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Fleming, GB
Adam John Fleming, Cheshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20110103576 | TELEPHONE CALL HANDLING - A telephone handset is provided with a user interface which includes a display unit, audio output unit and various user actuable keys. A phone controller implements and responds to instructions from the user interface. Where the instructions from the user interface request the connection of a call, the phone controller connects the handset to a PSTN via one of a plurality of connection means provided. Similarly, in the event of an incoming call connection request received via any one of the connection means, the phone controller enables the connection of the call. The user may choose to accept or reject the connection using the interface. The handling of an incoming or outgoing call is determined by a connection routing engine. The connection routing engine comprises an identification unit, a rules unit, a comparison unit and an enabling unit. | 05-05-2011 |
Alan Duncan Fleming, Aberdeen GB
| Patent application number | Description | Published |
|---|---|---|
| 20100142766 | Image Analysis - Systems and methods of processing a retinal input image to identify an area representing a predetermined feature. One method comprises processing said retinal input image to generate a plurality of images, each of said plurality of images having been scaled by a respective associated scaling factor, and each of said plurality of images having been subjected to a morphological closing operation with a two-dimensional structuring element arranged to affect the image substantially equally in at least two perpendicular directions. The plurality of images are processed to identify said area representing said predetermined feature. | 06-10-2010 |
| 20100142767 | Image Analysis - Systems and methods of processing a retinal input image to identify an area representing a predetermined feature. One method comprises processing said retinal input image to generate a plurality of images, each of said plurality of images having been scaled by a respective associated scaling factor, and each of said plurality of images having been subjected to a morphological closing operation with a two-dimensional structuring element arranged to affect the image substantially equally in at least two perpendicular directions. The plurality of images are processed to identify said area representing said predetermined feature. | 06-10-2010 |
| 20120027275 | DISEASE DETERMINATION - A method of generating output data providing an indication of the presence or absence of disease from at least one retinal image of a patient. The method comprises receiving first data associated with detection of a first lesion type in the at least one image, receiving second data associated with detection of a second lesion type in the at least one image, and receiving third data associated with detection of a third lesion type in the at least one image, wherein at least one of said first data, said second data and said third data is a quantitative indication associated with detection of the respective lesion type in said image. The first data, second data and third data are combined to generate the output data providing an indication of the presence or absence of disease. | 02-02-2012 |
Alistair Fleming, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20100168522 | SURGICAL ACCESS ASSEMBLY - A surgical access assembly configured and dimensioned for positioning within an intercostal space defined between a patient's adjacent ribs to facilitate passage of a surgical instrument into an internal work site. The surgical access assembly includes a body portion that may be either partially or wholly formed from a resilient material such that the surgical access assembly is resiliently deformable to facilitate conformity with the intercostal space in order to minimize the application of force to the patient's tissue upon insertion and removal of the access assembly and manipulation of the surgical instrument. | 07-01-2010 |
Alistair I. Fleming, Cambridgeshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090292281 | Surgical instrument - A device for morcellating tissue within a body cavity of a patient comprises a stationary tube having a distal end portion, and a bipolar electrosurgical electrode assembly located at the distal end of the tube. The electrosurgical electrode assembly comprises first and second electrodes separated by an insulation member. When an electrosurgical cutting voltage is applied to the electrode assembly, and relative movement is initiated between the tube and the tissue, a core of severed tissue is formed within the tube such that it can be removed from the body cavity of the patient. The tube comprises a twin-walled construction with an inner wall, an outer wall and an air gap therebetween. This twin-walled construction reduces the heat that is able to travel proximally along the tube. | 11-26-2009 |
| 20110184409 | SURGICAL INSTRUMENT - A device for morcellating tissue within a body cavity of a patient comprises a stationary tube ( | 07-28-2011 |
