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Foster, GB
Adrian Paul Foster, Kent GB
| Patent application number | Description | Published |
|---|---|---|
| 20080269310 | Synergistic Combinations - This invention relates to synergistic combinations of non-steroidal anti | 10-30-2008 |
Alison Jane Foster, Liverpool GB
| Patent application number | Description | Published |
|---|---|---|
| 20110217381 | PHARMACEUTICAL COMPOSITIONS - The present invention provides a substantially solvent-free nano-dispersion of an active in a carrier, wherein the carrier comprises an enteric carrier soluble at intestinal pH, but insoluble at stomach pH, and wherein the enteric carrier comprises at least 50% by weight of the nano-dispersion; and processes for the preparation of a substantially solvent-free nano-dispersion of an active in a carrier. | 09-08-2011 |
Beth M Foster, Bristol GB
| Patent application number | Description | Published |
|---|---|---|
| 20100209359 | MEDICATED CHEWING GUM - The present invention provides a chewing gum composition comprising a chewing gum base, a biologically active ingredient, a polymeric material and one or more sweetening and flavouring agents, wherein the polymeric material is amphiphilic, has a straight or branched chain carbon-carbon backbone and a multiplicity of side chains attached to the backbone. A method of making the chewing gum composition is also provided. | 08-19-2010 |
Brian Foster, Broadstone GB
| Patent application number | Description | Published |
|---|---|---|
| 20080261162 | Burner and method of burning gas in a furnace - A gas burner for use in a furnace and a method of burning gas in a furnace, especially but not exclusively a process furnace used in an oil cracking or refining process. The gas burner comprises two passageways with adjacent outlets. The first passage way is in fluid communication with a source of pressurized fuel gas and has an aperture through which recirculated flue gas can enter the first passageway and the second passageway is in fluid communication with a source of air. In operation, fuel gas is injected into the first passageway and recirculated flue gas is thereby drawn into the first passageway so that it mixes with the fuel gas. Fuel gas is partially combusted and a mixture of partially combusted fuel gas and recirculated flue gas flows up the first passageway and comes into contact with air from the second passageway and combusts. The use of recirculated flue gas keeps down the level of NOx emissions and as the recirculated flue gas is sucked into the first passageway by the pressurised fuel gas flow it is not necessary to provide complex pumping mechanisms. | 10-23-2008 |
Carole Lesley Foster, Berkshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20100231846 | Substrates - The present invention relates to improvements in security devices that can be used in varying shapes and sizes for various authenticating or security applications, particularly an optically variable security device utilising liquid crystal materials. The security device comprises a liquid crystal layer ( | 09-16-2010 |
Charles Foster, Henley-On-Thames GB
| Patent application number | Description | Published |
|---|---|---|
| 20100303458 | Optical Data Communications - A method of communicating data between a network device and a data network to which the device is connected via an optical fiber data link in which the device is connected to the optical fiber data link and the connection is monitored to detect data communication at a first standard. If data communication is detected at the first standard, data communication is established using the first standard. If not, the connection is monitored at the second standard. If data communication is detected at the second standard, data communication is established using the second standard. | 12-02-2010 |
Chris Foster, Bristol GB
| Patent application number | Description | Published |
|---|---|---|
| 20110215196 | ENGINE DEBRIS GUARD - An engine debris guard for preventing tyre propelled debris striking an aircraft engine, the debris guard comprising a guard bar pivotably connected to an aircraft main landing gear having at least one wheel and tyre assembly, the guard bar being arranged to be movable between a first position and a second position wherein in the first position the guard bar extends laterally across the wheel and tyre assembly to intersect the possible trajectories between the wheel and tyre assembly and an engine of the aircraft of any tyre propelled debris. | 09-08-2011 |
Clive Edwin Foster, Manchester GB
| Patent application number | Description | Published |
|---|---|---|
| 20090104417 | Magenta Dyes and Their Use in Ink-Jet Printing - A metal chelate compound comprising a compound of the Formula (1) or a salt thereof: | 04-23-2009 |
| 20110195236 | Disazo Dyes And Their Use in Ink-Jet Printing - A compound of Formula ( | 08-11-2011 |
| 20110200800 | Disazo Compounds and Their Use in Ink-Jet Printing - A compound of Formula (1) or a salt thereof: | 08-18-2011 |
| 20110242197 | Magenta Dyes and Inks for Use in Ink-Jet Printing - A compound of Formula (1) and salts thereof: | 10-06-2011 |
| 20120081456 | Magenta Dyes and Inks for Use in Ink-Jet Printing - An oligomerised dye compound, and salts thereof, obtainable by a process which comprises reacting a compound of Formula (1) and salts thereof with a compound of Formula (2) and salts thereof | 04-05-2012 |
Clive Edwin Foster, Blackley GB
| Patent application number | Description | Published |
|---|---|---|
| 20090297795 | Ink-Jet Printing Using Disazo Dyes - A compound of Formula (1) and salts thereof: | 12-03-2009 |
David Foster, Oxfordshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20100010495 | Medical Treatment Material Delivery Apparatus - A delivery apparatus for delivering material to a medical treatment site which comprises a plurality of containers for containing the material, a dispensing outlet and means for bringing each container into communication with the outlet and means for transferring material from the containers and through the outlet. The plurality of containers may be removably mounted within a removable cartridge. The apparatus is arranged so that the cartridge is biased to sequentially move each of the containers into communication with the outlet. The outlet may be provided at the end of a dispensing nozzle where the dispensing nozzle has an inner cross-sectional area that is uniform and the same as the containers so that no taper is provided as the material is dispensed from the containers and out of the outlet. | 01-14-2010 |
David Edward Foster, Worcestershire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090159555 | LINERLESS BORE SEAL CLOSURE - A closure ( | 06-25-2009 |
David Evans Foster, Cleveland GB
| Patent application number | Description | Published |
|---|---|---|
