Patent application number | Description | Published |
20080241831 | Methods for detecting small RNA species - The invention provides a method of detecting small target nucleotide sequences, in particular, small RNA species that are present in a sample. The method generally comprises a poly-A polymerization step or a ligation step to add a universal sequence to the 3′-end of all RNA molecules, followed by a universal primer-mediated cDNA synthesis, solid-phase selection, assay oligo annealing, extension and PCR amplification/labeling. The method of the invention can be practiced to amplify and label a small amount of miRNA or other ncRNA. The resulting amplification product can be read out on a universal array or an array with miRNA-specific or ncRNA-specific probes. The invention has multiple embodiments, including methods, compositions, and kits. In general, the nucleic acids, compositions, and kits comprise materials that are useful in carrying out the methods of the invention or are produced by the methods, and that can be used to detect small target nucleic acid sequences present in samples, in particular, small RNA species. | 10-02-2008 |
20080242555 | MULTIPLEX NUCLEIC ACID REACTIONS - The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously. | 10-02-2008 |
20100015626 | MULTIPLEX NUCLEIC ACID REACTIONS - The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously. | 01-21-2010 |
20100311064 | MULTIPLEX NUCLEIC ACID REACTIONS - The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously. | 12-09-2010 |
20110152111 | MULTIPLEX NUCLEIC ACID ANALYSIS USING ARCHIVED OR FIXED SAMPLES - The present invention is directed to compositions and methods for multiplex analyses of nucleic acids from archival tissues. | 06-23-2011 |
20110153534 | Expression Profiles to Predict Relapse of Prostate Cancer - The present invention provides a method for preparing a reference model for cancer relapse prediction that provides higher resolution grading than Gleason score alone. The method encompasses obtaining from different individuals a plurality of prostate carcinoma tissue samples of known clinical outcome representing different Gleason scores; selecting a set of signature genes having an expression pattern that correlates positively or negatively in a statistically significant manner with the Gleason scores; independently deriving a prediction score that correlates gene expression of each individual signature gene with Gleason score for each signature gene in said plurality of prostate carcinoma tissue samples; deriving a prostate cancer gene expression (GEX) score that correlates gene expression of said set of signature genes with the Gleason score based on the combination of independently derived prediction scores in the plurality of prostate cancer tissue samples; and correlating said GEX score with the clinical outcome for each prostate carcinoma tissue sample. A set of signature genes is provided that encompasses all or a sub-combination of GI_2094528, KIP2, NRG1, NBL1, Prostein, CCNE2, CDC6, FBP1, HOXC6, MKI67, MYBL2, PTTG1, RAMP, UBE2C, Wnt5A, MEMD, AZGP1, CCK, MLCK, PPAP2B, and PROK1. Also provided a methods for predicting the probability of relapse of cancer in an individual and methods for deriving a prostate cancer gene expression (GEX) score for a prostate carcinoma tissue sample obtained from an individual. | 06-23-2011 |
20120109535 | Gene Expression Profiles to Predict Relapse of Prostate Cancer - The present disclosure provides a method for cancer relapse prediction that provides higher resolution grading than Gleason score alone. In particular, the method provides for prediction of prostate cancer relapse that correlates gene expression of each individual signature gene and deriving a prostate cancer gene expression (GEX) score in the plurality of prostate cancer tissue samples; and correlating said GEX score with the clinical outcome for each prostate carcinoma tissue sample. A set of signature genes is provided that encompasses all or a sub-combination of GI_2094528, KIP2, NRG1, NBL1, Prostein, CCNE2, CDC6, FBP1, HOXC6, MKI67, MYBL2, PTTG1, RAMP, UBE2C, Wnt5A, MEMD, AZGP1, CCK, MLCK, PPAP2B, and PROK1. | 05-03-2012 |
20120202704 | MULTI-SAMPLE INDEXING FOR MULTIPLEX GENOTYPING - A method for determining the presence of multiple nucleotide sequences of interest in multiple samples while preserving the identity of each sample, by contacting the samples with a plurality of probe sets. The probes are designed to indicate the presence of the sequences of interest and the identity of the sample containing the sequence of interest in complex mixtures. Applications of the method include genotyping, expression analysis, and identification of individual species in complex samples. Kits of probe sets for use in the methods are also provided. | 08-09-2012 |
20130244882 | MULTIPLEX NUCLEIC ACID REACTIONS - A method for detecting nucleic acids by (a) providing a sample having target nucleic acids, each nucleic acid having contiguous first, second, and third domains; (b) contacting the sample with probe sets to form hybridization complexes, wherein each probe set includes (i) a first probe having a sequence that is complementary to the first domain; and (ii) a second probe having a sequence substantially complementary to the third domain; (c) extending the first probes along the second domains of the complexes while the complexes are immobilized on a solid support; (d) ligating the extended first probes to the second probes to form templates; (e) amplifying the templates with primers that are complementary to the first and second priming sequences to produce amplicons; and (f) detecting the amplicons on the surface of a nucleic acid array. | 09-19-2013 |
