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Fox, GB

Adrian Fox, West Yorkshire GB

Patent application numberDescriptionPublished
20090107644Dry Strength System for the Production of Paper and Board - The instant invention relates to certain cross-linked polyamides and their use in the paper and board industry for improving dry strength. The polyamide from the reaction of a di- or tri-primary amine with a di- or tri- or tetra carboxylic acid is further reacted with a di- or tri-functional cross-linking compound to give a cationic or anionic product with no reactive groups.04-30-2009

Alyson Fox, West Sussex GB

Patent application numberDescriptionPublished
20100144740SYNERGISTIC COMBINATIONS OF VR-1 ANTAGONISTS AND COX-2 INHIBITORS - A synergistic combination of a vanilloid receptor VR-1 antagonist and an NSAID or a pharmaceutically acceptable salt or solvate of either or both compounds thereof.06-10-2010

Alyson Fox, London GB

Patent application numberDescriptionPublished
20080207565USE OF BISPHOSPHONATES FOR PAIN TREATMENT - A method for the treatment of pain, in particular antinociceptive or anti-allodynic treatment of pain, in a patient in need of such treatment, e.g. a patient with osteoporosis or osteopenia, a tumour patient or a patient suffering from an inflammatory disease, which comprises administering an effective amount of a bisphosphonate, e.g. zoledronic acid or salts or hydrates thereof, to the patient08-28-2008

Alyson Fox, Horsham GB

Patent application numberDescriptionPublished
20090054404USE OF R-10-HYDROXY-10,11-DIHYDRO-CARBAMAZEPINE IN NEUROPATHIC PAIN02-26-2009
20100120746USE OF R-10-HYDROXY-10,11-DIHYDRO-CARBAMAZEPINE IN NEUROPATHIC PAIN - The present invention relates to the use of a mixture of the enantiomers of a compound of formula I05-13-2010

Andrew John Fox, Wiltshire GB

Patent application numberDescriptionPublished
20080246663Antenna Arrangement - An antenna has multiple antenna elements, with a beam forming Butler matrix, having antenna ports and input/output ports, with each of said antenna elements being connected to a respective port of the beam forming Butler matrix. Transceiver circuitry is connected to each of the input/output ports of the beam forming matrix by means of respective distinct transmit and receive paths and a respective duplexer. Individually controllable gain control elements are located in each of the transmit and receive paths. These can be controlled in response to signal strength measurements made by the antenna.10-09-2008
20100067392WIRELESS COMMUNICATION SYSTEM - An access point allows access from at least one user device, which may be a wireless device or a wired local area network device. The access point has radio frequency transceiver circuitry for communicating over a wireless link with a base station selected from a plurality of available base stations, and an antenna, having an adjustable preferred direction for transmission and reception of radio frequency signals. Control circuitry selects a preferred direction for the antenna such that the access point can establish a wireless link with one of said base stations, based on a data rate that is available over the wireless link.03-18-2010

Arnold Jeffrey Fox, Salford Lancashire GB

Patent application numberDescriptionPublished
20090090149Combination lock - A combination lock comprises a bolt which is withdrawn by depressing a bolt pin which is shielded by rotating discs having a movable disc pin within them. A selector pin attached to dial means is provided for engaging in selector holes in the discs and aligning the disc pins with one another and with the bolt pin, means being provided for pushing inwardly the disc pin on the outer disc and urging the other disc pins aligned therewith towards the bolt pin such that it is depressed and/or withdrawn. The discs have a weight attached at their circumference such that, during code setting, changing the position of the weight changes the relative angular position of the disc pin. When pressure is released from the mechanism, springs return the selector pin and the disc pins to their original positions and the weights on the discs fall, thereby rotating the discs and automatically scrambling the code.04-09-2009

Craig Fox, Essex GB

Patent application numberDescriptionPublished
20090191217Anti-IL-1R1 Single Domain Antibodies And Therapeutic Uses - Disclosed is the use of an antagonist of Interleukin 1 receptor type 1 (IL-1R1) for the manufacture of a medicament treating, preventing or suppressing lung inflammation or a respiratory disease. In some embodiments of the described invention, the medicament is for local administration to pulmonary tissue. Also disclosed are methods for treating lung inflammation or a respiratory disease.07-30-2009
20110053986RESPIRATORY DISEASE TREATMENT - There is provided a pharmaceutical composition that is adapted for pulmonary administration by inhalation, which composition comprises a glitazone, such as pioglitazone or rosiglitazone, and one or more pharmaceutically acceptable carriers and/or excipients, and wherein the glitazone content of the composition consists of at least 95% by weight of the 5R enantiomer and less than 5% by weight of the 5S enantiomer. There is also provided a use and kit.03-03-2011
20120041043Sulfonamide Compounds for the Treatment of Respiratory Disorders - Compounds of formula (I) are agonists of PPARγ, useful for the treatment of respiratory disease; formula (I): wherein R02-16-2012

