Fontayne
Alexandre Fontayne, La Madeleine FR
Patent application number | Description | Published |
---|---|---|
20120258100 | CHIMERIC ANTI-RICIN ANTIBODY - A chimeric monoclonal antibody targeted at ricin, in which the light chain and heavy chain are such that: | 10-11-2012 |
20130122546 | NOVEL SIGNAL PEPTIDE, AND USE THEREOF FOR PRODUCING RECOMBINANT PROTEINS - A use of a signal peptide for producing a recombinant polypeptide of interest in an expression system, the signal peptide includes at least 12 amino acids of formula (I): | 05-16-2013 |
20140050722 | CHIMERIC ANTI-RICIN ANTIBODY - A chimeric monoclonal antibody targeted to ricin is presented. The light chain and heavy chain constant regions are respectively made up of the light chain and heavy chain constant regions of human immunoglobulin, and the light chain and heavy chain variable regions respectively include the light chain and heavy chain variable regions of macaque immunoglobulin. The antibody does not substantially induce any immune response against chimeric antibodies. | 02-20-2014 |
20140242638 | TRANSCRIPTION UNIT AND USE THEREOF IN (YB2/0) EXPRESSION VECTORS - A transcription unit constituted by a polynucleotide including the hCMVie virus enhancer, the enhancer having the nucleotide sequence SEQ ID NO: 1, or a nucleotide acid having at least 70% sequence identity with the sequence SEQ ID NO: 1 and essentially having transcription activation properties, and the promoter region of Cyclin-Dependent Kinase 9 (CDK9), the promoter region having the nucleotide sequence SEQ ID NO: 2, or a nucleotide acid having at least 70% sequence identity with the sequence SEQ ID NO: 2 and essentially having a promoter activity. | 08-28-2014 |
20140378663 | FC VARIANTS WITH REDUCED EFFECTOR FUNCTIONS - A method for producing a variant of a parent polypeptide including a Fc region, which variant exhibits reduced binding to the protein C1q and to at least one receptor Fcgγ R as compared to the parent polypeptide. | 12-25-2014 |
20150072368 | TRANSCRIPTION UNITS AND THE USE THEREOF IN EXPRESSION VECTORS - Novel transcription units that may be used in expression vectors. The transcription unit allow antibodies to be produced whose gain in productivity is not linked to a particular antigenic target antibody and therefore by extrapolation to a given recombinant protein, nor linked to the culture medium. | 03-12-2015 |
Diego Y. Fontayne, Monroe, NY US
Patent application number | Description | Published |
---|---|---|
20100224668 | Surgical Stapling System - A system is provided for joining two tubular structures by a surgical stapling procedure. The system includes a series of sizers, a specifically designed graft, a loading unit, a wand, a tourniquet, and a stapling instrument. The sizers are for determining the diameter of a target aorta and the availability of a sufficient transected aortic length to perform a stapling procedure. The loading unit holds the graft in position in the body and deploys a circumferential line of staples through the graft and an overlapping end of the aorta. The graft includes a side port by which the loading unit holds the graft during the stapling procedure, and which may be closed once the stapling procedure has been completed. The wand may be used to introduce the loading unit and graft into the body, to position them within the transected aorta, and to hold them in place during the application of the tourniquet. The tourniquet includes a band formed from a flexible material and having a width greater than its thickness so as to facilitate the formation of an annular loop. With the tourniquet holding the aorta and graft in relative overlapping positions, the wand may be removed from the loading unit and the stapling instrument includes a plurality of anvils, which may be closed to form a circle overlying the aorta, and a trigger mechanism for firing the staples. When fired, the staples are deployed radially outward through the graft and aorta, whereupon their free ends are bent inwardly by staple returns on the anvils. As a result, a plurality of staples may be simultaneously deployed quickly and accurately in a circumferential pattern so as to join together two tubular structures. The system may be used in either an open surgical procedure or laparascopically. | 09-09-2010 |
20130087596 | Surgical Stapling System - A system is provided for joining two tubular structures by a surgical stapling procedure. The system includes a series of sizers, a specifically designed graft, a loading unit, a wand, a tourniquet, and a stapling instrument. As a result, a plurality of staples may be simultaneously deployed quickly and accurately in a circumferential pattern so as to join together two tubular structures. The system may be used in either an open surgical procedure or laparascopically. | 04-11-2013 |