| 20090090429 | CATALYST LOADING APPARATUS - A method for loading a particulate catalyst into a vertical catalyst tube includes (i) introducing catalyst loading apparatus into a vertical catalyst tube, (ii) loading catalyst particles into the top of the tube whereinafter they contact the apparatus as they pass down the tube, forming a uniform bed of catalyst beneath the apparatus and (iii) simultaneously removing the apparatus from the catalyst tube in timed relationship to the catalyst loading, wherein the apparatus includes one or more deflector units, each deflector unit including a plurality of inclined deflector plates arranged on a rigid elongate member such that all the catalyst particles are deflected by one or more of the plates as they pass through the or each unit. | 04-09-2009 |
David J. Foster, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20090182320 | Cryosurgical System - A cryosurgical system using a low-pressure liquid nitrogen supply, which requires only 0.5 to 15 bar of pressure to provide adequate cooling power for treatment of typical breast lesions. The pressure may be provided by supplying lightly pressurized air into the dewar, by heating a small portion of the nitrogen in the dewar, or with a small low pressure pump. | 07-16-2009 |
| 20100198205 | Low Pressure Liquid Nitrogen Cryosurgical System - A cryosurgical system using a low-pressure liquid nitrogen supply, which requires only 0.5 to 1 bar of pressure to provide adequate cooling power for treatment of typical breast lesions. The pressure may be provided by supplying lightly pressurized air into the dewar, by heating a small portion of the nitrogen in the dewar, or with a small low pressure pump. | 08-05-2010 |
| 20110082454 | Cryosurgical System - A cryosurgical system using a low-pressure liquid nitrogen supply, which requires only 0.5 to 15 bar of pressure to provide adequate cooling power for treatment of typical breast lesions. The pressure may be provided by supplying lightly pressurized air into the dewar, by heating a small portion of the nitrogen in the dewar, or with a small low pressure pump. | 04-07-2011 |
| 20110112521 | Cryoprobe for Low Pressure Systems - A cryoprobe for use in cryosurgery and other applications comprising a rigid outer tube, an inner coolant inlet tube. a short rigid penetrating segment extending distally from the distal end of the outer tube and a helical-shaped baffle having a heating element disposed about the outer surface of the inlet tube. The baffle is adapted to produce turbulent fluid flow improving heat transfer and is able to warm target tissue during rapid freezing and thawing cycles. | 05-12-2011 |
David W. Foster, Bolton GB
| Patent application number | Description | Published |
|---|---|---|
| 20110099854 | ARTICLE OF FOOTWEAR - The present invention relates to an article of footwear ( | 05-05-2011 |
| 20110131841 | ARTICLE OF FOOTWEAR - The present invention relates to a control element ( | 06-09-2011 |
Duncan Foster, Woodbridge Suffolk GB
Elizabeth Foster, Newbury GB
| Patent application number | Description | Published |
|---|---|---|
| 20110145202 | Archiving system - An archiving system for enabling searching for collections of items is disclosed. A processing unit displays an archived items collection management template in respect of a particular collection of items and prompts a user to complete the template fields with data obtained by the user from manually reviewing that collection of items to capture information relevant to each of the template fields. An archiving controller stores, in pre-determined data fields of a storage area of a data store corresponding to said collection of items, the data from the completed template fields. A document search controller may search the pre-determined data fields of the storage areas of the data store corresponding to each of the collections of items to identify ones of the collection of items which match search criteria. | 06-16-2011 |
Gareth Foster, Shoreham-By-Sea/west Sussex GB
| Patent application number | Description | Published |
|---|---|---|
| 20100172648 | Installation for Conveying a First Plurality of Electrical Signals Carried by a First Triaxial Cable to a Second Triaxial Cable - The present invention relates to an installation for conveying electrical signals carried by a first triaxial cable ( | 07-08-2010 |
Gerald T. Foster, Marston Meysey GB
| Patent application number | Description | Published |
|---|---|---|
| 20100093351 | CODE DIVISION MULTIPLE ACCESS CELLULAR COMMUNICATION SYSTEM - A base station ( | 04-15-2010 |
Gerard T. Foster, Marston Meysey GB
| Patent application number | Description | Published |
|---|---|---|
| 20090318144 | CELLULAR COMMUNICATION SYSTEM AND METHOD OF OPERATION THEREFOR - A cellular communication system comprises a first base station ( | 12-24-2009 |
| 20100120437 | CELLULAR COMMUNICATION SYSTEM AND METHOD OF OPERATION THEREFOR - A cellular communication system comprises an access point ( | 05-13-2010 |
| 20110105133 | RESTRICTED ACCESS IN CELLULAR COMMUNICATION SYSTEMS - A cellular communication system comprises a base station which can to operate in a restricted mode wherein support is restricted to user equipments of a first associated set of user equipments, such as a Closed Subscriber Group. The base station comprises a profile unit which determines a first transmit power profile where the first transmit power profile is indicative of the base station operating in the restricted mode. The base station further comprises a transmitter for transmitting at least one common channel, such as a pilot signal or a broadcast signal, with a transmit power according to the first transmit power profile. User Equipments may measure the power profile to evaluate whether the base station employs restricted access. The invention may in particular reduce the number of access attempts to restricted base stations by non-eligible User Equipments. | 05-05-2011 |
Gerard T. Foster, Swindon GB
| Patent application number | Description | Published |
|---|---|---|
| 20090003263 | NETWORK FOR A CELLULAR COMMUNICATION SYSTEM AND A METHOD OF OPERATION THEREFOR - A network for a cellular communication system comprises access points ( | 01-01-2009 |
| 20090104912 | OPTIMIZING POWER SETTINGS IN A COMMUNICATION SYSTEM TO MITGATE INTERFERENCE - A method and apparatus for optimizing power settings in a communication system includes a first step ( | 04-23-2009 |