Patent applications by Craig Fox, Essex GB

Craig Fox, Harlow GB

Patent application numberDescriptionPublished
20080318912Medicaments for Treating Chronic Respiratory Disease - There is provided the use of a methylxanthine compound and a steroid in a synergistic combination for the treatment of a respiratory disease, wherein the methylxanthine compound is administered at a dose, which, in isolation, is not effective to treat said disease.12-25-2008

David Fox, Banbury GB

Patent application numberDescriptionPublished
20100324089Anti-inflammatory composition - The invention relates to 3-(2′,2′-dimethylpropanoylamino)-tetrahydropyridin-2-one, and its pharmaceutical compositions and its use for preparing a medicament intended to prevent or treat inflammatory disorders.12-23-2010

David Fox, Berkshire GB

Patent application numberDescriptionPublished
20100240368CONTROLLING RESELECTION IN A TELECOMMUNICATIONS NETWORK - A base station reselection method for a mobile terminal camped on a base station, which mobile terminal performs a cell reselection function in accordance with reselection parameters. The method characterised by according a different priority to respective radio resource types and varying the reselection parameters in dependence upon the radio resource type of the base station on which the mobile terminal is camped to cause the mobile terminal to preferentially reselect to a higher priority radio resource type when available. A further base station reselection method includes determining radio characteristics of at least one neighbouring base station at a frequency, characterised by varying the frequency at which said radio characteristics are determined in dependence upon the rate of movement of the mobile terminal.09-23-2010
20100246503REDUCING INTERFERENCE IN A TELECOMMUNICATIONS NETWORK - Controlling interference in a telecommunications network, in which data are transmitted between mobile devices and base stations in resource blocks, includes, for each of the base stations: allocating resource blocks to one of multiple resource groups, the corresponding resource blocks of each base station being in the same resource group; allocating resource groups to one of multiple transmission power values, the corresponding resource groups of each base station having different transmission power values; and allocating respective ones of the mobile devices to one of the resource groups depending upon a UE characteristic. Interference at a resource block of a resource group of a base station caused by a neighbouring base station is detected. In response thereto, an indication of the resource group subject to interference is sent to the neighbouring base station and then the transmission power value of said resource group of the neighbouring base station is selectively reduced.09-30-2010
20110199927TELECOMMUNICATIONS NETWORKS - An SAE/LTE or 4G cellular telecommunications network is disclosed which comprises a plurality of eNodeBs 08-18-2011

David Andrew Fox, Berkshire GB

Patent application numberDescriptionPublished
20110222450TELECOMMUNICATIONS SYSTEM AND METHOD - In a telecommunications network including a mobile terminal configured to operate in at least one active state and an idle mode, a network element for, and method of, managing the mobile terminal's duration of operation in the least one active state, which determine a parameter relating to the mobile terminal or a user of the mobile terminal; allocate an state transition timer with a particular duration in dependence upon the parameter; and transition the mobile terminal to a lesser active state or idle mode upon expiry of the state transition timer. The active states are preferably the RRC states of CELL_DCH, CELL_FACH, URA_PCH and CELL_PCH and the parameter is preferably a Quality of Service indication such as subscriber classification.09-15-2011