20140045706 | METHODS AND SYSTEMS FOR HAPLOTYPE DETERMINATION - Embodiments of the present disclosure provide methods and systems for determining the haplotype of a biological sample. Particular embodiments provide methods for long range haplotyping of a genome. | 02-13-2014 |
20140114579 | HLA TYPING USING SELECTIVE AMPLIFICATION AND SEQUENCING - Presented herein are methods and compositions for determining haplotypes in a sample. The methods are useful for obtaining sequence information regarding, for example, HLA type and haplotype. Also presented herein are methods of determining haplotypes in a sample based on a plurality sequence reads. | 04-24-2014 |
20140315729 | DETECTION OF NUCLEIC ACID REACTIONS ON BEAD ARRAYS - The present invention is directed to methods and compositions for the use of micro sphere arrays to detect and quantify a number of nucleic acid reactions. The invention finds use in genotyping, i.e. the determination of the sequence of nucleic acids, particularly alterations such as nucleotide substitutions (mismatches) and single nucleotide polymorphisms (SNPs). Similarly, the invention finds use in the detection and quantification of a nucleic acid target using a variety of amplification techniques, including both signal amplification and target amplification. The methods and compositions of the invention can be used in nucleic acid sequencing reactions as well. All applications can include the use of adapter sequences to allow for universal arrays. | 10-23-2014 |
20140364323 | MULTI-SAMPLE INDEXING FOR MULTIPLEX GENOTYPING - A method for determining the presence of multiple nucleotide sequences of interest in multiple samples while preserving the identity of each sample, by contacting the samples with a plurality of probe sets. The probes are designed to indicate the presence of the sequences of interest and the identity of the sample containing the sequence of interest in complex mixtures. Applications of the method include genotyping, expression analysis, and identification of individual species in complex samples. Kits of probe sets for use in the methods are also provided. | 12-11-2014 |
20150203913 | MULTIPLEX NUCLEIC ACID REACTIONS - A method for detecting nucleic acids by (a) providing a sample having target nucleic acids, each nucleic acid having contiguous first, second, and third domains; (b) contacting the sample with probe sets to form hybridization complexes, wherein each probe set includes (i) a first probe having a sequence that is complementary to the first domain; and (ii) a second probe having a sequence substantially complementary to the third domain; (c) extending the first probes along the second domains of the complexes while the complexes are immobilized on a solid support; (d) ligating the extended first probes to the second probes to form templates; (e) amplifying the templates with primers that are complementary to the first and second priming sequences to produce amplicons; and (f) detecting the amplicons on the surface of a nucleic acid array. | 07-23-2015 |
Patent application number | Description | Published |
20090161746 | RECEIVER ADJUSTMENT BETWEEN PILOT BURSTS - A receiver may train its equalizer using consecutive pilot bursts, divide the traffic between the consecutive pilot bursts into multiple sub-segments, and interpolate the trained equalizer coefficients to obtain the coefficients for equalizing one or more of the sub-segments. The receiver may also determine signal to interference and noise ratio (SINR) values based on each of the consecutive pilot bursts, and interpolate the SINR for decoding one or more of the sub-segments. The receiver may be an access terminal receiver operating in a code division multiple access (CDMA) cellular system. | 06-25-2009 |
20090252099 | INTERFERENCE MANAGEMENT IN A WIRELESS COMMUNICATION SYSTEM USING FREQUENCY SELECTIVE TRANSMISSION - Interference that occurs during wireless communication may be managed by determination of a selected transmit waveform exhibiting a preferred channel quality. A method, apparatus and medium of communication determine a transmit waveform from among a plurality of allocated waveforms of an unplanned access point to an associated access terminal. The transmit waveform exhibiting a highest channel quality with an associated access terminal over others of the plurality of allocated waveforms is determined. Signals are transmitted according to the transmit waveform from the unplanned access point to the associated access terminal. | 10-08-2009 |
20100080189 | METHOD AND APPARATUS FOR PLUG-AND-PLAY VENUE-CAST CO-CHANNEL WITH WIDE-AREA NETWORK - A system, method, and apparatus for providing venue-cast service in a wireless access network are disclosed. A local transmitter can request reservation of air link resources on the wireless access network for a venue-cast transmission. The local transmitter can receive a forward link signal with a timing reference for data transmitted on the wireless access network such as, for example, the forward link signal in an EV-DO network or a FLO-based media distribution system. Based on the timing reference, the local transmitter can transmit venue-cast information in a same frequency band as the forward link signal utilizing the reserved air link resources. Optionally, the venue-cast system can include a collocated network repeater and the local transmitter can synchronize its timing and transmit power to the forward link signal from the repeater. | 04-01-2010 |
