Patent application number | Description | Published |
20090065371 | Method and Apparatus for Metal Nanoparticle Electrocatalytic Amplification - The present invention includes methods, compositions and kits for analyzing a chemical analyte having an electrochemical cell connected to a measuring apparatus. The electrochemical cell contains a solution having one or more nanoparticles, one or more chemical analytes, an indicator. In addition, the electrochemical cell contains one or more electrodes in communication with the solution. One or more electrocatalytic properties are generated by the interaction of the one or more nanoparticles and the liquid sample and measured at the one or more electrodes. | 03-12-2009 |
20110111520 | LUMINESCENT NANOSTRUCTURED MATERIALS FOR USE IN ELECTROGENERATED CHEMILUMINESCENCE - A nanostructured particulate material, which includes a redox active luminescent organic and/or ionic compound, is provided herein. The nanostructured particulate material may be used for determining the presence of an analyte of interest in a sample by detecting the emitted electromagnetic radiation generated by exposing a reagent mixture, which includes the nanostructured material and the target analyte, to chemical or electrochemical energy. | 05-12-2011 |
20110120891 | METHOD AND APPARATUS FOR NANOPARTICLE ELECTROGENERATED CHEMILUMINESCENCE AMPLIFICATION - Methods, compositions and kits for analyzing a chemical analyte using an electrochemical cell connected to a measuring apparatus are provided. The electrochemical cell contains a solution having one or more conductive or redox active NPs (nanoparticles), one or more chemical analytes, and an indicator. In addition, the electrochemical cell contains one or more electrodes in communication with the solution. One or more catalytic ECL properties are generated by the interaction of the one or more conductive or redox active NPs and the liquid sample and measured at the one or more electrodes or with an optical detection system. | 05-26-2011 |
20120043225 | Method and Apparatus for Electrocatalytic Amplification on Pre-Oxidized Measuring Electrode - The present invention includes methods and compositions having at least one nanoparticle for analyzing a chemical analyte. The device includes an electrochemical cell connected to a measuring apparatus, wherein the electrochemical cell comprises a container and at least one electrode comprising a surface modification; a solution within the container comprising one or more chemical analytes and one or more metal nanoparticles in the solution, wherein one or more electrocatalytic properties are generated by the one or more metal nanoparticles at the at least one electrode and the contact of individual nanoparticles can be measured. | 02-23-2012 |
20130164530 | LUMINESCENT NANOSTRUCTURED MATERIALS FOR USE IN ELECTROGENERATED CHEMILUMINESCENCE - A nanostructured particulate material, which includes a redox active luminescent organic and/or ionic compound, is provided herein. The nanostructured particulate material may be used for determining the presence of an analyte of interest in a sample by detecting the emitted electromagnetic radiation generated by exposing a reagent mixture, which includes the nanostructured material and the target analyte, to chemical or electrochemical energy. | 06-27-2013 |
20140042037 | METHOD AND APPARATUS FOR NANOPARTICLE ELECTROGENERATED CHEMILUMINESCENCE AMPLIFICATION - Methods and devices for analyzing a chemical analyte using an electrochemical cell connected to a measuring apparatus are provided. The electrochemical cell contains a solution having one or more conductive or redox active NPs, one or more chemical analytes, and an indicator. In addition, the electrochemical cell contains one or more electrodes in communication with the solution. One or more catalytic ECL properties are generated by the interaction of the one or more conductive or redox active NPs and the liquid sample and measured at the one or more electrodes or with an optical detection system. | 02-13-2014 |
20140322538 | LUMINESCENT NANOSTRUCTURED MATERIALS FOR USE IN ELECTROGENERATED CHEMILUMINESCENCE - “A nanostructured particulates formed from a redox active, luminescent phenyl substituted polycyclic aromatic hydrocarbon are provided herein. The nanostructured particulates may be used for determining the presence of an analyte of interest in a sample by detecting the emitted electromagnetic radiation generated by exposing a reagent mixture, which includes the nanostructured particulates and the sample, to electrochemical energy.” | 10-30-2014 |
