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Frances H. Arnold, La Canada US

Frances H. Arnold, La Canada, CA US

Patent application numberDescriptionPublished
20090061471Methods and systems for selective fluorination of organic molecules - A method and system for selectively fluorinating organic molecules on a target site wherein the target site is activated and then fluorinated are shown together with a method and system for identifying a molecule having a biological activity.03-05-2009
20090124515METHODS AND COMPOSITIONS FOR PREPARATION OF SELECTIVELY PROTECTED CARBOHYDRATES - The disclosure relates to engineered P450 polypeptides and use of such polypeptides in chemoenzymatic methods to construct selectively protected carbohydrates, which are useful as building blocks for preparation of carbohydrate derivatives and oligosaccharides05-14-2009
20090142821Peroxide-driven cytochrome P450 oxygenase variants - The invention relates to novel variants of cytochrome P450 oxygenases. These variants have an improved ability to use peroxide as an oxygen donor as compared to the corresponding wild-type enzyme. These variants also have an improved thermostability as compared to the cytochrome P450 BM-3 F87A mutant. Preferred variants include cytochrome P450 BM-3 heme domain mutants having 158V, F87A, H100R, F107L, A135S, M145A/V, N239H, S274T, L3241, I366V, K434E, E442K, and/or V446I amino acid substitutions.06-04-2009
20090209010METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES - A method and system for selectively fluorinating organic molecules on a target site wherein the target site is activated and then fluorinated are shown together with a method and system for identifying a molecule having a biological activity.08-20-2009
20090298148REGIO- AND ENANTIOSELECTIVE ALKANE HYDROXYLATION WITH MODIFIED CYTOCHROME P450 - Cytochrome P450 BM-3 from 12-03-2009
20100255542POLYPEPTIDES HAVING CELLULASE ACTIVITY - The present disclosure relates to CBH II chimera fusion polypetides, nucleic acids encoding the polypeptides, and host cells for producing the polypeptides.10-07-2010
20100304464STABLE, FUNCTIONAL CHIMERIC CELLOBIOHYDROLASES - The present disclosure relates to CBH II chimera fusion polypeptides, nucleic acids encoding the polypeptides, and host cells for producing the polypeptides.12-02-2010
20110244537REGIO- AND ENANTIOSELECTIVE ALKANE HYDROXYLATION WITH MODIFIED CYTOCHROME P450 - Cytochrome P450 BM-3 from 10-06-2011

Patent applications by Frances H. Arnold, La Canada, CA US