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Fehr, US

Adrian Fehr, Los Altos, CA US

Patent application numberDescriptionPublished
20100009872Single molecule loading methods and compositions - Methods, compositions and arrays for non-random loading of single analyte molecules into array structures are provided.01-14-2010
20100092960Helicase-assisted sequencing with molecular beacons - Provided are compositions that include an at least partially single-stranded nucleic acid, at least one first molecular beacon, and an enzyme comprising a helicase activity, which enzyme is capable of removing the first molecular beacon from the single-stranded nucleic acid wherein the first molecular beacon is hybridized to a first complementary subsequence of the nucleic acid. Also provided are methods of determining the sequence of a template nucleic acid that include removing molecular beacons that are hybridized to the template from the template in a sequential manner using an enzyme that exhibits a helicase activity, detecting a sequence of fluorescent signals that is produced by the removal of a molecular beacons, and converting the sequence of fluorescent signals into nucleotide sequence information. Sequencing systems in which compositions and methods of the invention can be used are also provided.04-15-2010
20100331194NANOPORE SEQUENCING DEVICES AND METHODS - The invention relates to devices and methods for nanopore sequencing. The invention includes arrays of nanopores having incorporated electronic circuits, for example, in CMOS. In some cases, the arrays of nanopores comprise resistive openings for isolating the electronic signals for improved sequencing. Methods for controlling translocation of through the nanopore are disclosed.12-30-2010
20120014837ILLUMINATION OF INTEGRATED ANALYTICAL SYSTEMS - An analytical device including an optically opaque cladding, a sequencing layer including a substrate disposed below the cladding, and a waveguide assembly for receiving optical illumination and introducing illumination into the device. The illumination may be received from a top, a side edge, and a bottom of the device. The waveguide assembly may include a nanoscale aperture disposed in the substrate and extending through the cladding. The aperture defines a reaction cell for receiving a set of reactants. In various aspects, the device includes a sensor element and the illumination pathway is through the sensor element. Waveguides and illumination devices, such as plasmonic illumination devices, are also disclosed. Methods for forming and operating the devices are also disclosed.01-19-2012
20120021525OPTICS COLLECTION AND DETECTION SYSTEM AND METHOD - Optics collection and detection systems are provided for measuring optical signals from an array of optical sources over time. Methods of using the optics collection and detection systems are also described.01-26-2012

Cornelius Fehr, Millersburg, OH US

Patent application numberDescriptionPublished
20080236573CAMPFIRE CHIP BURNER - A campfire burner is a self-container device that holds loosely-packed hardwood chips that function as the main fuel for the burner. The chip container is fabricated from a flammable material so that the entire burner burns to ash when used. A chimney and air vents are provided to direct air to the fuel. A fire starter may be provided to allow the camper to start the fire with a single match.10-02-2008

Daniel Fehr US

Patent application numberDescriptionPublished
20110301240CONDITIONING COMPOSITION - The present invention is directed to a composition for the conditioning of a dental mineralized surface and/or a dental implant and/or for increasing the hydrophilicity of a dental implant having a metal containing surface. The composition comprises EDTA in a concentration of 21-55% by weight and having a pH of 9.0 or above. The high pH of the composition allows more EDTA to be dissolved and the composition is useful for the conditioning of mineralized dental surfaces and/or surfaces of dental implants. The composition of the invention may thus be used for the conditioning of mineralized dental surfaces and dental implant surfaces in order to remove e.g. biofilm, debris, bacteria, bacterial toxins etc and/or for increasing the hydrophilicity of an implant having a metallic surface. The invention is also directed to a kit comprising the composition of the invention and a device to apply the composition to a surface in need of conditioning.12-08-2011

