Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Folkman, US
Cache Folkman, Bettendorf, IA US
| Patent application number | Description | Published |
|---|---|---|
| 20090101245 | Method for Surface Cooling Steel Slabs to Prevent Surface Cracking, and Steel Slabs Made by That Method - A method is provided for the continuous casting, cutting, and continued heat treatment of steel slabs, particularly those having cracking-prone alloy formulations, without requiring the use of water spray quench cooling equipment. | 04-23-2009 |
Judah Folkman, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080248030 | Method of Treating Angiogenic Diseases - The present invention relates to methods for treating cancer comprising administering an anti-VEGF (vascular endothelial growth factor) monoclonal antibody (e.g. Avastin) and a N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-TNP-470 conjugate (e.g. Caplostatin) to a patient in need thereof. | 10-09-2008 |
| 20090176874 | TNP-470 POLYMER CONJUGATES AND USE THEREOF - The present invention relates to conjugates of water-soluble polymers and o-(chloracetyl-carbamoyl) fumagillol (TNP-470) and use of those conjugates as specific intracellular carriers of the TNP-470 into tumor vessels. The present invention further relates to use of those conjugates to lower the neurotoxicity of TNP-470. Preferably, the polymer has a molecular weight in the range of 100 Da to 800 kDa. More preferably, the polymer has a molecular weight no greater than 60 kDa. Most preferably, the polymer has a molecular weight in the range of 15 kDa to 40 kDa. | 07-09-2009 |
| 20090209497 | METHOD OF TREATING LYMPHANGIOLEIOMYOMATOSIS (LAM) - The invention provides a method for the treatment of Lymphangioleiomyomatosis (LAM) in the human subject in need thereof. The method comprises administering to the subject an effective amount of doxycycline or a salt thereof. The invention further provides a method for monitoring the efficacy of treatment. Treatment efficacy is monitored by measuring MMP levels. Reduction in MMP levels indicates that the treatment is effective. | 08-20-2009 |
| 20090280190 | ANTI-ANGIOGENIC PEPTIDES FROM THE N-TERMINUS OF ENDOSTATIN - Provided herein are anti-angiogenic comprising the N-terminal end of endostatin, nucleic acids encoding the same, pharmaceutical preparations comprising an effective amount of the peptide and nucleic acids and use of the pharmaceuticals in treating or preventing diseases or conditions associated with undesirable angiogenesis. | 11-12-2009 |
Judah M. Folkman, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090042229 | PLATELET BIOMARKERS FOR CANCER - The present invention relates to the fields of immunology and biochemistry. Particularly, the present invention describes methods, devices and kits for early detection of clinical conditions having associated changes in systemic angiogenic activity, particularly cancers, inflammatory conditions, infections, and events associated with pregnancy and abortion. | 02-12-2009 |
Mark Alan Folkman, Redondo Beach, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080225288 | Imaging Systems and Methods - Imaging systems and methods are provided. In one embodiment, an image system is disclosed that comprises a Raman gain medium configured to receive an image from a target area and a tunable laser configured to pump light into the Raman gain medium over a plurality of first wavelengths to induce amplification of the image over a plurality of second wavelengths strokes shifted from the plurality of first wavelengths. The image system further comprises an image detector system that receives and processes the amplified image over the plurality of second wavelengths. | 09-18-2008 |
Mark L. Folkman, Twin Falls, ID US
| Patent application number | Description | Published |
|---|---|---|
| 20100239718 | Use of polydimethylsiloxane and/or siloxane (silicone) derived chemical compounds in the suppression of mold and spoilage on harvested forages - The invention outlines the use of polydimethylsiloxane (PDMS) copolymer and/or a siloxane derived chemical compounds in the suppression of mold, heating and spoilage in animal feedstuffs and forage products. The PDMS compound and derivatives thereof are also found to suppress the damage resulting from oxidation within the feedstuff mass. When applied, PDMS coats the feedstuff and is included in the moisture portion of the feed or forage mass. This helps preserve the feed quality and slows the damaging effects of spoilage organisms and oxidation. | 09-23-2010 |
| 20110135788 | POLYSILOXANE (SILICONE) TREATMENT COMPOSITION FOR SUPPRESSION OF MOLD AND SPOILAGE ON ANIMAL FEED AND FORAGE, AND METHODS OF USING SAME - Polydimethylsiloxane and/or siloxane (silicone)-derived chemical compounds are used to coating harvested forages to protect against rain and/or other weather damage and to suppress mold and spoilage in harvested forages. The PDMS compound and derivatives thereof are also found to suppress the damage resulting from oxidation within the feedstuff mass. When applied, PDMS coats the feedstuff and is included in the moisture portion of the feed or forage mass. This helps preserve the feed quality and slows the damaging effects of spoilage organisms and oxidation. | 06-09-2011 |
M. Judah Folkman, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090075369 | Angiostatin Fragments and Method of Use - Fragments of an endothelial cell proliferation inhibitor and method of use therefor are provided. The endothelial proliferation inhibitor is a protein derived from plasminogen, or more specifically is an angiostatin fragment. The angiostatin fragments generally correspond to kringle structures occurring within the endothelial cell proliferation inhibitor. The endothelial cell inhibiting activity of these fragments provides a means for inhibiting angiogenesis of tumors and for treating angiogenic-mediated disease. | 03-19-2009 |
| 20090137518 | Therapeutic Antiangiogenic Endostatin Compositions - Endostatin compositions capable of inhibiting endothelial cell proliferation, inhibiting angiogenesis and causing tumor regression are described. Specifically, amino acid sequences of endostatin proteins and nucleic acid sequences coding for endostatin proteins are provided. | 05-28-2009 |