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| 20080213308 | Imidazoquinoline Compounds - The invention provides novel compositions comprising imidazoquinoline compounds. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are novel compositions and methods of administering the compositions in combination with (an)other agent(s). | 09-04-2008 |
| 20090155306 | Pamps, pathogen associated molecular patterns - A method for identifying a polypeptide which acts as an adjuvant in a host organism. The invention further provides adjuvant compositions comprising said polypeptides and optionally further comprising an antigen. | 06-18-2009 |
| 20090311288 | IMIDAZOQUINOXALINE COMPOUNDS AS IMMUNOMODULATORS - The invention proyides novel compositions comprising imidazoquinoxaline compounds of formula (I) and analogs thereof. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are novel compositions and methods of administering the compositions in combination with (an) other agent (s). | 12-17-2009 |
| 20110104186 | Small molecule immunopotentiators and assays for their detection - The invention provides immunostimulatory compositions comprising a small molecule immuno-potentiator (SMIP) compound and methods of administration thereof. Also provided are methods of administering a SMIP compound in an effective amount to enhance the immune response of a subject to an antigen. Further provided are novel compositions and methods of administering SMIP compounds alone or in combination with another agent for the treatment of cancer, infectious diseases and/or allergies/asthma. In a further aspect, the invention relates generally to methods of screening for small molecule immuno-modulatory compositions. | 05-05-2011 |
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| 20090187028 | Process for preparing Chiral Dipeptidyl Peptidase -IV Inhibitor Intermediates - A novel process is provided for the preparation of chiral trans-2,3-disubstituted 5-oxotetrahydropyrans of structural formula (I): | 07-23-2009 |
| 20100204486 | Process for the Synthesis of (+)and (-)-1 Aryl-3-Azabicyclo(3.1.0) Hexanes - The present invention is concerned with novel processes for the preparation of (+)-1-aryl-3-azabicyclo[3,10]hexanes or a pharmaceutically acceptable salt thereof, and (−)-1-aryl-3-azabicyclo[3,10]hexanes or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be useful for treating e.g., pain, depression, anxiety disorders, eating disorders and urinary incontinence. | 08-12-2010 |
| 20100222394 | METHOD FOR PRODUCING PYRAZOL-3-YL-BENZAMIDE DERIVATIVE - The present invention provides a more efficient industrial method for producing a pyrazol-3-yl-benzamide derivative expressed by a formula useful as medicine: | 09-02-2010 |
| 20100298574 | Process For The Synthesis Of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane - The present invention is concerned with novel processes for the preparation of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be useful for treating e.g., depression, anxiety disorders, eating disorders and urinary incontinence. | 11-25-2010 |
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| 20090123979 | Methods of reducing the inhibitory effect of a tannin on the enzymatic hydrolysis of cellulosic material - The present invention relates to methods of producing a cellulosic material reduced in a tannin, comprising treating the cellulosic material with an effective amount of a tannase to reduce the inhibitory effect of the tannin on enzymatically saccharifying the cellulosic material. The present invention also relates to methods of saccharifying a cellulosic material, comprising: treating the cellulosic material with an effective amount of a tannase and an effective amount of a cellulolytic enzyme composition, wherein the treating of the cellulosic material with the tannase reduces the inhibitory effect of a tannin on enzymatically saccharifying the cellulosic material with the cellulolytic enzyme composition. The present invention also relates to methods of producing a fermentation product, comprising: (a) saccharifying a cellulosic material with an effective amount of a cellulolytic enzyme composition; (b) fermenting the saccharified cellulosic material of step (a) with one or more fermenting microorganisms to produce a fermentation product; and (c) recovering the fermentation product, wherein the cellulosic material is treated with an effective amount of a tannase to reduce the inhibitory effect of a tannin on enzymatically saccharifying the cellulosic material. | 05-14-2009 |
| 20090130707 | Methods of reducing the inhibitory effect of a redox active metal ion on the enzymatic hydrolysis of cellulosic material - The present invention relates to methods of producing a cellulosic material reduced in a redox active metal cation having a redox potential (E | 05-21-2009 |
| 20090215128 | Methods for degrading lignocellulosic materials - The present invention relates to methods for degrading a lignocellulosic material, comprising: treating the lignocellulosic material with an effective amount of one or more cellulolytic enzymes in the presence of at least one surfactant selected from the group consisting of a secondary alcohol ethoxylate, fatty alcohol ethoxylate, nonylphenol ethoxylate, tridecyl ethoxylate, and polyoxyethylene ether, wherein the presence of the surfactant increases the degradation of lignocellulosic material compared to the absence of the surfactant. The present invention also relates to methods for producing an organic substance, comprising: (a) saccharifying a lignocellulosic material with an effective amount of one or more cellulolytic enzymes in the presence of at least one surfactant selected from the group consisting of a secondary alcohol ethoxylate, fatty alcohol ethoxylate, nonylphenol ethoxylate, tridecyl ethoxylate, and polyoxyethylene ether, wherein the presence of the surfactant increases the degradation of lignocellulosic material compared to the absence of the surfactant; (b) fermenting the saccharified lignocellulosic material of step (a) with one or more fermenting microorganisms; and (c) recovering the organic substance from the fermentation. | 08-27-2009 |
| 20100159509 | Methods for increasing enzymatic hydrolysis of cellulosic material in the presence of a peroxidase - The present invention relates to methods for increasing hydrolysis of a cellulosic material, comprising: hydrolyzing the cellulosic material with an enzyme composition in the presence of a polypeptide having peroxidase activity. | 06-24-2010 |