20120243515 | Increasing Capacity in Wireless Communications - Techniques to increase the capacity of a W-CDMA wireless communications system. In an exemplary embodiment, early termination ( | 09-27-2012 |
20120281675 | Increasing Capacity in Wireless Communications - Techniques to increase the capacity of a W-CDMA wireless communications system. In an exemplary embodiment, early termination ( | 11-08-2012 |
20130195097 | METHOD AND APPARATUS FOR ENABLING ENHANCED CQI UPDATE FREQUENCY - A method and apparatus for facilitating downlink data transmission in a TD-SCDMA system is provided. The method may comprise receiving, from a Node B, a channel quality indicator (CQI) request, wherein the CQI request is not associated with a payload transmission. | 08-01-2013 |
20130201959 | METHOD AND APPARATUS FOR MAKE-BEFORE-BREAK HANDOVER IN A TD-SCDMA SYSTEM - A system and method enable make-before-break handover from a source cell to a target cell in a TD-SCDMA system. According to various aspects of the present disclosure, a wireless link is established with the target cell while maintaining the call with the source cell. The communication between the mobile station and the respective source and target cells may be multiplexed utilizing time division multiplexing or frequency division multiplexing. When utilizing time division multiplexing, the allocation between the respective source and target cells may be made slot-by-slot in a subframe, or subframe-by-subframe in a radio frame. | 08-08-2013 |
20130223411 | METHOD AND APPARATUS FOR FACILITATING EFFECTIVE SCHEDULING GRANTS - A method and apparatus for effectively facilitating grant scheduling is provided. The method may comprise transmitting, by a user equipment (UE), a grant request, wherein the grant request includes a UE power headroom (UPH) value, and receiving, from a Node B, a scheduling grant, wherein the scheduling grant is derived from the transmitted UPH. | 08-29-2013 |
20130242826 | METHOD AND APPARATUS FOR DISCONTINUOUS RECEPTION IN USER EQUIPMENT FOR POWER SAVINGS - Methods and apparatuses to power off a modem receiver or components of the receiver at a time prior to the end of the frame based on data in the frame being received and properly decoded before the end of the frame. In an aspect, the apparatuses and methods provide power saving in a wireless device, and include receiving data within a frame at a user equipment, determining whether all payload packet data has been correctly decoded prior to an end of the frame, and powering down a receiver component for a portion of a remainder of the frame in response to determining that all payload packet data has been correctly decoded and where a first time period to a next scheduled overhead hit transmission period of a slot in the frame is greater than a second time period corresponding to a warm-up period for the receiver component. | 09-19-2013 |
20130266097 | Early Termination Schemes for Turbo Decoding in a Wireless Communication System - Certain embodiments provide methods that may allow for improvements in performance and power consumption by terminating the turbo decoding process early when one of at least two test criterion is satisfied in communications systems, including UMTS, WCDMA, and TD-DCMA. | 10-10-2013 |
20130329714 | HOME NETWORKING WITH INTEGRATED CELLULAR COMMUNICATION - A method, an apparatus, and a computer program product for wireless communication are provided. The apparatus may be an intermediate gateway. The intermediate gateway may receive a first Internet protocol (IP) packet of a first data flow for transmission to a device, determine a first quality of a cellular communication link established with the device and a second quality of at least one local area communication link established with the device, attach a header to the first IP packet when the second quality is closer to a quality requirement of the first IP packet than the first quality, the header being used to tunnel the first IP packet to the device via the at least one local area communication link, and transmit the first IP packet to the device via the at least one local area communication link based on at least the first and second qualities. | 12-12-2013 |
20140036698 | ITERATIVE COVARIANCE INVERSION BASED ON LINEAR RECEIVER DESIGNS - A method of wireless communication includes receiving a wireless signal at a linear receiver, and iteratively computing an inverted covariance matrix in frequency domain, one channel code at a time. The method also includes computing receiver demodulation coefficients based on the inverted covariance matrix and the frequency domain channel estimate or time domain channel estimate. The method further includes deriving a transmitter symbol based on a received signal vector and the coefficients. | 02-06-2014 |
20140056239 | METHODS AND APPARATUS FOR POWER CONTROL FOR HIGH-EFFICIENCY SCHEDULING IN TD-SCDMA HSUPA - Certain aspects of the present disclosure propose techniques for power control for high-efficiency scheduling for Time Division Synchronous Code Division Multiple Access (TD-SCDMA) High Speed Uplink Packet Access (HSUPA). The basic principle of this power control for a scheduled Enhanced Dedicated Channel (E-DCH) Physical Uplink Channel (E-PUCH) is that all information for a transport block size (TBS) decision is made available at a user equipment (UE). Certain aspects provide a method for wireless communications. The method generally includes receiving, from a UE, an uplink signal, determining a reference uplink power level based on a filtered interference power of the received signal, and transmitting an indication of the reference uplink power level to the UE. | 02-27-2014 |