20150107657 | PRODUCTION OF THIN FILM SOLAR GRADE SILICON ON METALS BY ELECTRODEPOSITION FROM SILICON DIOXIDE IN A MOLTEN SALT - A method of producing a silicon film includes: forming a deposition composition comprising silicon dioxide dispersed in a molten salt; placing a metal substrate and a counter electrode in the composition; and passing a reducing current between the metal substrate and the counter electrode, wherein the reducing current causes reduction of silicon dioxide particles to form a silicon film on the metal substrate. | 04-23-2015 |
Patent application number | Description | Published |
20090113564 | Genetically Engineered and Phenotyped Mice and Stem Cell Clones for Producing the Same - The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides methods for using the mice, cells, polynucleotides, polypeptides and antibodies of the invention. | 04-30-2009 |
20090293137 | Novel Gene Disruptions, Compositions and Methods Relating Thereto - The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO218, PRO228, PRO271, PRO273, PRO295, PRO302, PRO305, PRO326, PRO386, PRO655, PRO162, PRO788, PRO792, PRO940, PRO941, PRO1004, PRO1012, PRO 1016, PRO474, PRO5238, PRO1069, PRO1111, PRO1113, PRO1130, PRO1195, PRO1271, PRO1865, PRO1879, PRO3446, PRO3543, PRO4329, PRO4352, PRO5733, PRO9859, PRO9864, PRO9904, PRO9907, PRO10013, PRO90948, PRO28694, PRO16089, PRO19563, PRO19675, PRO20084, PRO21434, PRO50332, PRO38465 or PRO346 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities. | 11-26-2009 |
20110173708 | NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO - The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO226, PRO257, PRO268, PRO290, PRO36006, PRO363, PRO365, PRO382, PRO444, PRO705, PRO1071, PRO1125, PRO1134, PRO1155, PRO1281, PRO1343, PRO1379, PRO1380, PRO1387, PRO1419, PRO1433, PRO1474, PRO1550, PRO1571, PRO1572, PRO1759, PRO1904, PRO35193, PRO4341, PRO4348, PRO4369, PRO4381, PRO4407, PRO4425, PRO4985, PRO4989, PRO5737, PRO5800, PRO5993, PRO6017, PRO7174, PRO9744, PRO9821, PRO9852, PRO9873, PRO10196, PRO34778, PRO20233, PRO21956, PRO57290, PRO38465, PRO38683 or PRO85161 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities. | 07-14-2011 |
20110182883 | NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO - The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO218, PRO228, PRO271, PRO273, PRO295, PRO302, PRO305, PRO326, PRO386, PRO655, PRO162, PRO788, PRO792, PRO940, PRO941, PRO1004, PRO1012, PRO1016, PRO474, PRO5238, PRO1069, PRO1111, PRO1113, PRO1130, PRO1195, PRO1271, PRO1865, PRO1879, PRO3446, PRO3543, PRO4329, PRO4352, PRO5733, PRO9859, PRO9864, PRO9904, PRO9907, PRO10013, PRO90948, PRO28694, PRO16089, PRO19563, PRO19675, PRO20084, PRO21434, PRO50332, PRO38465 or PRO346 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities. | 07-28-2011 |
20120272341 | NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO - The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO226, PRO257, PRO268, PRO290, PRO36006, PRO363, PRO365, PRO382, PRO444, PRO705, PRO1071, PRO1125, PRO1134, PRO1155, PRO1281, PRO1343, PRO1379, PRO1380, PRO1387, PRO1419, PRO1433, PRO1474, PRO1550, PRO1571, PRO1572, PRO1759, PRO1904, PRO35193, PRO4341, PRO4348, PRO4369, PRO4381, PRO4407, PRO4425, PRO4985, PRO4989, PRO5737, PRO5800, PRO5993, PRO6017, PRO7174, PRO9744, PRO9821, PRO9852, PRO9873, PRO10196, PRO34778, PRO20233, PRO21956, PRO57290, PRO38465, PRO38683 or PRO85161 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities. | 10-25-2012 |
Patent application number | Description | Published |
20100029958 | PROCESS FOR PRODUCING EPOXIDES - A process for producing epoxides, the process including: (a) feeding at least one aqueous alkali and at least one halohydrin to a reactive distillation column; (b) concurrently in the reactive distillation column: (i) reacting at least a portion of the halohydrin with the alkali to form an epoxide; and (ii) stripping water and the epoxide from a basic aqueous residue; (c) recovering the water and the epoxide from the reactive distillation column as an overheads fraction; and, (d) condensing and phase separating the overheads fraction at a temperature of 50° C. or less to form an organic overheads fraction including the epoxide and an aqueous overheads fraction including water. | 02-04-2010 |