David Andrew Fox, Newbury GB

Patent application numberDescriptionPublished
20100190497Telecommunications network access rejection - A method of controlling an attach procedure of a device 07-29-2010
20100222058Telecommunications system and method - In a mobile telecommunications network including at least a first type of radio access network and a second type of radio access network and a mobile terminal, a method of establishing a voice communication with the mobile terminal including: receiving a voice communication request in relation to the mobile terminal on the second radio access network type; determining a parameter associated with a terminal characteristic; and using the parameter to determine whether to establish the voice communication on the first type of radio access network or maintain the voice communication on the second type of radio access network. Preferably the determined parameter is a parameter relating to a terminal type for the mobile terminal, and is determined from the terminal's IMEI.09-02-2010
20110069618Circuit-switched services over LTE - A mobile radio communication system and method of initiating a circuit-switched service at a mobile station over a System Architecture Evolution (SAE) core network using packet-switched communications between the mobile station and the SAE core network is provided. The method includes communicating service handling information between a Mobile Switching Centre (MSC) and the mobile station through a Mobility Management Entity (MME) of the SAE core network; sending instructions from the MSC for setting up the circuit-switched service through a Media Gateway, coupled to at least one network external to the SAE core network; providing packet-switched addressing information for the Media Gateway to the mobile station; and initiating the circuit-switched service at the mobile station over the SAE core network and through the Media Gateway.03-24-2011
20110070906Telecommunication networks - A mobile telecommunications network includes a core and a radio access network having a wireless device for wireless communication with mobile terminals registered with the network, wherein the radio access network includes a controller operable to control the use of network resources by the mobile terminals. The controller may include an application programming interface (API) which provides a consistent interface to a multiplicity of applications hosted on the controller. The controller may be provided at an access node site and/or a gateway site.03-24-2011
20120064908Telecommunication networks - A mobile telecommunications network includes a core and a radio access network having a radio for wireless communication with mobile terminals registered with the network, wherein the radio access network includes a controller operable to control the use of network resources by the mobile terminals. The controller may include an application programming interface, API, which provides a consistent interface to a multiplicity of applications hosted on the control mean. The controller may be provided at an access node site and/or a gateway site.03-15-2012

Patent applications by David Andrew Fox, Newbury GB

David Nathan Abraham Fox, Sandwich GB

Patent application numberDescriptionPublished
20080293697Pyrazolo[4,3-D]Pyrimidines - This invention relates to compounds of formula (I).11-27-2008
20090247539Novel Pharmaceuticals - This invention relates to compounds of formula (I)10-01-2009

Patent applications by David Nathan Abraham Fox, Sandwich GB

Francis Kirkman Fox, Hampshire GB

Patent application numberDescriptionPublished
20080197972Traceability And Authentication Of Security Papers - A security paper such as a bank note has a data matrix printed or attached to it. The data matrix includes an encoded unique identifier for the security paper which may be read by a scanner and compared with a store of unique identifiers to authenticate the bank note. The remote store may include an indication as to whether or not the bank note is activated or whether it has not been issued or has been released from circulation. Data on the data matrix may be arranged in layers with a second layer containing further data associated with the bank note. The data in one or more layers may be encrypted using different encryption algorithms whereby different parties may have access to the data on different layers. RFID tags may be used in addition or as an alternative to data matrixes.08-21-2008
20080215489Method And Apparatus For Authentication Of Invoices - The security of invoices as between purchaser and supplier may be improved by printing a data matrix symbol or other glyph on the invoice. The data matrix contains two layers or portions of data. The first layer or portion contains invoice data and the second layer or portion contains secure data relating to the purchaser and supplier. This may include a trusted supplier status, a trusted supplier code and a unique voice identifier, or a reference thereto. On receipt of the invoice by the purchaser the data matrix is scanned and the trusted supplier status and supplier codes retrieved. These may be compared against a store of codes and status to verify the invoice as authentic. The secure data or a reference to the secure data may be re-encoded into a data matrix which may be affixed to a remittance advice sent by the purchaser to the supplier.09-04-2008
20080222042Prescription Generation Validation And Tracking - Medical prescriptions may be produced in electronic form and carry a plurality of encoded, encrypted data sets. The first data set may represent a unique prescription identifier and the second data set a patient identifier such as a PIN: Both data sets are encrypted and printed on the item, for example encoded in a data matrix. The patient may present a printed prescription to a chemist at which point the data matix symbol is canned to retrieve the encrypted data sets. The data set including the unique identifier may be sent to a remote location for decryption and comparison against a stored identifier to verify the prescription as genuine. The second data set may be decrypted and compared locally to verify that the person presenting the prescription is the patient or an authorised representative of the patient. If both data sets are vertified, the chemist maydispense the medicine. Further data sets may include details of the prescription and prescription history, and details of the doctor and the chemist. The latter two can be sent to local health authorities for payment. The doctor can be notified when the prescription is validated and the patient's records updated accordingly. Different encryption may be used for the two data sets.09-11-2008
20080224823Identification Systems - An identification system where providing' identification data sets that contain different types of information accessible by different parties, removes the need for all potential readers of the object to be able to access all information, and to contact a third party during the verification process is disclosed. The identification data sets are encrypted and printed in a portable physical form as an identity object. Graphical symbols, such as a data matrix, or RFID tags or secure chips may be used to store encrypted data. These may be incorporated into a passport or other identification document. Additional identity objects may be printed for use in identifying objects connected with a user or source that contain a subset of the information in the original data matrix.09-18-2008
20080255990On-Line Generation and Verification of Personalised Money - Personalised money may be produced on-line and carry an identifier having at least a first and a second data set. The first data set may represent a unique item identifier and the second data set other item related information. Both data sets are encrypted and printed on the money, for example encoded in a data matrix symbol. The user may present the printed money for redemption at which point the data matrix symbol is scanned to retrieve the encrypted data sets. The data set including the unique identifier may be sent to a remote location for decryption and comparison against a stored identifier. The second data set may be decrypted and compared locally. Different encryption may be used for the two data sets.10-16-2008
20090283589ON-LINE GENERATION AND AUTHENTICATION OF ITEMS - Items that require authentication, such as coupons or tickets are printed with a data carrier such as a data matrix or an RFID device. Encoded on the data carrier is a value based token, which comprises a header, a payload and a security portion. The header identifies the token type and also includes a unique identification of the token. A PIN flag may also be included. The payload may be encrypted and contain data which gives an authorised party access to a portion of a databases that stores information corresponding to the token identifier. The security portion may comprise a hash or a digital signature.11-19-2009
20090293112ON-LINE GENERATION AND AUTHENTICATION OF ITEMS - Value based tokens are generated for inclusion on a data carrier which may be applied to a media such as a coupon, bank note etc. The tokens are generated by a core system which communicates with application specific wrappers. The wrappers supply token parameters to the core that are specific to the application and the core generates the tokens, and stores them for later authentication. The core then encodes the tokens onto a data carrier under the control of the wrapper and distributes the tokens under the control of the wrapper. When a token is presented for validation, for example by a customer in a shop, the encoded data carrier is scanned and the token retrieved. It is passed back to the core by the wrapper for validation of its identification number and other parameters.11-26-2009