20140233416 | INTERFERENCE MANAGEMENT IN A WIRELESS COMMUNICATION SYSTEM USING FREQUENCY SELECTIVE TRANSMISSION - Interference that occurs during wireless communication may be managed by determination of a selected transmit waveform exhibiting a preferred channel quality. A method, apparatus and medium of communication determine a transmit waveform from among a plurality of allocated waveforms of an unplanned access point to an associated access terminal. The transmit waveform exhibiting a highest channel quality with an associated access terminal over others of the plurality of allocated waveforms is determined. Signals are transmitted according to the transmit waveform from the unplanned access point to the associated access terminal. | 08-21-2014 |
20140247814 | METHODS AND APPARATUS FOR SPECIAL BURST TRANSMISSIONS TO REDUCE UPLINK AND DOWNLINK INTERFERENCE FOR TD-SCDMA SYSTEMS - A method and apparatus in wireless communications is provided. The method may include determining an occurrence of a special burst time slot, and obtaining one or more control symbols located in a first data field and a second data field of the special burst time slot. | 09-04-2014 |
20140285684 | DETECTING COUNTERFEIT PRINT MATERIAL WITH CAMERA-EQUIPPED COMPUTING DEVICE - An apparatus, system, and method for examining authenticity of printed material and distinguishing between original printed material and counterfeit printed material is disclosed. In one embodiment, the method is performed by a mobile device. The mobile device recognizes a reference point on a page of the printed material, computes a color balance ratio for that reference point, and compares the computed color balance ratio to an expected value for original printed material. Based on the comparison between the computed color balance ratio and the expected value, a determination is made as to the authenticity of the printed material. If the printed material is authentic, the mobile device may provide supplementary, complementary and/or additional information and content, for example, information related to the page or chapter of the printed material. If the printed material is not authentic, the mobile device may inhibit the presentation of additional material. | 09-25-2014 |
20150056933 | TX ANTENNA SELECTION FOR LTE IN MULTIPLE RADIO DEVICES - Device antennas may be allocated such that a non-LTE module (e.g., GSM module or 1x module) shares the same antenna with an LTE DRx module. This may lead to degradation of a non-LTE voice service when the LTE DRx module performs LTE transmit antenna selection causing the non-LTE module to be switched to a different antenna during reception/transmission of voice slots, resulting in a loss of slots. Accordingly, a method, an apparatus, and a computer program product for controlling antenna switching are provided. The apparatus facilitates a first radio module to use a first antenna for performing a first operation, detects that a second radio module will attempt to use the first antenna during transmit antenna selection for performing a second operation, and determines whether to switch use of the first antenna from the first radio module to the second radio module based on a type of the first operation. | 02-26-2015 |
20150063150 | MEASUREMENT REPORTING IN UNLICENSED SPECTRUM - Systems and methods for measurement reporting in unlicensed spectrum are disclosed. A user device may perform one or more signaling measurements in an unlicensed frequency band in accordance with a first Radio Access Technology (RAT) and send feedback information relating to the signaling measurements to a small cell base station, with the feedback information being sent in accordance with a second RAT. A message may be sent to the user device in accordance with the second RAT that configures the user device to perform the one or more signaling measurements in the unlicensed frequency band. | 03-05-2015 |
20150063151 | OPPORTUNISTIC SUPPLEMENTAL DOWNLINK IN UNLICENSED SPECTRUM - Systems and methods for managing communication in an unlicensed band of frequencies to supplement communication in a licensed band of frequencies in unlicensed spectrum are disclosed. The management may comprise, for example, monitoring utilization of resources currently available to a first Radio Access Technology (RAT) via at least one of a Primary Cell (PCell) operating in the licensed band, a set of one or more Secondary Cells (SCells) operating in the unlicensed band, or a combination thereof. Based on the utilization, a first SCell among the set of SCells may be configured or de-configured with respect to operation in the unlicensed band. | 03-05-2015 |
20150063323 | CHANNEL SELECTION TO REDUCE INTERFERENCE TO A WIRELESS LOCAL AREA NETWORK FROM A CELLULAR NETWORK - The disclosure is related to selecting an operating channel for a cellular network to reduce interference to a wireless local area network (WLAN) operated by a small cell comprising a WLAN access point and a cellular network modem. The small cell performs a channel scan of available channels, determines whether or not there is a clean channel to be the operating channel for the cellular network based on the channel scan, wherein a clean channel comprises a channel that interferes with the WLAN less than a WLAN interference threshold, and selects the clean channel as the operating channel for the cellular network based on the clean channel being available or turns off the cellular network based on no clean channel being available. | 03-05-2015 |