| 20100159535 | METHODS FOR INCREASING HYDROLYSIS OF CELLULOSIC MATERIAL - The present invention relates to methods for pretreating a cellulosic material, methods for degrading or converting a cellulosic material, methods for producing a fermentation product, and methods of fermenting a cellulosic material under anaerobic conditions. | 06-24-2010 |
| 20100273734 | Derivatives of Hyaluronic Acids - The present invention relates to methods for preparing a derivative of a hyaluronic acid, comprising: (a) mixing a liquid solution comprising the hyaluronic acid and a diamine, a polyamine, or a combination thereof, at a pH suitable to form an imine; (b) reducing the imine to an amine with a reductant at a pH suitable to produce the derivative of the hyaluronic acid; and (c) recovering the derivative of the hyaluronic acid. The present invention also relates to isolated derivatives of a hyaluronic acid, comprising the hyaluronic acid and a diamine, a polyamine, or a combination thereof. | 10-28-2010 |
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| 20100226931 | Compounds for immunopotentiation - Methods of stimulating an immune response and treating patients responsive thereto with 3,4-di(1H-indol-3-yl)-1H-pyrrole-2,5-diones, staurosporine analogs, derivatized pyridazines, chromen-4-ones, indolinones, quinazolines, nucleoside analogs, and other small molecules are disclosed. In a preferred embodiment benzopyrimidine derivatives such as ZD-6474, MLN-518, lapatinib, gefitinib or erlotinib are used. | 09-09-2010 |
| 20110217323 | IMIDAZOQUINOLINE COMPOUNDS - The invention provides novel compositions comprising imidazoquinoline compounds. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are novel compositions and methods of administering the compositions in combination with (an) other agent(s). | 09-08-2011 |
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| 20090321318 | Hydrocarbon Dehydrogenation with Zirconia - A method for obtaining an olefin is disclosed, the method comprising subjecting a paraffin to dehydrogenation in the absence of oxygen and in the presence of a catalyst comprising a crystalline substrate, to obtain an olefin. The catalyst includes an inert stabilizing agent for maintaining the catalyst crystal structure. The catalyst may be regenerated by being subjected, in air, to a temperature between about 550° C. and about 750° C., for a period of time between about 15 minutes and about 4 hours. | 12-31-2009 |
| 20090325784 | Hydrocarbon Dehydrogenation with Zirconia - A method for obtaining an olefin is disclosed, the method comprising subjecting a paraffin to dehydrogenation in the absence of oxygen and in the presence of a catalyst comprising a crystalline substrate, to obtain an olefin. The catalyst includes an inert stabilizing agent for maintaining the catalyst crystal structure. The catalyst may be regenerated by being subjected, in air, to a temperature between about 550° C. and about 750° C, for a period of time between about 15 minutes and about 4 hours. | 12-31-2009 |
| 20090325791 | Hydrocarbon Dehydrogenation with Zirconia - A method for obtaining an olefin is disclosed, the method comprising subjecting a paraffin to dehydrogenation in the absence of oxygen and in the presence of a catalyst comprising a crystalline substrate, to obtain an olefin. The catalyst includes an inert stabilizing agent for maintaining the catalyst crystal structure. The catalyst may be regenerated by being subjected, in air, to a temperature between about 550° C. and about 750° C., for a period of time between about 15 minutes and about 4 hours. | 12-31-2009 |
| 20110245067 | SURFACE-MODIFIED ZEOLITES AND METHODS FOR PREPARING THE SAME - Surface-modified zeolites and methods for preparing surface-modified zeolites are provided. A hybrid polymer formed from a silicon alkoxide and a metal alkoxide, a co-monomer, or both, is contacted with a zeolite suspension. The zeolite suspension comprises a sodium-, an ammonium-, or a hydrogen-form zeolite and a solvent. The hybrid polymer and zeolite suspension are contacted under conditions sufficient to deposit hybrid polymer on external surfaces of the zeolite to form a treated zeolite. Solvent is removed therefrom. The treated zeolite is dried and calcinated to form a dried and calcinated treated zeolite. Forming of the zeolite suspension and the contacting, removing, drying, and calcinating steps are provided in one selectivation sequence to produce a surface-modified zeolite from the ammonium-form zeolite and the hydrogen-form zeolite. If the dried and calcinated treated zeolite is a sodium-form zeolite, the sodium is exchanged with ammonium and then additionally dried and calcinated. | 10-06-2011 |
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| 20080242959 | Fingertip Oximeter and a Method for Observing a Measurement Result Thereon - There is provided a fingertip oximeter that has a plurality of display modes which are presented sequentially in a circulating way, allowing users to easily observe a measurement result from any of surrounding directions. The present invention makes users to be able to observe a measurement result of the fingertip oximeter from any of surrounding directions, without the need of bending his/her finger. Thus, any partial occlusion of the arterial blood capillary can be avoided, so that strength of the pulse will not decrease, and strength of the signal will not be affected. As a result, the precision of the measurement is improved. | 10-02-2008 |
| 20080306395 | Portable Electrocardiograph - A portable electrocardiograph comprising a housing and a second electrode which is provided on one end of the housing, characterized in that a clamping cover which tends to close automatically is provided on the other end of the housing; an oval finger hole is provided between the clamping cover and the housing; the lower half of the inner wall of the finger hole is defined on the housing; the lower half of the inner wall is provided with a first electrode; and the upper half of the inner wall of the finger hole is provided on the clamping cover, such that the present invention provides the portable electrocardiograph of simple structure, convenient use, and high reliability for heart disease sufferers. | 12-11-2008 |
| 20110190602 | METHOD FOR MEASURING BLOOD OXYGEN AT A FINGER AND FINGER-CLIPPED OXIMETER - The present invention provides a method for measuring blood oxygen at a finger, comprising the following steps: | 08-04-2011 |
