| Patent application number | Description | Published |
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| 20100055142 | Carrier Neutralization/Modification in Antimicrobial Compositions, Articles and Methods - A method of treating a substrate having a charge bias with at least one antimicrobial agent to modify the release properties of the antimicrobial agent with respect to the substrate, the method includes eliminating, mitigating, or modifying the charge bias of the substrate by applying at least one first agent to the substrate, and applying the at least one antimicrobial agent to the substrate. Related articles are also described. | 03-04-2010 |
| 20100055158 | Environmentally Activated Compositions, Articles and Methods - An article includes a film layer; at least one layer of adhesive on at least one side of the film layer; a patch or strip comprising at least one antimicrobial agent, the patch or strip disposed on the same side of the film layer as the at least one layer of adhesive; and a relatively non-flexible sheet releasably attached to the side of the film layer opposite to the patch or strip. Alternatively, an article includes a film layer; a collagen layer; and a biodegradable hydrogel layer comprising PHMB; wherein the biodegradable hydrogel layer comprising PHMB is disposed between the film layer and the collagen layer | 03-04-2010 |
| 20100055437 | ANTI-MICROBIAL FIBERS AND RELATED ARTICLES AND METHODS - An antimicrobial fiber is described including: an inner layer and an outer layer; wherein the inner layer and the outer layer comprise at least one of the following characteristics: (I) the inner layer and the outer layer comprise of different concentrations, or different release rates, of at least one antimicrobial agent; and (II) the inner layer and the outer layer comprise different antimicrobial agents. An alternative antimicrobial fiber includes an antimicrobial agent compounded or combined with a dissolvable substance to promote release or binding of the antimicrobial agent. Related articles are also described. | 03-04-2010 |
| 20100081996 | Transparent Catheter Securement System - A securement device for securing a catheter to a patient is provided. The securement device includes a base including a support member and at least one securement arm extending away from the support member. The support member defines a cradle portion, the cradle portion of the support member being configured to receive at least a portion of a catheter. The at least one securement arm being movable over the cradle portion to a position to secure a catheter within the cradle portion. The securement device further includes a cover member configured to be received over the base and dimensioned to secure the base to a patient. | 04-01-2010 |
| 20100179493 | Canister for Receiving Wound Exudate in a Negative Pressure Therapy System - A system to promote the healing of an exuding wound includes a wound dressing, a subatmospheric pressure mechanism, and a collection canister. The wound dressing is dimensioned for positioning relative to a wound bed of a subject. The subatmospheric pressure mechanism includes a control unit disposed within a housing. The control unit includes a vacuum source associated with a vacuum port. The collection canister has an interior wall which defines an internal chamber. The internal chamber is in fluid communication with the vacuum source of the subatmospheric pressure mechanism through the vacuum port and with the wound dressing for collecting exudates removed for the wound bed under influence of the vacuum source. The canister including a baffle mechanism disposed within the internal chamber for dampening the movement of the collected exudates. | 07-15-2010 |
| 20100260824 | Antimicrobial Foam Compositions, Articles and Methods - Articles may be formed including: at least one layer of foam, the foam layer and at least one antimicrobial agent associated with foam layer, the antimicrobial agent including PHMB, PEHMB, or derivatives thereof; at least one non-adherent layer disposed on at least a portion of the foam layer, the non-adherent layer being permeable to moisture; and a film disposed on at least another portion of the foam layer, the film being breathable to allow escape of moisture, but substantially impermeable to bacteria. Another article may include at least one layer of foam, the foam having pores of different sizes, at least some of the pores at least partially filled with at least one elutable antimicrobial agent, the pores of different sizes forming a gradient with the foam layer. Yet another article may include a foam matrix and a plurality of dissolvable members disposed with the foam matrix, at least one antimicrobial agents associated with the dissolvable members such that upon dissolution thereof the antimicrobial agent is eluted and pores or voids are created in the foam matrix. Wound dressings formed from the above articles are also described. | 10-14-2010 |
| 20100324516 | Apparatus for Vacuum Bridging and/or Exudate Collection - An apparatus for promoting the healing of an exuding wound includes a cover layer for positioning over a wound to define a reservoir over the wound. An exudate conduit having a fibrous core includes a plurality of fibers communicates with the reservoir for wicking fluids away from the wound. | 12-23-2010 |
| Patent application number | Description | Published |
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| 20080260724 | Drug Induced Exposure Of The Fungal Pro-Inflammatory Molecule Beta-Glucan - Methods and reagents for screening for anti-microbial agents are provided. Diagnostic tools for assessing treatment of fungal infections are provided. Antimicrobial substances including substances useful for the treatment of fungal infections are provided. In some embodiments, the substances have antigen unmasking activity. In some embodiments the substances have fungicidal activity and surface antigen unmasking activity. | 10-23-2008 |
| 20090288222 | Transgenic plants overexpressing a plant vacuolar Pyrophosphatase - Transgenic plants are described which are engineered to overexpress vacuolar H | 11-19-2009 |
