Fogal
James M. Fogal, Houston, TX US
Patent application number | Description | Published |
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20080314137 | METHODS AND APPARATUS FOR MEASURING FORMATION PROPERTIES - This application relates to various methods and apparatus for rapidly obtaining accurate formation property data from a drilled earthen borehole. Quickly obtaining accurate formation property data, including formation fluid pressure, is vital to beneficially describing the various formations being intersected. For example, methods are disclosed for collecting numerous property values with a minimum of downhole tools, correcting and calibrating downhole measurements and sensors, and developing complete formation predictors and models by acquiring a diverse set of direct formation measurements, such as formation fluid pressure and temperature. Also disclosed are various methods of using of accurately and quickly obtained formation property data. | 12-25-2008 |
Stefano Fogal, Altivole IT
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20110137036 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLO[3,4-b]PYRIDINE - The present invention relates to the stereoselective synthesis of (4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine, as well as the conversion thereof, to give Moxifloxacin. Particularly, the present invention relates to a method for the synthesis of (4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine of formula (I) comprising: (a) the optical resolution by enzymatic hydrolysis of the intermediate dialkyl-1-alkylcarbonylpiperidine-2,3-dicarboxylate racemate of formula (II) to give, following isolation, the intermediate dialkyl-(2S,3R)-1-alkylcarbonyl-piperidine-2,3-dicarboxylate of formula (III) in which AIk is a straight or branched C1-C5 alkyl group; (b) the conversion of the intermediate (III) to (4aR,7aS)-1-alkylcarbonylhexahydrofuro[3,4-b]pyridine-5,7-dione of formula (IV) in which AIk has the meanings set forth above; (c) the conversion of the intermediate (IV) to (4aS,7as)-octahydro-1H-pyrrolo[3,4-b]pyridine of formula (I) with an optical purity above 99%. | 06-09-2011 |
20110207172 | PROCESS FOR THE PREPARATION OF TESTOSTERONE - The present invention relates to an industrial process for the reduction of 4-androstene-3,17-dione in order to obtain testosterone using a particularly stable and selective enzyme produced in a recombinant manner. | 08-25-2011 |
Stefano Fogal, Brendola IT
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20150344439 | Convenient Process for the Preparation of Statins - Object of the present invention is an improved process for the preparation of key intermediates for the synthesis of statins. | 12-03-2015 |
Valentina Fogal, La Jolla, CA US
Patent application number | Description | Published |
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20120219502 | METHODS AND COMPOSITIONS FOR TARGETING GC1QR/P32 - Disclosed are compositions and methods useful for targeting gC1q/p32 receptors. The disclosed targeting is useful for delivering therapeutic and detectable agents to cancerous cells, and to areas of inflammation. | 08-30-2012 |