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Francesca Benedini
Francesca Benedini, Bresso (milano) IT
| Patent application number | Description | Published |
|---|---|---|
| 20110092590 | NITRIC OXIDE DONATING PROSTAMIDES - Nitroderivatives of prostaglandins having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension. | 04-21-2011 |
Francesca Benedini, San Donato Milanese (madrid) ES
| Patent application number | Description | Published |
|---|---|---|
| 20100286264 | COMPOSITION COMPRISING A NITROOXYDERIVATIVE OF ACETAMINOPHEN AND A ANTICONVULSANT DRUG FOR THE TREATMENT OF NEUROPATHIC PAIN - The present invention relates to compositions comprising a nitric oxide releasing paracetamol and an anticonvulsant drug. The compositions of the invention can be used use in the treatment of neuropathic pain in particular diabetic neuropathic pain, painful post-infarct syndrome, pain caused by chemotherapeutic treatment or pain arising from infections by viral agents. | 11-11-2010 |
Francesca Benedini, San Donato Milanese IT
| Patent application number | Description | Published |
|---|---|---|
| 20080318965 | Derivatives of Alpha2-Adrenergic Receptor Agonist - The present invention relates to alpha | 12-25-2008 |
| 20100041633 | NITRIC OXIDE RELEASING STEROIDS - The invention relates to nitrooxyderivative of corticosteroids of general formula (I) and pharmaceutically acceptable salts or stereoisomers thereof wherein R is a corticosteroid residue selected from: The compounds are useful in the treatment of respiratory diseases. | 02-18-2010 |
| 20100093685 | NITRIC OXIDE RELEASING STEROIDS - The invention relates to nitrooxyderivative of corticosteroids of general formula (I) and pharmaceutically acceptable salts or stereoisomers thereof | 04-15-2010 |
| 20100152274 | CRYSTALLINE FORMS OF ATORVASTATIN 4-(NITROOXY) BUTYL ESTER - The present invention relates to two crystalline forms designated as form A and form B, of (βR,δR)-2(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbon-yl]-1H-pyrrole-1-heptanoic acid 4-(nitrooxy)butyl ester (atorvastatin 4-(nitrooxy)butyl ester), represented by the formula (I), The invention also relates to processes for the preparation of the forms A and B, to pharmaceutical compositions comprising the two forms, and to their use for treating and/or preventing acute coronary syndromes, stroke, neurodegenerative disorders, such as Alzheimer's and Parkinson's disease as well as autoimmune diseases, such as multiple sclerosis. | 06-17-2010 |
| 20100179192 | USE OF NITRIC OXIDE RELEASING COMPOUNDS IN THE TREATMENT OF CHRONIC PAIN - The present invention relates to nitrooxyderivative of antioxidant compounds of formula (I) and pharmaceutically acceptable salts or stereoisomers thereof for the treatment of chronic pain, in particular chronic neuropathic pain. The invention also describes composition comprising a nitrooxyderivative of a antioxidant compound of formula (I) and an analgesic drugs. | 07-15-2010 |
| 20100234334 | NITRIC OXIDE RELEASING STEROIDS - The invention relates to nitrooxyderivative of corticosteriods of general formula (I) and pharmaceutical acceptable salts or stereoisomers thereof wherein R is the corticosteriod residue of formulas (II): The compounds are useful in the treatment of respiratory diseases, inflammatory diseases, dermatological disease and ocular diseases. | 09-16-2010 |
Francesca Benedini, Milano IT
| Patent application number | Description | Published |
|---|---|---|
| 20090030076 | PROSTAGLANDIN DERIVATIVES - Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension. | 01-29-2009 |
| 20090062296 | Prostaglandin derivatives - Nitroderivatives of prostaglandin amides having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension. | 03-05-2009 |
| 20090075952 | NITRODERVIATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS - Use for the treatment of diseases having an inflammatory basis of compounds or salts thereof, having the following general formula (I): A-X | 03-19-2009 |
| 20100130507 | PROSTAGLANDIN DERIVATIVES - Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension. | 05-27-2010 |
| 20100217028 | PROCESS FOR PREPARING NITROOXYALKYL SUBSTITUTED ESTERS OF CARBOXYLIC ACIDS, INTERMEDIATES USEFUL IN SAID PROCESS AND PREPARATION THEREOF - The present invention refers to a process for preparing a compound of general formula (A), as reported in the description, wherein R is a radical of a drug and R1-R12 are hydrogen or alkyl groups, m, n, o, q, r and s are each independently an integer from 0 to 6, and p is 0 or 1, and X is O, S, SO, SO2, NR13 or PR13 or an aryl, heteroaryl group, said process comprising reacting a compound of formula (B) R—COOZ (B) wherein R is as defined above and Z is hydrogen or a cation selected from: Li+, Na+, K+, Ca++, Mg++, tetralkylammonium, tetralkylphosphonium, with a compound of formula (C), as reported in the description, wherein R1-R12 and m, n, o, p, q, r, s are as defined above and Y is a suitable leaving group. | 08-26-2010 |
| 20110136904 | PROSTAGLANDIN DERIVATIVES - Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension. | 06-09-2011 |
Francesca Benedini, San Donato Milanese (milano) IT
| Patent application number | Description | Published |
|---|---|---|
| 20100063035 | CARBONIC ANHYDRASE INHIBITORS DERIVATIVES - Nitroderivatives of dorzolamide and brinzolamide having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma, ocular hypertension, age-related macular degeneration, diabetic macular edema, diabetic retinopathy, hypertensive retinopathy and retinal vasculopathies. | 03-11-2010 |
| 20110130375 | NEW NO-RELEASING STEROIDS FOR THE TREATMENT OF RETINA AND MACULA LUTEA DISEASES - The invention relates to compounds of general formula (I) and pharmaceutically acceptable salts or stereoisomers thereof | 06-02-2011 |
| 20110130376 | NEW NO RELEASING STEROIDS DERIVATIVES - The invention relates to compounds of general formula (I) and pharmaceutically acceptable salts or stereoisomers thereof | 06-02-2011 |
| 20110144073 | GLUCOCORTICOIDS ATTACHED TO NITRATE ESTERS VIA AN AROMATIC LINKER IN POSITION 21 AND THEIR USE IN OPHTHALMOLOGY - The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea. | 06-16-2011 |
Francesca Benedini, San Donato Milanese (mi) IT
| Patent application number | Description | Published |
|---|---|---|
| 20090258849 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 10-15-2009 |
| 20090264393 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 10-22-2009 |
| 20090264394 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 10-22-2009 |
Francesca Benedini, San Donato Milanese(mi) IT
| Patent application number | Description | Published |
|---|---|---|
| 20080221073 | Nitrooxy Derivatives of Glucocorticoids - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 09-11-2008 |