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Foulkes

Graham S. Foulkes, Washington Township, MI US

Patent application numberDescriptionPublished
20090184533Vehicle Endgate Hinge Assembly - A vehicle endgate hinge assembly is disclosed. The hinge assembly has a bodyside hinge strap including a hinge support boss extending through the endgate opening shut-face and having a central hole that is coaxial with the endgate pivot axis, a mounting plate located outboard of the shut-face, and a threaded portion extending from the mounting plate through the shut-face. The hinge assembly may have a crank including a hinge key pivotally coupled to a member mounted on the endgate, a pivot shaft extending from the hinge key through the central hole, a lever arm extending from the pivot shaft normal to the endgate pivot axis, and a ball extending from the lever arm spaced from the endgate pivot axis. A nut is located inboard of the endgate opening shut-face and threadably received on the threaded portion, and an energy storage mechanism is coupled to the ball.07-23-2009
20100084885Viscous Rotary Damper for Vehicle End Gate Assembly - A viscous rotary damping device for a vehicle end gate assembly is provided. The damping device includes a housing member configured to operatively attach to the vehicle body or the end gate assembly. The housing member defines a fluid chamber having viscous fluid therein. The damping device also includes an impeller member having a mast with a first end configured to operatively attach to the other of the vehicle body and the end gate assembly, and a second end having one or more blades projecting outward therefrom. The second end of the mast is rotatably received in the fluid chamber such that the impeller member dissipates kinetic energy generated by the end gate assembly when transitioning between a first, closed position and a second, open position. A cover plate member is preferably coupled to the housing member, and configured to fluidly seal the fluid chamber.04-08-2010

J. Gordon Foulkes, Encinitas, CA US

Patent application numberDescriptionPublished
20100130595ANTISENSE OLIGONUCLEOTIDES DIRECTED AGAINST CONNECTIVE TISSUE GROWTH FACTOR AND USES THEREOF - This invention provides compounds which comprise modified oligonucleotides capable of inhibitory expression of connective tissue factor and composition containing same as well as methods of treating hyperprolific disorders and fibrotic diseases, and of reducing scarring resulting from wound healing using such compounds.05-27-2010
20110172296MODULATION OF TRANSFORMING GROWTH FACTOR-BETA 1 EXPRESSION - Provided are compounds capable of inhibiting expression of TGF-beta 1 and compositions containing same as well as methods using such compounds for treating fibrotic diseases including the reduction of scarring resulting from wound healing.07-14-2011

Patent applications by J. Gordon Foulkes, Encinitas, CA US

Michael Foulkes, Riehen CH

Patent application numberDescriptionPublished
20080207921Organic Compounds - The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula III,08-28-2008
20090018325PROCESS FOR PREPARING L-NUCLEIC ACID DERIVATIVES AND INTERMEDIATES THEREOF - A novel method has been found to produce 2,2′-anhydro-1-(β-L-arabinofuranosyl)thymine as a novel useful intermediate compound. A novel method has been further found to produce thymidine from 2,2′-anhydro-1-(β-L-arabinofuranosyl)thymine. According to these methods, synthesis of various L-nucleic acid derivatives, synthesis of which has been difficult till now, is possible.01-15-2009
20100168229Process for the preparation of optically active compounds using transfer hydrogenation - A catalytic process for the preparation of optically active compounds and their conversion thereafter to desired drug substances. In particular, the process relates to the preparation of (S)-3-(1-Dimethylamino-ethyl)-phenol using asymmetric catalytic reduction and transfer hydrogenation, thereby providing an improved route to forming drug substances such as rivastigimine and rivastigimine hydrogen tartrate.07-01-2010
20100274027ORGANIC COMPOUNDS - The invention provides a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Allskiren. Inter alia, the invention provides a process for the manufacture of a compound of the formula III,10-28-2010

Patent applications by Michael Foulkes, Riehen CH

Nicholas Foulkes, Chard GB

Patent application numberDescriptionPublished
20110201488CENTRIFUGAL SEPARATOR WITH SNAP FIT SEPARATION CONE - A separation cone (08-18-2011

Richard Foulkes, Hinsdale, IL US

Patent application numberDescriptionPublished
20100204786METHOD AND INSERT FOR MODIFYING EYE COLOR - A method and intrastroma insert are adapted to modify eye color. The insertion of opaque material into the stromal space is a means of changing the color and/or design of the stroma and, apparently, the iris. Biocompatible inserts include a slurry of biocompatible material, a fabric including opacified material, and a thin, permeable film material incorporating some opaque materials that may also alter the shape of the cornea to improve aberrational shape.08-12-2010

Stephen B. Foulkes, Fownhope GB

Patent application numberDescriptionPublished
20100250185Method for detection of gravitational anomalies - A method and system for detecting gravitational anomalies comprises measuring surface structures, measuring gravitational field characteristics, and estimating the effect of the surface structures on the gravitational measurements. The estimations are then used to derive a representation of nearby non visible features such as changes in rock density, voids, or oil and gas deposits. The surface structures may be measured by a video camera, with the video sequence being processed to estimate 3D positions of structures relative to the measurement point. Other methods may be used, such as lidar or acoustic techniques as appropriate. The method may be applied above ground and also has efficacy in borehole and sewer surveying applications.09-30-2010