Dave Fehr, Morton, IL US

Patent application numberDescriptionPublished
20110296770STRUCTURAL COLUMN WITH FOOTING STILIT - A structural column assembly of the type used for erecting building structures and the like is bedded in a concrete footing formed in situ in an earthen hole. The column assembly includes a post whose bottom end is suspended above a floor of the hole by a stilt. The stilt includes a plurality of legs which extend from the post's bottom end and grip the hole floor through a plurality of cleats. The cleats help stabilize the column assembly during the concrete pour operation so that it does not shift out of position. The stilt legs are provided with a base pad, which is set below the bottom end of the post at a predetermined distance so that the concrete footing can be poured in a single operation immediately after the hole is formed. The stilt can accommodate posts made from wood, pre-cast concrete or any other known construction material. The stilts can be manufactured from formed flat steel or commercially available angle iron and channel stock.12-08-2011

David A. Fehr, Morton, IL US

Patent application numberDescriptionPublished
20120043767SELF-LATCHING AND SELF-LOCKING LATCH SYSTEM FOR SLIDING DOOR PANELS - A sliding door latching and locking system is disclosed which includes a latch assembly, a lift rod assembly, and a retainer assembly, among other things. In some embodiments, the latch assembly includes a support member mounted in a movable body and a latching arm pivotally mounted to the support member having a distal end thereof extending outside of the periphery of the movable body, wherein the distal end includes an engagement facilitating portion with a sloped outer surface for contacting an interlocking member.02-23-2012

Gary Fehr, Morris, MN US

Patent application numberDescriptionPublished
20080307761Silage pile defacer - A silage pile defacer includes a frame having a rear end and a front end. A transverse beam carrying a plurality of downwardly projecting tines is coupled to the front end of the frame. A quick connect coupler is mounted to the rear end of the frame for mounting the defacer to a quick hitch coupler on the lift arm mechanism of a tractor. The tines are oriented at an acute angle relative to the frame, allowing the tines to be generally perpendicular to the ground when the defacer is elevated above a silage pile. The tines of the defacer skive off a face layer of the silage pile when the defacer is lowered to the ground by the tractor lift arm mechanism.12-18-2008
20100005770Silage pile defacer - A silage pile defacer includes a frame having a rear end and a front end. A transverse beam carrying a plurality of downwardly projecting tines is coupled to the front end of the frame. A quick connect coupler is mounted to the rear end of the frame for mounting the defacer to a quick hitch coupler on the lift arm mechanism of a tractor. The tines are oriented at an angle relative to the frame, allowing the tines to be generally vertically oriented relative to the ground when the defacer is elevated above a silage pile. The tines of the defacer are configured to contact the silage pile and to skive off a face layer of the silage pile when the defacer is lowered to the ground by the tractor lift arm mechanism.01-14-2010
20120001004Silage pile defacer - A silage pile defacer includes a frame having a rear end and a front end. A transverse beam carrying a plurality of downwardly projecting tines is coupled to the front end of the frame. A quick connect coupler is mounted to the rear end of the frame for mounting the defacer to a quick hitch coupler on the lift arm mechanism of a tractor. The tines are oriented at an angle relative to the frame, allowing the tines to be generally vertically oriented relative to the ground when the defacer is elevated above a silage pile. The tines of the defacer are configured to contact the silage pile and to skive off a face layer of the silage pile when the defacer is lowered to the ground by the tractor lift arm mechanism.01-05-2012

