Patent application number | Description | Published |
20110020843 | LABEL-FREE METHODS RELATED TO PHOSPHODIESTERASES - 196. Disclosed are methods of incubating cells on biosensors, and methods using the disclosed incubation techniques to identify PDE4 modulators. | 01-27-2011 |
20110027888 | Coated Fibers for Culturing Cells - A coated fiber for cell culture includes a fiber core having an exterior surface and a polymeric coating suitable for culturing cells disposed on at least a portion of the exterior surface of the fiber core. A polypeptide may be conjugated to the polymeric coating. A method for forming the coated fiber includes coating a polymer layer to an exterior surface of a fiber core to produce the coated fiber. The coating may occur as the fiber is being drawn. | 02-03-2011 |
20110027889 | Synthetic Microcarriers for Culturing Cells - A coated microcarrier for cell culture includes a microcarrier base and a polymeric coating grafted to the base via a polymerization initiator. A method for forming the coated microcarrier includes (i) conjugating a polymerization initiator to the microcarrier base to form an initiator-conjugated microcarrier base; (ii) contacting the initiator-conjugated microcarrier base with monomers; and (iii) activating the initiator to initiate polymerization and graft the polymer to the base. | 02-03-2011 |
20110028345 | METHODS TO CHARACTERIZE CELL REPROGRAMMING AND USES THEREOF - Disclosed are label free biosensors and methods using these to observe stem cells and for the analysis of stem and related cells. | 02-03-2011 |
20110207789 | METHODS RELATED TO CASEIN KINASE II (CK2) INHIBITORS AND THE USE OF PURINOSOME-DISRUPTING CK2 INHIBITORS FOR ANTI-CANCER THERAPY AGENTS - Disclosed are methods related to label-free biosensor cellular assays to classify multienzyme complex modulators in live cells. Disclosed are also methods related to the identification of purinosome disrupting Casein Kinase II (CK2) inhibitors, and methods related to the use of purinosome disrupting CK2 inhibitors as therapeutic agents for modulating CK2 activity and purine synthesis pathway, and for improving prevention and treatment of CK2 associated cancers, viral infection and inflammation conditions. | 08-25-2011 |
20120034435 | COATED, ANTIMICROBIAL, CHEMICALLY STRENGTHENED GLASS AND METHOD OF MAKING - The disclosure is directed to a chemically strengthened glass having antimicrobial properties and to a method of making such glass. In particular, the disclosure is directed to a chemically strengthened glass with antimicrobial properties and with a low surface energy coating on the glass that does not interfere with the antimicrobial properties of the glass. The antimicrobial has an Ag ion concentration on the surface in the range of greater than zero to 0.047 μg/cm | 02-09-2012 |
20120058556 | High Surface Area Substrate for Cell Culture - A cell culture microcarrier includes (1) a polystyrene microcarrier base having a remnant of a carboxylic acid group, and (ii) a polypeptide conjugated to the base via the remnant of the carboxylic acid group. The polypeptide may contain a cell adhesive sequence, such as RGD. Cells cultured with such microcarriers exhibit peptide-specific binding to the microcarriers. | 03-08-2012 |
20120190620 | METHODS TO IDENTIFY TARGETS AND MOLECULES REGULATING PURINOSOMES AND THEIR USES - The present invention discloses methods to identify targets, pathways and molecules regulating purinosomes and their uses for treating pathophysiological disorders associated with purinosomes. Disclosed are methods related to both label-free cellular assays and fluorescence imaging to confirm the regulatory roles of various targets and molecules in purinosome dynamics. Disclosed are methods to classify molecules and the uses of these molecules for different indications. Specifically, the purinosome-disrupting molecules can be used for improved prevention and treatment of cancer development. | 07-26-2012 |
20120288912 | SYNTHETIC MICROCARRIERS FOR CULTURING CELLS - A coated microcarrier for cell culture includes a microcarrier base and a polymeric coating grafted to the base via a polymerization initiator. A method for forming the coated microcarrier includes (i) conjugating a polymerization initiator to the microcarrier base to form an initiator-conjugated microcarrier base; (ii) contacting the initiator-conjugated microcarrier base with monomers; and (iii) activating the initiator to initiate polymerization and graft the polymer to the base. | 11-15-2012 |
20140017462 | ANTIMICROBIAL ACTION OF Cu, CuO and Cu20 NANOPARTICLES ON GLASS SURFACES AND DURABLE COATINGS - A transparent cover glass for applications such as, but not limited to, touch screen devices that embody antimicrobial properties that include s being antibacterial, antifungal, and antiviral. The antimicrobial glasses contain nanoparticles of Cu or Cu | 01-16-2014 |
20140079807 | ANTIMICROBIAL ACTION OF COPPER IN GLASS - The disclosure is directed to glass compositions that incorporate copper into an otherwise homogeneous glass and to a method for making such glass. This incorporation of the copper into the glass composition imparts significant antimicrobial activity to the glass. A method of making a copper-containing glass article comprises: batching a glass batch comprising: 40-85 SiO | 03-20-2014 |
20140212467 | Antimicrobial Composite Material - The present disclosure is directed to an antimicrobial composite material, and more particularly to an antimicrobial composite material comprising particles having a metal or metal alloy core and a porous inorganic material shell, coatings including the antimicrobial composite material, and methods of making the same. In some embodiments, Cu—SiO | 07-31-2014 |