20100029959 | PROCESS FOR PRODUCING EPOXIDES - A process for producing epoxides, the process including: (a) feeding at least one aqueous alkali and at least one halohydrin to a reactive distillation column, wherein the reactive distillation column includes a feed zone, a top zone disposed above the feed zone, and a bottom zone disposed below the feed zone; (b) concurrently in the reactive distillation column: (i) reacting at least a portion of the halohydrin with the alkali to form an epoxide; and (ii) stripping water and the epoxide from a basic aqueous residue; (c) recovering the water and the epoxide from the reactive distillation column as an overheads fraction; (d) condensing and phase separating the overheads fraction to form an organic overheads fraction including the epoxide and an aqueous overheads fraction including water; and (e) maintaining a liquid holdup per plate in the feed zone at a residence time of 10 seconds or less. | 02-04-2010 |
20100029960 | PROCESS FOR PRODUCING EPOXIDES - A process for producing epoxide, the process including contacting an organic phase including at least one halohydrin(s) with at least one aqueous phase including a base in a plug-flow mixer/reactor system to disperse the organic phase in the aqueous phase via a mixing device imparting a power-to-mass ratio of at least 0.2 W/kg to convert at least a portion of the at least one halohydrin to an epoxide. | 02-04-2010 |
20100331555 | PROCESS AND APPARATUS FOR PRODUCING AND PURIFYING EPICHLOROHYDRINS - A process and apparatus are disclosed for the purification of epichlorohydrin. The process includes distilling and/or fractionating a feed stream containing epichlorohydrin, dichlorohydrin(s), and one or more other substances, subjecting at least a portion of the liquid phase effluent to a dichlorohydrin dehydrochlorination process for converting residual dichlorohydrin(s) in the liquid phase effluent to epichlorohydrin, and recovering purified epichlorohydrin from the vapor phase effluent in which the distillation/fractionation pressure and/or temperature of step (1) is adjusted to retain at least 5 weight-percent epichlorohydrin in the liquid phase effluent. The apparatus for making purified epichlorohydrin includes a dehydrochlorination apparatus, a first liquid-vapor contacting apparatus, and a second liquid-vapor contacting apparatus connected to the dehydrochlorination apparatus for recycling a distillate to the dehydrochlorination apparatus. Advantages include more efficient recovery of epichlorohydrins and reduced capital investment in recovery equipment. | 12-30-2010 |
20120130095 | PROCESS FOR PRODUCING AN OXIRANE - A multiple liquid phase composition and process for preparing an oxirane product, such as epichlorohydrin, including a reaction mixture of: (a) at least one olefin, wherein the olefin is selected from one of (i) an aliphatic olefin or substituted aliphatic olefin, with the proviso that the aliphatic olefin is not propylene, (ii) a cycloaliphatic olefin, (iii) an aromatic olefin, (iv) a cycloaromatic olefin, and (v) mixtures thereof; (b) at least one peroxide compound, (c) at least one catalyst, and (d) and a solvent mixture; wherein the solvent mixture comprises at least (i) at least one alcohol or a combination of alcohols, and (ii) at least one non-reactive co-solvent; wherein the solvents are mixed at a predetermined concentration; wherein the non-reactive co-solvent has a different boiling point than the oxirane product; and wherein the oxirane product partitions into a high affinity solvent during the reaction. The process of the present invention advantageously produces a waste stream with no significant amount of sodium chloride (NaCl). In one embodiment, the present invention includes a process for preparing epichlorohydrin from allyl chloride and hydrogen peroxide including reacting (a) an allyl chloride with (b) hydrogen peroxide, in the presence of (c) a titanium silicalite-1 (TS-1) catalyst and (d) in the presence of a predetermined amount of a mixed solvent system; wherein the mixed solvent system includes at least (i) methanol and (ii) at least one non-reactive co-solvent. | 05-24-2012 |