Patent applications by Gary Fehr, Morris, MN US

Jean-Noel Fehr US

Patent application numberDescriptionPublished
20090044629METHOD OF MONITORING PRESSURE OF A GAS SPECIES AND APPARATUS TO DO SO - A method of monitoring pressure of a gas species up to at most a predetermined maximum pressure value is disclosed. The method includes exposing the gas species to transmission of laser light, periodically modulating the wavelength of the laser light over a wavelength band including at least one absorption line of the gas species, optoelectrically converting the transmitted laser light, thereby generating an electric output signal, performing at least one of first filtering the electric output signal with a filter characteristic having a lower cut-off frequency not lower than a transition frequency and of second filtering the electric output signal with a bandpass filter characteristic having an upper cut-off frequency not higher than the transition frequency and a lower cut-off frequency above the modulation frequency of the periodic wavelength modulation. The output of at least one of the filterings is evaluated as a pressure indicative signal.02-19-2009
20100005893METHOD OF MONITORING PRESSURE OF A GAS SPECIES AND APPARATUS TO DO SO - A method of monitoring pressure of a gas species up to at most a predetermined maximum pressure value is disclosed. The method includes exposing the gas species to transmission of laser light, periodically modulating the wavelength of the laser light over a wavelength band including at least one absorption line of the gas species, optoelectrically converting the transmitted laser light, thereby generating an electric output signal, performing at least one of first filtering the electric output signal with a filter characteristic having a lower cut-off frequency not lower than a transition frequency and of second filtering the electric output signal with a bandpass filter characteristic having an upper cut-off frequency not higher than the transition frequency and a lower cut-off frequency above the modulation frequency of the periodic wavelength modulation. The output of at least one of the filterings is evaluated as a pressure indicative signal.01-14-2010

Linda Fehr, Berwyn, IL US

Patent application numberDescriptionPublished
20080300777COMPUTER-CONTROLLED POWER WHEELCHAIR NAVIGATION SYSTEM - A wheelchair navigation system for a motorized wheelchair includes dual cameras, proximity sensors, microphones, and rotation sensors for the wheels. Small markers are placed on the walls of a location or room. The navigation system uses the proximity sensors, rotation sensors and cameras in conjunction with the specialized software to determine where objects or impediments are located in the room and thereby redirect the path of the wheelchair so as to avoid such objects. The wheelchair is walked through the marked location thereby ‘teaching’ various paths which are recorded in the computer and recalled later when the wheelchair is in use. The proximity sensor perform sensing operations during performance of the teaching functions for thereby permitting avoidance of wheelchair collision with obstacles during navigation of the wheelchair through a taught trajectory and allowing for close approach of the wheelchair to solid bodies present during performance of the teaching functions.12-04-2008

Marcus Fehr, Washington, DC US

Patent application numberDescriptionPublished
20100037329Development of sensitive fret sensors and methods of using the same - Intramolecular biosensors are disclosed, including PBP-based biosensors, comprising a ligand binding domain fused to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon binding ligand. At least one of the donor and fluorescent moieties may be internally fused to the biosensor such that both ends of the internally fused fluorophore are fixed. In addition, methods of improving the sensitivity of terminally fused biosensors are provided. The biosensors of the invention are useful for the detection and quantification of ligands in vivo and in culture.02-11-2010

Robert G. Fehr, Colfax, WI US

Patent application numberDescriptionPublished
20110247651Fabric Sweeper - The present invention is a device for use in cleaning a fabric surface of dust, dirt, pet hair and other debris present on the surface. The device includes a housing coupled to a base. The base is coupled to at least one movable cleaning member configured to engage a surface for picking up debris from the surface. The debris is deposited into a debris collection chamber by way of interaction with another portion of the device. The debris collection chamber is selectively emptiable by an operator thereof so that the device may be subsequently reused.10-13-2011

Robert L. Fehr, Lexington, KY US

Patent application numberDescriptionPublished
20120027388ADAPTIVE HEAT PUMP RESISTANCE HEAT CONTROLLER - An electrical heating apparatus includes a primary heating stage heat pump, a secondary heating stage resistance heating circuit having a plurality of heating elements, an adaptive resistance heat controller and a two-stage thermostat. The adaptive resistance heat controller is connected to the two-stage thermostat heat pump and resistance heating circuit. The adaptive resistance heat controller includes a duty cycle monitor that monitors the duty cycles of the thermostat primary and secondary stages. The controller selectively energizes one or more of the plurality of heating elements in response to changes in the duty cycles so as to provide adaptive heating control to meet actual heating demand while reducing overall peak energy consumption.02-02-2012