Alistair Ian Fleming, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20110190779 | SURGICAL RETRIEVAL APPARATUS - A surgical retrieval apparatus having an elongate member and a support member extending from the elongate member movable between a collapsed insertion position and an expanded position. A retrieval bag extends from the support member and has a first end and a closed second end, the first end movable to an open configuration when the support member moves to the expanded position. A net is positioned within the retrieval bag and detachably connected thereto. | 08-04-2011 |
| 20110190781 | SURGICAL RETRIEVAL APPARATUS - A surgical retrieval apparatus includes an elongate flexible tubular member having a distal opening and a lumen and a support member having a chamber formed therein in fluid communication with the tubular member and movable from a first position to a second expanded position in response to introduction of fluid into the chamber. A retrieval bag extends from the support member and has a first end and a closed second end. The first end of the retrieval bag is movable to an open configuration when the expandable member transitions from the first position to the second expanded position. | 08-04-2011 |
| 20110190782 | SURGICAL RETRIEVAL APPARATUS - A surgical retrieval apparatus includes an elongate tubular member having a drive rod slidably disposed therein. A support member is operably coupled to a distal end of the drive rod. A pouch is attached to the support member and has a closed end and an open end. The pouch is securely coupled to the support member. | 08-04-2011 |
| 20110264091 | APPARATUS AND METHOD FOR SEALING SPECIMEN FOR RETRIEVAL - A method for modifying a tissue specimen includes providing a specimen modifying apparatus configured to modify the specimen to thereby prevent seeding from the specimen. The specimen modifying apparatus is inserted through an opening in tissue and positioned adjacent the tissue specimen to be modified. The tissue modifying apparatus is activated to modify the tissue specimen to thereby inhibit seeding from the tissue specimen. | 10-27-2011 |
| 20110270265 | SYSTEM AND METHOD FOR REMOVING EXCISED TISSUE - A method and system for removing tissue from a body cavity is provided. The system includes a retrieval bag that is insertable through a first incision in tissue and includes open and closed ends. A surgical instrument is insertable into the body cavity and configured to grasp and excise a sample/specimen from within the body cavity and selectively substantially seal the retrieval bag. A fluid circulator in fluid communication with the surgical instrument and the open end of the retrieval bag is configured to evacuate gaseous matter from within the body cavity and into the open end of the retrieval bag such that the retrieval bag substantially encircles the excised tissue specimen. | 11-03-2011 |
Alistair Lan Fleming, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20110190780 | SURGICAL RETRIEVAL APPARATUS - A method of retrieving a tissue specimen comprising inserting a surgical retrieval apparatus through an opening in a patient's skin, the surgical retrieval apparatus including a support member and a retrieval bag extending from the support member and having an opening to receive the tissue specimen. A net is introduced into the retrieval bag and placed over the tissue specimen. The net and retrieval bag are removed from the patient's body to remove the tissue specimen. | 08-04-2011 |
Angus Fleming, Berkshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20120045339 | ROTOR BLADES - A rotor blade comprises a blade portion, a root portion ( | 02-23-2012 |
Craig Fleming, South Lanarkshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090201820 | METHOD FOR PREDICTING A FAULT IN A SECURITY SYSTEM - A method for predicting a fault in a wireless communication path between at least one transmitter and a receiver. The method comprises detecting an initial value of a characteristic of a reception signal or an initial value of a characteristic of a wireless communication path, calculating a running average of the same characteristic for preset period of time, comparing the initial value with the calculated running average; and displaying an indication based upon an analysis of the comparing. The indication is transmitted to a remote site for response. The characteristic can be signal strength, noise and a S/N ratio. | 08-13-2009 |
Ian Fleming, Angus GB
| Patent application number | Description | Published |
|---|---|---|
| 20090274773 | ANTIPROLIFERATIVE COMBINATION COMPRISING CYC-682 AND A CYTOTOXIC AGENT - A first aspect of the invention relates to a combination comprising 2′-cyano-2′-deoxy-N4-palmitoyl-1-beta-D-arabi-nofuranosyl-cytosine, or a metabolite thereof, or a pharmaceutically acceptable salt thereof, and a cytotoxic agent selected from (a) a vinca alkaloid; (b) a taxane; (c) a cytosine analogue; (d) an anthracycline; and (e) a platinum antineoplastic agent. A second aspect of the invention relates to a pharmaceutical product comprising the above combination as a combined preparation for simultaneous, sequential or separate use in therapy. A third aspect of the invention relates to a method for treating a proliferative disorder, said method comprising simultaneously, sequentially or separately administering the above combination. | 11-05-2009 |