20150223077 | METHODS FOR INTER-OPERATOR COEXISTENCE ON SHARED SPECTRUM OR UNLICENSED BANDS - To enable coexistence in unlicensed bands or other shared spectrum, operators that deploy cellular coverage in unlicensed bands can broadcast and receive over-the-air (OTA) signaling messages that carry coexistence information such that the operators can adjust one or more parameters used to provide the cellular coverage in the unlicensed bands and thereby enable inter-operator coexistence. For example, the operators may coordinate the particular OTA signaling configuration used to carry the coexistence information and thereby enable each operator to learn information that the other operator(s) are using and thereby reduce interference on time, frequency, and/or spatial resources that may be shared among the operators providing the cellular coverage in the unlicensed bands. Furthermore, a user equipment (UE) that receives and decodes the OTA signaling messages exchanged among the operators may adjust one or more measurement parameters and/or operating parameters according to the coexistence information carried in the OTA signaling messages. | 08-06-2015 |
20150236782 | CARRIER SENSE ADAPTIVE TRANSMISSION (CSAT) MEASUREMENTS IN SHARED SPECTRUM - Techniques for managing operation on a communication medium shared between Radio Access Technologies (RATs) are disclosed. The management may comprise, for example, monitoring the medium for first RAT signaling in accordance with a first RAT; determining a utilization metric associated with utilization of the medium by the first RAT signaling; cycling operation in accordance with a second RAT between activated periods and deactivated periods of communication over the medium in accordance with a Time Division Multiple Access (TDM) communication pattern based on the utilization metric; and periodically disabling the cycling to provide an AOS period of activated communication over the medium for operation in accordance with the second RAT, with the AOS period being longer than an individual activated period of the TDM communication pattern. The management may also comprise, for example, techniques for enabling/disabling monitoring by an access terminal in accordance with the TDM communication pattern. | 08-20-2015 |
20150296508 | ADAPTIVELY USING SUBFRAMES FOR RADAR DETECTION IN UNLICENSED SPECTRUM - Systems and methods for adaptively using subframes for radar detection in unlicensed spectrum are disclosed. The systems and methods include scheduling a first set of subframes in a frame duration for traffic based at least in part on a first configuration for communications in an unlicensed frequency band. Further, the systems and methods include scheduling, based at least in part on the first configuration, a second set of subframes in the frame duration for detection of a primary user of the unlicensed frequency band. Moreover, the systems and methods include adjusting a number of subframes in the first and second set of subframes based on a second configuration for communications, wherein the second configuration for communications is identified based on a type of primary user being detected. | 10-15-2015 |
20150305030 | INTERLACED CARRIER SENSE ADAPTIVE TRANSMISSION (CSAT) CO-EXISTENCE IN SHARED SPECTRUM - Techniques for managing operation over a communication medium shared between Radio Access Technologies (RATs) are disclosed. In one example, one or more parameters of a Time Division Multiplexing (TDM) communication pattern may be set to define activated periods and deactivated periods for communication over the medium. A first interlace may be selected among a plurality of interlaces for communication over the medium, the first interlace being reserved for a first operator. During the first interlace, transmission over the medium may be cycled in accordance with the TDM communication pattern, and deactivated during a second interlace among the plurality of interlaces that is reserved for a second operator. | 10-22-2015 |
Patent application number | Description | Published |
20090134046 | INSTRUMENTS AND METHODS FOR MIXING THE CONTENTS OF A DETECTION CHAMBER - A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle. | 05-28-2009 |
20090136913 | Gravity-Assisted Mixing Methods - A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle. | 05-28-2009 |
20090136963 | METHODS OF CONCENTRATING AN ANALYTE - A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle. | 05-28-2009 |
20090142745 | INSTRUMENTS AND METHODS FOR EXPOSING A RECEPTACLE TO MULTIPLE THERMAL ZONES - A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle. | 06-04-2009 |
20090142771 | Methods and Instruments for Processing a Sample in a Multi-Chambered Receptacle - A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle. | 06-04-2009 |
