS AND USES THEREOF - Prodrugs of galantamine or its 3-hydroxy metabolite with amino acids or short peptides, pharmaceutical compositions containing such prodrugs and methods for treating a memory or cognition disorder with the galantamine prodrugs are provided herein. Prodrugs having side chains of valine, phenylalanine, tyrosine or para amino benzoic acid and mono-, di- and tripeptides thereof are preferred. Additionally, methods for avoiding or minimizing the adverse gastrointestinal side effects associated with galantamine administration, as well as improving the pharmacokinetics of galantamine are provided herein. | 04-28-2011 |
| 20110190267 | PRODRUGS OF OPIOIDS AND USES THEREOF - The present invention concerns prodrugs of opioid analgesics and pharmaceutical compositions containing such prodrugs. Methods for providing more consistent pain relief by increasing the bioavailability of the opioid analgesic with the aforementioned prodrugs are provided. The invention also provides for decreasing the adverse GI side effects of opioid analgesics. | 08-04-2011 |
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| 20090028085 | Method for providing measurement gaps - A method comprising interrupting the reception of a first transmission to receive a predetermined channel; determining from receipt of said predetermined channel first timing information associated with a second channel; and interrupting the reception of said first transmission at a time defined by said first timing information to receive said second channel. | 01-29-2009 |
| 20100220862 | Method, Apparatus And Computer Program Product For Providing Security During Handover Between A Packet-Switched Network And A Circuit-Switched Network - A method, apparatus and computer program product are provided to facilitate security in response to a handover from an initial network to a subsequent network, such as a handover between a packet-switched network and a circuit-switched network. The method, apparatus and computer program product may provide at least one security key for use in the subsequent network following handover from the initial network such that communications conducted via the subsequent network, including initial communications, may be secure. In order to provide at least one security key for use in the subsequent network, at least one security key of the initial network may be identified along with a nonce in response to a determination that a handover is to be made. The at least one security key of the subsequent network may then be determined based upon the at least one security key of the initial network and the nonce. | 09-02-2010 |
| 20110122801 | USER EQUIPMENT CAPABILITY BIASING - In accordance with the exemplary embodiments of the invention there is at least a method, apparatus, and executable computer program to perform operations including receiving at a user equipment information from a network access node, prioritizing capability information of the user equipment in accordance with the received information, and transmitting all or at least part of the prioritized capability information to the network access node. | 05-26-2011 |
| 20110274085 | Signaling radio bearer security handling for single radio voice call continuity operation - The exemplary embodiments of the invention provide at least a method, apparatus, and computer program to detect a single radio voice call continuity activation event indicating a handover of a user equipment between a packet switched domain and a circuit switched domain, consistent with a serving radio network subsystem relocation procedure, suspend control plane signaling radio bearers, reset the suspended signaling radio bearers, and resume the suspended signaling radio bearers in the domain handed over to, where resuming comprises protecting control plane signaling radio bearers of a domain handed over to using a same mapped security key that is used to cipher user plane radio access bearers in the domain handed over to. | 11-10-2011 |
