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Florent
Frederic Henri Florent, Samoreau FR
| Patent application number | Description | Published |
|---|---|---|
| 20090238982 | REINFORCEMENT OF GLASS-CERAMIC OR GLASS PLATES AND REINFORCED PLATES - Disclosed in the present application include: (i) a method of reinforcing plates, having two approximately parallel main sides, of a glass-ceramic or a glass, said method comprising fixing at least one layer comprising at least one (co)polymer which is resistant to high temperature onto at least one part of the surface of at least one of their two main sides; as well as (ii) reinforced plates of this type. | 09-24-2009 |
Hube Florent, Winnipeg CA
| Patent application number | Description | Published |
|---|---|---|
| 20090216005 | Small Breast Epithelial Mucin Gene Promoter - The human small breast epithelial mucin gene promoter is analyzed and regions corresponding to a minimum promoter element for breast cell-specific expression, an enhancer and a negative regulatory element are identified. | 08-27-2009 |
Jean-Claude Florent, Gif-Sur-Yvette FR
| Patent application number | Description | Published |
|---|---|---|
| 20090214438 | METHODS AND COMPOSITIONS FOR THE PREPARATION AND USE OF TOXIN CONJUGATES - The present invention relates to methods for the preparation of toxin conjugates that are useful in vaccination and other therapies and diagnostics. In particular, methods are provided that involve a [3+2] cycloaddition between a first reactive unsaturated group on a toxin moiety and a second reactive unsaturated group on a bioactive moiety. Also provided are conjugates that are formed through this conjugation method, pharmaceutical compositions comprising these conjugates, and methods of using these pharmaceutical compositions for the treatment or diagnostic of antigen-related conditions, including tumors and infections. | 08-27-2009 |
| 20090246772 | NOVEL DIBENZO[c,h][1,5]NAPHTHYRIDINES AND THEIR USE AS DNA PROBES - The present invention concerns novel dibenzo[c,h][1,5]naphthyridine of formula (I) and their use as DNA probes, as well as the methods for marking DNA using the same. | 10-01-2009 |
| 20100329992 | SHIGA TOXIN B-SUBUNIT AS A VECTOR FOR TUMOR DIAGNOSIS AND DRUG DELIVERY TO GB3 EXPRESSING TUMORS - The invention relates to new compounds for cancer therapy or diagnosis and more specifically to the use of a non-toxic B subunit of Shiga toxin mutant as a vector for diagnostic products or drugs in over-expressing Gb | 12-30-2010 |
| 20110152252 | SHIGA TOXIN B-SUBUNIT/CHEMOTHERAPEUTICS CONJUGATES - The present invention relates to the use of a Shiga toxin B-subunit moiety as carrier for therapeutic agents, for example, anti-cancer agents such as anti-cancer agents that require intracellular uptake to exert their anti-cancer effects. In particular, the present invention provides conjugates comprising a Shiga toxin moiety covalently linked to an anti-cancer agent through a self-immolative spacer, and methods of using such conjugates to increase cellular uptake and/or specificity for cancer cells of the anti-cancer drug. Also provided are methods of treatment involving administration of such conjugates, and pharmaceutical compositions and kits useful for carrying out such methods of treatment. | 06-23-2011 |
Raoul Florent, Eindhoven FR
| Patent application number | Description | Published |
|---|---|---|
| 20100049038 | CARDIAC ROADMAPPING - According to an exemplary embodiment of the present invention, a cardiac roadmapping technique is provided, in which a static roadmap is built onto which a view of the intervention device is projected at the correct location. This new viewing mode combines the advantages of both roadmapping, i.e. accurate localization, and the advantages of a motion-free view, i.e. maximum readability. | 02-25-2010 |
Roy Florent, Langley CA
| Patent application number | Description | Published |
|---|---|---|
| 20080276415 | Vacuum floor brush - The embodiment of this disclosure in one form is a plurality of tabs for the specific use of vacuuming hardwood, laminate, linoleum, marble, tile and other hard surface floors. The apparatus in one form is designed to fit and function in a universal vacuum head, on built-in or canister style vacuum cleaners. The tabs may be made of several materials, including felt, Teflon, and other fluorine-containing polymers. | 11-13-2008 |
Thierry Florent, Napa, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100056922 | Method and diagnostic ultrasound apparatus for determining the condition of a person's artery or arteries - A method and diagnostic apparatus for determining the condition of a patient's artery or arteries by the use of an ultrasound imaging system which operates in the triplex mode, with a B-mode image of a selected artery location, an A-mode perpendicular to the plane of the artery, at the selected location and a pulsed doppler, at the selected location at an angle to the plane of the artery, with the signals combined, the artery physically or chemical stimulated, the percent dilation of the artery is determined after stimulation, and therefore the condition of the artery is obtained. | 03-04-2010 |