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Ferrigno
Federica Ferrigno, Rome IT
| Patent application number | Description | Published |
|---|---|---|
| 20090048228 | Heterocycle Derivatives As Histone Deacetylase (Hdac) Inhibitors - The present invention relates to compounds of formula I: | 02-19-2009 |
| 20100261709 | PYRIDAZINONE DERIVATIVES AS PARP INHIBITORS - The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of poly(ADP-ribose)polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischaemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes mellitus, neurodegenerative diseases, retroviral infections, retinaldamage, skin senescence and UV-induced skin damage, and as chemo- or radiosensitizers for cancer treatment. | 10-14-2010 |
Federica Ferrigno, Pomezia IT
| Patent application number | Description | Published |
|---|---|---|
| 20090076101 | Thiophene and Thiazole Substituted Trifluoroethanone Derivatives as Histone Deacetylase (HDAC) Inhibitors - The present invention relates to compounds of formula (I), and pharmaceutically acceptable salts and tautomers thereof. Compounds of the present invention are inhibitors of histone deacetylase (HDAC) and are useful for treating cellular proliferative diseases, including cancer. They are also useful for treating neurodegenerative diseases, mental retardation, 10 schizophrenia, inflammatory diseases, restenosis, immune disorders, diabetes, cardiovascular disorders and asthma. | 03-19-2009 |
| 20090156591 | Thiophene and Thiazole Substituted trifluoroethanone Derivatives as Histone Deacetylase (Hdac) Inhibitors - The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt or stereoisomer thereof. The compounds of the present invention are inhibitors of histone deacetylase (HDAC) and are useful for treating cellular proliferative diseases, including cancer. Further, the compounds of the present invention are useful for treating neurodegenerative diseases, schizophrenia and stroke among other diseases. | 06-18-2009 |
| 20090176765 | Pyridinone and Pyridazinone Derivatives as Inhibitors of Poly (Adp-Ribose) Polymerase (Parp) - The present invention relates to compounds of formula I: | 07-09-2009 |
| 20090275619 | Amide Substituted Indazole and Benzotriazole Derivatives as Poly(ADP-Ribose)Polymerase (PARP) Inhibitors - The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of poly (ADP-ribose) polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes, neurodegenerative diseases, retroviral infection, retinal damage or skin senescence and UV-induced skin damage, and as chemo- or radiosensitizers for cancer treatment. | 11-05-2009 |
Francesco Ferrigno, Milan IT
| Patent application number | Description | Published |
|---|---|---|
| 20090019455 | Messaging interface system for serving a message to a target system - A system is disclosed for serving a message to a target system. A database message is converted to a common data model to conform to at least two systems and an architecture of the target system. The common data model is transformed into a specified data type of the architecture of the target system. Calls are managed using specified functions available through an application programming interface offered by the architecture of the target system. Functions of the application programming interface are invoked to implement a target message in the architecture of the target system. The message is written to the target system. | 01-15-2009 |
Rosaria Ferrigno, Villeurbanne FR
| Patent application number | Description | Published |
|---|---|---|
| 20090311666 | MICROFLUIDIC DEVICE FOR CRYSTALLIZATION AND CRYSTALLOGRAPHIC ANALYSIS OF MOLECULES - The present invention relates to a microfluidic device comprising at least one crystallization chamber adapted for comprising a solution in which at least one compound is present according to a concentration gradient, and wherein the geometry of said crystallization chamber allows for convection phenomena to be limited. The invention also relates to the use of said device, in particular for crystallization by counter diffusion and to a crystallization method. | 12-17-2009 |
Stephen Joseph Ferrigno, Cincinnati, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20080237403 | METAL INJECTION MOLDING PROCESS FOR BIMETALLIC APPLICATIONS AND AIRFOIL - A method of producing an airfoil including the steps of providing a first preform having a metallic powder of a first alloy, the first preform defining an airfoil body having curved pressure and suction sides. A tip cap is disposed between the pressure and suction sides of the airfoil at a radially outer end of the airfoil body. A partial height squealer tip extends radially outwards from the tip cap to provide a second preform that is a metallic powder of a second alloy different from the first alloy. The tip cap is formed in the shape of an extension of the squealer tip. The first and second preforms are sintered to consolidate the metal powders. An airfoil according to the method is also disclosed. | 10-02-2008 |
| 20110005075 | SOLID STATE RESISTANCE WELDING FOR AIRFOIL REPAIR AND MANUFACTURE - A method for bonding airfoil sections includes aligning upper and stub airfoil sections having upper airfoil pressure and suction sides and stub airfoil pressure and suction sides respectively, pressing together upper and stub airfoil cross sections at upper and stub airfoil distal ends of the upper and stub airfoil sections respectively, and then resistance welding, preferably solid state resistance welding, the upper and stub airfoil sections together along the upper and stub airfoil cross sections by passing electrical current across the upper and stub airfoil cross sections. The upper and stub airfoil sections may be clamped between pressure and suction side upper airfoil electrodes and between the stub airfoil pressure and suction sides respectively. The method may be performed while the stub airfoil section is attached to an airfoil carrier such as a rotor disk rim, a gas turbine engine drum, or a gas turbine engine blade platform. | 01-13-2011 |