| 20090306098 | COMBINATION OF ROSCOVITINE AND A HDCA INHIBITOR TO TREAT PROLIFERATIVE DISEASES - A first aspect of the invention relates to a combination comprising roscovitine, or a pharmaceutically acceptable salt thereof, and a HDAC inhibitor selected from sodium butyrate, or a prodrug thereof, suberoylanilide hydroxamic acid (SAHA), sodium valproate and trichostatin A (TSA). A second aspect of the invention relates to a pharmaceutical product comprising roscovitine, or a pharmaceutically acceptable salt thereof, and a HDAC inhibitor selected from sodium butyrate, or a prodrug thereof, suberoylanilide hydroxamic acid (SAHA), sodium valproate and trichostatin A (TSA) as a combined preparation for simultaneous, sequential or separate use in therapy. A third aspect of the invention relates to a method for treating a proliferative disorder, said method comprising simultaneously, sequentially or separately administering roscovitine, or a pharmaceutically acceptable salt thereof, and a HDAC inhibitor selected from sodium butyrate, or a prodrug thereof, suberoylanilide hydroxamic acid (SAHA), sodium valproate and trichostatin A (TSA) to a subject. | 12-10-2009 |
| 20100069291 | COMBINATION COMPRISING CNDAC (2'-CYANO-2'-DEOXY-N4-PALMITOYL-1-BETA-D-ARABINOFURANOSYL-CYTOSINE) AND A CYTOTOXIC AGENT - A first aspect of the invention relates to a combination comprising 2′-cyano-2′-deoxy-N | 03-18-2010 |
| 20100143350 | COMBINATION OF A PURINE-BASED CDK INHIBITOR WITH A TYROSINE KINASE INHIBITOR AND USE THEREOF IN THE TREATMENT OF PROLIFERATIVE DISORDERS - The present invention relates to combination comprising (i) an ErbB inhibitor; and (ii) a CDK inhibitor, or a pharmaceutically acceptable salt thereof, selected from: (a) roscovitine; (b) 3-{9-isopropyl-6-[(pyridin-3-ylmethyl)-amino]-9H-purin-2-ylamino}-2-methyl-pentan-2-ol; (c) 3-{9-isopropyl-6-[(pyridin-3-ylmethyl)-amino]-9H-purin-2-ylamino}-pentan-2-ol; and (d) (2R,3S-3-(6-((4,6-dimethylpyridin-3-ylmethylamino)-9-isopropyl-9H-purin-2-ylamino)pentan-2-ol. | 06-10-2010 |
Ian Neil Fleming, Angus GB
| Patent application number | Description | Published |
|---|---|---|
| 20110207692 | COMBINATIONS OF SAPACITABINE OR CNDAC WITH DNA METHYLTRANSFERASE INHIBITORS SUCH AS DECITABINE AND PROCAINE - A first aspect of the invention relates to a combination comprising a DNA methyltransferase inhibitor and 1-(2-C-cyano-2-dioxy-β-D-arabino-pentofuranosyl)-N4-palmitoyl cytosine, or a metabolite thereof. A second aspect of the invention relates to a pharmaceutical product comprising a DNA methyltransferase inhibitor and 1-(2-C-cyano-2-dioxy-β-D-arabino-pentofuranosyl)-N4-palmitoyl cytosine, or a metabolite thereof, as a combined preparation for simultaneous, sequential or separate use in therapy. A third aspect of the invention relates to a method of treating a proliferative disorder, said method comprising simultaneously, sequentially or separately administering a DNA methyltransferase inhibitor and 1-(2-C-cyano-2-dioxy-β-D-arabino-pentofuranosyl)-N4-palmitoyl cytosine, or a metabolite thereof, to a subject. | 08-25-2011 |
Juliette Fleming, Linlithgow GB
| Patent application number | Description | Published |
|---|---|---|
| 20090241115 | APPLICATION TRANSLATION COST ESTIMATOR - The invention provides a computer-implemented method for estimating the cost of translating a body of text associated with a software application, wherein the software application is configured to perform one or more tasks. In particular the method comprises: determining one or more content types associated with the body of text, wherein each content type has an average word count per content unit; assigning a number of tasks associated with the software application to each content type, wherein each task has an associated number of content units; generating an estimated word count for each content type based on the number of tasks assigned to each content type and the average word count per unit for each content type; summing the estimated word count for each content type to generate an estimated word count for the body of text; and calculating an estimated translation cost based on the estimated word count. | 09-24-2009 |
| 20090300494 | USER ASSISTANCE PANEL - A system for providing user assistance receives a request for help content for a first component of a plurality of components displayed on a user interface page. The system generates a user assistance panel that is displayed simultaneously with the user interface page without substantially obscuring the user interface page. The user assistance panel includes the help content for the first component and a heading for a second component of the plurality of components that has associated help content. | 12-03-2009 |
Keith Fleming, Leicester GB