20100196908 | SYSTEMS AND METHODS FOR DETECTING A SIGNAL AND APPLYING THERMAL ENERGY TO A SIGNAL TRANSMISSION ELEMENT - A signal detection system configured for detecting a signal emitted by the contents of a reaction receptacle is also configured to apply thermal energy to a portion of the reaction receptacle to affect a reaction occurring within the reaction receptacle. More particularly, a system for detecting electromagnetic radiation emitted by the contents of a reaction receptacle includes a transmission element configured for transmitting electromagnetic radiation from the contents of the receptacle, a thermal element associated with the transmission element and configured to apply thermal energy to at least a portion of the receptacle, and a detector configured to receive electromagnetic radiation from the transmission element and to generate a signal corresponding to a characteristic of the electromagnetic radiation received by the detector. | 08-05-2010 |
20110189661 | GRAVITY-ASSISTED MIXING METHODS - A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle. | 08-04-2011 |
20110275087 | INSTRUMENTS AND METHODS FOR MIXING THE CONTENTS OF A DETECTION CHAMBER - A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle. | 11-10-2011 |
20120231456 | INSTRUMENTS AND METHODS FOR MIXING THE CONTENTS OF A DETECTION CHAMBER - A receptacle having interconnected chambers arranged to permit multiple process steps to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle. | 09-13-2012 |
20130288348 | INSTRUMENTS FOR MIXING THE CONTENTS OF A DETECTION CHAMBER - A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle. | 10-31-2013 |
Patent application number | Description | Published |
20080279170 | METHOD AND APPARATUS FOR MULTIPLEXING CDM PILOT AND FDM DATA - Techniques for sending control information in a wireless communication system are described. In an aspect, a user equipment (UE) may send data for control information in a resource block with frequency division multiplexing (FDM) and may send pilot in the resource block with frequency-domain code division multiplexing (CDM). The UE may determine multiple groups of subcarriers to use to send data in multiple symbol periods of the resource block based on a predetermined pattern or a pseudo-random hopping pattern. Each group may include consecutive subcarriers to support localized FDM. The multiple groups may include different subcarriers to provide frequency diversity and possibly interference averaging. The UE may send modulation symbols for data (e.g., in the time domain) on the multiple groups of subcarriers in the multiple symbol periods. The UE may send a reference signal sequence for pilot on multiple subcarriers in each symbol period for pilot. | 11-13-2008 |
20090141690 | METHOD AND APPARATUS FOR UPLINK CONTROL SIGNALING - A transmitter in a wireless network transmits joint channel quality indicator (CQI) and data packet acknowledgement (Ack) or just CQI within the same subframe without uplink data transmission that can be readily detected at a receiver. When a short cyclic prefix (CP) is appropriate, a first approach utilizes a pilot aided signaling by using two different Walsh covers for the pilots to signal CQI vs. CQI+ACK. When a long CP is appropriate with one pilot, two different code designs are provided for CQI and CQI+ACK that only optimize the code book for each mode separately, but also maximize the distance between these two code spaces. Various coset based approaches are described to search for such linear block codes. Initial results showed good codes can be found based on the coset based approach to minimize the false alarm and misdetection. | 06-04-2009 |
20090196247 | SIMULTANEOUS TRANSMISSION OF ACKNOWLEDGEMENT, CHANNEL QUALITY INDICATOR AND SCHEDULING REQUEST - Systems and methodologies are described that facilitate simultaneous transmission of control information in a single sub-frame. For instance, simultaneous transmission can maintain single carrier waveforms for a control channel even when a plurality of information types is scheduled in concurrently. Channel quality indicators, scheduling requests and acknowledgement messages can be jointly coded. In addition, reference symbols in a sub-frame can be modulated to indicate values associated with a scheduling request or an acknowledgement message. Moreover, in situations where channel quality indicators, scheduling requests and or acknowledgement messages are simultaneously scheduled, one or more can be dropped. Further, a single carrier constraint can be relaxed to enable simultaneous transmission of information in the sub-frame at different frequencies. | 08-06-2009 |
20090245284 | ENCODING AND DECODING OF CONTROL INFORMATION FOR WIRELESS COMMUNICATION - Techniques for sending control information in a wireless communication system are described. In one design, a user equipment (UE) may map first information (e.g., CQI information) to M most significant bits (MSBs) of a message and may map second information (e.g., ACK information) to N least significant bits (LSBs) of the message if the second information is sent, where M≧1 and N≧1. The UE may encode the message with a block code, e.g., encode the M MSBs with the first M basis sequences of the block code and encode the N LSBs with the next N basis sequences of the block code. The second information may include N ACK bits. The UE may set each ACK bit to a first value for an ACK or to a second value for a NACK. The second value may also be used for discontinuous transmission (DTX) of ACK information. | 10-01-2009 |
