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Franco, CA

Alessandra Franco, San Diego, CA US

Patent application numberDescriptionPublished
20110045046GLYCOPEPTIDES AND METHODS OF MAKING AND USING THEM - In one embodiment, the invention provides glycopeptides (or carbohydrate-peptide conjugates) comprising TACAs that direct against (e.g., bind specifically to) cytotoxic T lymphocytes (CTLs) or helper T cells for, e.g., CTL- or T-helper-based immunotherapy of carcinomas, and methods for making and using the glycopeptides of the invention. In one embodiment, the invention provides novel glycopeptides comprising tumor-derived carbohydrate or tumor-derived epitopes that specifically bind to major histocompatibility (MHC) class I molecules on cytotoxic T lymphocytes (CTLs) or MHC molecules on helper T cells, and methods for using same, e.g., as a vaccine, including a pan-cancer vaccine.02-24-2011

David Franco, Irvine, CA US

Patent application numberDescriptionPublished
20110060212METHODS AND APPARATUS FOR FLOW RESTORATION - Methods for restoring blood flow in occluded blood vessels using an apparatus having a self expandable distal segment that is pre-formed to assume a superimposed structure in an unconstrained condition but can be made to take on a volume-reduced form making it possible to introduce it with a microcatheter and a push wire arranged at the proximal end, with the distal segment in its superimposed structure assuming the form of a longitudinally open tube and having a mesh structure of interconnected strings or filaments or struts. In a preferred embodiment, the distal segment has a tapering structure at its proximal end where the strings or filaments or struts converge at a connection point.03-10-2011

Edward D. Franco, San Mateo, CA US

Patent application numberDescriptionPublished
20100295689Systems and Methods for Automated, Rapid Detection of High-Atomic-Number Materials - The present invention is directed to an inspection system that has a radiation source, a detector array, an inspection region, and a processing unit, where the processing unit a) obtains a radiographic image, b) segments the radiographic image based on radiation attenuation or transmission, c) identifies at least one segmented area on the radiographic image, d) filters the at least one segmented area using at least one geometric filter, e) generates feature vectors using the filtered segmented area; and f) compares the feature vectors against predefined values to determine whether a high-atomic-number object is present.11-25-2010

Hector Franco, Sunnyvale, CA US

Patent application numberDescriptionPublished
20120009894COLLABORATIVE INCIDENT ALERT SYSTEM FOR MOBILE DEVICES - An incident alert system enables a plurality of users to participate in a collaborative process to report and be alerted of incidents such as emergencies or hazards. A user uses a networked mobile phone with geo-positioning capability to communicate with a server to report incidents and to inquire about potential incidents of interest based on the user's current geographic position. Reports of incidents are transmitted to the server accompanied by the current position of the user/mobile phone. A user's mobile phone is preferably configured to automatically submit periodic inquiries to the server based on the user's location. Upon receipt of an inquiry from a user, the system queries a database to identify reports of potential interest to the inquiring user. The system analyzes the reports to determine whether to alert the inquiring user of a potential incident of interest.01-12-2012

Horacio Franco, Menlo Park, CA US

Patent application numberDescriptionPublished
20100125458METHOD AND APPARATUS FOR ERROR CORRECTION IN SPEECH RECOGNITION APPLICATIONS - In one embodiment, the present invention is a method and apparatus for error correction in speech recognition applications. In one embodiment, a method for recognizing user speech includes receiving a first utterance from the user, receiving a subsequent utterance from the user, and combining acoustic evidence from the first utterance with acoustic evidence from the subsequent utterance in order to recognize the first utterance. It is assumed that, if the first utterance has been incorrectly recognized on a first attempt, the user will repeat the first utterance (or at least the incorrectly recognized portion of the first utterance) in the subsequent utterance.05-20-2010