| Patent application number | Description | Published |
|---|---|---|
| 20090272205 | MODULAR SENSOR ASSEMBLY - A modular sensor assembly for performing measurement or calibration is disclosed, comprising a sensing module comprising a threaded spigot, a first slip ring conductive track, and a second slip ring conductive track; a base module comprising a threaded receptacle, a first conductor, and a second conductor; wherein the sensing module is detachably mounted to the base module by rotating the threaded spigot into the threaded receptacle thereby forming a first electrical connection between the first slip ring conductive track and the first conductor, and a second electrical connection between the second slip ring conductive track and the second conductor. | 11-05-2009 |
Peter Fleming, Newbury GB
| Patent application number | Description | Published |
|---|---|---|
| 20090102713 | Geolocation Methods and Apparatus - Methods and associated apparatus and programs for computers for operating geolocation devices are provided. The methods include determining the duration of a time interval during which the device is configured to remain active, responsive to a comparison between an estimate of benefit of remaining on for that time interval and an estimate of cost of remaining on for that time interval. The estimates of cost and benefit may be determined in response to user-selected parameters where by the end-user may effect a trade-off between battery life and receiver sensitivity. The methods also include varying the maximum duration of each listening period whereby to conserve battery power. | 04-23-2009 |
Peter Mark Fleming, Berkshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20100188286 | TIME REFERENCE SYSTEM - A time reference system for generating a time reference from signals produced by a global navigation satellite constellation has a satellite signal receiver to receive and down-convert code-modulated signals from a plurality of satellites and a correlator to track and decode the down-converted signals to provide signals containing partial pseudo-range measurements for respective satellites. A data processing arrangement receives assistance data from an external source and performs data-bit synchronisation in which bit edges of a low frequency data bit stream carried by the received satellite signals are identified, to perform a preliminary position-velocity-time solution to provide an approximate time reference, and to perform auto-correlation of pre-selected data sequences in the data stream to resolve time ambiguities thereby to compute a precise time reference signal in weak received signal conditions. The pre-selected data sequences may be the repeated data preamble in the GPS navigation message constituted by the data stream. | 07-29-2010 |
Steve David Fleming, Hockley GB
| Patent application number | Description | Published |
|---|---|---|
| 20100230451 | ROOF BAR FOR A MOTOR VEHICLE - A roof bar ( | 09-16-2010 |
| 20100230452 | ROOF BAR FOR A MOTOR VEHICLE - A roof bar ( | 09-16-2010 |
| 20100230453 | ROOF BAR FOR A MOTOR VEHICLE - A roof bar ( | 09-16-2010 |
| 20110103926 | Vehicle Storage/Loading System for Sheets - A motor vehicle having an assembly for loading sheet material includes a cargo area having a loading opening and a bulkhead located at an opposite end of the cargo area from the loading opening. Also included is a passenger compartment located at a forward region of the vehicle. Further included is at least one fixed end stop located proximate a rear area of the cargo area. Yet further included is at least one load assist strip, where a first end of the strip is mounted to the bulkhead, wherein the strip extends rearward to a second end of the strip that is mounted to the end stop. | 05-05-2011 |
| 20110148134 | MOVABLE BULKHEAD SYSTEM TO INCREASE LOAD CAPACITY OF A VEHICLE - A moveable bulkhead | 06-23-2011 |
Susannah Fleming, Oxon GB
| Patent application number | Description | Published |
|---|---|---|
| 20100298730 | METHOD AND APPARATUS FOR MEASURING BREATHING RATE - An example method and apparatus for measuring the breathing rate from the photoplethysmogram signal (PPG) uses auto-regressive modelling of the signal. The PPG signal is windowed in overlapping windows of typically 30 seconds' length, overlapping by 25 seconds, to obtain discrete sections of the signal and each section is low-pass filtered, downsampled and detrended and then AR modelled using an all-pole auto-regressive (AR) model. The AR model allows identification of the dominant frequencies in the signal and the pole corresponding to the breathing rate is identified by considering its magnitude and the breathing rate it represents. Each 30 second window gives a breathing rate estimate and use of successive windows displaced by 5 seconds results in a breathing rate estimate every 5 seconds. The time series of breathing rate estimates can be Kalman filtered to reject measurements which have a large change in magnitude or represent a large change in breathing rate. The measurements may also be fused with measurements from another sensor. | 11-25-2010 |