Fang-Yu
Fang-Yu Lee, Taichung City TW
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20140357688 | METHOD FOR INHIBITING EZH2 EXPRESSION IN BREAST CANCER CELLS - The present invention is directed to a method for inhibiting the overexpression of EZH2 in breast cancer cells. The method comprises administering to breast cancer cells an effective amount of YC-1 (3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole), YC-1-succinate (succinic acid mono-[5-(1-benzyl-1H-indazol-3-yl)-furan-2-ylmethyl]ester), or a pharmaceutically acceptable salt thereof. The present invention is also directed to treating breast cancer comprising administering to a subject an effective amount of YC-1-succinate. | 12-04-2014 |
Fang-Yu Lin, Taipei TW
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20130226549 | STRUCTURE-BASED FRAGMENT HOPPING FOR LEAD OPTIMIZATION AND IMPROVEMENT IN SYNTHETIC ACCESSIBILITY - The invention develops a computer-aided drug design method and system to optimize a lead through structure-based drug design with synthetic accessibility. In this invention, two systems of the structure-based lead optimization are developed and implemented: 1) LeadOp (“short for lead optimization”)—an algorithm that performs lead optimization through structure-based fragment hopping method; and 2) LeadOp+R (short for “lead optimization with synthetic accessibility based on chemical reaction route”)—an algorithm that performs lead optimization with synthetic accessibility. LeadOp algorithm provides users to optimize a lead compound with various combinations of fragments with stronger binding based on group efficiency, generating lead with stronger potency. Furthermore, LeadOp+R provides an advantage in the selection of the new fragment to be assembled, which was identified based on the group efficiency calculated in the active site and reaction rule. | 08-29-2013 |
Fang-Yu Lin, Taipei City TW
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20150229236 | ZERO-BIAS CAPACITIVE MICROMACHINED ULTRASONIC TRANSDUCERS AND FABRICATION METHOD THEREOF - The present invention provides a zero-bias capacitive micromachined ultrasonic transducer element, comprising: a substrate having a lower electrode formed therein; a membrane structure that structurally supports an upper electrode over the lower electrode, wherein the upper electrode has at least one protruding part thereunder; a cavity between the substrate and the membrane structure; and a polymeric material coated on an inner surface of the cavity. The fabrication method of the zero-bias capacitive micromachined ultrasonic transducer element is also provided. | 08-13-2015 |
Fang-Yu Liu, Union City, CA US
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20100022511 | Stabilized Atypical Antipsychotic Formulation - A pharmaceutical composition that contains an atypical antipsychotic drug and succinic acid, fumaric acid or a mixture of succinic acid and fumaric acid. | 01-28-2010 |
20110165238 | STABILIZED ATYPICAL ANTIPSYCHOTIC FORMULATION - A pharmaceutical composition that contains an atypical antipsychotic drug and succinic acid, fumaric acid or a mixture of succinic acid and fumaric acid. | 07-07-2011 |
20130273171 | ORAL FORMULATION FOR DEXLANSOPRAZOLE - A stable formulation of dexlansoprazole for treating a digestive disorder, and methods of manufacturing the same. | 10-17-2013 |
Fang-Yu Liu, Wuci Township TW
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20110304086 | SHADOW FRAME AND MANUFACTURING METHOD THEREOF - A shadow frame and a method of manufacturing the shadow frame are disclosed. The shadow frame is utilized in photoelectrical semiconductor manufacturing processes and is utilized for fixing a glass substrate by combing with a support base used to carry the glass substrate. The shadow frame has a plurality of frame components and welding parts, and the frame components are adjoined at the welding parts to form the shadow frame. The provided shadow frame and its manufacturing method are capable of improving the utility rate of the substrate used to manufacture the shadow frame, avoiding a waste of the substrate, and thereby capable of reducing the manufacturing cost. | 12-15-2011 |
Fang-Yu Lu, Sinwu Township TW
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20110125070 | Multifunction Recumbent Massage Bench - A multifunction massage bench includes a base frame and a bench mechanism. The bench mechanism is fixedly supported on the base frame and comprises a recumbent bench having a curved and convex top surface, a back massage assembly disposed under a first portion of the recumbent bench, a hip massage assembly disposed in a second portion of the recumbent bench, a foot massage assembly, and a head member. The back massage assembly comprises a first motor and rollers operatively actuated by the first motor so that the rollers repeatedly move upward and downward while rotating for performing a plurality of massage actions. The head member comprises a second motor for extending the head member outward to a predetermined distance so that the head of a person lying on the recumbent bench is disposed at an elevation slightly lower than that of the feet. | 05-26-2011 |
20130226051 | Massage Bench with Sliding Backrest - A massage bench is provided with a backrest assembly mounted on a support and including two parallel arc rails secured to the support, each rail including first teeth; and a sliding unit including an arc sliding backrest having two side first gears engaging the first teeth, and a sliding foot rest slidable about the first teeth; a drive assembly including a first motor, an output shaft operatively connected to the first gears, and a drive belt placed across the first motor and the output shaft so that the backrest and the foot rest move along the rails; and a massage assembly including a back massaging assembly in the backrest and including a moveable bracket, parallel second teeth secured to the backrest, second gears on either side of the bracket engaging the second teeth, and a second motor for driving rollers and the second gears; and a legs massaging assembly. | 08-29-2013 |
Fang-Yu Tu, Pingzhen City TW
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20150104028 | MEASURING DEVICE - A measuring device includes an audio collection module, an audio player module and a switch module. The audio player module electrically connects to the audio collection module, and the switch module electrically connects to the audio player module. The audio collection module collects sounds to generate an audio signal. The audio player module plays the audio signal. The switch module sets an enabling signal for controlling the audio player module. The enabling signal is set to be at either a first state or a second state different from the first state. When the enabling signal is at the first state, the audio player module plays the audio signal under a first output mode. When the enabling signal is at the second state, the audio player module plays the audio signal under a second output mode different from the first output mode. | 04-16-2015 |
20150105034 | WIRELESS TRANSMISSION DEVICE - A wireless transmission device includes an audio fetching module, a storage module, a processing module and a wireless transmission module. The processing module electrically connects to the audio fetching module and the storage module, and the wireless transmission module electrically connects to the processing module. The audio fetching module acquires an audio signal. The processing module either stores the audio signal in the storage module or reads out the stored audio signal when being enabled. The wireless transmission module enables the processing module and transmits the stored audio signal according to the transmission enabling signal. | 04-16-2015 |
Fang-Yu Tu, Taoyuan City TW
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20160030779 | MASK - A mask includes a cover body, at least one first fan, at least one second fan and an air filter. The cover body has at least one air inlet and at least one air outlet. The at least one air inlet and the at least one air outlet penetrate through the cover body. The at least one first fan is disposed on the cover body and matches the at least one air inlet. The at least one second fan is disposed on the cover body and matches the at least one air outlet. The air filter is disposed on the cover body and partially overlaps the at least one air inlet. | 02-04-2016 |