Gerard Terence Foster, Wiltshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20120039191 | ANALYSING RADIO NETWORK COVERAGE - A radio network coverage area provided by a mobile radio network is analysed. The analysis is provided by receiving control messages from a first interface communicated between a base station of the mobile radio network and a radio network controller, the control messages being provided for controlling the communications of the data to or from the mobile terminals via the base station. The method includes identifying a mobile identity number associated with the mobile terminal from the control messages communicated via the first interface, identifying, using the mobile identity number, mobility control messages communicated via the first interface, the mobility control messages providing an indication of a relative distance of the mobile terminal from the base station, receiving data communicated via a second interface between the radio network controller and a core network part of the mobile radio network, identifying the data communicated from the mobile terminal, using the mobile identity number identified from the first interface, determining a relative measure of quality of the data received from the mobile terminal, and generating a performance map providing a relative distance of the mobile terminal from the base station and a quality of data communicated at the relative distance from the mobile terminal. | 02-16-2012 |
| 20120072200 | MODELLING APPARATUS AND METHOD - A method of processing a model of a telecommunications network, the telecommunications network. The method includes dividing the network elements of the telecommunications network into a plurality of different groups, for a first of the group of network elements being modelled, loading computer program code representing the group of network elements being modelled into the computer memory and executing the computer program to model the first group of network elements within a first time period. For a subsequent time period the first group of network elements is represented by the amount of network services consumed on the one or more interfaces with the second group of network elements determined within the first time period, whilst loading into the computer memory computer program code to model the second group of network elements. In this way, an improvement in modelling telecommunications networks is provided by dividing each of the component parts of the telecommunications network into groups, and handling these groups on a cyclic basic. | 03-22-2012 |
| 20120093029 | MODELLING APPARATUS AND METHOD - A method of processing a model of a telecommunications system including a plurality of access nodes through which communications terminals can communicate data is described. The method includes dividing the communications terminals, the access nodes and the core network into different groups, for a first of the groups loading the computer program code representing the communications terminals, the access nodes or the core network of the first group into the computer memory and performing the representing with the processor within a first time period, determining an amount of the data communicated between the first group and one or more of the other groups during the first time period, and for a subsequent time period representing the first group by an amount of data corresponding to the amount of the data communicated between the first group and a second of the groups, whilst loading the computer program code into the computer memory and performing the representing of the second group within the subsequent time period. The results produced by the modeling can be used to configure the telecommunications system itself. | 04-19-2012 |
| 20120113821 | MODELLING APPARATUS AND METHOD - A method determined a routing of data between two network elements of a telecommunications network, which are interconnected via a transmission path. The method includes identifying plurality of layers of a telecommunications model from which the transmission path is comprised, and developing a reachability table by identifying a connection between each transmission element in each layer to other transmission elements in the same or a different layer of the transmission path. For each connection defining a set of communications parameters which define a cost of communicating data via the connection and allocating a weighting value for communicating data via the connection, for all possible routes between the two network elements along the transmission path via each of the layers modelling the effect of the connection for routing the data in accordance with the set of communications parameters for the connection and determining a weighted result along each path, and combining the weighted results to determine a metric of performance for each of the possible routes. An optimum route can then be determined for routing data in accordance with for example a minimum cost metric. | 05-10-2012 |
Graham Foster, Swansea GB
| Patent application number | Description | Published |
|---|---|---|
| 20100174131 | Reduced Diameter Axial Rotary Pump for Cardiac Assist - The pump is of an axial flow rotary type suitable for implantation into the human heart or vascular system. The pump has an elongate tubular casing ( | 07-08-2010 |
| 20110113771 | Wave Powered Generator - The generator comprises a float ( | 05-19-2011 |
| 20110124950 | Heart Assist Apparatus - The apparatus for implantation into a human heart comprises a pump ( | 05-26-2011 |
| 20110144413 | Heart Assist Apparatus - The apparatus is a ventricular assist device comprising: a pump with a housing having therein radial a impeller, and a rotor for driving the impeller, both the rotor and the impeller being hydrodynamically suspended within the housing in us, the pump further including a stator for driving the rotor; an inlet cannula section arranged to extend from an internal part of the ventricle to straddle the wall of the ventricle, the stator being within the inlet cannula section to be located in the internal part of the ventricle; and an outlet for blood driven by the impeller such that the pump is a radial pump. Both the outlet and the impeller are arranged to reside outside of the heart. | 06-16-2011 |
| 20120088954 | Cardiac Pump - The pump is of an axial flow rotary pump, suitable for implantation into the human heart or vascular system, and comprises an elongate tubular casing ( | 04-12-2012 |
Ian Foster, Reading GB
| Patent application number | Description | Published |
|---|---|---|
| 20100101345 | GEARBOX - A mainshaft assembly for a gearbox and a gearbox embodying such a mainshaft assembly are disclosed. The mainshaft assembly comprises a mainshaft ( | 04-29-2010 |
John Foster, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20100203968 | Apparatus And Method Of Avatar Customisation - An entertainment device comprises skeletal modelling means to control placements of a three dimensional mesh representing some or all of a user avatar in response to the position of one or more skeletal components of the user avatar, skeleton modification means to modify one or more physical properties of one or more skeletal components of the user avatar via a user interface, and rendering means to render the user avatar responsive to the modified user avatar skeleton. | 08-12-2010 |
John Foster, Winchester GB
| Patent application number | Description | Published |
|---|---|---|