20090296850 | ENCODED CONTROL CHANNEL INFORMATION INTERLEAVING - Systems and methodologies are described that facilitate interleaving encoded control channel information for transmission over an uplink channel. The encoded control channel information, for example, can include encoded Channel Quality Indicator (CQI) information, encoded Precoding Matrix Indicator (PMI) information, and/or Rank Indicator (RI) information. CQI information, PMI information, and/or RI information can be encoded at an access terminal, for instance, by applying a punctured Reed Muller block code to generate a sequence of encoded bits. The encoded bits can be interleaved to reorder the sequence utilizing one or more interleaving approaches. Examples of interleaving approaches that can be leveraged include prime number based interleaving, generalized bit reversal interleaving, column-row interleaving with column bit reversal, and/or M-sequence based interleaving. Further, the reordered sequence of encoded bits can be transmitted to a base station over an uplink channel. | 12-03-2009 |
20100232311 | CONCURRENT TRANSMISSION OF ACK/NACK, CQI AND CQI FROM USER EQUIPMENT - A wireless communications method is provided. The method includes providing a multi-codeword transmission that includes ACK/NACK and discontinuous transmission (DTX) information. The method also includes ordering reference signal (RS) symbols in proximity to at least one other reference signal symbol to facilitate signaling of additional states and enabling spreading gain to be increased. | 09-16-2010 |
20110044269 | METHODS AND APPARATUS FOR BLIND INTERFERENCE DECREASE/CANCELLATION TECHNIQUES - A method, an apparatus, and a computer program product for wireless communication are provided in which one or more semi-static parameters associated with at least one neighboring eNode B (eNB) and an interfering user equipment (UE) are detected, at an eNB, and a blind interference reduction scheme based on the one or more detected semi-static parameters to reduce a signal from the interfering UE is applied. | 02-24-2011 |
20110268230 | OPTIMIZING A RECEIVER FOR MULTIPLE ANTENNA CONFIGURATIONS - A method for optimizing a multiple input multiple output (MIMO) receiver for multiple antenna configurations is disclosed. A noise covariance is determined based on a noise estimate of a wireless signal. A Cholesky decomposition matrix is determined based on the noise covariance. A whitening matrix is determined based on the Cholesky decomposition matrix. The wireless signal is whitened using the whitening matrix. | 11-03-2011 |
20110280346 | METHOD AND APPARATUS FOR FACILITATING TRI-STATE DECODING ON A SHARED UPLINK CHANNEL - Methods, apparatuses, and computer program products are disclosed for facilitating decoding a communication received from a wireless terminal. Encoded bits are received from the wireless terminal via a shared uplink channel, and a plurality of acknowledgment tones are identified within the encoded bits. A correlation value is ascertained corresponding to a correlation between detected bits within the plurality of acknowledgment tones and valid bits corresponding to any of a plurality of valid acknowledgment codewords. A determination is then made as to whether the plurality of acknowledgment tones includes information corresponding to a discontinuous transmission by comparing the correlation value to a threshold value. | 11-17-2011 |
20110292917 | SYSTEM AND METHOD FOR TIMING ADJUSTMENT TO PROTECT CQI - Certain aspects of the present disclosure propose methods for protecting channel quality indicator (CQI) modulation symbols in a subframe (e.g., a localized frequency division multiplexing (LFDM) subframe). For some aspects, a timing adjustment method may be utilized to adjust time of a UE with respect to an eNodeB. The timing adjustment method may introduce a positive time offset to be used for reducing time mismatch between the UE and the eNodeB. In another aspect, a buffer may be used at the eNodeB to store symbols received by the eNodeB before removing the cyclic prefix information from the subframe. The eNodeB may use the stored symbols and an artificial time delay to ensure that the CQI information is protected. For some aspects, the CQI modulation symbols may not be located at the beginning of an LFDM symbol. | 12-01-2011 |
20120008511 | BLIND UPLINK INTERFERENCE CANCELLATION IN WIRELESS NETWORKING - Blind interference cancellation is described for wireless networks in which a subject base station or cancellation apparatus obtains semi-static information for at least one of its neighboring cells. The base station measures the noise level of each of the neighboring cells based on samples it takes of uplink transmissions in each of the neighboring cells. The neighboring cells are then ranked for interference cancellation based on their relative noise levels. The base station performs discontinuous transmission (DTX) detection to identify at least one interfering user equipment (UE) in the neighboring cell and cancels interference attributable to those identified interfering UEs. The DTX detection and cancelation are then repeated for the remaining neighboring cells in the order they are ranked. | 01-12-2012 |
20120008516 | TTL OPERATIONS FOR SMALL RB ASSIGNMENTS - Certain aspects of the present disclosure provide techniques for wireless communications, wherein more accurate timing offset calculations may be achieved for uplink transmissions with a relatively small number of assigned resources. | 01-12-2012 |