20120130096 | PROCESS FOR PRODUCING PROPYLENE OXIDE - A multiple liquid phase composition and process for preparing propylene oxide including a reaction mixture of: (a) propylene, (b) at least one peroxide compound, (c) at least one catalyst, such as a titanium silicalite-1 (TS-I) catalyst, and (d) and a predetermined amount of a solvent mixture; wherein the solvent mixture comprises at least (i) at least one alcohol, such as methanol, and (ii) at least one non-reactive co-solvent; wherein the solvents are mixed at a predetermined concentration; wherein the non-reactive co-solvent has a different boiling point than propylene oxide; and wherein the resulting propylene oxide product partitions into a high affinity solvent during the reaction. The process of the present invention advantageously produces a waste stream with little or no significant amount of sodium chloride (NaCl). | 05-24-2012 |
20130267720 | PROCESS FOR PREPARING DINVINYLARENE OXIDES - A process for preparing a divinylarene oxide including (a) reacting (i) at least one divinylarene; (ii) at least one peroxycarboximidic acid; (iii) at least one solvent; and (iv) at least one basic compound, under reaction conditions to form a reaction of fluent containing a divinylarene oxide product; and then (b) evaporating the reaction effluent of step (a) to form a concentrate containing the divinylarene oxide product; and wherein the concentrate separates into two liquid phases. | 10-10-2013 |
20150232437 | PROCESS FOR RECOVERING DIVINYLARENE DIOXIDES - A process for recovering a divinylarene dioxide from a crude feed stream comprising the steps of: (a) providing an effluent reaction stream containing at least one divinylarene dioxide product and other compounds; and (b) separating/recovering the divinylarene dioxide product from the other compounds of the reaction effluent from step (a); wherein the percent recovery of the divinylarene dioxide product recovered comprises greater than about 85 percent; and wherein the percent purity of the divinylarene dioxide product recovered comprises greater than about 85 percent. | 08-20-2015 |
Patent application number | Description | Published |
20080198913 | Equalizer - Methods and apparatus to provide an equalizer for analog adaptive control are disclosed. An example equalizer described herein includes a high frequency amplifier to receive an input signal and to amplify a high frequency portion of the input signal, a low frequency amplifier to receive the input signal and to amplify a low frequency portion of the input signal, and a weight factor controller to control a gain of the high frequency amplifier and a gain of the low frequency amplifier. | 08-21-2008 |
20090135895 | Self-calibrated adaptive equalization system and methods of performing the same - A self-calibrating, adaptive equalization system for generating an ideal digital signal is disclosed. The adaptive equalization system includes an equalizer and a high-gain buffer. The equalizer includes a first equalizer loop that feeds-back a control voltage to the equalizer and the high-gain buffer that includes a second equalizer loop that feeds-back a high-pass-to-low-pass filter ratio signal. Each of the first and second equalizer loops has a high-pass and a low-pass filter, rectifying circuits for each of the filters, and an integrating circuit that compares signal energy output from the rectifiers. The adaptive equalization system generates an ideal digital signal. | 05-28-2009 |
20110199130 | LOW-POWER HIGH-SPEED DIFFERENTIAL DRIVER WITH PRECISION CURRENT STEERING - In bipolar CMOS or BiCMOS process technologies, drivers (such as mixed mode or hybrid mode drivers) using both bipolar and CMOS transistors (i.e., field effect transistors or FETs) may have undesirable properties, such as reduced speed, ringing, latch-up, or lower electrostatic discharge (ESD) performance. Here, a mixed or hybrid mode driver is provided that employs a current steering circuit (instead of voltages driven differential pair(s) as is done with conventional drivers) to generate pull-down currents that precisely match the voltages in the pull-up portions of driver. It increases the speed and produces smaller output common-mode voltage fluctuation over conventional drivers. Thus, the driver provided here can be produced in BiCMOS process technologies without the undesirable effects of conventional drivers. | 08-18-2011 |
20120013390 | DISPLAYPORT SWITCH - In versions 1.1a and 1.2 of the DISPLAYPORT™ standard, capacitors are used between a sourcing circuit and a switch for the auxiliary channel. As a result, these capacitors are generally uncharged when the switch activates the auxiliary channel, which can result in errors. Here, a switch is employed that uses precharge circuits to precharge these capacitors. Thus, errors due to charging of these capacitors can be reduced. | 01-19-2012 |
