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Flynn, AZ

Charles Flynn, Flagstaff, AZ US

Patent application numberDescriptionPublished
20080281393Bioabsorbable Self-Expanding Endolumenal Devices - The present invention is directed to bioabsorbable self-expanding medical devices for use inside or outside body conduits that self-expand at, or below, normal human body temperature without requisite for a polymeric thermal transition.11-13-2008
20080319367METHOD OF USING A HIGHLY POROUS SELF-COHERED WEB MATERIAL - The present invention is directed to methods of using implantable bioabsorbable non-woven self-cohered web materials having high degrees of porosity, particularly at anastomotic sites. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof.12-25-2008
20090012613Composite Self-Cohered Web Materials - The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof.01-08-2009
20090202611COMPOSITE SELF-COHERED WEB MATERIALS - The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof.08-13-2009
20100010515Composite self-cohered web materials - The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof.01-14-2010
20110089592METHOD OF MAKING POROUS SELF-COHERED WEB MATERIALS - The present invention is directed to a method of making implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting proportionally increased mechanical strength in one or more directions. The web materials often possess a high degree of loft. The web materials can be formed into a variety of shapes and forms suitable for use as implantable medical devices or components thereof.04-21-2011

Patent applications by Charles Flynn, Flagstaff, AZ US

Charles Robert Flynn, Chandler, AZ US

Patent application numberDescriptionPublished
20080293640Polypeptide inhibitors of HSP27 kinase and uses therefor - The present invention provides polypeptide inhibitors of HSP27 kinase, compositions thereof, and methods for using such polypeptides and compositions for various therapeutic uses.11-27-2008
20110028398METHODS FOR TREATING AND LIMITING FIBROTIC DISORDERS AND KELOIDS - The present invention provides methods for treating and/or limiting fibrotic disorders and/or treating or limiting scars selected from the group consisting of keloids and hypertrophic scars comprising administering to an individual in need thereof an amount effective to treat and/or limit scars selected from the group consisting of keloids and hypertrophic scars of a polypeptide comprising an HSP20-related polypeptide.02-03-2011

Gary Flynn, Oro Valley, AZ US

Patent application numberDescriptionPublished
20120136029COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF 2-ARYL PYRIDYLAZOLES - A 2-aryl-pyridylazole compound and derivatives useful in slowing the growth of cancer cells are disclosed. Also disclosed are methods of synthesizing the compound, methods of using pharmaceutical compositions containing the compound as an ingredient to slow the growth of cancer cells, and methods of treating cancer patients with pharmaceutical compositions containing the compound as an ingredient.05-31-2012

Gary A. Flynn, Oro Valley, AZ US

Patent application numberDescriptionPublished
20090137420METHODS, COMPOUNDS AND COMPOSITIONS WITH GENOTYPE SELECTIVE ANTICANCER ACTIVITY - This invention is directed to methods for screening and identification of compounds capable of selectively eliminating cancer cells with specific loss-of-function alterations, including but not limited to mutations, deletions, hypermethylations, and other types of gene silencing. This invention is also directed to novel compounds that selectively eliminate cancer cells with specific loss-of-function alterations. Furthermore, this invention is directed to methods for production and therapeutic use of compounds that selectively eliminate cancer cells with specific loss-of-function alterations.05-28-2009

Gary A. Flynn, Tuscon, AZ US

Patent application numberDescriptionPublished
20080280891Anti-cancer agents and uses thereof - The present invention is in the area of novel compounds and salts thereof, their syntheses, and their use as anti-cancer agents. The compounds include compounds of Formula I:11-13-2008

Gary A. Flynn, Tucson, AZ US

Patent application numberDescriptionPublished
20080221169AQUAPORIN MODULATORS AND METHODS OF USING THEM FOR THE TREATMENT OF EDEMA AND FLUID IMBALANCE - Compounds, including 3-carboxy aryl sulfonamide compounds, which agonize or antagonize aquaporin channels and methods of using them to treat disorders or diseases mediated by aquaporins.09-11-2008
20090093479ANTI-CANCER AGENTS AND USES THEREOF - The present invention is in the area of novel compounds and salts thereof, their syntheses, and their use as anti-cancer agents. The compounds include compounds of Formula I:04-09-2009
20090186893IRE-1alpha INHIBITORS - Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.07-23-2009
20110065162IRE-1alpha INHIBITORS - Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.03-17-2011
20110172195AQUAPORIN MODULATORS AND METHODS OF USING THEM FOR THE TREATMENT OF EDEMA AND FLUID IMBALANCE - Compounds, including 3-carboxy aryl sulfonamide compounds, which agonize or antagonize aquaporin channels and methods of using them to treat disorders or diseases mediated by aquaporins.07-14-2011
20110281850INTRACELLULAR KINASE INHIBITORS - Intracellular kinase inhibitors and their therapeutic uses for patients with T cell malignancies, B cell malignancies, autoimmune disorders, and transplanted organs.11-17-2011

Patent applications by Gary A. Flynn, Tucson, AZ US

Patrick Flynn, Phoenix, AZ US

Patent application numberDescriptionPublished
20100319653REDUCED FRICTION ROTARY COMBUSTION ENGINE - An axial vane rotary combustion engine includes various performance improving features. These features include fluid film bearings that enable the vane assemblies to react large loads, a dual vane assembly configuration that share vane loads over two cylindrical bearing supports, a vane actuation mechanism that provides positive actuation even with cam surface tolerance variations, and various features to reduce friction to thereby improve efficiency and reduce heat generation.12-23-2010

Roger Flynn, Tempe, AZ US

Patent application numberDescriptionPublished
20100314093VARIABLE HEAT EXCHANGER - Various apparatus and methods for thermally managing a heat generating device. In one aspect, a method of thermally managing a heat generating device is provided that includes placing a heat exchanger in thermal communication with the heat generating device. The heat exchanger has an interior space. A membrane is in the interior space between a first chamber and a second chamber. The membrane has a gas impermeable portion and at least one gas permeable portion to enable vapor bubbles in the second chamber to pass through the membrane at the at least one gas permeable portion and into the first chamber. A liquid is moved through the second chamber.12-16-2010