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Flotte

Didier Flotte, Metz FR

Patent application numberDescriptionPublished
20110255373Non Destructive Testing Device and Method for Detecting Possible Anomalies of a Wall Thickness - The invention relates to a nondestructive testing device for detecting possible thickness anomalies (Ve) of a wall (P), this device comprising a sensor (10-20-2011

Laurent Flotte, Aurade FR

Patent application numberDescriptionPublished
20100004801Air Navigation Aid Method and System Making it Possible to Maintain Vertical Margins - The invention relates to a calculation method for an aircraft navigation aid system making it possible to maintain a vertical safety margin with an obstruction profile, the aircraft comprising a navigation system, an automatic piloting system, a database system and a display device, characterized in that the method comprises the following steps: calculation of an obstruction altitude profile, calculation of a vertical safety margin with respect to the obstruction profile, of a plurality of vertical safety trajectories and of the respective flight setpoints for the aircraft to execute the trajectories, selection of the flight setpoints making it possible to maintain the aircraft as close as possible to the obstruction profile while maintaining between the aircraft and the obstruction profile at least the vertical safety margin, filtering of the flight set point values so that the variation of the values of the setpoints does not exceed a variation difference in a duration predefined in the system.01-07-2010
20100106419METHOD AND DEVICE FOR AIDING NAVIGATION FOR AN AIRCRAFT IN RELATION TO OBSTACLES - The invention relates to a method of presenting zones at risk for an aircraft comprising a system of databases, a processor, an anticollision device and a viewing device, wherein to display on the viewing device the zones at risk in relation to the obstacles, the processor carries out the steps of: acquiring obstacle data, the data corresponding to obstacles situated in the aircraft's close displacement zone; calculating the risk of collision with each of the obstacles of the displacement zone; calculating the limits of the zones at risk of collision in the close displacement zone, these limits representing the positions from which the anticollision device might possibly produce collision alerts in relation to the obstacles if the aircraft were to steer towards the obstacle while maintaining the instantaneous flight parameters; and displaying the limits of zones at risk.04-29-2010
20100318295Method and Device for Displaying the Limits of Flight Margins for an Aircraft - A method of displaying, for a system for anti-collision monitoring of an aircraft, the limits of flight margins in relation to obstructions located in a flight zone, and a device for displaying the limits of operational flight margins and the limits of alert zones, is provided. The operational flight margins in the flight zones not initially envisaged, and the limits of the alert zones around the trajectory of the aircraft, are presented.12-16-2010
20110153212Device and Method for the Coherent Management of Data Deriving from Surveillance Systems of an Aircraft - A device for the coherent management of data deriving from different surveillance systems of an aircraft includes: a flight management system, the function of which is to assist the crew in following a flight plan of the aircraft and an associated trajectory; a surveillance system, the function of which is to detect any obstacles in proximity to the aircraft; a warning management system, the function of which is to detect abnormal situations and to display for the crew, where appropriate, warnings, such as potentially critical alarms or non-critical alerts, and the associated procedures to be followed when such exist; in which said flight management system, said surveillance system and said warning management system are interconnected and cooperate so that at least the warning management system has access to the flight plan of the aircraft, and is configured to display for the crew a summary of the situation when the surveillance system detects an obstacle that the aircraft should avoid according to the flight plan, and to not display, consequently, unnecessary warnings.06-23-2011
201102108713D Navigation Aid System and Display for Same - The invention relates to an aircraft navigational aid system with 3D display including an anti-collision device, with means of storing data representing obstructions, means for calculating a representation of the obstructions in a three-dimensional space and a device for displaying the obstructions data in three dimensions. The system includes means for augmenting the display of the representation of the area of hazardous obstructions with at least two indicator objects for the said area of hazardous obstructions disposed together in such a manner as to form a third object targeting the localization of the point in the area of hazardous obstructions closest to the aircraft. The invention also relates to the method of display of the indicator objects in a three-dimensional display.09-01-2011
20110251741METHOD OF ALERT CALCULATION FOR AN AIRCRAFT GROUND PROXIMITY WARNING SYSTEM - The invention relates to a method of alert calculation for an aircraft obstruction proximity warning system including a step for detecting a hazardous flight situation capable of triggering an alert as a function of a data signal representing the change in height below the aircraft, including, prior to the step of detection, a step for converting the data signal representing the change in height as a function of information representative of the vertical profile of the obstructions below the aircraft.10-13-2011

Terence Flotte, Holden, MA US

Patent application numberDescriptionPublished
20120137379NOVEL AAV'S AND USES THEREOF - The invention in some aspects relates to recombinant adeno-associated viruses having distinct tissue targeting capabilities. In some aspects, the invention relates to gene transfer methods using the recombinant adeno-associate viruses. In some aspects, the invention relates to isolated AAV capsid proteins and isolated nucleic acids encoding the same.05-31-2012

Terence R. Flotte, Gainesville, FL US

Patent application numberDescriptionPublished
20090186002rAAV-delivered alpha-1-antitrypsin compositions and method for the treatment and prevention of diabetes - The subject invention concerns materials and methods for gene therapy. One aspect of the invention pertains to vectors which can be used to effect genetic therapy in animals or humans having genetic disorders where expression of high levels of a protein of interest are required to treat or correct the disorder. The subject invention also pertains to methods for treating animals or humans in need of gene therapy to treat or correct a genetic disorder. The materials and methods of the invention can be used to provide therapeutically effective levels of a protein that is non-functional, or that is absent or deficient in the animal or human to be treated. In one embodiment, the materials and methods can be used to treat alpha-1-antitrypsin deficiency.07-23-2009

Terence R. Flotte, Alachua, FL US

Patent application numberDescriptionPublished
20090111766RAAV VECTOR-BASED COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MAMMALIAN DISEASES - Disclosed are recombinant adeno-associated viral (rAAV) vector compositions that are expressed in selected mammalian cells, such as pancreatic islets cells, and that encode one or more mammalian serpin or cytokine polypeptides having therapeutic efficacy in the amelioration, treatment and/or prevention of interleukin deficiencies, such as for example diabetes, and related diseases of the pancreas. Also disclosed are methods and compositions for preventing diabetes in a mammal, reducing the rate of disease progression, and ameliorating the symptoms of diabetes in humans at risk for developing such conditions.04-30-2009

Patent applications by Terence R. Flotte, Alachua, FL US