20120086489 | ADAPTIVE QUADRATURE CORRECTION FOR QUADRATURE CLOCK PATH DESKEW - Quadrature clocking schemes are widely used in modern communications systems, but often suffer from phase imbalance. Conventional solutions that attempt to address this phase imbalance, however, are generally large and use a substantial amount of power. Here, however, a correction circuit is provided that can locally correct for phase imbalance without the need for bulky and high power consuming circuitry. | 04-12-2012 |
20120275122 | USING A COUPLING ORTHOGONALIZATION APPROACH TO REDUCE CROSS-TALK - An apparatus is provided. The apparatus generally comprises a plurality of pairs of differential transmission lines. The plurality of pairs of differential transmission lines includes a set of pairs of differential transmission lines with each pair of differential transmission lines from the set of pairs of differential transmission lines including at least one twist to alternate current direction. Also, the plurality of differential transmission lines are arranged such that alternating current directions substantially eliminate cross-talk across the plurality of pairs of differential transmission lines. | 11-01-2012 |
20130107933 | LINEAR SYSTEM FOR LINK TRAINING | 05-02-2013 |
20140159814 | DIFFERENTIAL RECEIVER - A differential receiver with reduced common mode induced propagation delay variance. One implementation of a differential receiver includes a first differential amplifier, a second differential amplifier, and a first current source. The first differential amplifier includes a first transistor pair. The second differential amplifier includes a second transistor pair. The first current source is coupled to a drain node of a first transistor of the first transistor pair. The first current source is configured to generate a variable first current at the drain node as of function of a sum of a variable tail current of the first differential amplifier and a variable tail current of the second differential amplifier. | 06-12-2014 |
20140189628 | SYSTEM AND METHOD OF CROSSOVER DETERMINATION IN DIFFERENTIAL PAIR AND BONDWIRE PAIRS TO MINIMIZE CROSSTALK - A system is provided for use with circuit layout design data having a set of differential pairs and a set of bond wire pairs. A layout portion can receive the circuit layout design data. A crosstalk calculating portion can determine a first amount of crosstalk in a circuit corresponding to the circuit layout design data. A modifier can modify the circuit layout design data into modified circuit layout design data such that one of the set of differential pairs and the set of bond wire pairs includes a crossover. The crosstalk calculating portion can further determine a second amount of crosstalk in a circuit corresponding to the modified circuit layout design data. An optimizer can compare the first amount of crosstalk with the second amount of crosstalk to generate optimized circuit layout design data. A layout designer can output the optimized circuit layout design data. | 07-03-2014 |
Patent application number | Description | Published |
20090299058 | 3-3-DI-SUBSTITUTED-OXINDOLES AS INHIBITORS OF TRANSLATION INITIATION - Compositions and methods for inhibiting translation using 3-(5-tert-Butyl-2-Hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using 3-(5-tert-butyl-2-hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are described. | 12-03-2009 |
20100249201 | 3-3-Di-Substituted-Oxindoles As Inhibitors of Translation Initiation - Compositions and methods for inhibiting translation using 3-(5-tert-Butyl-2-Hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using 3-(5-tert-butyl-2-hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are described. | 09-30-2010 |
20110046367 | 3-3-DI-SUBSTITUTED-OXINDOLES AS INHIBITORS OF TRANSLATION INITIATION - Compositions and methods for inhibiting translation using 3-(5-tert-Butyl-2-Hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using 3-(5-tert-butyl-2-hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are described. | 02-24-2011 |
20120077759 | 3-3-Di-Substituted-Oxindoles as Inhibitors of Translation Initiation - Compositions and methods for inhibiting translation using 3-(5-tert-Butyl-2-Hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using 3-(5-tert-butyl-2-hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are described. | 03-29-2012 |