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Folkes
Adrian J. Folkes, Basel CH
| Patent application number | Description | Published |
|---|---|---|
| 20120035208 | PYRAZOLOPYRIDINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE - Compounds of Formula (I), and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including p110 alpha and other isoforms of PI3K, and for treating disorders such as cancer or inflammation mediated by lipid kinases. Methods of using compounds of Formula (I) for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. | 02-09-2012 |
Adrian J. Folkes, Slough GB
| Patent application number | Description | Published |
|---|---|---|
| 20080207609 | Pharmaceutical compounds - Fused pyrimidines of formula (I): | 08-28-2008 |
| 20080207611 | Pharmaceutical compounds - Fused pyrimidines of formula (I): | 08-28-2008 |
| 20090156601 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF CANCER - The invention provides compounds which are pyrimidines of formula (I): wherein —XR | 06-18-2009 |
| 20100234370 | PHARMACEUTICAL COMPOUNDS - Fused pyrimidines of formula (I): | 09-16-2010 |
| 20100280027 | PHARMACEUTICAL COMPOUNDS - Provided herein are methods of treating diseases or disorders arising from abnormal cell growth, function or behavior associated with PI3 kinase, which method includes administering to a patient in need thereof a compound that is a fused pyrimidine of formula (I): | 11-04-2010 |
Adrian J. Folkes, Berkshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090209559 | PHARMACEUTICAL COMPOUNDS - Fused pyrimidines of formula (I): | 08-20-2009 |
Adrian John Folkes, Basel CH
| Patent application number | Description | Published |
|---|---|---|
| 20110053935 | FUSED PYRIDINES ACTIVE AS INHIBITORS OF C-MET - Fused pyridines of formula (I) and the pharmaceutically acceptable salts thereof have activity as inhibitors of c-Met and may thus be used to treat various diseases and disorders including cancer. Processes for synthesizing the compounds are also described. | 03-03-2011 |
Lisa K. Folkes, Buckinghamshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090137687 | Compositions and Methods With Enhanced Therapeutic Activity - This invention relates to novel tricyclic quinone and catechol compositions, compositions containing prodrugs of tricyclic quinone and catechol compositions, and methods of use for the treatment of solid tumor cancers and other vascular proliferative disorders. In certain aspects, the compositions of the invention are capable of generating both a vascular targeting effect and tumor cell cytotoxicity (e.g., by oxidative stress) in order to achieve an enhanced anti-tumor response in a patient. | 05-28-2009 |
Ronald P. Folkes, Dallas, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090086621 | Correlating Label Switched Paths Of A Pseudowire - In one embodiment, correlating label switched paths of a pseudowire includes receiving a first message at a second label switching router. The first message is sent from a first label switching router and includes a pseudowire identifier and a first label switched path identifier. The pseudowire identifier identifies a pseudowire, and the first label switched path identifier identifies a first label switched path that implements the pseudowire. A second message is sent from the second label switching router to the first label switching router. The second message comprises the pseudowire identifier and a second label switched path identifier. The second label switched path identifier identifies a second label switched path that implements the pseudowire. | 04-02-2009 |
| 20090086633 | Using A Link-State Advertisement To Inform Nodes Of The Availability Of Traffic Management Resources - In one embodiment, informing nodes of traffic management resource availability includes determining a number of available traffic management resources at a first node, where a traffic management resource tracks usage of bandwidth by a tunnel at the first node. The number of available traffic management resources is recorded in a link-state advertisement. The link-state advertisement is sent to one or more second nodes. | 04-02-2009 |
Ronald P. Folkes, Addison, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090052445 | System and Method for Synchronizing Packet Forwarding Information - In accordance with the teachings of the present invention, a system and method for synchronizing packet forwarding information is provided. In a particular embodiment, the system includes a control processor configured to implement a control plane to generate first forwarding information and transfer the first forwarding information to an active forwarding table of a network processor. The system also includes a network processor configured to implement a forwarding plane to receive packets and use the first forwarding information in the active forwarding table to forward the received packets to one or more network devices. After the control plane is restarted, the control processor is further configured to use the restarted control plane to generate second forwarding information and incrementally update the first forwarding information in the active forwarding table with the second forwarding information while the network processor's forwarding plane continues to forward traffic. | 02-26-2009 |
| 20090086632 | Using A Link Attribute To Inform Nodes Of The Availability Of Traffic Management Resources - In one embodiment, informing nodes of traffic management resource availability includes establishing whether there is an available traffic management resource at a first node, where a traffic management resource tracks usage of bandwidth by a tunnel at the first node. Whether there is an available traffic management resource is recorded in a traffic management link attribute. The traffic management link attribute is sent to second nodes to inform the second nodes of whether there is an available traffic management resource at the first node. | 04-02-2009 |