Glyn Charles Fox, Derbyshire GB

Patent application numberDescriptionPublished
20100158670COMBUSTOR RUMBLE - Apparatus and a method of detecting combustor rumble in a gas turbine engine having combustion equipment that is susceptible to combustor rumble. The method has steps of: 06-24-2010

Howard George Fox, West Sussex GB

Patent application numberDescriptionPublished
20080206237Synergistic Combination Of Xolair/Omalizumab/E25 With Immunosuppressive Agent - The present invention provides a pharmaceutical composition comprising an Anti-IgE Antibody and at least one further immunosuppressive agent, in which the active ingredients are present in each case in free form or in the form of a pharmaceutically acceptable salt and optionally at least one pharmaceutically acceptable carrier; for simultaneous, separate or sequential use.08-28-2008

James Fox, Cambridge GB

Patent application numberDescriptionPublished
20080252671Computerized Apparatus and Method for Applying Graphics to Surfaces - A system and method for applying an image to a substrate surface are disclosed. The method comprises receiving a set of color matrix maps representing color pixel overlays forming the image, effecting a positioning of a print head array relative to the substrate surface, the print head array comprising at least one print head having a plurality of nozzles, receiving real-time geometry data representing the print head array position and orientation in space, determining, in response to the real-time geometry data, the print head array position and orientation relative to the substrate surface, determining, in response to the print head array position and orientation relative to the substrate surface and the set of color matrix maps, a set of pixels to be applied by the print head array to the substrate surface, and generating instructions to the print head array, in response to the set of pixels to be applied, to actuate particular nozzles in the print head array to apply the set of pixels to the substrate surface.10-16-2008

James Edward Fox, Hertfordshire GB

Patent application numberDescriptionPublished
20120092424Inkjet Printers - An inkjet printhead (04-19-2012

James Edward Fox, Cambridge GB

Patent application numberDescriptionPublished
20080283275Metal Deposition - A method for electroless plating of metal on a laser-patterned substrate. A substrate is provided on which both a thermal imaging layer and catalytic layer are deposited. On exposure to a laser beam, sufficient levels of radiation are converted to heat in the thermal imaging layer to render the exposed regions of the adjacent catalytic layer inactive. The laser-patterned substrate is then exposed to a reaction solution which initiates the growth of a metal film on the unexposed regions of the catalytic layer.11-20-2008