| 20110300059 | PROCESS FOR GAS SWEETENING - A process for treating a gas stream comprising hydrogen sulphide, the process comprising the steps of: (i) mixing a first gas stream comprising hydrogen sulphide with a second stream comprising sulphur dioxide to produce a combined stream, whereby elemental sulphur is produced by a reaction between the hydrogen sulphide and the sulphur dioxide; (ii) removing elemental sulphur, and optionally water, from the combined stream; and (iii) oxidising at least some of the elemental sulphur to form sulphur dioxide for use in the second stream, wherein, the reaction is conducted at a temperature of from 15 to 155° C. and a pressure of at least 3 MPa. | 12-08-2011 |
Jonathan C. Foster, Bradford-On-Avon GB
Keith Foster, Abingdon GB
| Patent application number | Description | Published |
|---|---|---|
| 20110027256 | FUSION PROTEINS - A single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a dynorphin Targeting Moiety that is capable of binding to a Binding Site on the nociceptive sensory afferent, which Binding Site is capable of undergoing endocytosis to be incorporated into an endosome within the nociceptive sensory afferent; a protease cleavage site at which site the fusion protein is cleavable by a protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the dynorphin Targeting Moiety; and a translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the nociceptive sensory afferent. Nucleic acid sequences encoding the polypeptide fusion proteins, methods of preparing same and uses thereof are also described. | 02-03-2011 |
| 20110158973 | SUPPRESSION OF CANCERS - The present invention relates to a method for suppressing or treating cancer, in particular to a method for suppressing or treating one or more of colorectal cancer, breast cancer, prostate cancer and/or lung cancer. The therapy employs use of a non-cytotoxic protease, which is targeted to a growth hormone-secreting cell such as to a pituitary cell. When so delivered, the protease is internalised and inhibits secretion/transmission of growth hormone from said cell. The present invention also relates to polypeptides and nucleic acids for use in said methods. | 06-30-2011 |
| 20110160135 | SUPPRESSION OF NEUROENDOCRINE DISEASES - The present invention relates to a method for suppressing neuroendocrine disease. The therapy employs use of a non-cytotoxic protease, which is targeted to a neuroendocrine tumour cell, preferably via a somatostatin or cortistatin receptor, a GHRH receptor, a ghrelin receptor, a bombesin receptor, a urotensin receptor a melanin-concentrating hormone receptor 1; a KiSS-1 receptor or a prolactin-releasing peptide receptor. When so delivered, the protease is internalised and inhibits secretion from said tumour cell. The present invention also relates to polypeptides and nucleic acids for use in said methods. | 06-30-2011 |
| 20120058098 | NON-CYTOTOXIC PROTEIN CONJUGATES - The present invention is directed to non-cytotoxic protein conjugates for inhibition or reduction of exocytic fusion in a nociceptive sensory afferent cell. The protein conjugates comprise: (i) a dynorphin Targeting Moiety (TM), wherein the TM is an agonist of a receptor present on a nociceptive sensory afferent cell, and wherein the receptor undergoes endocytosis to be incorporated into an endosome within the nociceptive sensory afferent cell; (ii) a non-cytotoxic protease or a fragment thereof, wherein the protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of the nociceptive sensory afferent cell; and (iii) a Translocation Domain, wherein the Translocation Domain translocates the protease or protease fragment from within the endosome, across the endosomal membrane, and into the cytosol of the nociceptive sensory afferent cell. Nucleic acid sequences encoding the protein conjugates, methods of preparing same and uses thereof are also described. | 03-08-2012 |
| 20120064059 | FUSION PROTEINS - A single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a Targeting Moiety that is capable of binding to a Binding Site on the nociceptive sensory afferent, which Binding Site is capable of undergoing endocytosis to be incorporated into an endosome within the nociceptive sensory afferent; a protease cleavage site at which site the fusion protein is cleavable by a protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the Targeting Moiety; a translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the nociceptive sensory afferent. Nucleic acids encoding the fusion proteins, methods of preparing same and uses thereof are also described. | 03-15-2012 |
Keith Foster, Wiltshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090162341 | Non-Cytotoxic Protein Conjugates - A non-cytotoxic protein conjugate for inhibition or reduction of exocytic fusion in a nociceptive sensory afferent cell, comprising: (i) a Targeting Moiety (TM), wherein said TM is an agonist of a receptor present on said nociceptive sensory afferent cell, and wherein said receptor undergoes endocytosis to be incorporated into an endosome within the nociceptive sensory afferent cell; (ii) a non-cytotoxic protease or a fragment thereof, wherein the protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of said nociceptive sensory afferent cell; and (iii) a Translocation Domain, wherein the Translocation Domain translocates the protease or protease fragment from within the endosome, across the endosomal membrane, and into the cytosol of the nociceptive sensory afferent cell. Nucleic acid sequences encoding the protein conjugates, methods of preparing same and uses thereof are also described. | 06-25-2009 |
| 20100247509 | Fusion Proteins - A single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a Targeting Moiety that is capable of binding to a Binding Site on the nociceptive sensory afferent, which Binding Site is capable of undergoing endocytosis to be incorporated into an endosome within the nociceptive sensory afferent; a protease cleavage site at which site the fusion protein is cleavable by a protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the Targeting Moiety; and a translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the nociceptive sensory afferent. Nucleic acid sequences encoding the polypeptide fusion proteins, methods of preparing same and uses thereof are also described. | 09-30-2010 |
Keith Foster, Salisbury GB
| Patent application number | Description | Published |
|---|---|---|
| 20090035822 | Fusion Proteins - A single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a Targeting Moiety that is capable of binding to a Binding Site on the nociceptive sensory afferent, which Binding Site is capable of undergoing endocytosis to be incorporated into an endosome within the nociceptive sensory afferent; a protease cleavage site at which site the fusion protein is cleavable by a protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the Targeting Moiety; and a translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the nociceptive sensory afferent. Nucleic acid sequences encoding the polypeptide fusion proteins, methods of preparing same and uses thereof are also described. | 02-05-2009 |
