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| 20080228728 | GEOSPATIAL SEARCH METHOD THAT PROVIDES FOR COLLABORATION - A computer-implemented method involving a user communicating with a search engine that is also accessible by other users, the method involving: receiving a search query from the user and causing the search query to be submitted to the search engine; on a display device operated by the computer, displaying a multi-dimensional representation of a spatial domain along with search results supplied by the search engine in response to the search query; and on the display device, also displaying other information about the spatial domain, said other information including an indication of how many other users have previously viewed a representation that includes that spatial domain. | 09-18-2008 |
| 20080228729 | SPATIAL INDEXING OF DOCUMENTS - A computer-implemented method involving: gathering a set of files from one or more computers; analyzing the set of files to identify a plurality of files among the set of files that contain spatial information; storing information about the plurality of files, the stored information indicating that the identified files contain spatial information; and causing to be displayed to a user an indication that the identified files contain spatial information. | 09-18-2008 |
| 20080228754 | QUERY METHOD INVOLVING MORE THAN ONE CORPUS OF DOCUMENTS - A method of querying a first corpus of documents and a second corpus of documents, the method involving: accepting search criteria from a user, the search criteria including a free text entry query and a domain identifier identifying a domain; requesting a search of the first corpus of documents to identify a first set of documents, wherein each document of the first set of documents: (1) contains anywhere within the document location-related information that identifies a location within the domain; and (2) contains anywhere within the document information that is responsive to the free text entry query, wherein said identified documents are identified by a plurality of document identifiers; receiving a first result set for the first corpus of documents, the first result set identifying the first set of documents in order of relevance; requesting a search of the second corpus of documents to identify a second set of documents, wherein each document of the second set of documents: (1) contains anywhere within the document location-related information that identifies a location within the domain; and (2) contains anywhere within the document information that is responsive to the free text entry query, wherein said identified documents are identified by a plurality of document identifiers; receiving a second result set for the second corpus of documents, the second result set identifying the second set of documents in order of relevance; and merge sorting the first and second result sets to produce a new result set that is ordered in relevance. | 09-18-2008 |
| 20080270366 | USER INTERFACE FOR GEOGRAPHIC SEARCH - A computer-implemented method of processing a geotext query, said method involving: receiving a first free-text query string from a user; and decomposing the first free-text query into a non-geographic query and a geographic query, wherein the non-geographic query is a second free-text query string derived from the first free-text query string and the geographic query is a geographical location description. | 10-30-2008 |
| 20090119255 | Methods of Systems Using Geographic Meta-Metadata in Information Retrieval and Document Displays - A computer-implemented method involving a corpus of documents. The method includes accepting search criteria from a user, the search criteria including a domain identifier identifying a domain and including a filter condition specifying a geometric relationship between co-referenced locations; in response to accepting the search criteria from the user, searching among the corpus of documents to identify a set of documents, wherein each document among the set of documents contains anywhere within the document location-related information that refers to a location within the domain and satisfies the filter condition, and wherein the set of documents only includes documents that satisfy the filter condition; and identifying to the user the documents in the set of documents. | 05-07-2009 |
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| 20080242862 | Novel imidazo based heterocycles - The present invention is directed to novel imidazopyrazine compounds useful as kinase inhibitors and as such would be useful in treating certain conditions and diseases, especially inflammatory conditions and diseases and proliferative disorders and conditions, for example, cancers. | 10-02-2008 |
| 20080249305 | Novel imidazole based heterocycles - The present invention is directed to novel imidazopyrazine compounds useful as kinase inhibitors and as such would be useful in treating certain conditions and diseases, especially inflammatory conditions and diseases and proliferative disorders and conditions, for example, cancers. | 10-09-2008 |
| 20090270402 | Novel triazolopyridazines - The present invention is directed to novel compounds of formula (I) | 10-29-2009 |
| 20090312338 | Novel Tricyclic Compounds - The invention provides a compound of Formula (I) | 12-17-2009 |
| 20110190489 | Novel Tricyclic Compounds - The invention provides a compound of Formula (Ia), (Ib), (Ic), (Id), (Ie), (If), (Ig), (Ih), (Ii), (Ij), (Ik), or (Il) as defined herein, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions. | 08-04-2011 |
| 20110311474 | Novel Tricyclic Compounds - The invention provides compounds of Formula (I) and Formula (II) | 12-22-2011 |
| Patent application number | Description | Published |
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| 20090117117 | TARGETING ABCB5 FOR CANCER THERAPY - The invention relates to methods for treating a subject by manipulating ABCB5 on a cell as well as related products. The methods include methods of treating cancer using ABCB5 binding molecules such as antibodies and fragments thereof. | 05-07-2009 |