Patent applications by James Edward Fox, Cambridge GB

Jeremy Wilfred Fox, Salford GB

Patent application numberDescriptionPublished
20110192664GROUND EFFECT LOAD TRANSPORTATION - A ground effect transport system comprising a plenum roof platform for location beneath a load carrying means, a skirt depending from the platform to form a plenum chamber with the platform, fan means on or in the platform for supplying air to the plenum chamber, wherein the skirt extends downwardly towards the ground surface and has a ground engaging support member for supporting the bottom of the skirt above the ground surface and a separate detachable sealing member for providing a seal between the bottom of the skirt and the ground surface.08-11-2011

Jonathan Fox, Shevington GB

Patent application numberDescriptionPublished
20090200802Clamp - A clamp is disclosed which is for mounting upon a cylindrical member such as a sub-sea riser or umbilical 08-13-2009

Justian Craig Fox, Essex GB

Patent application numberDescriptionPublished
20080318913Combination of Methylxanthine Compounds and Steroids to Treat Chronic Respiratory Diseases - There is provided the use of a methylxanthine derivative such as theophylline and a steroid in a synergistic combination for the treatment of chronic obstructive pulmonary disease, wherein the combination is administered by the inhaled route for pulmonary delivery.12-25-2008
20100034831Agents that Bind a Target in Pulmonary Tissue for Targeting Respiratory Diseases - Disclosed is the use of an agent (e.g., antibody fragment, antagonist, ligand, dAb monomer) that binds a target in pulmonary tissue for the manufacture of a long action or long therapeutic window formulation for local delivery to pulmonary tissue, and methods for administering an agent that binds a target in pulmonary tissue to a subject to produce a long therapeutic window in pulmonary tissue. The formulation is for, and the method comprises, administering locally to pulmonary tissue. Also disclosed is the use of antagonists of TNFR1 for the manufacture of a formulation or medicament for treating, preventing or suppressing lung inflammation or a respiratory disease, and methods of treating such diseases. Also disclosed are the use of agents a for the manufacture of a delivery device (e.g., inhaler, intranasal delivery device) for the treatment or prevention of lung inflammation or a respiratory disease, and a delivery device for the treatment or prevention of lung inflammation or a respiratory disease that contains an agent as described herein.02-11-2010

Justian Craig Fox, Harlow GB

Patent application numberDescriptionPublished
20100324002Inhaled combination therapy - There is provided the use of a methylxanthine derivative such as theophylline and a steroid in a synergistic combination for the treatment of chronic obstructive pulmonary disease, wherein the combination is administered by the inhaled route for pulmonary delivery.12-23-2010

Kevin Fox, Glasgow GB

Patent application numberDescriptionPublished
20110226642Carrier Apparatus - An apparatus for carrying one or more garments is described. The apparatus comprises a housing (09-22-2011

Kevin Fox, South Wales GB

Patent application numberDescriptionPublished
20100133138DRIP TRAY - A drip tray (06-03-2010

Marc Alan Fox, Salisbury GB

Patent application numberDescriptionPublished
20110237500CECROPIN-MAGAININ HYBRID PEPTIDES - The present invention relates to a biocidal fusion peptide of SEQ ID NO: 1 or a sequence with at least 90% identity thereto, compositions such as pharmaceutical compositions comprising the same, methods of preparing the peptide, and use of the peptide in treatment, in particular for the treatment of bacterial infection and/or fungal infection and/or viral infection.09-29-2011
20110288007BIOCIDAL FUSION PEPTIDE COMPRISING LL-37 - The present invention relates to a biocidal fusion peptide comprising: a) a peptide LL-37 or an active fragment or active derivative thereof; b) and a further heterologous bioactive peptide or an active fragment thereof, wherein part or all of the amino acid sequence of the fusion peptide is predicted to form an alpha-helix structure for disruption of a pathogen membrane, compositions such as pharmaceutical compositions comprising the same, methods of preparing the peptide and use of the peptides in treatment, in particular for the treatment of bacterial infection and/or fungal infection and/or viral infection.11-24-2011