| 20090291457 | RE-TARGETED TOXIN CONJUGATES - The present invention provides a method for designing a re-targeted toxin conjugate for use in treating a medical condition or disease. Also provided, is the use of said conjugates in the manufacture of a medicament for treating medical conditions or diseases. The conjugates include a Targeting Moiety, which directs the conjugate to a desired target cell, and are characterised by a Targeting Moiety that increases exocytic fusion in the target cell. The present invention also provides methods for identifying agonists suitable for use as Targeting Moieties, and methods for preparing conjugates comprising said Targeting Moieties. | 11-26-2009 |
| 20100034802 | TREATMENT OF PAIN - Use of a therapeutic molecule, for the treatment of specific pain conditions, wherein the therapeutic molecule is a single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a Targeting Moiety that is capable of binding to a Binding Site on the nociceptive sensory afferent, which Binding Site is capable of undergoing endocytosis to be incorporated into an endosome within the nociceptive sensory afferent; a protease cleavage site at which site the fusion protein is cleavable by a protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the Targeting Moiety; and a translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the nociceptive sensory afferent. | 02-11-2010 |
| 20110091437 | FUSION PROTEINS - A single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a dynorphin Targeting Moiety that is capable of binding to a Binding Site on the nociceptive sensory afferent, which Binding Site is capable of undergoing endocytosis to be incorporated into an endosome within the nociceptive sensory afferent; a protease cleavage site at which site the fusion protein is cleavable by a protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the dynorphin Targeting Moiety; and a translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the nociceptive sensory afferent. Nucleic acid sequences encoding the polypeptide fusion proteins, methods of preparing same and uses thereof are also described. | 04-21-2011 |
| 20110177053 | NON-CYTOTOXIC PROTEIN CONJUGATES - The present invention is directed to non-cytotoxic protein conjugates for inhibition or reduction of exocytic fusion in a nociceptive sensory afferent cell. The protein conjugates comprise: (i) a Targeting Moiety (TM), wherein the TM is an agonist of a receptor present on a nociceptive sensory afferent cell, and wherein the receptor undergoes endocytosis to be incorporated into an endosome within the nociceptive sensory afferent cell; (ii) a non-cytotoxic protease or a fragment thereof, wherein the protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of the nociceptive sensory afferent cell; and (iii) a Translocation Domain, wherein the Translocation Domain translocates the protease or protease fragment from within the endosome, across the endosomal membrane, and into the cytosol of the nociceptive sensory afferent cell. Nucleic acid sequences encoding the protein conjugates, methods of preparing same and uses thereof are also described. | 07-21-2011 |
Keith Foster, Oxfordshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20110171191 | SUPPRESSION OF NEUROENDOCRINE DISEASES - The present invention relates to a method for suppressing neuroendocrine disease. The therapy employs use of a non-cytotoxic protease, which is targeted to a neuroendocrine tumour cell, preferably via a somatostatin or cortistatin receptor, a GHRH receptor, a ghrelin receptor, a bombesin receptor, a urotensin receptora melanin-concentrating hormone receptor 1; a KiSS-1 receptor or a prolactin-releasing peptide receptor. When so delivered, the protease is internalised and inhibits secretion—from said tumourcell. The present invention also relates to polypeptides and nucleic acids for use in said methods. | 07-14-2011 |
| 20110262423 | SUPPRESSION OF CANCER - The present invention relates to polypeptides for use in suppressing cancer and cancer disorders. The treatment employs use of a non-cytotoxic protease, which is targeted to the cancer cell, and, when so delivered, the protease is internalised and inhibits secretion from the cancer cell. | 10-27-2011 |
Keith Foster, Oxon GB
| Patent application number | Description | Published |
|---|---|---|
| 20110165137 | SUPPRESSION OF CANCERS - The present invention relates to a method for suppressing or treating cancer, in particular to a method for suppressing or treating one or more of colorectal cancer, breast cancer, prostate cancer and/or lung cancer. The therapy employs use of a non-cytotoxic protease, which is targeted to a growth hormone-secreting cell such as to a pituitary cell. When so delivered, the protease is internalised and inhibits secretion/transmission of growth hormone from said cell. The present invention also relates to polypeptides and nucleic acids for use in said methods. | 07-07-2011 |
Kevin Anthony Foster, Kent GB
| Patent application number | Description | Published |
|---|---|---|
| 20110198239 | SIMULTANEOUS DETERMINATION OF CHLORINE AND CHLORATE IN SODIUM HYPOCHLORITE - A process for the simultaneous determination of chlorine and chlorate in sodium hypochlorite. First and second streams of sodium hypochlorite are provided. The first stream is treated to generate iodine indicative of chlorine. The second stream is treated to generate iodine indicative of chlorine and chlorate. The iodine of the first stream is subjected to an amperometric measuring cell to generate a first current proportional to a chlorine concentration of the first stream. The iodine of the second stream is subjected to an amperometric measuring cell to generate a second current proportional to the chlorine and chlorate concentration in the second stream. The first current is subtracted from the second current to determine an amount of chlorate. | 08-18-2011 |
Kevin Anthony Foster, Aylesford GB
| Patent application number | Description | Published |
|---|---|---|
| 20110264268 | Electrochemical Control Systems And Methods - Methods for reducing response time of membrane based electrochemical cells. A probe correction factor is calculated based on a percent rate of change in probe signal with time. A staged correction may be applied such that as signal change gets smaller, the effect of the compensation is reduced to prevent over shoot on the calculated residual. Control systems and techniques can regulate or control operations of a water treatment system. | 10-27-2011 |
Kevin Anthony Foster, Aylesford Kent GB
| Patent application number | Description | Published |
|---|---|---|