Patent applications by Horacio Franco, Menlo Park, CA US

John A. Franco, Emeryville, CA US

Patent application numberDescriptionPublished
20080221458Catheter and method for diagnosis and treatment of diseased vessels - The present invention provides a catheter for detecting and treating diseased tissue in a blood vessel or other hollow body organ. The catheter comprises an elongated tubular catheter shaft having a distal end comprising a light transmission zone. A first fiber lumen in the catheter shaft contains a diagnostic optical fiber having a distal end terminating within the light transmission zone for emitting and receiving light through the light transmission zone. A diagnostic subassembly at the proximal end and in communication with the diagnostic optical fiber processes diagnostic light for use in connection with a diagnostic method for detecting diseased tissue. A second fiber lumen can be provided in the catheter shaft for containing a treatment optical fiber for delivering treatment light from a light source at the proximal end of the catheter shaft to the light transmission zone. The treatment optical fiber has a distal end terminating within the light transmission zone for emitting light for treatment of the diseased tissue. An occlusion balloon is positioned on the distal end of the catheter shaft adjacent to the light transmission zone and in fluid communication with an inflation lumen. One or more infusion ports formed on or near the light transmission zone and in fluid communication with an infusion lumen deliver infusion fluid to the hollow body organ.09-11-2008

Justina A. Franco, Oxnard, CA US

Patent application numberDescriptionPublished
20110071567ARTICULATING SUTURING AND DEVICE AND METHOD - Devices, systems, and methods for suturing of body lumens allow the suturing of vascular puncture sites located at the distal end of a percutaneous tissue tract. An elongated articulated foot near a distal end of a shaft is inserted through the penetration and actuated so that the foot extends along the lumenal axis. The foot carries suturing attachment cuffs, and needles are advanced from the shaft through the vessel wall outside of the penetration and into engagement with the needle cuffs after the foot has been drawn proximally up against the endothelial surface of the blood vessel. The cross-section of the shaft within the tissue tract can be minimized by laterally deflecting the needles as they leave the shaft, while tapered depressions within the foot can guide the advancing needles into engagement with the cuffs. The cuffs lockingly engage the needles and can be withdrawn proximally along the needle paths and through the tissue tract so as to form a loop of suture across the puncture. The articulating foot may be realigned with the shaft and withdrawn proximally through the tissue tract without dilating the tissue tract.03-24-2011

Michael Anthony Franco, Long Beach, CA US

Patent application numberDescriptionPublished
20090294309APPARATUS AND PROCESS FOR HOLDING AT LEAST TWO CONSUMER GOODS - An apparatus and process for holding at least two consumer goods comprising a holder comprising a first surface, a second surface, and an edge between the first surface and the second surface. An apparatus and process for holding at least two consumer goods comprising a holder comprising a surface wherein the surface comprises a first side edge, a second side edge, a proximal end, and a distal end.12-03-2009

Ricardo Franco, San Jose, CA US

Patent application numberDescriptionPublished
20090156929METHODS FOR IMAGING A DELIVERY SYSTEM - A method for imaging a delivery system is disclosed. The method includes positioning an implantable device within a delivery apparatus. The implantable device has a first base material that includes a mixture of which a first radiopaque material is a component and/or coating at least a portion of the first base material with a coating of which a first radiopaque material is a component. The delivery apparatus may be positioned relative to an imaging device. An image produced by the imaging device may be analyzed. It may be determined whether the delivery apparatus is ready to deploy an implantable device.06-18-2009

Walfre Franco, Foster City, CA US

Patent application numberDescriptionPublished
20100211060RADIO FREQUENCY TREATMENT OF SUBCUTANEOUS FAT - A method for treating subcutaneous fat with RF energy is disclosed. The method includes determining a thickness of a layer of fat of a portion of tissue to be treated. Based on the determined thickness, an RF frequency is selected. In particular, lower frequencies are used for thicker layers of fat while higher frequencies are used for thinner layers of fat. RF heating is applied to the portion of the tissue by applying RF energy at the selected RF frequency.08-19-2010