Martin E. Fox, Herts GB

Patent application numberDescriptionPublished
20090099358BISPHOSPHOLANES FOR USE AS CATALYSTS IN ASYMMETRIC REACTIONS - The invention is a set of novel bisphospholane ligands that can be complexed with transition metals. These complexes are useful as catalysts in asymmetric reactions such as asymmetric hydrogenation.04-16-2009

Nicholas C. Fox, London GB

Patent application numberDescriptionPublished
20100260399SCANNER DATA COLLECTION - A scanning system comprises a scanner arranged to perform a scan of a subject to generate a scan data set; processing means arranged to receive the scan data set from the scanner, analyse the scan data set to determine whether it meets at least one criterion, and generate an output if it does not.10-14-2010

Robert Fox, Midlothian GB

Patent application numberDescriptionPublished
20120061969WIND TURBINE GENERATOR AND TIDAL CURRENT GENERATOR - An object of the present invention is to provide a wind turbine generator and a tidal current generator equipped with a hydraulic transmission with a combination of a hydraulic pump and a hydraulic motor and which has a superior productivity and maintainability. The wind turbine generator 03-15-2012

Robert George Fox, Peebles GB

Patent application numberDescriptionPublished
20120045327Fluid-Working Machine with Multi-Lobe Ring Cam - A fluid-working machine for a renewable energy generation device, the fluid-working machine comprising a ring cam and a plurality of working chambers, the ring cam having an annular working surface extending around an axis of rotation of the ring cam, the annular working surface defining a plurality of waves, each working chamber having a piston, each piston in operative engagement with the ring cam working surface, the ring cam and working chambers being mounted to rotate relative to each other, cycles of working chamber volume being thereby coupled to rotation of the ring cam relative to the working chambers, characterised in that the individual waves of the ring cam working surface have an asymmetric profile.02-23-2012
20120060685VARIABLE DISPLACEMENT RADIAL PISTON FLUID WORKING MACHINE - A variable displacement fluid working machine includes an inward ring and an outward ring, one of the inward ring and the outward ring including a rotatable ring cam coupled to a drive shaft, the other including a plurality of radially extending piston cylinders circumferentially spaced around the respective ring. The outward ring has first and second axially spaced structural members and a plurality of demountable blocks demountably retainable therebetween, the demountable blocks having either piston cylinders or ring cam segments. The demountable blocks are removable radially to facilitate maintenance and repair and to facilitate radial access to the inward ring.03-15-2012

Stewart Maddison Fox, Cambridge GB

Patent application numberDescriptionPublished
20090024057Catheter - A catheter for insertion into a blood vessel, the catheter having a sampling part arranged to capture a blood sample at a plurality of locations along a length of the blood vessel and an apparatus arranged to analyse blood taken from a plurality of locations along the length of the blood vessel and to provide a profile of concentration levels along the length of the blood vessel.01-22-2009
20110212478CATHETER - A catheter for insertion into a blood vessel, the catheter having a sampling part arranged to capture a blood sample at a plurality of locations along a length of the blood vessel and an apparatus arranged to analyse blood taken from a plurality of locations along the length of the blood vessel and to provide a profile of concentration levels along the length of the blood vessel.09-01-2011

Susan Carol Fox, Nottingham GB

Patent application numberDescriptionPublished
20110059475STABILISATION OF BLOOD CELL CONJUGATES - The invention relates to methods and kits for stabilising blood cell conjugates in blood samples for subsequent analysis. The invention particularly relates to methods and kits for use in fixing and stabilising platelet aggregates in blood samples, and methods for detecting the degree of platelet aggregation in a sample. The invention extends to kits for monitoring the efficacy of anti-thrombotic treatment regimes using platelet aggregation analysis. Two compositions with aliphatic aldehydes and a buffer are employed in a consecutive order. The second composition comprises addition a chelating agent.03-10-2011

Susna Carol Fox, Nottinghamshire GB

Patent application numberDescriptionPublished
20100105021STABILISATION OF BIOLOGICAL CELL MARKERS - The invention provides compositions which stabilise the expression of cell surface markers. The invention further provides methods and kits comprising such compositions for use in stabilising the expression of cell surface markers. The invention is especially concerned with compositions for use in stabilising the expression of cell surface markers (such as cell activation markers) present on blood cells, such as platelets. The invention extends to methods, apparatus and kits for detecting platelet activation, and to kits for monitoring the efficacy of anti-thrombotic treatment regimes.04-29-2010