| 20110040494 | METHOD AND APPARATUS FOR ABSORPTION SPECTRA ANALYSIS - A method and apparatus is disclosed for resolving absorption spectra such as ultraviolet or visible spectra having individual peaks attributable to more than one component in a sample mixture. The invention exploits the observation that the peak wavelength varies according to the component concentrations, providing the basis for an initial estimate of these. A curve fitting exercise is performed for a range of possible concentrations encompassing the initial estimates so that the a theoretical spectrum having the closest match to that observed provides for a refined estimate of component concentrations. | 02-17-2011 |
Lawrence D. Foster, Derby GB
| Patent application number | Description | Published |
|---|---|---|
| 20100158604 | Catcher pin assembly - A catcher pin assembly for attachment to a catcher link of an aircraft frame, the catcher pin assembly comprising an engine mounting element | 06-24-2010 |
| 20120096951 | CATCHER PIN ASSEMBLY - A catcher pin assembly for attachment to a catcher link of an aircraft frame, the catcher pin assembly having an engine mounting element, a catcher pin, a compressible element, and a nut, which is lockable to the catcher pin, the compressible element being compressed between the pin and the mounting element and/or between the mounting element and the nut, in the assembled condition of the assembly, such that the compressible element applies a predetermined resistance to rotation of the catcher pin relative to the mounting element. The invention also relates to a method of testing a catcher pin assembly to determine if the catcher pin is carrying load from the catcher link, the method including applying a predetermined torque to the catcher pin sufficient to overcome the resistance to rotation of the catcher pin when it is unloaded, and determining whether the catcher pin rotates relative to the mounting element. | 04-26-2012 |
Louise Caroline Foster, Castleford GB
| Patent application number | Description | Published |
|---|---|---|
| 20090051093 | CLAMP HEAD - The present invention provides clamp head comprising an arched body having upper and lower faces, a vertex and opposing unequal length arms. The body is further provided with a through aperture for a bolt or like threaded fastener which extends between the upper and lower faces in the region of the vertex. The aperture in the upper face is oval and tapers outwardly through the body in the direction of the lower face. The arms comprise a reaction arm having at its distal end a reaction face and a clamping arm having at its distal end a clamping face, the reaction and clamping faces being provided with respective formations. The formations of the reaction arm extend in a direction which is substantially transverse to the direction of the formations of the clamping arm. | 02-26-2009 |
Marcus Foster, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20120063577 | CALL STATUS SHARING - In general, techniques are described for sharing information about a client device phone call to enhance other services. In one example, a method includes receiving, at a server device, voice call parameters that describe at least one characteristic of a voice call in which a user of a first device is participating wherein the first device is physically separate from the server device, and responsive to receiving the voice call parameters, determining, by the server device, a status of the user based on the received voice call parameters. The method further includes storing an account for the user on the server device, wherein the account includes a user profile for the user and identifies contacts of the user, and modifying, by the server device, the user profile to reflect the status of the user, and sending the modified user profile to a device associated with a contact of the user. | 03-15-2012 |
| 20120064862 | CALL STATUS SHARING - In general, techniques are described for sharing information about a client device phone call to enhance other services. In one example, a method includes receiving, at a server device, voice call parameters that describe at least one characteristic of a voice call in which a user of a first device is participating wherein the first device is physically separate from the server device, and responsive to receiving the voice call parameters, determining, by the server device, a status of the user based on the received voice call parameters. The method further includes storing an account for the user on the server device, wherein the account includes a user profile for the user and identifies contacts of the user, and modifying, by the server device, the user profile to reflect the status of the user, and sending the modified user profile to a device associated with a contact of the user. | 03-15-2012 |
Mark Stuart Foster, Buckinghamshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20110079461 | SEISMIC SURVEY METHOD - A method of conducting a seismic survey comprising using at least one seismic source operable to emit an acoustic signal comprises: —providing a first receiver line extending in a first direction across a region of the ground to be surveyed; —locating at least one seismic receiver at a point on the first receiver line, the seismic i receiver(s) being adapted to record reflected acoustic signals emitted by the seismic source(s); —providing a first pre-determined shot line having a plurality of shot points along its length, extending in a second direction and along which the seismic source(s) is movable; —operating the or one of the seismic source(s) to emit an acoustic signal at a first shot point on the pre-determined shot line, the reflection of the acoustic signal being recorded by the or one of the seismic receiver(s); and —operating the or one of the seismic source(s) to emit another acoustic signal at a second shot point on the pre-determined shot line, the reflection of the another acoustic signal being recorded by the or one of the seismic receiver(s); characterised in that at least one of the first receiver line and the first pre-determined shot line passes through or at least partially along a generally horizontal borehole extending through the region of the ground to be surveyed and the first pre-determined shot line transects the first receiver line. | 04-07-2011 |
Mike Foster, Westhill GB
| Patent application number | Description | Published |
|---|---|---|
| 20110048742 | Downhole Safety Valve Having Flapper and Protected Opening Procedure - A downhole valve has a closure device (e.g., one or more flappers) for closing off the valve. A no-go actuation mechanism protects the flappers from damage. When the flappers are closed, the mechanism prevents a tool from passing into the valve and causing damage to the flappers. Yet, the mechanism may open the valve's flappers when the tool string is forced into the valve. When the valve has successfully opened, then the mechanism moves out of the way of the toolstring so it can pass through the valve. For the mechanically operated valves, operators use a shifting profile in the valve only in the upward direction to return the valve to the closed position. For hydraulic actuated valves, hydraulic pressure may be used or exhausted, depending on the design, to allow the flappers to go closed. Once the flappers have closed, the no-go mechanism is once again realized. | 03-03-2011 |