| 20090162873 | GENE ENCODING A MULTIDRUG-RESISTANCE HUMAN P-GLYCOPROTEIN HOMOLOGUE ON CHROMOSOME 7P15-21 AND USES THEREOF - The invention relates to an MDR family P-glycoprotein located on human chromosome 7p15-21, polynucleotide sequences encoding this P-glycoprotein and fragments thereof. This gene is utilized in methods for assessing cancer cell s susceptibility to therapies directed against multidrug resistance, and for the design of diagnostic and therapeutic methods relating to cancer multidrug resistance. The invention also relates to methods for determining whether a test compound may inhibit multidrug resistance. | 06-25-2009 |
| 20100145030 | GENE ENCODING A MULTIDRUG RESISTANCE HUMAN P-GLYCOPROTEIN HOMOLOGUE ON CHROMOSOME 7P15-21 AND USES THEREOF - The invention relates to an MDR family P-glycoprotein located on human chromosome 7p15-21, polynucleotide sequences encoding this P-glycoprotein and fragments thereof. This gene is utilized in methods for assessing cancer cell susceptibility to therapies directed against multidrug resistance, and for the design of diagnostic and therapeutic methods relating to cancer multidrug resistance. The invention also relates to methods for determining whether a test compound may inhibit multidrug resistance. | 06-10-2010 |
| 20110165149 | TARGETING ABCB5 FOR CANCER THERAPY - The invention related to methods for treating a subject by manipulating ABCB5 on a cell as well as related products. The methods include methods of treating cancer using ABCB5 binding molecules such as antibodies and fragments thereof. | 07-07-2011 |
| 20110287034 | THERAPEUTIC AND DIAGNOSTIC METHODS RELATING TO CANCER STEM CELLS - Genes that are deregulated in cancer stem cells (e.g., melanoma stem cells) are disclosed. Methods which involve modulating (e.g., inducing, inhibiting, etc.) the activity of the cancer stem cell associated genes are used to treat individuals having melanoma. Cell surface genes that are upregulated in melanoma stem cells are targeted for the selective isolation, detection, and killing of cancer stem cells in melanoma. | 11-24-2011 |
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| 20100162028 | VIRTUAL PROCESSOR METHODS AND APPARATUS WITH UNIFIED EVENT NOTIFICATION AND CONSUMER-PRODUCED MEMORY OPERATIONS - The invention provides, in one aspect, a virtual processor that includes one or more virtual processing units. These virtual processing units execute on one or more processors, and each virtual processing unit executes one or more processes or threads (collectively, “threads”). While the threads may be constrained to executing throughout their respective lifetimes on the same virtual processing units, they need not be. An event delivery mechanism associates events with respective threads and notifies those threads when the events occur, regardless of which virtual processing unit and/or processor the threads happen to be executing on at the time. The invention provides, in other aspects, virtual and/or digital data processors with improved dataflow-based synchronization. A process or thread (collectively, again, “thread”) executing within such processor can execute a memory instruction (e.g., an “Empty” or other memory-consumer instruction) that permits the thread to wait on the availability of data generated, e.g., by another thread and to transparently wake up when that other thread makes the data available (e.g., by execution of a “Fill” or other memory-producer instruction). | 06-24-2010 |
| 20100228954 | GENERAL PURPOSE EMBEDDED PROCESSOR - The invention provides an embedded processor architecture comprising a plurality of virtual processing units that each execute processes or threads (collectively, “threads”). One or more execution units, which are shared by the processing units, execute instructions from the threads. An event delivery mechanism delivers events—such as, by way of non-limiting example, hardware interrupts, software-initiated signaling events (“software events”) and memory events—to respective threads without execution of instructions. Each event can, per aspects of the invention, be processed by the respective thread without execution of instructions outside that thread. The threads need not be constrained to execute on the same respective processing units during the lives of those threads—though, in some embodiments, they can be so constrained. The execution units execute instructions from the threads without needing to know what threads those instructions are from. A pipeline control unit which launches instructions from plural threads for concurrent execution on plural execution units. | 09-09-2010 |
| 20110145626 | VIRTUAL PROCESSOR METHODS AND APPARATUS WITH UNIFIED EVENT NOTIFICATION AND CONSUMER-PRODUCED MEMORY OPERATIONS - The invention provides, in one aspect, a virtual processor that includes one or more virtual processing units. These virtual processing units execute on one or more processors, and each virtual processing unit executes one or more processes or threads (collectively, “threads”). While the threads may be constrained to executing throughout their respective lifetimes on the same virtual processing units, they need not be. An event delivery mechanism associates events with respective threads and notifies those threads when the events occur, regardless of which virtual processing unit and/or processor the threads happen to be executing on at the time. The invention provides, in other aspects, virtual and/or digital data processors with improved dataflow-based synchronization. A process or thread (collectively, again, “thread”) executing withing such processor can execute a memory instruction (e.g., and “Empty” or other memory-consumer instruction) that permits the thread to wait on the availability of data generated, e.g., by another thread and to transparently wake up when that other thread makes the data available (e.g, by execution of a “Fill” or other memory-producer instruction). | 06-16-2011 |