20120057535 | UPLINK COORDINATED MULTIPOINT COMMUNICATIONS IN A WIRELESS NETWORK - Devices, systems, methods and/or computer program products are provided to facilitate coordinated multipoint transmission and reception of communications in a wireless network. In some scenarios, different set of resources are allocated for uplink transmissions of multiple user equipment. In other scenarios collision avoidance and/or multiplexing techniques are used to enable reception and decoding of multiple uplink transmissions on the same or overlapping resources at the same time. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules that allow a reader to quickly ascertain the disclosed subject matter. Therefore, it is to be understood that it should not be used to interpret or limit the scope or the meaning of the claims. | 03-08-2012 |
20120184314 | DETERMINING AN UPLINK CONTROL PATH WITH BLIND DECODING - In an aspect, a method assists with blind decoding of uplink control signals on a Physical Uplink Shared Channel (PUSCH) and Physical Uplink Control Channel (PUCCH). The method assists in determining the uplink control path in the event a user equipment (UE) misses an uplink grant and blind decoding occurs. It is determined whether an uplink acknowledgement, rank indicator, and/or channel quality indicator are found on a PUSCH. If not, it is determined whether a scheduling request is expected and whether special handling for the scheduling request is indicated. Depending on those determinations, and whether any decoding attempts for uplink signals are successful, either the PUSCH or PUCCH is selected as the uplink control path. | 07-19-2012 |
20130114450 | METHODS AND APPARATUS FOR PROXIMITY DETECTION - Certain aspects of the present disclosure provide methods, apparatus, and computer-program products for the detection of potentially interfering or interfering user equipment (UE) in the proximity of a detecting entity. The detecting entity may be a base station or a UE. In an aspect, the proposed detecting scheme utilizes semi-static system information from one or more neighboring base stations (BSs), and identifies a neighbor BS's UE that causes interference in the physical uplink control channel (PUCCH). The proposed detecting scheme may also identify corresponding resources that are allocated to an interfering UE by the interfering neighbor base station. In aspects, detecting schemes may not utilize information from one or more neighboring BSs. | 05-09-2013 |
20130114519 | ENHANCED ADAPTIVE GAIN CONTROL IN HETEROGENEOUS NETWORKS - In wireless communications, adaptive gain control may be performed by scaling of signals before and after a transform. A received signal power may be non-causally scaled to a first level within a desired range before transforming the received signal. The scaled signal is transformed between a time domain to a frequency domain and then its power is again non-causally scaled based on the first level. A feed forward circuit may be used in the power scaling. Different portions of the signal may be power adjusted independently of other portions. The different portions may be separated on a per-channel basis. Power scaling may be done on a symbol-by-symbol basis. | 05-09-2013 |
20130176881 | METHODS AND APPARATUS FOR BLIND INTERFERENCE DECREASE/CANCELLATION TECHNIQUES - A method, an apparatus, and a computer program product for wireless communication are provided in which one or more semi-static parameters associated with at least one neighboring eNode B (eNB) and an interfering user equipment (UE) are detected, at an eNB, and a blind interference reduction scheme based on the one or more detected semi-static parameters to reduce a signal from the interfering UE is applied. | 07-11-2013 |
20140198677 | CHANNEL STATE INFORMATION AND ADAPTIVE MODULATION AND CODING DESIGN FOR LONG-TERM EVOLUTION MACHINE TYPE COMMUNICATIONS - A method, an apparatus, and a computer program product for wireless communication are provided. The apparatus may be a UE. The UE determines CSI. The UE determines whether to send the CSI based on at least one of a timer or a threshold. The UE sends the CSI upon determining to send the CSI. The UE may send the CSI in a MAC header upon determining to send the CSI. When the UE determines whether to send the CSI based on the threshold, the UE may determine whether to send the CSI based on a difference between the CSI and reference CSI. The UE may determine the reference CSI based on at least one of previously reported CSI, fixed CSI, or an MCS of a received data transmission from a base station. The UE may send CSI to the base station in an initial connection setup with the base station. | 07-17-2014 |
20150110043 | Simultaneous Transmission of Acknowledgement, Channel Quality Indicator and Scheduling Request - Systems and methodologies are described that facilitate simultaneous transmission of control information in a single sub-frame. For instance, simultaneous transmission can maintain single carrier waveforms for a control channel even when a plurality of information types is scheduled in concurrently. Channel quality indicators, scheduling requests and acknowledgement messages can be jointly coded. In addition, reference symbols in a sub-frame can be modulated to indicate values associated with a scheduling request or an acknowledgement message. Moreover, in situations where channel quality indicators, scheduling requests and or acknowledgement messages are simultaneously scheduled, one or more can be dropped. Further, a single carrier constraint can be relaxed to enable simultaneous transmission of information in the sub-frame at different frequencies. | 04-23-2015 |