Neil Robert Foster, Aberdeenshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20100003169 | PHOTOCATALYTIC REACTOR - A photocatalytic reactor for carrying out a photocatalytic reaction on a liquid which is to be treated, the reactor comprising a reaction chamber which comprises: (i) a foraminated member which supports a plurality of mobile photocatalyst particles, the size and density of which is such that they tend to rest on the foraminated member in use; and (ii) an aeration device which causes gas bubbles to rise from the foraminated member and agitate the mobile photocatalyst particles. The reactor may be a flow-through reactor. The photocatalytic reactor can be applied to the remediation of waste water using titanium oxide. | 01-07-2010 |
Nicholas Foster, West Yorkshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20080251451 | Method and Apparatus for the Aerobic Treatment of Waste - The invention provides a waste treatment apparatus for the microbial treatment of waste, and comprises at least one reactor vessel ( | 10-16-2008 |
Paul Foster, Slough GB
| Patent application number | Description | Published |
|---|---|---|
| 20090182000 | STEROIDAL COMPOUNDS AS STEROID SULPHATASE INHIBITORS - There is provided a compound having Formula I | 07-16-2009 |
Paul Alexander Foster, Berkshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20100144652 | COMPOSITION COMPRISING A GLYCOLYTIC INHIBITOR AND A RING SYSTEM COMPRISING A SULPHAMATE GROUP FOR THE TREATMENT OF CANCER - The present invention provides a composition comprising (a) a glycolytic inhibitor (b) a compound comprising a ring system substituted with at least one of a suiphamate group and an alkoxy group; wherein (a) and (b) are different. | 06-10-2010 |
Paul Alexander Foster, Slough GB
| Patent application number | Description | Published |
|---|---|---|
| 20100105764 | USE - There is provided a method for the manufacture of a medicament for the treatment of cancer comprising a compound capable of inhibiting a steroid sulphatase enzyme (E.C.3.1.6.2), wherein the cancer is of a type, in which the cancer cells overexpress aromatase enzyme. | 04-29-2010 |
Paul W. Foster, Felixstowe GB
| Patent application number | Description | Published |
|---|---|---|
| 20100030725 | DATA TRIPLE USER ACCESS - A computerized data processing method for providing access to data triples ( | 02-04-2010 |
Peter F.w. Foster, Burton On Trent GB
| Patent application number | Description | Published |
|---|---|---|
| 20110126544 | AIR FLOW PASSAGE LINER - A liner is provided for an air flow passage of a gas turbine engine. The liner comprises an acoustic attenuation layer which forms an air-washed surface of the flow passage, and a heat exchanger layer which extends as a backing to the acoustic attenuation layer. The heat exchanger layer is configured to carry a heated fluid flow and to transport heat from the fluid flow to the acoustic attenuation layer from where the heat is transferred to air flowing through the air flow passage. | 06-02-2011 |
Richard Foster, Bude GB
| Patent application number | Description | Published |
|---|---|---|
| 20080318935 | SUBSTITUTED IMIDAZOHETEROCYCLES - The present invention provides substituted imidazoheterocyclic compounds having the structure of formula I | 12-25-2008 |
| 20090149450 | SUBSTITUTED IMIDAZOHETEROCYCLES - The present invention provides substituted imidazoheterocyclic compounds having the structure of formula I | 06-11-2009 |
| 20110034443 | USES OF SUBSTITUTED IMIDAZOHETEROCYCLES - The present invention provides methods of prevention and treatment of cannabinoid receptor-associated diseases and conditions, wherein the method includes administering a substituted imidazoheterocyclic compounds having the structure of formula I or a pharmaceutically acceptable salt, acid salt, hydrate, solvate or stereoisomer of a compound having the structure of formula I. | 02-10-2011 |
Richard Foster, Fordingbridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20090022363 | WATERMARKING AND TRANSFERRING MATERIAL - A client device for use in a system having a server, the client device including: a receiving device configured to receive information material from the server, the information material containing a reversible modification providing a perceptible disturbing effect to the information material, and to receive identifying information that distinguishes the information material from other information material available from the server and condition information which defines a predetermined condition that should be met in order for the reversible modification to be reversed; a transmission device which, in response to a user input providing enabling data which satisfies the predetermined condition, configured to transmit the identifying information and the enabling data to the server, wherein in response to the transmission of the enabling data and the identifying information, the receiving device is configured to receive a key and removing data defining an algorithm for removing the perceptible effect, the removing data being useable by a reversing device to reverse the perceptible effect; and a storage device configured to store the information material that has had the perceptible effect reversed. | 01-22-2009 |
Richard Daniel Foster, Fordingbridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20090028528 | AUDIO AND/OR VIDEO GENERATION APPARATUS AND METHOD OF GENERATING AUDIO AND/OR VIDEO SIGNALS - A camera configured to generate audio/video signals, the camera including a recording unit configured to record the audio/video signals on a recording medium, a meta data generation processor configured to generate automatically meta data identifying the content of the audio/video signals in response to the audio/video signals, a wireless communications processor configured to communicate the meta data separately from the recording medium, and a communications interface configured to communicate the automatically generated meta data to a personal data processing apparatus and to receive user generated meta data from the personal data processing apparatus. | 01-29-2009 |
Richard Graham Foster, Haslemere GB
| Patent application number | Description | Published |
|---|---|---|
| 20100287086 | Asset and liability modeling tool - A method for modeling financial variables describing a client over a time period. The method may comprise the step of generating a first simulation of the time period. Generating the first simulation may comprise the steps of assigning the client to a first health-related state and advancing the first simulation from a first interval of the time period to a second interval of the time period. A probability that the client will transition from the first health-related state to a second health-related state may be calculated, the client may be randomly assigned to either the first health-related state or the second health-related state considering the probability. According to various embodiments, the methods may also comprise the steps of calculating a client income for the second interval; and calculating a plurality of client expenses for the second interval. Also, the various health-related states may include one or more of a healthy state, a long term care (LTC) state, a disabled state and a dead state. | 11-11-2010 |
