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Fantl

Steven A. Fantl, Colgate, WI US

Patent application numberDescriptionPublished
20100269550LOCK ASSEMBLY WITH REMOVABLE SHACKLE - A lock assembly includes a lock body with a shackle. The shackle has a leg. A locking element is disposed in the lock body and is selectively engageable to the shackle. A cam is disposed in the lock body and includes a locked position, an unlocked position and a shackle removal position. The leg includes a shackle removal recess that only partially extends circumferentially about an outer peripheral surface disposed about a longitudinal axis of the leg and is sized to receive the first locking element sufficiently to permit movement of the cam to the shackle removal position. The shackle is rotatable in the unlocked position to expose the shackle removal recess to the locking element.10-28-2010

Wendy Fantl, Emeryville, CA US

Patent application numberDescriptionPublished
20100249126PYRIMIDINE DERIVATIVES USED AS PI-3-KINASE INHIBITORS - Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases.09-30-2010

Wendy Fantl, San Francisco, CA US

Patent application numberDescriptionPublished
20100196368SUBSTITUTED BENZ-AZOLES AND METHODS OF THEIR USE AS INHIBITORS OF RAF KINASE - New substituted benz-azole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.08-05-2010
20100240542KITS FOR MULTIPARAMETRIC PHOSPHO ANALYSIS - As disclosed herein, the present invention provides for kits and a composition for diagnosis, prognosis, drug discovery, drug development, and patient stratification. The kits can comprise a plurality of binding elements for cell surface markers, and a plurality of binding elements for state-specific intracellular markers. The kits can further comprise a plurality of modulators directed for the particular cell function or signaling pathways. The kits can further include fixatives, permeabilizing agent, buffers, containers, instructions, and software for data analysis/compilation.09-23-2010