| 20100215708 | COATING OF DEVICES WITH EFFECTOR COMPOUNDS - This invention is directed to substrates, materials and devices coated with a gel, foam, film, particle or composition comprising a polymei solvent and effector compounds attached thereto, processes of producing the same, and methods of use thereof, of in, inter-alia, biological applications, including preventing infection and the treatment of various diseases. | 08-26-2010 |
| 20110045049 | IMMUNOMODULATING COMPOSITIONS AND METHODS OF USE - This invention is directed to β-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The β-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety. | 02-24-2011 |
| 20110177532 | IMMUNOMODULATING COMPOSITIONS AND METHODS OF USE THEREOF - The invention is directed to β1-6 glucans, compositions, diagnostic kits, and devices comprising the same, and methods of use thereof in modulating immune response and treating, delaying progression of, reducing the incidence or severity of cancer, infection, inflammation, and autoimmune diseases. The β1-6 glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety. The β1-6 glucans of certain embodiments of the invention recruit immunoglobulin G antibodies to mediate complement and neutrophil killing. The conjugated β1-6 glucans of certain embodiments of the invention are targeted to cells to stimulate the immune response at the target location by activating complement-mediated lysis and recruitment of neutrophils. | 07-21-2011 |
| Patent application number | Description | Published |
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| 20090034927 | PHOTONIC CRYSTAL FIBERS AND MEDICAL SYSTEMS INCLUDING PHOTONIC CRYSTAL FIBERS - In general, in one aspect, the disclosure features a system that includes a flexible waveguide having a hollow core extending along a waveguide axis and a region surrounding the core, the region being configured to, guide radiation from the CO | 02-05-2009 |
| 20090097805 | THERMAL SENSING FIBER DEVICES - There is provided a thermal sensing fiber including a semiconducting element having a fiber length and characterized by a bandgap energy corresponding to a selected operational temperature range for the fiber in which there can be produced a change in thermally-excited electronic charge carrier population in the semiconducting element in response to a temperature change in the selected temperature range. At least one pair of conducting electrodes is provided in contact with the semiconducting element along the fiber length, and an insulator is provided along the fiber length. | 04-16-2009 |
| 20090169158 | Thermal sensing fiber devices - There is provided a feedback-controlled self-heat-monitoring fiber, including an insulator having a fiber length with at least one metal-semiconductor-metal thermal sensing element along the fiber length and disposed at a position in a cross section of the fiber for sensing changes in fiber temperature. An electronic circuit is connected to the thermal sensing element for indicating changes in fiber temperature. A controller is connected for controlling optical transmission through an optical transmission element, that is disposed along the fiber length, in response to indications of changes in fiber temperature. | 07-02-2009 |
| 20090207867 | SURFACE-EMITTING FIBER LASER - In one aspect, the disclosure features an article, including a fiber waveguide extending along a waveguide axis, the fiber waveguide including a core extending along the waveguide axis and a confinement region surrounding the core. The confinement region is configured to guide radiation at a first wavelength, λ | 08-20-2009 |
| 20100079853 | OPTIMIZED CASCADED RAMAN FIBER-BASED LASER SOURCE FOR HIGH EFFICIENCY MID-INFRARED SPECTRAL GENERATION - A laser structure is provided that includes a pulsed source producing a pulsed signal having a low spontaneous noise component to its spectral output and a pulse-shape that is optimally flat. Also, the laser structure includes one or more optical fiber structures receiving the pulsed signal and performing Raman amplification. The pulsed signal is used to excite in the one or more optical fiber structures possessing normal chromatic dispersion, which acts as a nonlinear system for efficient mid-infrared spectral generation. | 04-01-2010 |
| 20100316088 | Thermal Sensing Fiber Devices - There is provided a thermal sensing fiber grid, including a plurality of rows and columns of thermal sensing fibers, each of which includes a semiconducting element that has a fiber length and that is characterized by a bandgap energy corresponding to a selected operational temperature range of the fiber in which there can be produced a change in thermally-excited electronic charge carrier population in the semiconducting element in response to a temperature change in the selected temperature range. There is included at least one pair of conducting electrodes in contact with the semiconducting element along the fiber length, and an insulator along the fiber length. An electronic circuit is provided for and connected to each thermal sensing fiber for producing an indication of thermal sensing fiber grid coordinates of a change in ambient temperature. | 12-16-2010 |
| 20110097581 | IN-FIBER FILAMENT PRODUCTION - In a fiber there is provided a fiber matrix material having a fiber length; and an array of isolated in-fiber filaments that extend the fiber length. The in-fiber filaments are disposed at a radius in a cross section of the fiber that is a location of a continuous filament material layer in a drawing preform of the fiber. As a result, there is provided a fiber matrix material having a fiber length; and a plurality of isolated fiber elements that are disposed in the fiber matrix, extending the fiber length, where the plurality is of a number greater than a number of isolated domains in a drawing preform of the fiber. | 04-28-2011 |
| 20110251603 | PHOTONIC CRYSTAL FIBERS AND MEDICAL SYSTEMS INCLUDING PHOTONIC CRYSTAL FIBERS - In general, in one aspect, the disclosure features a system that includes a flexible waveguide having a hollow core extending along a waveguide axis and a region surrounding the core, the region being configured to guide radiation from the CO | 10-13-2011 |