Simon Foster, Hathersage GB
| Patent application number | Description | Published |
|---|---|---|
| 20090269349 | ANTIGENIC POLYPEPTIDES - The invention relates to a method for the identification of antigenic polypeptides, typically opsonic antigens, expressed by pathogenic microbes; vaccines comprising said antigens; and therapeutic antibodies directed to said antigenic polypeptides. | 10-29-2009 |
| 20100166792 | Antigenic Polypeptides - The invention relates to a method for the identification of antigenic polypeptides expressed by pathogenic microbes; vaccines comprising said polypeptides; recombinant methods to manufacture said polypeptides; and therapeutic antibodies directed to said polypeptides. | 07-01-2010 |
Simon E. Foster, Leicestershire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090029231 | VARIABLE COMPRESSIBILITY GASKETS - A gasket formed of compressible material and having a first sealing surface and a second sealing surface for providing a fluid seal between a first component and a second component, a plurality of cavities provided within the gasket proximate the first and/or second sealing surfaces and extending over at least a first portion of the gasket to provide increased compressibility of the gasket in the first portion. | 01-29-2009 |
Simon Edward Foster, Leicestershire GB
| Patent application number | Description | Published |
|---|---|---|
| 20080248336 | Water Management in Fuel Cells - An electrochemical fuel cell having an anode, an ion transfer membrane and a cathode has liquid water delivered to the fluid flow channels within the cathode so as to maintain a relative humidity of 100% throughout the fluid flow channels. A calibration method and apparatus is described for determining an optimum quantity or range of quantities of liquid water to be delivered to the cathode fluid flow channels under varying operating conditions. An operating method and apparatus is described that ensures an optimum quantity of liquid water is delivered to the cathode fluid flow channels under varying operating conditions. | 10-09-2008 |
| 20090311569 | GASKETS FOR FUEL CELLS - A gasket for sealing internal surfaces of a fuel cell and formed of compressible material, the gasket comprising a first sealing surface and a second sealing surface for providing a fluid seal against opposing faces of a first fluid flow field plate and a second fluid flow field plate respectively, the gasket further comprising a third sealing surface for sealing against an outer perimeter region of a first surface of a membrane electrode assembly, the third sealing surface being entirely enclosed within a boundary defined by an inner perimeter of the second sealing surface. | 12-17-2009 |
Simon J. Foster, Sheffield GB
| Patent application number | Description | Published |
|---|---|---|
| 20110171237 | PHEP, AN AMINO ACID PERMEASE OF STAPHYLOCOCCUS AUREUS - The present invention relates to antigenic polypeptides expressed by pathogenic microbes, including antigenic polypeptides encoded by the nucleic acid sequence of FIG. | 07-14-2011 |
Simon J. Foster, Hathersage GB
| Patent application number | Description | Published |
|---|---|---|
| 20080311108 | Polypeptides - The invention relates to antigenic polypeptides expressed by pathogenic microbes, vaccines comprising said polypeptides; therapeutic antibodies directed to said polypeptides and methods to manufacture said polypeptides, vaccines and antibodies. | 12-18-2008 |
| 20110091465 | POLYPEPTIDES - The invention relates to antigenic polypeptides expressed by pathogenic microbes, vaccines comprising said polypeptides; therapeutic antibodies directed to said polypeptides and methods to manufacture said polypeptides, vaccines and antibodies. | 04-21-2011 |
Simon John Foster, Norfolk GB
| Patent application number | Description | Published |
|---|---|---|
| 20100192257 | LATE BLIGHT RESISTANCE GENES AND METHODS - This invention provides novel gene sequences, compositions and methods for enhancing the resistance in crops, in particular but not limited to, potato, to late blight caused by the oomycete pathogen | 07-29-2010 |
Stephen Foster, Macclesfield Cheshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090190125 | Device and Method for Spectrometric System - The invention relates to a device for use in analysing the performance of a spectrometric system of the type which comprises a spectrometer to which a probe for propagating electromagnetic radiation is connected. The device comprises a holder for holding both a reflectance standard and the probe so that the tip of the probe is fixated at a predetermined position relative to the reflectance standard and so that at least part of the electromagnetic radiation emitted from the probe is diffusely reflected from the reflectance standard back to the probe. The invention also relates to a method, a kit and an assembly. | 07-30-2009 |
Stephen Leslie Foster, Blackburn GB
| Patent application number | Description | Published |
|---|---|---|
| 20090308570 | RADIATOR - A radiator, particularly a skirting radiator for heating a room space is mounted just above level. An elongate panel ( | 12-17-2009 |
Timothy John Foster, Nottingham GB
| Patent application number | Description | Published |
|---|---|---|
| 20120115964 | XANTHAN GUM AND SWELLABLE PARTICULATE CONTAINING COMPOSITION AND USES THEREOF - This invention relates to a composition comprising at least about 0.2% w/w xanthan gum and at least about 6% w/w of a swellable particulate, and to uses thereof. | 05-10-2012 |
Winston Foster, Middlesex GB
| Patent application number | Description | Published |
|---|---|---|
| 20090022859 | Container assembly - The invention relates to a container assembly comprising fluid, and particularly beverage, cooling and/or mixing means. The cooling and/or mixing is achieved by positioning a movable plunger assembly within the container, the base of which defines notional volume variable upper and lower chambers of the container. The base of the plunger is provided with perforations (and optionally, sealable compartments for sugar, milk etc.) adapted to allow pressurised liquid to be urged from the lower chamber to form upwardly directed jets of liquid in the upper chamber. The invention is particularly advantageous because it allows the consumer to selectively cool and/or mix a beverage by means of a plunging and/or twisting action, thus balancing the demand for hot beverages with the dangers of scalding. | 01-22-2009 |